Abstract:
OBJECTIVE:To evaluate the accuracy of a deep learning-based auto-segmentation mode to that of manual contouring by one medical resident, where both entities tried to mimic the delineation "habits" of the same clinical senior physician. METHODS:This study included 125 cervical cancer patients whose clinical target volumes (CTVs) and organs at risk (OARs) were delineated by the same senior physician. Of these 125 cases, 100 were used for model training and the remaining 25 for model testing. In addition, the medical resident instructed by the senior physician for approximately 8 months delineated the CTVs and OARs for the testing cases. The dice similarity coefficient (DSC) and the Hausdorff Distance (HD) were used to evaluate the delineation accuracy for CTV, bladder, rectum, small intestine, femoral-head-left, and femoral-head-right. RESULTS:The DSC values of the auto-segmentation model and manual contouring by the resident were, respectively, 0.86 and 0.83 for the CTV (P < 0.05), 0.91 and 0.91 for the bladder (P > 0.05), 0.88 and 0.84 for the femoral-head-right (P < 0.05), 0.88 and 0.84 for the femoral-head-left (P < 0.05), 0.86 and 0.81 for the small intestine (P < 0.05), and 0.81 and 0.84 for the rectum (P > 0.05). The HD (mm) values were, respectively, 14.84 and 18.37 for the CTV (P < 0.05), 7.82 and 7.63 for the bladder (P > 0.05), 6.18 and 6.75 for the femoral-head-right (P > 0.05), 6.17 and 6.31 for the femoral-head-left (P > 0.05), 22.21 and 26.70 for the small intestine (P > 0.05), and 7.04 and 6.13 for the rectum (P > 0.05). The auto-segmentation model took approximately 2 min to delineate the CTV and OARs while the resident took approximately 90 min to complete the same task. CONCLUSION:The auto-segmentation model was as accurate as the medical resident but with much better efficiency in this study. Furthermore, the auto-segmentation approach offers additional perceivable advantages of being consistent and ever improving when compared with manual approaches.
journal_name
J Appl Clin Med Physjournal_title
Journal of applied clinical medical physicsauthors
Wang Z,Chang Y,Peng Z,Lv Y,Shi W,Wang F,Pei X,Xu XGdoi
10.1002/acm2.13097subject
Has Abstractpub_date
2020-12-01 00:00:00pages
272-279issue
12issn
1526-9914journal_volume
21pub_type
杂志文章abstract:PURPOSE:The objective of this study was to evaluate the impact of the magnetic field regulation in conjunction with the volumetric repainting technique on the spot positions and range in pencil beam scanning proton therapy. METHODS:"Field regulation" - a feature to reduce the switching time between layers by applying ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.13045
更新日期:2020-10-15 00:00:00
abstract:PURPOSE:Segmentation of liver organ and tumors from computed tomography (CT) scans is an important task for hepatic surgical planning. Manual segmentation of liver and tumors is tedious, time-consuming, and biased to the clinician experience. Therefore, automatic segmentation of liver and tumors is highly desirable. It...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00
abstract::In this project, we investigated the use of an electronic portal imaging device (EPID), together with the treatment planning system (TPS) and MLC log files, to determine the delivered doses to the patient and evaluate the agreement between the treatment plan and the delivered dose distribution. The QA analysis results...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i3.5283
更新日期:2015-05-08 00:00:00
abstract::The use of solid carbon fiber table materials in radiotherapy has become more common with the implementation of image-guided radiotherapy (IGRT), since the solid materials give less imaging artifacts than the so-called tennis racket couchtops. The downside of the solid carbon fiber couch inserts is that they increase ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v12i4.3554
更新日期:2011-11-15 00:00:00
abstract::Varian (Palo Alto, California, United States) recently released an online adaptation treatment platform, Ethos, which has introduced a new Dose Preview and Automated Plan Generation module despite sharing identical beam data with the existing Halcyon linac. The module incorporates a preconfigured beam model and the Ac...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2020-12-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v13i6.3981
更新日期:2012-11-08 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
abstract:PURPOSE:To provide insight into the types of questions asked to medical physicists by patients during one-on-one physicist-patient consults at one institution. MATERIALS AND METHODS:Medical physicists trained in patient communication techniques met with patients to provide an overview of the treatment planning and del...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12942
更新日期:2020-08-01 00:00:00
abstract::The nonphysical wedge is a modality that uses computer-controlled jaw motion to generate wedge-shaped dose distributions. There are Varian enhanced dynamic wedges (EDWs) and Siemens virtual wedges (VWs). We recently commissioned dynamic wedges on both Varian and Siemens LINACs. The beam data, acquired with a Wellhofer...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2004-10-01 00:00:00
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2010-10-13 00:00:00
abstract::External beam radiation therapy (RT) is often offered to breast cancer patients after surgical mastectomy followed by breast reconstruction with silicone implants. In some cases, the RT is administered while the patient is still implanted with a temporary tissue expander including a high-density metallic port, which i...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v12i2.3295
更新日期:2011-01-19 00:00:00
abstract::The dosimetry of very small electron fields can be challenging due to relative shifts in percent depth-dose curves, including the location of dmax, and lack of lateral electronic equilibrium in an ion chamber when placed in the beam. Conventionally a small parallel plate chamber or film is utilized to perform small fi...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v12i1.3267
更新日期:2010-10-04 00:00:00
abstract::The purpose of this investigation is to measure, characterize and report stray photon leakage and scatter radiation measurements from the Mobetron, an intraoperative electron linear accelerator designed for use in an operating room environment. The study is needed due to recent changes to the shielding design of the M...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v11i4.3151
更新日期:2010-09-07 00:00:00
abstract::Substantial disagreement exists over appropriate PET segmentation techniques for non-small cell lung cancer. Currently, no segmentation algorithm explicitly considers tumor motion in determining tumor borders. We developed an automatic PET segmentation model as a function of target volume, motion extent, and source-to...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v15i1.4600
更新日期:2014-01-06 00:00:00
abstract::Locally advanced non-small-cell lung cancer (NSCLC) is a common disease with a low overall survival even with aggressive treatments. Standard imaging (CT and PET/CT) provide no information about normal lung function. We therefore, sought to pilot HeMRI in patients with non-small-cell lung cancer before and after defin...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v12i2.3357
更新日期:2011-01-31 00:00:00
abstract:INTRODUCTION:Increased modulation and dynamical delivery of external beam radiotherapy (EBRT), such as volumetric modulated arc therapy (VMAT) with dynamic gantry rotation, continuously variable dose rate (CVDR) and field shapes that change during the beam, place greater demands on the performance of linear accelerator...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.13047
更新日期:2020-10-23 00:00:00
abstract::Measurement of cumulative dose ƒ(0,150) with a small ionization chamber within standard polymethyl methacrylate (PMMA) CT head and body phantoms, 150 mm in length, is a possible practical method for cone-beam computed tomography (CBCT) dosimetry. This differs from evaluating cumulative dose under scatter equilibrium c...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i6.5793
更新日期:2015-11-08 00:00:00
abstract:PURPOSE:We introduce a technique that employs a 2D detector in transmission mode (TM) to verify dose maps at a depth of dmax in Solid Water. TM measurements, when taken at a different surface-to-detector distance (SDD), allow for the area at dmax (in which the dose map is calculated) to be adjusted. METHODS:We conside...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12744
更新日期:2019-11-01 00:00:00
abstract::Radiographic film dosimetry provides fast, convenient 2-D dose distributions, but is challenged by the dependence of film response on scatter conditions (i.e., energy dependence). Verification of delivered dose in the surface buildup region is important for intensity modulated radiation therapy (IMRT) when volumes of ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v9i4.2782
更新日期:2008-10-24 00:00:00
abstract::Treatment planning for breast cancer has been traditionally based on clinical landmarks. The Radiation Therapy Oncology Group (RTOG) published consensus guidelines on contouring target volumes (TV) for the breast/chest wall and draining lymphatics. The effect of these guidelines on dosimetric parameters in surrounding...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v15i2.4547
更新日期:2014-03-06 00:00:00
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journal_title:Journal of applied clinical medical physics
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更新日期:2016-09-08 00:00:00
abstract:PURPOSE:The target detectability of cone beam computed tomography (CBCT) performed in image-guided radiation therapy (IGRT) was investigated to achieve sufficient image quality for patient positioning over a course of treatment session while maintaining radiation exposure from CBCT imaging as low as reasonably achievab...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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更新日期:2018-05-01 00:00:00
abstract::Part II of this review article presents four case studies for which peak skin doses are calculated following the methods outlined in Part I of this review. The data available in the cases ranges from proprietary dose reports to fluoroscopy time and number of digital acquisition frames only. Flowcharts are provided for...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v13i1.3693
更新日期:2012-01-05 00:00:00
abstract::Intraoperative electron radiation therapy (IOERT) cannot usually benefit, as conventional external radiotherapy, from software systems of treatment planning based on computed tomography and from common dose verify procedures. For this reason, in vivo film dosimetry (IVFD) proves to be an effective methodology to evalu...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i1.5065
更新日期:2014-01-08 00:00:00
abstract::The purpose of this study is to evaluate the accuracy of the electron Monte Carlo (eMC) dose calculation algorithm included in a commercial treatment planning system and compare its performance against an electron pencil beam algorithm. Several tests were performed to explore the system's behavior in simple geometries...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v16i3.4636
更新日期:2015-05-08 00:00:00
abstract::The case of a 50-year-old man affected by a rhabdomiosarcoma metastatic lesion in the left flank Is reported. The patient was addressed to 50.4 Gy radiotherapy with concomitant chemotherapy in order to locally control the lesion. A Tri-60-Co magnetic resonance hybrid radiotherapy unit was used for treatment delivery a...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12575
更新日期:2019-06-01 00:00:00
abstract::The goal of the present study was to develop a new dose-volume histogram (DVH)- based homogeneity index for effectively evaluating the dose homogeneity of intensity-modulated radiotherapy plans. The new index, called the sigma-index ("S-index") is defined as the standard deviation of the normalized differential DVH cu...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v8i2.2390
更新日期:2007-03-20 00:00:00
abstract:PURPOSE:Prescription practice in SRS plans for brain tumors differs significantly for different modalities. In this retrospective study, the strategies to optimize SRS plans for brain tumors with volumetric arc therapy (VMAT) were presented. METHODS:Fifty clinically treated cases were stratified by the maximum target ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12818
更新日期:2020-03-01 00:00:00
abstract::A patient specific quality assurance (QA) should detect errors that originate anywhere in the treatment planning process. However, the increasing complexity of treatment plans has increased the need for improvements in the accuracy of the patient specific pretreatment verification process. This has led to the utilizat...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.12114
更新日期:2017-07-01 00:00:00
abstract::Independent treatment planning system (TPS) check with Mobius3D software, log files based quality assurance (QA) with MobiusFX, and phantom measurement-based QA with ArcCHECK were performed and cross verified for head-and-neck (17 patients), chest (16 patients), and abdominal (19 patients) cancer patients who underwen...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1002/acm2.13036
更新日期:2020-10-01 00:00:00