Longitudinal changes in health-related quality of life according to clinical course among patients with non-tuberculous mycobacterial pulmonary disease: a prospective cohort study.

abstract：BACKGROUND:Treatment of patients with Cystic Fibrosis homozygous for the Phe508del gene, with Lumacaftor /Ivacaftor (LUM/IVA) improves outcomes in patients with FEV1 > 40% predicted. We set out to observe the most sensitive clinical measure that would change with treatment in terms of exercise capacity or lung function...

journal_title：BMC pulmonary medicine

authors： Wark PAB,Cookson K,Thiruchelvam T,Brannan J,Dorahy DJ

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:In adults, overweight is associated with reduced lung function, in children evidence on this association is conflicting. We examined the association of body mass index (BMI) and waist circumference (WC) at age 12, and of persistently (at ages 8 and 12 years) high BMI and large WC, with forced vital capacity ...

journal_title：BMC pulmonary medicine

authors： Bekkers MB,Wijga AH,Gehring U,Koppelman GH,de Jongste JC,Smit HA,Brunekreef B

更新日期：2015-04-22 00:00:00

abstract：BACKGROUND:Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) has an extremely poor prognosis and there is currently no effective treatment for this condition. Direct hemoperfusion with a polymyxin B-immobilized fiber column (PMX-DHP) improves oxygenation, but it is unclear whether treatment of AE-IPF with PM...

journal_title：BMC pulmonary medicine

authors： Enomoto N,Mikamo M,Oyama Y,Kono M,Hashimoto D,Fujisawa T,Inui N,Nakamura Y,Yasuda H,Kato A,Mimuro S,Doi M,Sato S,Suda T

更新日期：2015-02-22 00:00:00

abstract：:Following publication of the original article [1], the authors flagged that the article had published with an error in 'Table 1'. ...

journal_title：BMC pulmonary medicine

authors： Kindermann A,Binder L,Baier J,Gündel B,Simm A,Haase R,Bartling B

更新日期：2020-01-21 00:00:00

abstract：BACKGROUND:During the past decades, numerous efforts have been made to decrease the death rate among lung cancer patients. Nonetheless, the improvement in long-term survival has been limited and lung cancer is still a devastating disease. DISCUSSION:With this article we would like to point out that survival of lung ca...

journal_title：BMC pulmonary medicine

authors： Heuvers ME,Hegmans JP,Stricker BH,Aerts JG

更新日期：2012-12-13 00:00:00

abstract：:Chemo-radiotherapy and systemic therapies have proven satisfactory outcomes as standard treatments for various thoracic malignancies; however, adverse pulmonary effects, like pneumonitis, can be life-threatening. Pneumonitis is caused by direct cytotoxic effect, oxidative stress, and immune-mediated injury. Radiothera...

journal_title：BMC pulmonary medicine

authors： Arroyo-Hernández M,Maldonado F,Lozano-Ruiz F,Muñoz-Montaño W,Nuñez-Baez M,Arrieta O

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:Irisin, a recently discovered myokine, is assumed to be secreted by muscle cells in response to exercise and is involved in the regulation of energy metabolism by browning white adipose tissue cells. However, due to the fact that previous studies revealed conflicting results concerning the association betwee...

journal_title：BMC pulmonary medicine

authors： Kerstholt N,Ewert R,Nauck M,Spielhagen T,Bollmann T,Stubbe B,Felix SB,Wallaschofski H,Gläser S,Friedrich N

更新日期：2015-04-22 00:00:00

abstract：BACKGROUND:Pulmonary surfactant D (SP-D) has important regulatory functions for innate immunity and has been implicated as a biomarker for chronic obstructive pulmonary disease (COPD). We hypothesized that COPD patients would have reduced bronchoalveolar lavage (BAL) fluid SP-D levels compared to healthy smoking and no...

journal_title：BMC pulmonary medicine

authors： Moré JM,Voelker DR,Silveira LJ,Edwards MG,Chan ED,Bowler RP

更新日期：2010-10-25 00:00:00

abstract：BACKGROUND:This study was conducted in order to determine the prevalence of asthma and associated risk factors in the adult population of Karachi, Pakistan. METHODS:This multi-stage, cross-sectional survey was conducted from May 2014-August 2015; comprising 1629 adults in 75 randomly selected clusters in Karachi, Paki...

journal_title：BMC pulmonary medicine

authors： Razzaq S,Nafees AA,Rabbani U,Irfan M,Naeem S,Khan MA,Fatmi Z,Burney P

更新日期：2018-12-04 00:00:00

abstract：BACKGROUND:Pneumonia poses a significant burden to the U.S. health-care system. However, there are few data focusing on severe pneumonia, particularly cases of pneumonia associated with specialized care in intensive care units (ICU). METHODS:We used administrative and electronic medical record data from six integrated...

journal_title：BMC pulmonary medicine

authors： Storms AD,Chen J,Jackson LA,Nordin JD,Naleway AL,Glanz JM,Jacobsen SJ,Weintraub ES,Klein NP,Gargiullo PM,Fry AM

更新日期：2017-12-16 00:00:00

abstract：BACKGROUND:Skeletal muscle function dysfunction has been reported in patients with cystic fibrosis (CF). Studies so far showed inconclusive data whether reduced exercise capacity is related to intrinsic muscle dysfunction in CF. METHODS:Twenty patients with CF and 23 age-matched controls completed an incremental cardi...

journal_title：BMC pulmonary medicine

authors： Ruf K,Beer M,Köstler H,Weng AM,Neubauer H,Klein A,Platek K,Roth K,Beneke R,Hebestreit H

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:Omega-3 fatty acids, including alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and derivatives, play a key role in the resolution of inflammation. Higher intake has been linked to decreased morbidity in several diseases, though effects on respiratory diseases like COPD are...

journal_title：BMC pulmonary medicine

authors： Lemoine S CM,Brigham EP,Woo H,Hanson CK,McCormack MC,Koch A,Putcha N,Hansel NN

更新日期：2019-05-21 00:00:00

abstract：BACKGROUND:The tissue factor (TF)-dependent extrinsic pathway has been suggested to be a central mechanism by which the coagulation cascade is locally activated in the lungs of patients with acute lung injury and acute respiratory distress syndrome (ALI/ARDS) and thus represents an attractive target for therapeutic int...

journal_title：BMC pulmonary medicine

authors： Morris PE,Steingrub JS,Huang BY,Tang S,Liu PM,Rhode PR,Wong HC

更新日期：2012-02-16 00:00:00

abstract：BACKGROUND:The effectiveness of clinic-based pulmonary rehabilitation in advanced COPD is well established, but few data exist for less severe patients treated in alternative settings. The purpose of this study was to investigate whether a novel, community-based exercise program (CBE) was feasible and effective for pat...

journal_title：BMC pulmonary medicine

authors： Amin S,Abrazado M,Quinn M,Storer TW,Tseng CH,Cooper CB

更新日期：2014-08-04 00:00:00

abstract：BACKGROUND:US mentholated cigarette sales have increased considerably over 50 years. Preference for mentholated cigarettes is markedly higher in Black people. While menthol itself is not genotoxic or carcinogenic, its acute respiratory effects might affect inhalation of cigarette smoke. This possibility seems consisten...

journal_title：BMC pulmonary medicine

authors： Lee PN

更新日期：2011-04-18 00:00:00

abstract：BACKGROUND:Hyperoxia is common early in the course of resuscitation of critically ill patients. It has been associated with mortality in some, but not all, studies of cardiac arrest patients and other critically ill cohorts. Reasons for the inconsistency are unclear and may depend on unmeasured patient confounders, the...

journal_title：BMC pulmonary medicine

authors： Russell DW,Janz DR,Emerson WL,May AK,Bernard GR,Zhao Z,Koyama T,Ware LB

更新日期：2017-02-03 00:00:00

abstract：BACKGROUND:Telehealth and telemonitoring is an emerging area of study in people with cystic fibrosis (CF), with the potential of increasing access to care, and minimising infection control risks to patients without compromising their health outcomes. To date, limited evidence is available to support the use of teleheal...

journal_title：BMC pulmonary medicine

authors： Lang RL,Wilson C,Stockton K,Russell T,Johnston LM

更新日期：2019-01-24 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via the original article. ...

journal_title：BMC pulmonary medicine

authors： Pakhale S,Armstrong M,Holly C,Edjoc R,Gaudet E,Aaron S,Tasca G,Cameron W,Balfour L

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND:Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is the most common reason for the hospitalization and death of pulmonary patients. The use of antibiotics as adjuvant therapy for AECOPD, however, is still a matter of debate. METHODS:In this study, we searched the PubMed, EmBase, and Coch...

journal_title：BMC pulmonary medicine

authors： Zhang HL,Tan M,Qiu AM,Tao Z,Wang CH

更新日期：2017-12-12 00:00:00

abstract：BACKGROUND:Neurohumoral activation is present in COPD and might provide a link between pulmonary and systemic effects, especially cardiovascular disease. Because long acting inhaled β-agonists reduce hyperinflation, they could reduce sympathoexcitation by improving the inflation reflex. We aimed to evaluate if inhaled ...

journal_title：BMC pulmonary medicine

authors： Haarmann H,Mohrlang C,Tschiesner U,Rubin DB,Bornemann T,Rüter K,Bonev S,Raupach T,Hasenfuß G,Andreas S

更新日期：2015-04-30 00:00:00

abstract：BACKGROUND:Diagnosis of lower respiratory tract infections (LRTI) depends on the presence of clinical, radiological and microbiological findings. Endotracheal suction aspirate (ETSA) is the commonest respiratory sample sent for culture from intubated patients. Very few studies have compared quantitative and semi-quanti...

journal_title：BMC pulmonary medicine

authors： Rattani S,Farooqi J,Jabeen G,Chandio S,Kash Q,Khan A,Jabeen K

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND:Pulmonary alveolar proteinosis (PAP) is a rare lung disease characterized by accumulation of phospholipoproteinaceous material in the alveoli. The presentation is nonspecific but typically includes dyspnea; the spectrum of disease includes rapidly progressive hypoxic respiratory failure. Whole lung lavage (W...

journal_title：BMC pulmonary medicine

authors： Boyce DSK,Lee JW,Shah P,Freeman JH,Aboudara MC,Hostler DC

更新日期：2019-03-12 00:00:00

abstract：BACKGROUND:Activins are members of the TGF-ß superfamily of growth factors. First, we identified by expression array screening that activin-B and follistatin are upregulated in human idiopathic pulmonary fibrosis (IPF). Next, we wanted to clarify their specific role in lung fibrosis formation. METHODS:We used specific...

journal_title：BMC pulmonary medicine

authors： Myllärniemi M,Tikkanen J,Hulmi JJ,Pasternack A,Sutinen E,Rönty M,Leppäranta O,Ma H,Ritvos O,Koli K

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:CHCHD2 was identified a novel cell migration-promoting gene, which could promote cell migration and altered cell adhesion when ectopically overexpressed in NIH3T3 fibroblasts, and it was identified as a protein necessary for OxPhos function as well. However, the clinic relevance of CHCHD2 expression in NSCLC...

journal_title：BMC pulmonary medicine

authors： Yin X,Xia J,Sun Y,Zhang Z

更新日期：2020-02-13 00:00:00

abstract：BACKGROUND:Dose intensity and dose density of first line Platinum and Etoposide (PE) do not influence Overall Survival (OS) of Small Cell Lung Cancer (SCLC) patients. The effect of treatment length, however, remains unclear. Current guidelines recommend treating beyond 4 cycles -up to 6-, in patients that respond to an...

journal_title：BMC pulmonary medicine

authors： Sallam M,Wong H,Escriu C

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Selection bias is a systematic error in epidemiologic studies that may seriously distort true measures of associations between exposure and disease. Observational studies are highly susceptible to selection bias, and researchers should therefore always examine to what extent selection bias may be present in ...

journal_title：BMC pulmonary medicine

authors： Johannessen A,Verlato G,Benediktsdottir B,Forsberg B,Franklin K,Gislason T,Holm M,Janson C,Jögi R,Lindberg E,Macsali F,Omenaas E,Real FG,Saure EW,Schlünssen V,Sigsgaard T,Skorge TD,Svanes C,Torén K,Waatevik M,Nils

更新日期：2014-04-16 00:00:00

abstract：BACKGROUND:The use of extracorporeal membrane oxygenation (ECMO) in awake, spontaneously breathing and non-intubated patients (awake ECMO) may be a novel therapeutic strategy for severe acute respiratory distress syndrome (ARDS) patients. The purpose of this study is to assess the feasibility and safety of awake ECMO i...

journal_title：BMC pulmonary medicine

authors： Xia J,Gu S,Li M,Liu D,Huang X,Yi L,Wu L,Fan G,Zhan Q

更新日期：2019-12-09 00:00:00

abstract：BACKGROUND:Pseudomonas aeruginosa infections are associated with progressive life threatening decline of lung function in cystic fibrosis sufferers. Growth of Ps. aeruginosa releases a "grape-like" odour that has been identified as the microbial volatile organic compound 2-aminoacetophenone (2-AA). METHODS:We investig...

journal_title：BMC pulmonary medicine

authors： Scott-Thomas AJ,Syhre M,Pattemore PK,Epton M,Laing R,Pearson J,Chambers ST

更新日期：2010-11-07 00:00:00

abstract：BACKGROUND:Relationships between low forced vital capacity (FVC), and morbidity have previously been studied but there are no data available for the Caribbean population. This study assessed the association of low FVC with risk factors, health variables and socioeconomic status in a community-based study of the Trinida...

journal_title：BMC pulmonary medicine

authors： Sakhamuri S,Lutchmansingh F,Simeon D,Conyette L,Burney P,Seemungal T

更新日期：2019-03-14 00:00:00

abstract：BACKGROUND:A recent method determines regional gas flow of the lung by electrical impedance tomography (EIT). The aim of this study is to show the applicability of this method in a porcine model of mechanical ventilation in healthy and diseased lungs. Our primary hypothesis is that global gas flow measured by EIT can b...

journal_title：BMC pulmonary medicine

authors： Bodenstein M,Boehme S,Bierschock S,Vogt A,David M,Markstaller K

更新日期：2014-04-29 00:00:00