Abstract:
:Some temporary double enterostomies (DES) or entero-atmospheric fistulas (EAF) have high output and are responsible for Type 2 intestinal failure. Intravenous supplementations (IVS) for parenteral nutrition and hydration compensate for intestinal losses. Chyme reinfusion (CR) artificially restores continuity pending surgical closure. CR treats intestinal failure and is recommended by European Society for Clinical Nutrition and Metabolism (ESPEN) and American Society for Parenteral and Enteral Nutrition (ASPEN) when possible. The objective of this study was to show changes in nutritional status, intestinal function, liver tests, IVS needs during CR, and the feasibility of continuing it at home. A retrospective study of 306 admitted patients treated with CR from 2000 to 2018 was conducted. CR was permanent such that a peristaltic pump sucked the upstream chyme and reinfused it immediately in a tube inserted into the downstream intestine. Weight, plasma albumin, daily volumes of intestinal and fecal losses, intestinal nitrogen, and lipid absorption coefficients, plasma citrulline, liver tests, and calculated indices were compared before and during CR in patients who had both measurements. The patients included 185 males and 121 females and were 63 ± 15 years old. There were 37 (12%), 269 (88%) patients with EAF and DES, respectively. The proximal small bowel length from the duodeno-jejunal angle was 108 ± 67 cm (n = 232), and the length of distal small intestine was 117 ± 72 cm (n = 253). The median CR start was 5 d (quartile 25-75%, 2-10) after admission and continued for 64 d (45-95), including 81 patients at home for 47 d (28-74). Oral feeding was exclusive 171(56%), with enteral supplement 122 (42%), or with IVS 23 (7%). Before CR, 211 (69%) patients had IVS for nutrition (77%) or for hydration (23%). IVS were stopped in 188 (89%) 2 d (0-7) after the beginning of CR and continued in 23 (11%) with lower volumes. Nutritional status improved with respect to weight gain (+3.5 ± 8.4%) and albumin (+5.4 ± 5.8 g/L). Intestinal failure was cured in the majority of cases as evidenced by the decrease in intestinal losses by 2096 ± 959 mL/d, the increase in absorption of nitrogen 32 ± 20%, of lipids 43 ± 30%, and the improvement of citrulline 13.1 ± 8.1 µmol/L. The citrulline increase was correlated with the length of the distal intestine. The number of patients with at least one liver test >2N decreased from 84-40%. In cases of Type 2 intestinal failure related to DES or FAE with an accessible and functional distal small bowel segment, CR restored intestinal functions, reduced the need of IVS by 89% and helped improve nutritional status and liver tests. There were no vital complications or infectious diarrhea described to date. CR can become the first-line treatment for intestinal failure related to double enterostomy and high output fistulas.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Picot D,Layec S,Seynhaeve E,Dussaulx L,Trivin F,Carsin-Mahe Mdoi
10.3390/nu12051376subject
Has Abstractpub_date
2020-05-11 00:00:00issue
5issn
2072-6643pii
nu12051376journal_volume
12pub_type
杂志文章相关文献
Nutrients文献大全abstract::Sedentary habits during childhood are associated with adverse health outcomes. The aim of this work was to cluster lifestyle behaviors and metabolic biomarkers to establish different patterns in children. Their physical and sedentary activities were evaluated by accelerometry, and questionnaires that included lifestyl...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12051288
更新日期:2020-05-01 00:00:00
abstract::Sofrito is a Mediterranean tomato-based sauce that typically also contains olive oil, onion, and garlic. The preparation of sofrito modifies the bioactive compounds (carotenoids and polyphenols) in the ingredients to more bioavailable forms, promoting cis-lycopene formation and polyphenol bioaccessibility. To evaluate...
journal_title:Nutrients
pub_type: 临床试验,杂志文章
doi:10.3390/nu11040851
更新日期:2019-04-15 00:00:00
abstract::To the best of our knowledge, no specific questionnaires on sports nutrition knowledge (NK) have been validated so far in Italian early adolescents. The aim of the present study was to validate a short (26-item) general and sports NK questionnaire in a group of Italian early adolescents. To this aim, the questionnaire...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12103121
更新日期:2020-10-13 00:00:00
abstract::Essential amino acids (EAA) consist of a group of nine amino acids that animals are unable to synthesize via de novo pathways. Recently, it has been found that most metazoans lack the same set of enzymes responsible for the de novo EAA biosynthesis. Here we investigate the sequence conservation and evolution of all th...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7010001
更新日期:2014-12-24 00:00:00
abstract::While studies revealed that the omega-3 polyunsaturated fatty acids (n-3 PUFA) and their mediators would be able to regulate several biological processes involved into the development of postpartum depression (PPD), evidence from observational studies remains mixed. The aim of the present study was to investigate the ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11040876
更新日期:2019-04-18 00:00:00
abstract::Antimicrobial peptides (AMPs) are components of the innate immune system and form the first defense against pathogens for various organisms. In the present study, we assessed whether CSP32, a novel AMP oligomer of bacitracin isolated from a strain of Bacillus spp., regulates the polarization of murine macrophage-like ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061603
更新日期:2020-05-29 00:00:00
abstract::Sweeteners are found in all types of foods, and their high consumption is associated with chronic degenerative diseases, such as diabetes and obesity, among others. A characterization was carried out of food products with sweeteners from the three biggest supermarkets at a national level; they were identified by the l...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10030338
更新日期:2018-03-11 00:00:00
abstract::Heart failure in older individuals is normally associated with a high body mass index and relatively low lean body mass due to, in part, a resistance to the normal anabolic effect of dietary protein. In this study we have investigated the hypothesis that consumption of a specially-formulated composition of essential a...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11061360
更新日期:2019-06-17 00:00:00
abstract::Natural killer (NK) cells have many functional activities, including cytotoxicity and the capacity to produce cytokines and chemokines. NK cell activity is regulated partly by eicosanoids, which are produced from arachidonic acid (ARA) and eicosapentaenoic (EPA) acid. In this study, we investigated the effects of long...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu5061949
更新日期:2013-05-29 00:00:00
abstract::Various aspects of protein intake are thought to be crucial for the prevention of sarcopenia in older adults. Information about the day-to-day variation in these aspects is lacking. Our objective was to examine whether daily protein intake, protein distribution across meals, number of meals providing adequate protein,...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10091217
更新日期:2018-09-03 00:00:00
abstract::Elevated blood pressure affects a great part of the elderly population and is the leading risk factor for cardiovascular disease. New approaches have been taken in the fight against this growing problem, in the form of diets (Mediterranean, Dietary Approaches to Stop Hypertension (DASH) and intermittent fasting). Rece...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061659
更新日期:2020-06-03 00:00:00
abstract:BACKGROUND:Vitamin D and calcium are important dietary compounds that affect bone mass, even if other minerals (potassium, zinc, etc.) and vitamins (A, C and K) are also involved. Vitamin D and certain minerals, in fact, play an important role in calcium homeostasis and calcium absorption. Hip fracture incidence is hig...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12061743
更新日期:2020-06-10 00:00:00
abstract::This study describes baseline intakes of sodium and other nutrients in a multi-ethnic sample of hemodialysis patients in New Zealand participating in the SoLID Trial between May/2013 to May/2016. Baseline 3-day weighed food record collections were analyzed using Foodworks 8 Professional food composition database, supp...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10040502
更新日期:2018-04-18 00:00:00
abstract::Dietary carotenoids, plant pigments with anti-oxidant properties, accumulate in neural tissue and are often found in lower concentrations among individuals with obesity. Given previous evidence of negative associations between excess adiposity and memory, it is possible that greater carotenoid status may confer neurop...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11040768
更新日期:2019-04-02 00:00:00
abstract::Although the association of vitamin D levels with cardiovascular risk profiles among Hispanics/Latinos has been studied, little is known about this association among Hispanics/Latinos with chronic conditions. This pilot study determined serum vitamin D and parathyroid hormone (PTH) levels in a sample of participants f...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11081959
更新日期:2019-08-20 00:00:00
abstract::The present study investigated the effects of breast tumors on the blood and tissue distribution of essential trace mineral selenium (Se), and oxidative stress status of mice. Female 10-week-old BALB/cByJNarl mice were randomly assigned into control (CNL) and breast tumor-bearing (TB) groups. TB mice were injected sub...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu5020594
更新日期:2013-02-20 00:00:00
abstract::Background: Two different species of sage, Salvia officinalis and Salvia lavandulaefolia, have demonstrated activities in cognitive function during preclinical and clinical studies related to impaired health situations or single administration. Different memory processes have been described to be significantly and pos...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061777
更新日期:2020-06-15 00:00:00
abstract::This study sought to elucidate the multi-level factors that influence behaviors underlying high childhood stunting and widespread micronutrient deficiencies in Kiribati. This two-phase formative research study had an emergent and iterative design using the socio-ecological model as the guiding theoretical framework. P...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11061330
更新日期:2019-06-13 00:00:00
abstract::Dietary restraint is a commonly reported practice observed among young females. The practice remains controversial and can be interpreted as a beneficial self-regulating behavior or the opposite, an eating disorder that may have a detrimental effect on health. The aim of this short report was to investigate if dietary...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8120796
更新日期:2016-12-19 00:00:00
abstract::Several studies have linked increased intake of dietary fibre to improvement in the management of body weight. Dietary fibre from resistant starch (RS) has been shown to have an impact on food intake in normal weight individuals, but its role in obesity is unknown. The present study aimed to investigate the short-term...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu10121993
更新日期:2018-12-15 00:00:00
abstract:BACKGROUND:Iodine supplementation during pregnancy in areas with mild-to-moderate iodine deficiency is still debated. METHODS:A single-center, randomized, single-blind and placebo-controlled (3:2) trial was conducted. We enrolled 90 women before 12 weeks of gestation. From enrollment up until 8 weeks after delivery, 5...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11112639
更新日期:2019-11-04 00:00:00
abstract::Zinc (Zn) deficiency is a prevalent micronutrient insufficiency. Although the gut is a vital organ for Zn utilization, and Zn deficiency is associated with impaired intestinal permeability and a global decrease in gastrointestinal health, alterations in the gut microbial ecology of the host under conditions of Zn defi...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu7125497
更新日期:2015-11-27 00:00:00
abstract::The aim of this study was to analyze the anthropometric characteristics and sport supplement (SS) consumption patterns of heavyweight and lightweight international rowers. Methods: The 13 heavyweights (11 males) and seven lightweights (five males) of the Spanish National Rowing Team were recruited for the study. Body ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12123871
更新日期:2020-12-18 00:00:00
abstract::This is the first study to evaluate vitamin K status in relation to dietary intake and phenylalanine dietary compliance in patients with phenylketonuria (PKU). The dietary and PKU formula intake of vitamin K was calculated in 34 PKU patients, with vitamin K status determined by the measurement of prothrombin induced b...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061772
更新日期:2020-06-14 00:00:00
abstract::Eating behavior is an important aspect for dietary quality and long-term health. This study examined associations between eating vegetables first at a meal and food intakes among preschool children in Tokyo, Japan. We used cross-sectional data of 135 preschool children from seven nursery schools in Adachi City, Tokyo,...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061762
更新日期:2020-06-12 00:00:00
abstract::The medicinal use of cocoa has a long history dating back almost five hundred years when Hernán Cortés's first experienced the drink in Mesoamerica. Doctors in Europe recommended the beverage to patients in the 1700s, and later American physicians followed suit and prescribed the drink in early America--ca. 1800s. Thi...
journal_title:Nutrients
pub_type: 历史文章,杂志文章,评审
doi:10.3390/nu5103854
更新日期:2013-09-26 00:00:00
abstract::The objective of the present study is to investigate the relationships between body composition, nutritional profile, muscular fitness (MF) and bone health in a sample of children and adolescents from Colombia. Participants included 1118 children and adolescents (54.6% girls). Calcaneal broadband ultrasound attenuatio...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9020106
更新日期:2017-02-03 00:00:00
abstract::A high intake of refined carbohydrates, particularly the monosaccharide fructose, has been attributed to the growing epidemics of obesity and type-2 diabetes. Animal studies have helped elucidate the metabolic effects of dietary fructose, however, variations in study design make it difficult to draw conclusions. The a...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8090577
更新日期:2016-09-20 00:00:00
abstract::The objective of the present study is to analyze the effects of motor mental imagery training on tennis service performance among tennis athletes who fast during Ramadan. Participants were 38 young male tennis players, randomly divided into two groups: Imaging Training (IMG, n = 18) and control group (CG, n = 20). The...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12041035
更新日期:2020-04-09 00:00:00
abstract::Studies suggest that haem, non-haem iron and total iron intake may be related to non-communicable diseases, especially metabolic syndrome. This study was undertaken to investigate the association of haem, non-haem iron and total iron intake with metabolic syndrome and its components. A cross-sectional population-based...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10030314
更新日期:2018-03-07 00:00:00