Growth rate of the vomer in normal and cleft lip and palate human fetal specimens.

Abstract:

:The present study, part of an ongoing investigation of normal and dysmorphic development of the human fetal oronasal capsule, examined the rate of growth of the vomer. For comparative purposes, 29 human fetal specimens (20 "normal" and 9 cleft lip and palate [CLP]) were celloidin embedded, sectioned, stained with hematoxylin and eosin, and serially digitized. The specimens ranged from 8 to 21 weeks in postmenstrual age. The application of a well-documented three-dimensional reconstruction technique provided quantification of several aspects of the vomer. CLP vomer length and volume were growing at a faster rate in the 8 to 21 week age range. Growth curves were produced by plotting length and volume against postmenstrual age and a significant difference was noted between the slopes (growth rate) of the linear component of the normal and CLP growth curves for vomer length (p less than .001) and volume (p less than .001). This study tested the hypothesis of a more rapidly growing 8 to 21 week CLP vomer and observed that the growth trends of the CLP vomer are similar to those of the CLP nasal septum, which also was found to possess a significantly larger (p less than .001) volumetric growth rate throughout the course of the vomer. Comparative findings suggest that a pathogenetic correlate of CLP is the rapid enlargement of the midline structures of the oral and nasal capsules.

authors

Kimes KR,Mooney MP,Siegel MI,Todhunter JS

doi

10.1597/1545-1569_1992_029_0038_grotvi_2.3.co_2

keywords:

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

38-42; discussion 42-3

issue

1

eissn

1055-6656

issn

1545-1569

journal_volume

29

pub_type

杂志文章
  • The role of screening audiometry in the management of otitis media with effusion in children with cleft palate in northern ireland.

    abstract:OBJECTIVE:To determine uptake and outcome of hearing screening in the cleft palate population in Northern Ireland (NI) and the rate of ventilation tube (VT) insertion over a 3-year period. DESIGN:In NI, hearing screening is offered in the neonatal period, at 9 months in the community, and at 2.5 years in the joint cle...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/12-276

    authors: Eastwood MP,Hoo KH,Adams D,Hill C

    更新日期:2014-07-01 00:00:00

  • Treatment outcome after one-stage repair in children with complete unilateral cleft lip and palate assessed with the Goslon Yardstick.

    abstract:OBJECTIVE:To compare results of Golson Yardstick measurement of dental arch relationships in a sample of 10-year-old Polish children with results of the Golson measurement in published reports. MATERIALS AND METHODS:Plaster models of 28 consecutively treated subjects with unilateral cleft lip and palate (UCLP) that wa...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/07-242.1

    authors: Fudalej P,Hortis-Dzierzbicka M,Obloj B,Miller-Drabikowska D,Dudkiewicz Z,Romanowska A

    更新日期:2009-07-01 00:00:00

  • Congenital trilobe tongue associated with cleft palate: a rare anomaly.

    abstract::Cleft of the palate and congenital anomaly of the tongue is a rare occurrence. A child with the tongue in three segments is being presented for the first time in the literature. This child also had partial cleft palate. The cleft palate was repaired at 7 months of age, and the tongue was reconstructed at 15 months. Th...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/13-117

    authors: Agrawal K,Mulla RU,Srivastava R,Sharma S

    更新日期:2014-11-01 00:00:00

  • Measuring Symmetry in Children With Cleft Lip. Part 3: Quantifying Nasal Symmetry and Nasal Normalcy Before and After Unilateral Cleft Lip Repair.

    abstract:OBJECTIVE:The purpose of this project was to develop objective computer-based methods to measure nasal asymmetry and abnormality in children undergoing treatment of unilateral cleft lip (UCL) and to determine the correlation of these measures to clinical expectations. PARTICIPANTS:Thirty infants with UCL undergoing cl...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/16-035

    authors: Liang S,Shapiro L,Tse R

    更新日期:2017-09-01 00:00:00

  • Placement of endosseous implants in grafted alveolar clefts.

    abstract:OBJECTIVE:The purpose of this study was to determine the optimal timing for placement and to evaluate short- and long-term outcomes of endosseous implants in bone-grafted alveolar clefts. DESIGN:Fourteen patients who underwent alveolar cleft bone grafting (ACBG) and closure of an oronasal fistula followed by restorati...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_1997_034_0520_poeiig_2.3.co_2

    authors: Kearns G,Perrott DH,Sharma A,Kaban LB,Vargervik K

    更新日期:1997-11-01 00:00:00

  • Contributions of PTCH gene variants to isolated cleft lip and palate.

    abstract:OBJECTIVE:Mutations in patched (PTCH) cause the nevoid basal cell carcinoma syndrome (NBCCS), or Gorlin syndrome. Nevoid basal cell carcinoma syndrome may present with developmental anomalies, including rib and craniofacial abnormalities, and predisposes to several tumor types, including basal cell carcinoma and medull...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/04-169r.1

    authors: Mansilla MA,Cooper ME,Goldstein T,Castilla EE,Lopez Camelo JS,Marazita ML,Murray JC

    更新日期:2006-01-01 00:00:00

  • Phenotypic and molecular analyses of A/WySn mice.

    abstract:OBJECTIVE:Since its first description, the A strain of mice have been utilized extensively as models to study the processes involved in clefting of the midfacial region. Of the A substrains, the A/WySn has a spontaneous rate of clefting of the lip of about 20% to 30%. The A/WySn mouse model was utilized in this study t...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_2001_038_0486_pamaoa_2.0.co_2

    authors: Gong SG

    更新日期:2001-09-01 00:00:00

  • Habilitation of patients with clefts: parent and child ratings of satisfaction with appearance and speech.

    abstract::This study examined ratings regarding satisfaction with facial appearance and speech performance from 495 parent-child pairs. Data were obtained from school-aged children (5-18 years old) and their parents using standardized independent interviews. Results revealed that 54 percent of the children with cleft lip (CL) o...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_1992_029_0262_hopwcp_2.3.co_2

    authors: Broder HL,Smith FB,Strauss RP

    更新日期:1992-05-01 00:00:00

  • Craniofacial morphogenesis workshop report.

    abstract::The following report highlights the discussions and interaction at the workshop on craniofacial morphogenesis, sponsored by The Human Frontier Science Program, held in April 1993 at the University of Iowa. A brief summary of selected sessions is included to exemplify the benefits of bringing together individuals from ...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type:

    doi:10.1597/1545-1569_1994_031_0230_cmwr_2.3.co_2

    authors: Solursh M,Murray J

    更新日期:1994-05-01 00:00:00

  • Postpalatoplasty Eustachian tube function in young children with cleft palate.

    abstract:OBJECTIVE:To characterize Eustachian tube function using the forced response test in young children with cleft palate with or without cleft lip after palatoplasty with tympanostomy tubes inserted prepalatoplasty and compare these results with those of a 1986 study that evaluated a similar population using identical met...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/11-065

    authors: Alper CM,Losee JE,Mandel EM,Seroky JT,Swarts JD,Doyle WJ

    更新日期:2012-07-01 00:00:00

  • The Tessier number 5 facial cleft: surgical strategies and outcomes in six patients.

    abstract::The Tessier no. 5 facial cleft is an extremely rare congenital malformation. Only 26 cases have been described in the English-language literature. The cleft begins in the upper lip just medial to the oral commissure, extending across the cheek as a groove ending at the junction of the middle and lateral thirds of the ...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/07-192.1

    authors: da Silva Freitas R,Alonso N,Shin JH,Busato L,Dall'Oglio Tolazzi AR,de Oliveria e Cruz GA

    更新日期:2009-03-01 00:00:00

  • Pierre Robin sequence in Denmark: a retrospective population-based epidemiological study.

    abstract:OBJECTIVE:To give an epidemiological description of the clinical entity given the name Pierre Robin sequence, defined by retro- and micrognathia, cleft palate, and respiratory distress and describe other malformations and possible intrauterine impairment. METHODS:Using the inclusion criteria of micrognathia, cleft pal...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/02-055

    authors: Printzlau A,Andersen M

    更新日期:2004-01-01 00:00:00

  • Orthognathic Correction in Prader-Willi Syndrome: Occlusion and Sleep Restored.

    abstract::Children with Prader-Willi Syndrome (PWS) may present with a malocclusion and have a high propensity of developing obstructive sleep apnea (OSA). Obstructive sleep apnea is associated with short- and long-term adverse effects that negatively impact children with PWS. A case of a 15-year-old male with PWS, OSA, and a d...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1177/1055665618775724

    authors: Xiao KK,Tomur S,Beckerman R,Cassidy K,Lypka M

    更新日期:2019-03-01 00:00:00

  • Role of facial artery musculomucosal flap in large and recurrent palatal fistulae.

    abstract::Objective : Palatal fistulas are not uncommon after palatoplasty. Although there are currently many techniques that can be used to close large palatal fistulae, most of these procedures are usually cumbersome and mostly unreliable with high recurrence rates. The facial artery musculomucosal (FAMM) flap was described t...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/12-115

    authors: Shetty R,Lamba S,Gupta AK

    更新日期:2013-11-01 00:00:00

  • Complications and solutions in presurgical nasoalveolar molding therapy.

    abstract:OBJECTIVE:To outline three main categories of nasoalveolar molding complications, describe their etiologies and manifestations, and prescribe preventive and palliative therapy for their proper management. Estimates of the incidence of each complication also are provided. MATERIALS AND METHODS:Data were collected retro...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/07-236.1

    authors: Levy-Bercowski D,Abreu A,DeLeon E,Looney S,Stockstill J,Weiler M,Santiago PE

    更新日期:2009-09-01 00:00:00

  • Sutureless skin closure for cleft lip repair.

    abstract:OBJECTIVE:To study the quality of scars following the use of butyl cyanoacrylate to close the skin during cleft lip repair. DESIGN:Nonrandomized prospective study. SETTING:Tertiary care hospital. PATIENTS:Patients (n = 104) with cleft lip and palate in combination of various degrees of cleft with the age group rangi...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/05-171

    authors: Mourougayan V

    更新日期:2006-11-01 00:00:00

  • Impact of Virtual Planning on Surgical Reposition of the Premaxilla Using an Endonasal Approach and Simultaneous Alveoloplasty.

    abstract:OBJECTIVE:Describe the surgical repositioning of the premaxilla using an innovative minimally invasive endonasal approach and secondary bone graft at the same time. We want to emphasize the importance of virtual surgical planning in this technique. MATERIAL AND METHODS:A total of 6 patients with bilateral complete cle...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1177/1055665618791706

    authors: Martínez Plaza A,Martínez EB,Tara MPP,Fernandez ABM,Iglesias FM,López AE

    更新日期:2019-04-01 00:00:00

  • Effect of premature sagittal suture closure on craniofacial morphology in a prehistoric male Hopi.

    abstract::Scaphocephaly is caused by premature sagittal suture closure. It restricts medial-lateral growth of the cranial vault which appears longer and narrower than normal. We examined how this natural malformation affected morphology of the cranial base and face. A prehistoric adult male Hopi with scaphocephaly was compared ...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 历史文章,杂志文章

    doi:10.1597/1545-1569_1994_031_0385_eopssc_2.3.co_2

    authors: Kohn LA,Vannier MW,Marsh JL,Cheverud JM

    更新日期:1994-09-01 00:00:00

  • Starting a Family: The Experience of Parents With Cleft Lip and/or Palate.

    abstract:BACKGROUND:One of the key challenges facing young adults with cleft lip and/or palate is making decisions about starting a family, because there is an increased likelihood of their own child being diagnosed with cleft lip and/or palate. Should this occur, a second key challenge is how to deal with their child's diagnos...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/13-314

    authors: Stock NM,Rumsey N

    更新日期:2015-07-01 00:00:00

  • Early two-stage palatoplasty using modified Furlow's veloplasty.

    abstract:OBJECTIVE:To achieve sufficient velopharyngeal function and maxillary growth for patients with unilateral cleft lip and palate (UCLP), the authors have designed a new treatment protocol for palate closure involving early two-stage palatoplasty with modified Furlow veloplasty. Details of the surgical protocol and the ou...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/08-067.1

    authors: Nishio J,Yamanishi T,Kohara H,Hirano Y,Sako M,Adachi T,Mukai T,Miya S

    更新日期:2010-01-01 00:00:00

  • Periosteum in regeneration of palatal defects.

    abstract::The influence of the periosteum on the regeneration of palatal bone was investigated in this study. Eighty, 8-week-old, purebred beagle dogs were assigned randomly to four groups: (1) unoperated dogs as a group control; dogs in which the mid-third of the palate was surgically removed and (2) left unrepaired (unrepaire...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_1995_032_0228_piropd_2.3.co_2

    authors: Dixit UB,Kelly KM,Squier CA,Bardach J

    更新日期:1995-05-01 00:00:00

  • Early maxillary orthopedics in a child with an oblique facial cleft.

    abstract:OBJECTIVE:Oblique facial clefts are extremely rare. In view of their variability, surgical treatment cannot be standardized. To date, early maxillary orthopedics in the treatment of oblique facial clefts have not been reported. The case described here presents a newborn child with a Tessier 3 cleft. Because of the enor...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/1545-1569_1997_034_0147_emoiac_2.3.co_2

    authors: Stellzig A,Basdra EK,Mühling J,Komposch G

    更新日期:1997-03-01 00:00:00

  • Verification of speech spectrum audibility for pediatric Baha Softband users with craniofacial anomalies.

    abstract:OBJECTIVE:The purpose of this study was (1) to determine benefit of the Baha Softband coupled to the Softband for infants and children with bilateral conductive hearing loss; and (2) to verify audibility of the speech spectrum for octave frequencies 500 through 4000 Hz. DESIGN:The research design for this retrospectiv...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/08-178

    authors: Nicholson N,Christensen L,Dornhoffer J,Martin P,Smith-Olinde L

    更新日期:2011-01-01 00:00:00

  • Dental caries in the primary dentition of german children with cleft lip, alveolus, and palate.

    abstract::Objective : The purpose of this cross-sectional study was to assess the prevalence of dental caries in children with cleft lip, alveolus, and/or cleft palate living in central Germany between 1996 and 2010. Participants : A total of 295 children 1 to 6 years of age from three birth cohorts (BC) with clefts from centra...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/12-106

    authors: Kirchberg A,Makuch A,Hemprich A,Hirsch C

    更新日期:2014-05-01 00:00:00

  • Dental maturation in children with shunt-treated hydrocephalus.

    abstract:OBJECTIVE:The aim of this study was to examine the relationship between dental maturation and somatic development and to discover their possible deviations in children with shunt-treated hydrocephalus. DESIGN:Radiographs (orthopantomogram and hand-wrist radiograph) from children with shunt-treated hydrocephalus were a...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/03-018.1

    authors: Pirttiniemi P,Poikela A,Huggare J,Löppönen T

    更新日期:2004-11-01 00:00:00

  • Development of a microportable imaging system for otoscopy and nasoendoscopy evaluations.

    abstract:OBJECTIVE:Imaging systems for patients with cleft palate typically are not portable, but are essential to obtain an audiovisual record of nasoendoscopy and otoscopy procedures. Practitioners who evaluate patients in rural, remote, or otherwise medically underserved areas are expected to obtain audiovisual recordings of...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/05-063.1

    authors: VanLue M,Cox KM,Wade JM,Tapp K,Linville R,Cosmato C,Smith T

    更新日期:2007-03-01 00:00:00

  • Management of alveolar cleft bone grafting--state of the art.

    abstract::Bone grafting of the alveolus is an essential step in the reconstruction of the orofacial cleft deformity. Secondary grafting with iliac marrow consistently produces trabecular bone to unify the maxilla and provide odontogenic support. It requires preoperative maxillary alignment, well designed mucoperiosteal flaps, a...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章,评审

    doi:10.1597/1545-1569_2000_037_0229_moacbg_2.3.co_2

    authors: Eppley BL,Sadove AM

    更新日期:2000-05-01 00:00:00

  • Cone Beam Computed Tomography Analysis of Oropharyngeal Airway in Preadolescent Nonsyndromic Bilateral and Unilateral Cleft Lip and Palate Patients.

    abstract:OBJECTIVE:The objective of this study was to assess the volume, area, and dimensions of the oropharyngeal airway (OPA) in a previously repaired nonsyndromic unilateral cleft lip and palate (UCLP) versus bilateral cleft lip and palate (BCLP) patients when compared with noncleft controls using cone beam computed tomograp...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/15-322

    authors: Al-Fahdawi MA,El-Kassaby MA,Farid MM,El-Fotouh MA

    更新日期:2018-07-01 00:00:00

  • Incidence of cleft lip and palate in Uganda.

    abstract:OBJECTIVE:The purpose of the study was to estimate the need for resources for cleft repairs in Uganda by determining the overall incidence of oral-facial clefts and the ratio of isolated cleft lip to isolated cleft palate to cleft lip and palate. DESIGN:A 1-year prospective study was implemented in seven hospitals and...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章

    doi:10.1597/09-076

    authors: Dreise M,Galiwango G,Hodges A

    更新日期:2011-03-01 00:00:00

  • Assessing intelligibility in speakers with cleft palate: a critical review of the literature.

    abstract:OBJECTIVE:A literature review was conducted in order to investigate three research questions: how is speech intelligibility being measured in speakers with cleft lip and palate? Is intelligibility adequately being distinguished from related measures such as acceptability? Has there been an increased understanding of in...

    journal_title:The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association

    pub_type: 杂志文章,meta分析

    doi:10.1597/1545-1569_2002_039_0050_aiiswc_2.0.co_2

    authors: Whitehill TL

    更新日期:2002-01-01 00:00:00