Abstract:
:Restless legs syndrome (RLS) is highly prevalent among pregnant women. In the present study, a neurological-obstetrical sample of 561 postpartum women was retrospectively screened for RLS symptoms during pregnancy and in the first 12 weeks postpartum. The first screening took place within 1 to 6 days of delivery (T0) and the second 12 weeks after childbirth (T1). The pregnancy-related RLS prevalence rate was found to be 21% (n = 119), with the women suffering from RLS being more often affected by psychiatric history and having been more exposed to stressful life events. They were also found to have experienced baby blues more frequently shortly after childbirth. However, RLS in pregnancy did not appear to have any effect on the development of postpartum depression. Additionally, a positive trend was observed toward an association between pregnancy-related RLS and gestational diabetes and hypertension. Of the 119 women, 23 (19.3%) remained affected by RLS 12 weeks postpartum. Body mass index (BMI), weight gain, parity, childbearing history, or chronic stress exposure in pregnancy as measured by hair cortisol were not found to be linked to RLS. In summary, a comprehensive understanding of the interaction of clinical, environmental, and anamnestic factors can help shed valuable light on this pregnancy-related condition.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Goecke TW,Schnakenberg P,Frensch M,Chechko Ndoi
10.3390/jcm9093046subject
Has Abstractpub_date
2020-09-21 00:00:00issue
9issn
2077-0383pii
jcm9093046journal_volume
9pub_type
杂志文章abstract:BACKGROUND:Heart failure with preserved ejection fraction (HFpEF) remains an ongoing therapeutic and diagnostic challenge to date. In this study we aimed for an analysis of the diagnostic potential of four novel cardiovascular biomarkers, GDF-15, H-FABP, sST2, and suPAR in HFpEF patients compared to controls as well as...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9041130
更新日期:2020-04-15 00:00:00
abstract::Coronavirus disease 2019 (COVID-19) is a pandemic viral disease originated in Wuhan, China, in December 2019, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The severe form of the disease is often associated with acute respiratory distress syndrome (ARDS), and most critically ill patients ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
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更新日期:2020-08-26 00:00:00
abstract::We aimed to test the association between low-density lipoprotein cholesterol (LDL-C) and cardiovascular disease (CVD), cancer, and all-cause mortality in non-statin users. A total of 347,971 subjects in Kangbuk Samsung Health Study (KSHS.57.4% men, mean follow up: 5.64 ± 3.27 years) were tested. To validate these asso...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8101571
更新日期:2019-10-01 00:00:00
abstract::Overactivated osteoclasts lead to many bone diseases, including osteoporosis and rheumatoid arthritis. The p38 MAPK (p38) is an essential regulator of the receptor activator of nuclear factor-κB ligand (RANKL)-mediated osteoclastogenesis and bone loss. We previously reported TAT conjugated thioredoxin-interacting prot...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8040431
更新日期:2019-03-29 00:00:00
abstract::Diabetic foot ulcers (DFUs) and diabetic foot infections (DFIs) are associated with reduced patient quality of life, lower-extremity amputation, hospitalization, and high morbidity and mortality. Diverse bacterial communities have been identified in DFUs/DFIs, playing a significant role in infection prognosis. However...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
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更新日期:2019-11-10 00:00:00
abstract::Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder, with the characteristic symptoms of chronic abdominal pain and altered bowel habits (diarrhea, constipation, or both). IBS is a highly prevalent condition, which negatively affects quality of life and is a significant burden on global healthcare...
journal_title:Journal of clinical medicine
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更新日期:2017-11-03 00:00:00
abstract::Sepsis is a major cause of death in intensive care units worldwide. The acute phase of sepsis is often accompanied by sepsis-associated encephalopathy, which is highly associated with increased mortality. Moreover, in the chronic phase, more than 50% of surviving patients suffer from severe and long-term cognitive def...
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pub_type: 杂志文章,评审
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更新日期:2020-03-05 00:00:00
abstract::Novel strategies are needed to address vaccine hesitancy (VH), which correlates with complementary and alternative medicine (CAM). In Switzerland, CAM providers play important roles in vaccine counseling of vaccine hesitant (VH) parents, and traditional vaccination messaging tends to overlook CAM provider perspectives...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
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更新日期:2020-02-21 00:00:00
abstract::Snail1 transcriptional factor plays a key role in the control of epithelial to mesenchymal transition and fibroblast activation. As a consequence, Snail1 expression and function is regulated at multiple levels from gene transcription to protein modifications, affecting its interaction with specific cofactors. In this ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm8060757
更新日期:2019-05-28 00:00:00
abstract::Patient-reported outcome measures (PROMs) are used to assess satisfaction after total hip arthroplasty (THA); however, the factors that determine these PROMs remain unclear. This study aimed to identify the patient- and surgery-related factors that affect patient satisfaction after THA as indicated by the Oxford Hip S...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm7100358
更新日期:2018-10-15 00:00:00
abstract::Microbial contamination could compromise the stability of dental implants increasing the risk of inflammatory reactions in the surrounding soft tissues. In this human, randomized, double-blind, clinical study, the presence of Porphyromonas gingivalis on the healing abutment and the inflammatory infiltrate surrounding ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9010284
更新日期:2020-01-20 00:00:00
abstract::Multidisciplinary interventions have been developed for patients with atopic dermatitis (AD) and their families, with the aim of improving outcomes such as disease control, adherence, and quality of life. We reviewed the content of different multidisciplinary approaches to intervention for AD and evidence for their im...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm4051156
更新日期:2015-05-21 00:00:00
abstract::Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and is associated with significant morbidity and mortality. The autonomic nervous system (ANS) plays an important role in the initiation and development of AF, causing alterations in atrial structure and electrophysiological defects. The intrinsic ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9103081
更新日期:2020-09-24 00:00:00
abstract:PURPOSE:Evasion of the immune system by cancer cells allows for the progression of tumors. Antitumor immunotherapy has shown remarkable effects in a diverse range of cancers. The aim of this study was to determine the clinicopathological significance of human epidermal growth factor receptor 2 (HER2), indoleamine 2,3-d...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9051265
更新日期:2020-04-27 00:00:00
abstract::We investigated the prognostic influence of androgen receptor (AR) on breast cancer. AR status was assessed using immunohistochemistry with tissue microarrays from 395 operable primary breast cancer patients who received curative surgery. The Kaplan-Meier estimator was used to analyze the survival rates and a log-rank...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9041083
更新日期:2020-04-10 00:00:00
abstract:BACKGROUND:Cefazolin is in vitro active against wild isolates of Escherichia coli, Klebsiella species, and Proteus mirabilis (EKP), but clinical evidence supporting the contemporary susceptibility breakpoint issued by the Clinical and Laboratory Standards Institute (CLSI) are limited. METHODS:Between 2010 and 2015, ad...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9010157
更新日期:2020-01-07 00:00:00
abstract:OBJECTIVE:In order to promote physical activity (PA) in patients with complicated type 2 diabetes, a better understanding of daily movement is required. We (1) objectively assessed PA in patients with type 2 diabetes, and (2) studied the association between muscle mass, dietary protein intake, and PA. Methods: We perfo...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9103104
更新日期:2020-09-25 00:00:00
abstract::Limited data are available regarding optimal treatment for refractory Mycobacterium avium complex-pulmonary disease (MAC-PD). We evaluated outcomes of inhaled amikacin (AMK) with clofazimine (CFZ) regimens as an add-on salvage therapy for refractory MAC-PD. We retrospectively analyzed 52 patients with refractory MAC-P...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9092968
更新日期:2020-09-14 00:00:00
abstract::To define the role of spleen stiffness (SS) and liver stiffness (LS) in myelofibrosis and other Philadelphia (Ph)-negative myeloproliferative neoplasms (MPNs), we studied, by ultrasonography (US) and elastography (ES), 70 consecutive patients with myelofibrosis (MF) (no.43), essential thrombocythemia (ET) (no.10), and...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9072149
更新日期:2020-07-08 00:00:00
abstract::Examination of the corneal surface by in vivo confocal microscopy (IVCM) allows for objective identification of corneal and conjunctival cell phenotypes to evaluate different epithelialization patterns. Detection of a corneal-conjunctival epithelial transition could be considered as a sign of restored epithelial funct...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9113574
更新日期:2020-11-06 00:00:00
abstract::Intraovarian platelet-rich plasma (PRP) infusion was recently introduced in the context of addressing ovarian insufficiency. Reporting on its effectiveness prior to adopting in clinical routine practice is imperative. This study aims to provide pilot data regarding PRP application for ovarian rejuvenation. Four pilot ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9061809
更新日期:2020-06-10 00:00:00
abstract::One in every four deaths is due to cancer in Europe. In view of its increasing incidence, cancer became the leading cause of death and disease burden in Denmark, France, the Netherlands, and the UK. Without essential improvements in cancer prevention, an additional 775,000 cases of annual incidence have been prognosed...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9092749
更新日期:2020-08-25 00:00:00
abstract:INTRODUCTION:Telemedicine is believed to be helpful in managing patients suffering from chronic diseases, in particular elderly patients with numerous accompanying conditions. This was the basis for the "GERIATRICS and e-Technology (GER-e-TEC) study", which was an experiment involving the use of the smart MyPredi™ e-pl...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9123836
更新日期:2020-11-26 00:00:00
abstract:BACKGROUND:Sarcopenia is a prevalent muscle abnormality characterized by progressive and generalized loss of skeletal muscle mass and strength, common among patients with decompensated advanced chronic liver disease (dACLD). Irisin is a recently identified myokine, which is mainly expressed and secreted by skeletal mus...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9103158
更新日期:2020-09-29 00:00:00
abstract::Cutaneous nerve entrapment plays an important role in neuropathic pain syndrome. Due to the advancement of ultrasound technology, the cutaneous nerves can be visualized by high-resolution ultrasound. As the cutaneous nerves course superficially in the subcutaneous layer, they are vulnerable to entrapment or collateral...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm7110457
更新日期:2018-11-21 00:00:00
abstract:AIM:Our aim was to investigate the characteristics, treatment and prognosis of patients with myocardial infarction (MI) treated outside a cardiology department (CD), compared with MI patients treated at a CD. METHODS:A cohort of 1310 patients diagnosed with MI at eight Swedish hospitals in 2011 were included in this o...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm10010106
更新日期:2020-12-30 00:00:00
abstract:BACKGROUND AND AIMS:The Multidimensional Prognostic Index (MPI), an objective and quantifiable tool based on the Comprehensive Geriatric Assessment, has been shown to predict adverse outcomes in European cohorts. We conducted a validation study of the original MPI, and of adapted versions that accounted for the use of ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8111820
更新日期:2019-11-01 00:00:00
abstract::Differing beliefs about the acceptability of living-donor kidney transplants (LDKTs) have been proposed as explaining age, ethnic and socioeconomic disparities in their uptake. We investigated whether certain patient groups hold beliefs incompatible with LDKTs. This questionnaire-based case-control study was based at ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9010031
更新日期:2019-12-21 00:00:00
abstract::(1) Background: Acute respiratory distress syndrome (ARDS) following cardiac arrest is common and associated with in-hospital mortality. We aim to investigate whether lung compliance during targeted temperature management is associated with neurological outcome in patients with ARDS after out-of-hospital cardiac arres...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9020527
更新日期:2020-02-14 00:00:00
abstract::Because of limitations caused by unique complications of free flap reconstruction, the Clavien-Dindo classification was modified to include grade "IIIc" for "partial or total free flap failure." From 2013 to 2018, 116 patients who had undergone free flap reconstruction for head and neck cancer with grade III or higher...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9113770
更新日期:2020-11-22 00:00:00