Study protocol for a randomised controlled trial evaluating the efficacy of a telehealth program--management of asthma with supportive telehealth of respiratory function in pregnancy (MASTERY©).

abstract：BACKGROUND:As supra-physiological intake of corticosteroids is a well known risk factor for the development of adrenal insufficiency, we investigated the function of the hypothalamic-pituitary-adrenal (HPA) axis during a 14-day course of systemic corticosteroids in patients with acute exacerbation of chronic obstructiv...

journal_title：BMC pulmonary medicine

authors： Schuetz P,Christ-Crain M,Schild U,Süess E,Facompre M,Baty F,Nusbaumer C,Brutsche M,Müller B

更新日期：2008-01-26 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is hallmarked by inflammatory processes and a progressive decline of lung function. YKL-40 is a potential biomarker of inflammation and mortality in patients suffering from inflammatory lung disease, but its prognostic value in patients with COPD remains unknown. ...

journal_title：BMC pulmonary medicine

authors： Holmgaard DB,Mygind LH,Titlestad IL,Madsen H,Pedersen SS,Johansen JS,Pedersen C

更新日期：2013-12-30 00:00:00

abstract：BACKGROUND:This study was conducted in order to determine the prevalence of asthma and associated risk factors in the adult population of Karachi, Pakistan. METHODS:This multi-stage, cross-sectional survey was conducted from May 2014-August 2015; comprising 1629 adults in 75 randomly selected clusters in Karachi, Paki...

journal_title：BMC pulmonary medicine

authors： Razzaq S,Nafees AA,Rabbani U,Irfan M,Naeem S,Khan MA,Fatmi Z,Burney P

更新日期：2018-12-04 00:00:00

abstract：BACKGROUND:COVID-19 is a systemic viral infection which mainly targets the human respiratory system with many secondary clinical manifestations especially affecting the hematopoietic system and haemostasis. Few studies have highlighted the prognostic value of blood findings such as lymphopenia, neutrophil/lymphocyte ra...

journal_title：BMC pulmonary medicine

authors： Lim AYH,Goh JL,Chua MCW,Heng BH,Abisheganaden JA,George PP

更新日期：2021-01-22 00:00:00

abstract：BACKGROUND:Treatment of patients with Cystic Fibrosis homozygous for the Phe508del gene, with Lumacaftor /Ivacaftor (LUM/IVA) improves outcomes in patients with FEV1 > 40% predicted. We set out to observe the most sensitive clinical measure that would change with treatment in terms of exercise capacity or lung function...

journal_title：BMC pulmonary medicine

authors： Wark PAB,Cookson K,Thiruchelvam T,Brannan J,Dorahy DJ

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:Asthma is a common chronic disease among young adults, and several studies have reported increased mortality rates in patients with asthma. However, no study has described sudden unexpected death in a nationwide setting in patients with uncontrolled asthma. We defined uncontrolled asthma as a previous hospit...

journal_title：BMC pulmonary medicine

authors： Gullach AJ,Risgaard B,Lynge TH,Jabbari R,Glinge C,Haunsø S,Backer V,Winkel BG,Tfelt-Hansen J

更新日期：2015-04-14 00:00:00

abstract：BACKGROUND:Malignant pleural mesothelioma (MPM) is marked by its difficult diagnosis and poor prognosis. Medical thoracoscopy (MT) is an effective and safe procedure for the diagnosis of exudative pleural effusions and many factors associated with poor prognosis of MPM. We conducted this study to investigate the value ...

journal_title：BMC pulmonary medicine

authors： Xu LL,Yang Y,Wang Z,Wang XJ,Tong ZH,Shi HZ

更新日期：2018-04-03 00:00:00

abstract：BACKGROUND:Primary Ciliary Dyskinesia (PCD) is also known as immotile-cilia syndrome, an autosomal recessive disorder of ciliary function, leading to mucus retention in the respiratory system in childhood. Our knowledge in the pathophysiological aspect of this devastating disorder is increasing with the advancement of ...

journal_title：BMC pulmonary medicine

authors： Al Mutairi F,Alkhalaf R,Alkhorayyef A,Alroqi F,Yusra A,Umair M,Nouf F,Khan A,Meshael A,Hamad A,Monira A,Asiri A,Alhamoudi KM,Alfadhel M

更新日期：2020-05-15 00:00:00

abstract：BACKGROUND:Programmed cell death 5 (PDCD5) was first identified as an apoptosis-promoting protein and involved in some autoimmune diseases and inflammatory processes. Our previous study demonstrated greater expression of serum PDCD5 in asthmatic patients than controls. This study aimed to further explore the significan...

journal_title：BMC pulmonary medicine

authors： Diao X,Wang J,Zhu H,He B

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:Improvement in health-related quality of life (HRQL) has been suggested as an alternative treatment goal of non-tuberculous mycobacterial pulmonary disease (NTM-PD). This study was performed to elucidate the longitudinal changes in HRQL using St. George's Respiratory Questionnaire (SGRQ) among patients with ...

journal_title：BMC pulmonary medicine

authors： Kwak N,Kim SA,Choi SM,Lee J,Lee CH,Yim JJ

更新日期：2020-05-07 00:00:00

abstract：BACKGROUND:Interleukin-9 (IL-9)-targeted therapies may offer a novel approach for treating asthmatics. Two randomized placebo-controlled studies were conducted to assess the safety profile and potential efficacy of multiple subcutaneous doses of MEDI-528, a humanized anti-IL-9 monoclonal antibody, in asthmatics. METHO...

journal_title：BMC pulmonary medicine

authors： Parker JM,Oh CK,LaForce C,Miller SD,Pearlman DS,Le C,Robbie GJ,White WI,White B,Molfino NA,MEDI-528 Clinical Trials Group.

更新日期：2011-02-28 00:00:00

abstract：BACKGROUND:CHCHD2 was identified a novel cell migration-promoting gene, which could promote cell migration and altered cell adhesion when ectopically overexpressed in NIH3T3 fibroblasts, and it was identified as a protein necessary for OxPhos function as well. However, the clinic relevance of CHCHD2 expression in NSCLC...

journal_title：BMC pulmonary medicine

authors： Yin X,Xia J,Sun Y,Zhang Z

更新日期：2020-02-13 00:00:00

abstract：BACKGROUND:Pulmonary non-Hodgkin lymphoma (NHL) is rare. The most frequent subtype of pulmonary NHL is low-grade B-cell lymphoma, such as lymphoma of mucosa-associated lymphoma tissue. Extranodal natural killer cell/T-cell lymphoma, nasal type (ENKL) is characterized by predominant extranodal involvement and associatio...

journal_title：BMC pulmonary medicine

authors： Yabushita T,Yoshioka S,Furumiya T,Nakamura M,Yamashita D,Imai Y,Ishikawa T

更新日期：2019-02-21 00:00:00

abstract：BACKGROUND:Diagnosis of lower respiratory tract infections (LRTI) depends on the presence of clinical, radiological and microbiological findings. Endotracheal suction aspirate (ETSA) is the commonest respiratory sample sent for culture from intubated patients. Very few studies have compared quantitative and semi-quanti...

journal_title：BMC pulmonary medicine

authors： Rattani S,Farooqi J,Jabeen G,Chandio S,Kash Q,Khan A,Jabeen K

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND:To investigate if age, gender and smoking are associated with airway wall thickness (AWT) measured by high resolution computed tomography (HRCT) and if higher AWT is associated with lower levels of pulmonary function in healthy current- and never-smokers with a wide age range. METHODS:HRCT scans were perfor...

journal_title：BMC pulmonary medicine

authors： Telenga ED,Oudkerk M,van Ooijen PM,Vliegenthart R,Ten Hacken NH,Postma DS,van den Berge M

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Neutrophil-to-lymphocyte ratio (NLR) is a biomarker of inflammation in chronic obstructive pulmonary disease (COPD) patients. But, a meaningful threshold and the longitudinal changes are unknown. We aimed to investigate the association between NLR and the clinical characteristics of COPD patients and to dete...

journal_title：BMC pulmonary medicine

authors： Sakurai K,Chubachi S,Irie H,Tsutsumi A,Kameyama N,Kamatani T,Koh H,Terashima T,Nakamura H,Asano K,Betsuyaku T

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Breathlessness is a common and distressing symptom affecting many patients with advanced disease both from malignant and non-malignant origin. A combination of pharmacological and non-pharmacological measures is necessary to treat this symptom successfully. Breathlessness services in various compositions aim...

journal_title：BMC pulmonary medicine

authors： Bausewein C,Jolley C,Reilly C,Lobo P,Kelly J,Bellas H,Madan P,Panell C,Brink E,De Biase C,Gao W,Murphy C,McCrone P,Moxham J,Higginson IJ

更新日期：2012-09-19 00:00:00

abstract：BACKGROUND:Exposure to perinatal anxiety affects disease susceptibility in offspring but studies on the association between perinatal anxiety and gene polymorphisms are lacking. This study aimed to elucidate the interaction between perinatal anxiety and polymorphisms in antioxidant defense and innate immunity genes on ...

journal_title：BMC pulmonary medicine

authors： Lee E,Chang HY,Lee KS,Suh DI,Yu HS,Kang MJ,Choi IA,Park J,Kim KW,Shin YH,Ahn KM,Kwon JY,Choi SJ,Lee KJ,Won HS,Yang SI,Jung YH,Kim HY,Seo JH,Kwon JW,Kim BJ,Kim HB,Lee SY,Kim EJ,Lee JS,Keyes KM,Shin YJ,

更新日期：2014-09-29 00:00:00

abstract：BACKGROUND:Exercise capacity is impaired in pulmonary arterial hypertension (PAH). We hypothesized that cardiovascular reserve abnormalities would be associated with impaired hemodynamic response to pharmacological stress and worse outcome in PAH. METHODS:Eighteen PAH patients (p) group 1 NYHA class II/III and ten con...

journal_title：BMC pulmonary medicine

authors： Domingo E,Grignola JC,Aguilar R,Arredondo C,Bouteldja N,Messeguer ML,Roman A

更新日期：2014-04-24 00:00:00

abstract：BACKGROUND:The importance of the lung parenchyma in the pathophysiology of asthma has previously been demonstrated. Considering that nitric oxide synthases (NOS) and arginases compete for the same substrate, it is worthwhile to elucidate the effects of complex NOS-arginase dysfunction in the pathophysiology of asthma, ...

journal_title：BMC pulmonary medicine

authors： Aristoteles LR,Righetti RF,Pinheiro NM,Franco RB,Starling CM,da Silva JC,Pigati PA,Caperuto LC,Prado CM,Dolhnikoff M,Martins MA,Leick EA,Tibério IF

更新日期：2013-08-15 00:00:00

abstract：BACKGROUND:Recurrent airway infections are common in patients with Down's syndrome (DS). Hence, ruling out Cystic Fibrosis (CF) in these patients is often required. In the past, the value of sweat testing - the gold standard to diagnose CF - has been questioned in DS as false positive results have been reported. Howeve...

journal_title：BMC pulmonary medicine

authors： Ruf K,Demerath A,Hebestreit H,Kunzmann S

更新日期：2018-01-16 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation that is due to airway and/or alveolar abnormalities. The main causes of COPD are Gene-environment interactions associated with tobacco smoking (COPD-TS) and biomass smoke (COPD-BS). It is w...

journal_title：BMC pulmonary medicine

authors： Velasco-Torres Y,Ruiz-López V,Pérez-Bautista O,Buendía-Roldan I,Ramírez-Venegas A,Pérez-Ramos J,Falfán-Valencia R,Ramos C,Montaño M

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:Alveolar volume measured according to the American Thoracic Society-European Respiratory Society (ATS-ERS) guidelines during the single breath diffusion test can be underestimated when there is maldistribution of ventilation. Therefore, the alveolar volume calculated by taking into account the ATS-ERS guidel...

journal_title：BMC pulmonary medicine

authors： Prediletto R,Fornai E,Catapano G,Carli C

更新日期：2007-12-19 00:00:00

abstract：BACKGROUND:It is widely recognized that health-related quality of life (HRQL) is impaired in patients with Chronic Obstructive Pulmonary Disease (COPD), but there is a lack of research on longitudinal associations of COPD and HRQL. This study examined the effects of COPD in early stages of disease on HRQL over ten year...

journal_title：BMC pulmonary medicine

authors： Wacker ME,Hunger M,Karrasch S,Heinrich J,Peters A,Schulz H,Holle R

更新日期：2014-08-09 00:00:00

abstract：BACKGROUND:Fine needle aspiration is an important tool for diagnosis and preoperative evaluation of solitary nodules of the lung. It provides a definitive diagnosis in most patients at low cost with minimal trauma. However, because of the nature of the study and the presentation of the cells in a more distorted and inc...

journal_title：BMC pulmonary medicine

authors： Torkian B,Kanthan R,Burbridge B

更新日期：2003-09-08 00:00:00

abstract：BACKGROUND:Selection bias is a systematic error in epidemiologic studies that may seriously distort true measures of associations between exposure and disease. Observational studies are highly susceptible to selection bias, and researchers should therefore always examine to what extent selection bias may be present in ...

journal_title：BMC pulmonary medicine

authors： Johannessen A,Verlato G,Benediktsdottir B,Forsberg B,Franklin K,Gislason T,Holm M,Janson C,Jögi R,Lindberg E,Macsali F,Omenaas E,Real FG,Saure EW,Schlünssen V,Sigsgaard T,Skorge TD,Svanes C,Torén K,Waatevik M,Nils

更新日期：2014-04-16 00:00:00

abstract：BACKGROUND:The collection of exhaled breath condensate (EBC) is a suitable and non-invasive method for evaluation of airway inflammation. Several studies indicate that the composition of the condensate and the recovery of biomarkers are affected by physical characteristics of the condensing device and collecting circum...

journal_title：BMC pulmonary medicine

authors： Hoffmeyer F,Raulf-Heimsoth M,Harth V,Bünger J,Brüning T

更新日期：2009-11-30 00:00:00

abstract：BACKGROUND:Gene expression changes in the structural cells of the airways are thought to play a role in the development of asthma and airway hyperresponsiveness. This includes changes to smooth muscle contractile machinery and epithelial barrier integrity genes. We used a targeted gene expression arrays to identify cha...

journal_title：BMC pulmonary medicine

authors： Pascoe CD,Obeidat M,Arsenault BA,Nie Y,Warner S,Stefanowicz D,Wadsworth SJ,Hirota JA,Jasemine Yang S,Dorscheid DR,Carlsten C,Hackett TL,Seow CY,Paré PD

更新日期：2017-12-11 00:00:00

abstract：BACKGROUND:The epidermal growth factor receptor (EGFR) mutation status assessment has become increasingly important given the significant impact of tyrosine kinase inhibitors in lung cancer management. Our aim was to compare real life operational characteristics for three EGFR mutation assays - two targeted approaches ...

journal_title：BMC pulmonary medicine

authors： Cernomaz AT,Macovei II,Pavel I,Grigoriu C,Marinca M,Baty F,Peter S,Zonda R,Brutsche M,Grigoriu B

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND:Pneumonia poses a significant burden to the U.S. health-care system. However, there are few data focusing on severe pneumonia, particularly cases of pneumonia associated with specialized care in intensive care units (ICU). METHODS:We used administrative and electronic medical record data from six integrated...

journal_title：BMC pulmonary medicine

authors： Storms AD,Chen J,Jackson LA,Nordin JD,Naleway AL,Glanz JM,Jacobsen SJ,Weintraub ES,Klein NP,Gargiullo PM,Fry AM

更新日期：2017-12-16 00:00:00