Prognostic significance of helicobacter pylori-infection in gastric diffuse large B-cell lymphoma.

abstract：BACKGROUND:New disease mapping techniques widely used in small-area studies enable disease distribution patterns to be identified and have become extremely popular in the field of public health. This paper reports on trends in the geographical mortality patterns of the most frequent cancers in Spain, over a period of 2...

journal_title：BMC cancer

authors： López-Abente G,Aragonés N,Pérez-Gómez B,Pollán M,García-Pérez J,Ramis R,Fernández-Navarro P

更新日期：2014-07-24 00:00:00

abstract：BACKGROUND:A low cost and accurate method for detecting high-risk (HR) human papillomavirus (HPV) is important to permit HPV testing for cervical cancer prevention. We used a commercially available HPV method (H13, Hybribio) which was documented to function accurately in a reduced volume of cervical specimen to determi...

journal_title：BMC cancer

authors： Lou H,Gharzouzi E,Guerra SP,Fokom Domgue J,Sawitzke J,Villagran G,Garland L,Boland JF,Wagner S,Rosas H,Troxler J,McMillen H,Kessing B,Alvirez E,Castillo M,Morales H,Argueta V,Rosingh A,van Aerde-van Nunen FJHB,Lopez

更新日期：2018-05-15 00:00:00

abstract：BACKGROUND:For most patients, pancreatic adenocarcinoma responds poorly to treatment, and novel therapeutic approaches are needed. Standard-of-care paclitaxel (PTX), combined with birinapant (BRP), a bivalent mimetic of the apoptosis antagonist SMAC (second mitochondria-derived activator of caspases), exerts synergisti...

journal_title：BMC cancer

authors： Niu J,Wang X,Qu J,Mager DE,Straubinger RM

更新日期：2020-10-23 00:00:00

abstract：BACKGROUND:Neoadjuvant chemotherapy (NAC) is a standard treatment for stage II/III breast cancer patients, and response to NAC is a useful prognostic marker. Since its introduction, 6-8 cycles of NAC has become the standard regimen to improve the outcome of these patients. The purpose of this study is to evaluate the p...

journal_title：BMC cancer

authors： Yang Y,Im SA,Keam B,Lee KH,Kim TY,Suh KJ,Ryu HS,Moon HG,Han SW,Oh DY,Han W,Kim TY,Park IA,Noh DY

更新日期：2016-07-21 00:00:00

abstract：BACKGROUND:Matrix metalloproteinases (MMPs) are crucially involved in the regulation of multiple stages of cancer progression. Elevated MMP levels have been associated with the development of metastases and poor prognosis in several types of cancer. However, the role of MMPs in osteosarcoma and their prognostic value i...

journal_title：BMC cancer

authors： Kunz P,Sähr H,Lehner B,Fischer C,Seebach E,Fellenberg J

更新日期：2016-03-15 00:00:00

abstract：BACKGROUND:The aim of the present study was to investigate the association between matrix metalloproteinase-9 (MMP-9) expression with BRAF V600E mutation and clinicopathological features, in Iranian papillary thyroid cancer (PTC) patients. METHODS:In total, 90 participants including 60 PTC patients (15 males and 45 fe...

journal_title：BMC cancer

authors： Zarkesh M,Zadeh-Vakili A,Akbarzadeh M,Fanaei SA,Hedayati M,Azizi F

更新日期：2018-12-03 00:00:00

abstract：BACKGROUND:Adding bevacizumab to chemotherapy improves response rates and progression-free survival (PFS) in metastatic breast cancer (mBC). We aimed to demonstrate decreased toxicity with metronomic chemotherapy/bevacizumab compared with paclitaxel/bevacizumab. METHODS:This multicenter, randomized phase III trial com...

journal_title：BMC cancer

authors： Rochlitz C,Bigler M,von Moos R,Bernhard J,Matter-Walstra K,Wicki A,Zaman K,Anchisi S,Küng M,Na KJ,Bärtschi D,Borner M,Rordorf T,Rauch D,Müller A,Ruhstaller T,Vetter M,Trojan A,Hasler-Strub U,Cathomas R,Winterhalde

更新日期：2016-10-10 00:00:00

abstract：BACKGROUND:The oncofetal protein insulin-like growth factor II mRNA binding protein 3 (IMP3) is an important factor for cell-migration and adhesion in malignancies. Recent studies have shown a remarkable overexpression of IMP3 in different human malignant neoplasms and also revealed it as an important prognostic marker...

journal_title：BMC cancer

authors： Ikenberg K,Fritzsche FR,Zuerrer-Haerdi U,Hofmann I,Hermanns T,Seifert H,Müntener M,Provenzano M,Sulser T,Behnke S,Gerhardt J,Mortezavi A,Wild P,Hofstädter F,Burger M,Moch H,Kristiansen G

更新日期：2010-06-30 00:00:00

abstract：BACKGROUND:Presently available flow cytometric methods of bromodeoxyuridine (BrdUrd) labelling do not provide information on the cell cycle time (TC) and the growth fraction (GF). In this paper, we describe a novel and simple method to estimate TC and GF from flow cytometric analysis of a single tumour sample after Brd...

journal_title：BMC cancer

authors： Eidukevicius R,Characiejus D,Janavicius R,Kazlauskaite N,Pasukoniene V,Mauricas M,Den Otter W

更新日期：2005-09-22 00:00:00

abstract：BACKGROUND:Breast cancer is the most common malignancy in women world-wide. Triple negative breast cancer (TNBC) is a highly aggressive subtype that lacks expression of hormone receptors for estrogen, progesterone and human epidermal growth factor 2; and is associated with a high propensity for metastatic spread. Sever...

journal_title：BMC cancer

authors： Avery-Kiejda KA,Braye SG,Forbes JF,Scott RJ

更新日期：2014-04-11 00:00:00

abstract：BACKGROUND:A universal hallmark of cancer cells is the change in their glycosylation phenotype. One of the most frequent alterations in the normal glycosylation pattern observed during carcinogenesis is the enhancement of α(1,6)linked fucose residues of glycoproteins, due to the up-regulation of the α(1,6)fucosyltransf...

journal_title：BMC cancer

authors： Muinelo-Romay L,Villar-Portela S,Cuevas E,Gil-Martín E,Fernández-Briera A

更新日期：2011-12-07 00:00:00

abstract：BACKGROUND:MicroRNA-21 (miR-21) is up-regulated in many cancers, including colorectal cancer (CRC). Nevertheless, the function of miR-21 in CRC and the mechanism underlying that function is still unclear. METHODS:After analyzing the expression of miR-21 and Sec23A in CRC cell lines, we transfected the highest miR-21 e...

journal_title：BMC cancer

authors： Li C,Zhao L,Chen Y,He T,Chen X,Mao J,Li C,Lyu J,Meng QH

更新日期：2016-08-05 00:00:00

abstract：BACKGROUND:The immune system plays an important role in the multifactorial biologic system during the development of neoplasias. However, the involvement of the inflammatory response in the promotion/control of malignant cells is still controversial, and the cell subsets and the mechanisms involved are poorly investiga...

journal_title：BMC cancer

authors： Estrela-Lima A,Araújo MS,Costa-Neto JM,Teixeira-Carvalho A,Barrouin-Melo SM,Cardoso SV,Martins-Filho OA,Serakides R,Cassali GD

更新日期：2010-06-04 00:00:00

abstract：BACKGROUND:Tobacco smoke exposure may be associated with increased breast cancer risk, although the evidence supporting the association is inconclusive. We conducted a case-control study in Delaware, incorporating detailed exposure assessment for active and secondhand smoke at home and in the workplace. METHODS:Primar...

journal_title：BMC cancer

authors： Rollison DE,Brownson RC,Hathcock HL,Newschaffer CJ

更新日期：2008-06-02 00:00:00

abstract：BACKGROUND:Circular RNAs (circRNAs) have emerged as a novel category of non-coding RNA, which exhibit a pivotal effect on regulating gene expression and biological functions, yet how circRNAs function in osteosarcoma (OSA) still demands further investigation. This study aimed at probing into the function of hsa_circ_00...

journal_title：BMC cancer

authors： Li H,He L,Tuo Y,Huang Y,Qian B

更新日期：2020-10-23 00:00:00

abstract：BACKGROUND:Metformin and the thiazolidinediones (TZDs) may have a protective effect against the development of lung cancer. METHODS:Patients with diabetes mellitus (DM) were identified from the electronic medical records of the Cleveland Clinic. Diabetics with lung cancer were identified then verified by direct review...

journal_title：BMC cancer

authors： Mazzone PJ,Rai H,Beukemann M,Xu M,Jain A,Sasidhar M

更新日期：2012-09-14 00:00:00

abstract：OBJECTIVES:The present study aims to evaluate long-term side-effects and outcomes and confirm prognostic factors after stereotactic body radiotherapy (SBRT) of pulmonary lesions. This is the first work that combines the investigated data from patient charts and patient-reported outcome (PRO) up to 14 years after therap...

journal_title：BMC cancer

authors： Kessel KA,Grosser RCE,Kraus KM,Hoffmann H,Oechsner M,Combs SE

更新日期：2020-05-19 00:00:00

abstract：BACKGROUND:Identifying cellular signaling pathways that become corrupted in the presence of androgens that increase the metastatic potential of organ-confined tumor cells is critical to devising strategies capable of attenuating the metastatic progression of hormone-naïve, organ-confined tumors. In localized prostate c...

journal_title：BMC cancer

authors： Hsiao JJ,Ng BH,Smits MM,Wang J,Jasavala RJ,Martinez HD,Lee J,Alston JJ,Misonou H,Trimmer JS,Wright ME

更新日期：2015-03-31 00:00:00

abstract：BACKGROUND:Brain tumor vasculature can be significantly compromised and leakier than that of normal brain blood vessels. Little is known if there are vascular permeability alterations in the brain adjacent to tumor (BAT). Changes in BAT permeability may also lead to increased drug permeation in the BAT, which may exert...

journal_title：BMC cancer

authors： Mohammad AS,Adkins CE,Shah N,Aljammal R,Griffith JIG,Tallman RM,Jarrell KL,Lockman PR

更新日期：2018-12-07 00:00:00

abstract：BACKGROUND:The use of computerized systems to support evidence-based practice is commonplace in contemporary medicine. Despite the prolific use of electronic support systems there has been relatively little research on the uptake of web-based systems in the oncology setting. Our objective was to examine the uptake of a...

journal_title：BMC cancer

authors： Langton JM,Pesa N,Rushton S,Ward RL,Pearson SA

更新日期：2013-03-12 00:00:00

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) have become the mainstay of treatment for advanced renal cell carcinoma (RCC), but it has been unclear whether the antitumor effect of TKIs depends on the organ where the RCC metastasis is located. We previously reported that the FDG accumulation assessed by FDG PET/CT, was ...

journal_title：BMC cancer

authors： Kakizoe M,Yao M,Tateishi U,Minamimoto R,Ueno D,Namura K,Makiyama K,Hayashi N,Sano F,Kishida T,Kobayashi K,Noguchi S,Ikeda I,Ohgo Y,Taguri M,Morita S,Inoue T,Kubota Y,Nakaigawa N

更新日期：2014-06-02 00:00:00

abstract：BACKGROUND:Although preoperative radiotherapy (RT) is widely used as the initial treatment for locally advanced rectal cancer (RC) in the neoadjuvant setting, factors determining clinical response have not been adequately defined. In order to find other factors possibly related with radiosensitivity, we evaluated the r...

journal_title：BMC cancer

authors： Kitayama J,Yasuda K,Kawai K,Sunami E,Nagawa H

更新日期：2011-02-10 00:00:00

abstract：BACKGROUND:RNA from exosomes and other microvesicles contain transcripts of tumour origin. In this study we sought to identify biomarkers of glioblastoma multiforme in microvesicle RNA from serum of affected patients. METHODS:Microvesicle RNA from serum from patients with de-novo primary glioblastoma multiforme (N = 9...

journal_title：BMC cancer

authors： Noerholm M,Balaj L,Limperg T,Salehi A,Zhu LD,Hochberg FH,Breakefield XO,Carter BS,Skog J

更新日期：2012-01-17 00:00:00

abstract：BACKGROUND:With the advent of novel drugs improved overall survival in patients with multiple myeloma, including patients who received up-front autologous stem cell transplantation (ASCT), has been reported from several centers. Here we report on overall survival in a population-based cohort of patients receiving ASCT ...

journal_title：BMC cancer

authors： Tangen JM,Tjønnfjord GE,Gulbrandsen N,Gedde-Dahl T,Stormorken E,Anderson K,Vo CD,Schjesvold FH,For Oslo Myeloma Center.

更新日期：2018-08-08 00:00:00

abstract：BACKGROUND:Pseudomonas fluorescens lectin (PFL) belongs to a recently discovered anti-HIV lectin family and induces anoikis-like cell death of MKN28 gastric cancer cells by causing α2 integrin internalization through recognition of high mannose glycans; however, the detailed anti-cancer mechanism is not fully elucidate...

journal_title：BMC cancer

authors： Sato Y,Kubo T,Morimoto K,Yanagihara K,Seyama T

更新日期：2016-02-06 00:00:00

abstract：BACKGROUND:MicroRNAs in solid malignancies can behave as predictors of either good or poor outcome. This is the case with members of the miR-200 family, which are the primary regulators of the epithelial to mesenchymal transition and have been reported to act as both oncogenes and tumor suppressors. This study assessed...

journal_title：BMC cancer

authors： Prislei S,Martinelli E,Mariani M,Raspaglio G,Sieber S,Ferrandina G,Shahabi S,Scambia G,Ferlini C

更新日期：2013-02-08 00:00:00

abstract：BACKGROUND:New Zealand and Australia have the highest incidence and mortality rates from cutaneous melanoma in the world. The predominantly fair-skinned New Zealanders and Australians both enjoy sun, tanned skin and the outdoors, and differences in these activities among generations have been important determinants of ...

journal_title：BMC cancer

authors： Sneyd MJ,Cox B

更新日期：2013-08-06 00:00:00

abstract：BACKGROUND:Loss of lean body mass (LBM) is a common occurrence after treatment for breast cancer and is related to deleterious metabolic health outcomes [Clin Oncol, 22(4):281-288, 2010; Appl Physiol Nutr Metab, 34(5):950-956, 2009]. The aim of this research is to determine the effectiveness of long chain omega-3 fatty...

journal_title：BMC cancer

authors： McDonald C,Bauer J,Capra S,Coll J

更新日期：2014-04-16 00:00:00

abstract：BACKGROUND:Breast carcinomas with neuroendocrine features (NEBC) are a very rare entity of mammary neoplasms, WHO classification of which has recently been revised. There are very limited data available about the clinical behaviour and treatment options of NEBC. METHODS:We collected retrospectively patients with NEBC ...

journal_title：BMC cancer

authors： Roininen N,Takala S,Haapasaari KM,Jukkola-Vuorinen A,Mattson J,Heikkilä P,Karihtala P

更新日期：2017-01-24 00:00:00

abstract：BACKGROUND:The prognostic value of p53 protein expression in esophageal cancer has been evaluated, but the results remain inconclusive and no consensus has yet been achieved. This meta-analysis was conducted to quantitatively assess the prognostic significance of p53 expression in esophageal cancer. METHODS:Publicatio...

journal_title：BMC cancer

authors： Wang L,Yu X,Li J,Zhang Z,Hou J,Li F

更新日期：2016-07-01 00:00:00