Characterizing idiopathic pulmonary fibrosis patients using US Medicare-advantage health plan claims data.

Abstract:

BACKGROUND:Idiopathic pulmonary fibrosis (IPF) is a rare life-threating interstitial lung disease (ILD). This study characterizes demographics, health care utilization, and comorbidities among elderly IPF patients and estimates prevalence and incidence rates for selected outcomes. METHODS:Cohort study using a large US health insurance database (Optum's Medicare Advantage plan). INCLUSION CRITERIA:≥ 1 diagnosis code for IPF (2008 - 2014), age ≥65 years, no diagnosis of IPF or other ILD in prior 12 months. Demographics, health care utilization, comorbidities and incidence rates for various outcomes were estimated. Follow-up continued until the earliest of: health plan disenrollment, death, a claim for another known cause of ILD, or end of the study period. RESULTS:4,716 patients were eligible; 53.4% had IPF diagnostic testing. Median age was 77.5 years, 50.3% were male, median follow-up time was 0.8 years. Incidence rates ranged from 1.0/1,000 person-years (lung transplantation) to 374.3/1,000 person-years (arterial hypertension). Baseline characteristics and incidence rates were similar for cohorts of patients with and without IPF diagnostic testing. CONCLUSIONS:Elderly IPF patients experience a variety of comorbidities before and after IPF diagnosis. Therapies for IPF and for the associated comorbidities may reduce morbidity and associated health care utilization of these patients.

journal_name

BMC Pulm Med

journal_title

BMC pulmonary medicine

authors

Mortimer K,Hartmann N,Chan C,Norman H,Wallace L,Enger C

doi

10.1186/s12890-018-0759-5

subject

Has Abstract

pub_date

2019-01-10 00:00:00

pages

11

issue

1

issn

1471-2466

pii

10.1186/s12890-018-0759-5

journal_volume

19

pub_type

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