Transatlantic Lipid Guideline Divergence: Same Data But Different Interpretations.

abstract：:Background The purpose of this study was to determine whether the presence of antegrade blood flow was related to stroke subtype in patients with acute intracranial large artery occlusion. Methods and Results The prospectively collected data for consecutive patients who had occlusion of the unilateral M1 segment of th...

journal_title：Journal of the American Heart Association

authors： Zhang M,Chen Z,Xu J,Gong X,Shi F,Lou M

更新日期：2020-10-20 00:00:00

abstract：BACKGROUND:Left ventricular noncompaction (LVNC) has since been classified as a primary genetic cardiomyopathy, but the genetic basis is not fully evaluated. The aim of the present study was to identify the genetic spectrum using next-generation sequencing and to evaluate genotype-phenotype correlations in LVNC patient...

journal_title：Journal of the American Heart Association

authors： Wang C,Hata Y,Hirono K,Takasaki A,Ozawa SW,Nakaoka H,Saito K,Miyao N,Okabe M,Ibuki K,Nishida N,Origasa H,Yu X,Bowles NE,Ichida F,for LVNC Study Collaborators.

更新日期：2017-08-30 00:00:00

abstract：:Background We examined the prevalence of high burdens and barriers to care among adults with heart disease treatment. Methods and Results The participants were aged 18 to 64 years from the Medical Expenditure Panel Survey-Household Component (MEPS-HC) for 2010-2015. High burden is out-of-pocket spending on care and in...

journal_title：Journal of the American Heart Association

authors： Bernard D,Fang Z

更新日期：2019-12-17 00:00:00

abstract：:Background Hyperkalemia has been associated with increased mortality in patients with myocardial infarction, but few data exist regarding hyperkalemia in cardiac intensive care unit ( CICU ) patients. We hypothesize that hyperkalemia is associated with increased mortality in unselected CICU patients. Methods and Resul...

journal_title：Journal of the American Heart Association

authors： Brueske B,Sidhu MS,Schulman-Marcus J,Kashani KB,Barsness GW,Jentzer JC

更新日期：2019-04-02 00:00:00

abstract：:Background Reduced miR-133a was previously found to be associated with thoracic aortic ( TA ) dilation, as seen in aneurysm disease. Because wall tension increases with vessel diameter (Law of Laplace), this study tested the hypothesis that elevated tension led to the reduction of miR-133a in the TA . Methods and Resu...

journal_title：Journal of the American Heart Association

authors： Akerman AW,Blanding WM,Stroud RE,Nadeau EK,Mukherjee R,Ruddy JM,Zile MR,Ikonomidis JS,Jones JA

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:Intramyocardial injection of mesenchymal stem cells (MSCs) in chronic ischemic cardiomyopathy is associated with reverse remodeling in experimental models and humans. Here, we tested the hypothesis that allogeneic MSC therapy drives ventricular remodeling by producing durable and progressive scar size reduct...

journal_title：Journal of the American Heart Association

authors： Williams AR,Suncion VY,McCall F,Guerra D,Mather J,Zambrano JP,Heldman AW,Hare JM

更新日期：2013-05-17 00:00:00

abstract：BACKGROUND:Currently, acute ischemic stroke is still a leading cause of mortality and morbidity. Approximately 2 years ago, mechanical thrombectomy was proven beneficial as a revolutionary new therapy for stroke in the MR-CLEAN trial (A Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic ...

journal_title：Journal of the American Heart Association

authors： Autar ASA,Hund HM,Ramlal SA,Hansen D,Lycklama À Nijeholt GJ,Emmer BJ,de Maat MPM,Dippel DWJ,van der Lugt A,van Es ACGM,van Beusekom HMM,MR CLEAN Registry Investigators.

更新日期：2018-06-22 00:00:00

abstract：BACKGROUND:Remote ischemic conditioning (RIC) is a noninvasive therapeutic strategy that uses brief cycles of blood pressure cuff inflation and deflation to protect the myocardium against ischemia-reperfusion injury. The objective of this systematic review was to determine the impact of RIC on myocardial salvage index,...

journal_title：Journal of the American Heart Association

authors： McLeod SL,Iansavichene A,Cheskes S

更新日期：2017-05-17 00:00:00

abstract：BACKGROUND:Although guidelines for antiarrhythmic drug therapy in atrial fibrillation (AF) were published in 2006, it remains uncertain whether adherence to these guidelines affects patient outcomes. METHODS AND RESULTS:We retrospectively evaluated the records of 5976 consecutive AF patients who were prescribed at lea...

journal_title：Journal of the American Heart Association

authors： Qin D,Leef G,Alam MB,Rattan R,Munir MB,Patel D,Khattak F,Vaghasia N,Adelstein E,Jain SK,Saba S

更新日期：2015-04-06 00:00:00

abstract：:Background Sepsis is the overwhelming host response to infection leading to shock and multiple organ dysfunction. Cardiovascular complications greatly increase sepsis-associated mortality. Although murine models are routinely used for preclinical studies, the benefit of using genetically engineered mice in sepsis is c...

journal_title：Journal of the American Heart Association

authors： Hoffman M,Kyriazis ID,Lucchese AM,de Lucia C,Piedepalumbo M,Bauer M,Schulze PC,Bonios MJ,Koch WJ,Drosatos K

更新日期：2019-05-21 00:00:00

abstract：:The coronavirus disease 2019 pandemic, caused by severe acute respiratory syndrome coronavirus-2, represents the third human affliction attributed to the highly pathogenic coronavirus in the current century. Because of its highly contagious nature and unprecedented global spread, its aggressive clinical presentation, ...

journal_title：Journal of the American Heart Association

authors： Patel V,Jimenez E,Cornwell L,Tran T,Paniagua D,Denktas AE,Chou A,Hankins SJ,Bozkurt B,Rosengart TK,Jneid H

更新日期：2020-07-07 00:00:00

abstract：:Background The incidence of conduction abnormalities requiring permanent pacemaker implantation (PPI) after transcatheter aortic valve replacement (TAVR) with early and later generation prostheses remains debated. Methods and Results Based on the administrative hospital-discharge database, we collected information for...

journal_title：Journal of the American Heart Association

authors： Bisson A,Bodin A,Herbert J,Lacour T,Saint Etienne C,Pierre B,Clementy N,Deharo P,Babuty D,Fauchier L

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:The geometric organization of myocytes in the ventricular wall comprises the structural underpinnings of cardiac mechanical function. Cardiac myosin binding protein-C (MYBPC3) is a sarcomeric protein, for which phosphorylation modulates myofilament binding, sarcomere morphology, and myocyte alignment in the ...

journal_title：Journal of the American Heart Association

authors： Taylor EN,Hoffman MP,Barefield DY,Aninwene GE 2nd,Abrishamchi AD,Lynch TL 4th,Govindan S,Osinska H,Robbins J,Sadayappan S,Gilbert RJ

更新日期：2016-03-15 00:00:00

abstract：BACKGROUND:Elevated albuminuria as well as an increased serum uric acid concentration is associated with poor cardiovascular outcome. We questioned whether these 2 variables (albuminuria and serum uric concentration) may be interrelated via tubular uric acid reabsorption. METHODS AND RESULTS:Included were 7688 partici...

journal_title：Journal of the American Heart Association

authors： Scheven L,Joosten MM,de Jong PE,Bakker SJ,Gansevoort RT,PREVEND study group.

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is a major risk factor for the development of chronic kidney disease. Nuclear factor-κB is a nuclear transcription factor activated post-ischemia, responsible for the transcription of proinflammatory proteins. The role of nuclear factor-κB in the renal fibrosis post-AKI is unknown. ...

journal_title：Journal of the American Heart Association

authors： Johnson FL,Patel NSA,Purvis GSD,Chiazza F,Chen J,Sordi R,Hache G,Merezhko VV,Collino M,Yaqoob MM,Thiemermann C

更新日期：2017-07-03 00:00:00

abstract：BACKGROUND:Sedentary behaviors have been directly associated with all-cause mortality. However, little is known about different types of sedentary behaviors in relation to overall mortality. Our objective was to assess the association between different sedentary behaviors and all-cause mortality. METHODS AND RESULTS:I...

journal_title：Journal of the American Heart Association

authors： Basterra-Gortari FJ,Bes-Rastrollo M,Gea A,Núñez-Córdoba JM,Toledo E,Martínez-González MÁ

更新日期：2014-06-25 00:00:00

abstract：:Background Coronary artery disease is the primary etiology for sudden cardiac arrest in adults, but potential differences in the incidence and utility of invasive coronary testing between resuscitated men and women have not been extensively evaluated. Our aim was to characterize angiographic similarities and differenc...

journal_title：Journal of the American Heart Association

authors： May T,Skinner K,Unger B,Mooney M,Patel N,Dupont A,McPherson J,McMullan P,Nielsen N,Seder DB,Kern KB

更新日期：2020-04-07 00:00:00

abstract：BACKGROUND:The structure of the aorta is considered to influence exercise systolic blood pressure (SBP) response, which, in turn, might impact upon adverse outcomes. The current study sought to investigate the relationship of aortic calcification and exercise SBP with adverse outcomes among elderly individuals. METHOD...

journal_title：Journal of the American Heart Association

authors： Cho IJ,Chang HJ,Cho I,Heo R,Lee SE,Shim CY,Hong GR,Chung N

更新日期：2016-04-22 00:00:00

abstract：:Background Recently, direct oral anticoagulants have been introduced for venous thromboembolism (VTE), which might change the management strategies of VTE. However, there have been limited data on the current real-world practice pattern for VTE in Asian countries. Methods and Results The JROAD-DPC (Japanese Registry o...

journal_title：Journal of the American Heart Association

authors： Yamashita Y,Morimoto T,Yoshikawa Y,Yaku H,Sumita Y,Nakai M,Ono K,Kimura T

更新日期：2020-01-21 00:00:00

abstract：:Background We examined temporal trends, timing, and frequency, as well as adverse neonatal and maternal outcomes occurring in the first year postpartum among women experiencing syncope during pregnancy. Methods and Results This was a retrospective study of pregnancies between January 1, 2005, and December 31, 2014, in...

journal_title：Journal of the American Heart Association

authors： Chatur S,Islam S,Moore LE,Sandhu RK,Sheldon RS,Kaul P

更新日期：2019-05-21 00:00:00

abstract：:Background It has been suggested that endocardial and epicardial ablation of ventricular tachycardia ( VT ) improves outcome in arrhythmogenic right ventricular cardiomyopathy/dysplasia. We investigated our sequential approach for VT ablation in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia i...

journal_title：Journal of the American Heart Association

authors： Mathew S,Saguner AM,Schenker N,Kaiser L,Zhang P,Yashuiro Y,Lemes C,Fink T,Maurer T,Santoro F,Wohlmuth P,Reißmann B,Heeger CH,Tilz R,Wissner E,Rillig A,Metzner A,Kuck KH,Ouyang F

更新日期：2019-03-05 00:00:00

abstract：BACKGROUND:The natural history of coronary artery aneurysms (CAA) after intravenous immunoglobulin (IVIG) treatment in the United States is not well described. We describe the natural history of CAA in US Kawasaki disease (KD) patients and identify factors associated with major adverse cardiac events (MACE) and CAA reg...

journal_title：Journal of the American Heart Association

authors： Friedman KG,Gauvreau K,Hamaoka-Okamoto A,Tang A,Berry E,Tremoulet AH,Mahavadi VS,Baker A,deFerranti SD,Fulton DR,Burns JC,Newburger JW

更新日期：2016-09-15 00:00:00

abstract：:Background Tetrahydrobiopterin is a cofactor of endothelial NO synthase ( eNOS ), which is critical to embryonic heart development. We aimed to study the effects of sapropterin (Kuvan), an orally active synthetic form of tetrahydrobiopterin on eNOS uncoupling and congenital heart defects ( CHD s) induced by pregestati...

journal_title：Journal of the American Heart Association

authors： Engineer A,Saiyin T,Lu X,Kucey AS,Urquhart BL,Drysdale TA,Norozi K,Feng Q

更新日期：2018-11-06 00:00:00

abstract：BACKGROUND:There is accumulating evidence that serum levels of non-high-density lipoprotein cholesterol (non-HDL-C) are a more accurate predictor of cardiovascular outcomes when compared with low-density lipoprotein cholesterol. However, we recently found that higher serum concentrations of triglycerides are associated...

journal_title：Journal of the American Heart Association

authors： Chang TI,Streja E,Ko GJ,Naderi N,Rhee CM,Kovesdy CP,Kashyap ML,Vaziri ND,Kalantar-Zadeh K,Moradi H

更新日期：2018-06-09 00:00:00

abstract：:Background Endovascular repair has become a viable alternative for aortic pathological features, including those located within the aortic arch. We investigated the anatomic suitability for branched thoracic endovascular repair in patients previously treated with conventional open surgery for aortic arch pathological ...

journal_title：Journal of the American Heart Association

authors： Smorenburg SPM,Montesano M,Hoogteijling TJ,Truijers M,Symersky P,Jansen EK,Zandbergen HR,Wisselink W,van Schaik TG,Yeung KK

更新日期：2020-10-20 00:00:00

abstract：:Background Antazoline mesylate represents an antihistamine capable of rapid and safe cardioversion of atrial fibrillation, yet evidence concerning its efficacy in comparison to other medications is insufficient. The study aimed to evaluate the success rate and safety of pharmacological cardioversion of atrial fibrilla...

journal_title：Journal of the American Heart Association

authors： Wybraniec MT,Wróbel W,Wilkosz K,Wrona K,Bula K,Mizia-Stec K

更新日期：2018-10-16 00:00:00

abstract：BACKGROUND:Carotid atherosclerosis (CA) is a reflector of generalized atherosclerosis that is associated with systemic vascular disease. Data are limited on the epidemiology of carotid lesions in a large, nationally representative population sample. We aimed to evaluate the prevalence of CA detected by carotid ultrason...

journal_title：Journal of the American Heart Association

authors： Wang X,Li W,Song F,Wang L,Fu Q,Cao S,Gan Y,Zhang W,Yue W,Yan F,Shi W,Wang X,Zhang H,Zhang H,Wang Z,Lu Z

更新日期：2018-04-05 00:00:00

abstract：:Background Systemic innate immune priming is a recognized sequela of post-ischemic neuroinflammation and contributor to delayed neurodegeneration. Given mounting evidence linking acute stroke with reactive lung inflammation, we asked whether enhanced expression of the endogenous antioxidant extracellular superoxide di...

journal_title：Journal of the American Heart Association

authors： Mai N,Miller-Rhodes K,Prifti V,Kim M,O'Reilly MA,Halterman MW

更新日期：2019-05-07 00:00:00

abstract：BACKGROUND:A cohort study found that 9/11-related environmental exposures and posttraumatic stress disorder increased self-reported cardiovascular disease risk. We attempted to replicate these findings using objectively defined cardiovascular disease hospitalizations in the same cohort. METHODS AND RESULTS:Data for ad...

journal_title：Journal of the American Heart Association

authors： Jordan HT,Stellman SD,Morabia A,Miller-Archie SA,Alper H,Laskaris Z,Brackbill RM,Cone JE

更新日期：2013-10-24 00:00:00

abstract：BACKGROUND:Cardiovascular disease is the leading cause of death in the United States, making improving cardiovascular health a key population health goal. As part of efforts to achieve this, the American Heart Association has developed the first comprehensive cardiovascular health index (CVHI). Our objective was to inv...

journal_title：Journal of the American Heart Association

authors： Pilkerton CS,Singh SS,Bias TK,Frisbee SJ

更新日期：2015-09-22 00:00:00