Fatty Acid-Binding Protein 4-An "Inauspicious" Adipokine-In Serum and Urine of Post-Partum Women with Excessive Gestational Weight Gain and Gestational Diabetes Mellitus.

abstract：BACKGROUND:We investigated the associations between v-Raf murine sarcoma viral oncogene homolog B1 (BRAFV600E, henceforth BRAF) and v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations and colorectal cancer (CRC) prognosis, using The Cancer Genome Atlas (TCGA) and the Gene Expression Omnibus (GSE39582)...

journal_title：Journal of clinical medicine

authors： Lee JH,Ahn J,Park WS,Choe EK,Kim E,Shin R,Heo SC,Jung S,Kim K,Chai YJ,Chae H

更新日期：2019-01-17 00:00:00

abstract：:Antibiotic treatment in paediatric rhinosinusitis is still a matter of debate, as the current guidelines have been drafted mainly based on clinical studies published before 2013. Recent modifications in the epidemiological basis of the disease might mean that current treatments are not completely adequate considering ...

journal_title：Journal of clinical medicine

authors： Torretta S,Drago L,Marchisio P,Gaini L,Guastella C,Moffa A,Rinaldi V,Casale M,Pignataro L

更新日期：2019-08-03 00:00:00

abstract：:The aim of this article is to investigate pathological subjects from a population through different physical factors. To achieve this, particle swarm optimization (PSO) and K-means (KM) clustering algorithms have been combined (PSO-KM). Datasets provided by the literature were divided into three clusters based on age ...

journal_title：Journal of clinical medicine

authors： Sari M,Tuna C,Akogul S

更新日期：2018-03-28 00:00:00

abstract：PURPOSE:Evaluating the effects of cibinetide in diabetic macular edema (DME). METHODS:Phase 2 trial. Naïve patients with >400 µm central retinal thickness (CRT) DME in one/both eyes were recruited (May 2016-April 2017) at the Belfast Health and Social Care Trust. The study eye was that with best vision and lowest CRT....

journal_title：Journal of clinical medicine

authors： Lois N,Gardner E,McFarland M,Armstrong D,McNally C,Lavery NJ,Campbell C,Kirk RI,Bajorunas D,Dunne A,Cerami A,Brines M

更新日期：2020-07-14 00:00:00

abstract：:Pigmented villonodular synovitis (PVNS) of the ankle is a very rare, locally aggressive, proliferative disorder. Although surgical excision represents the standard curative treatment, the PVNS relapse rate is high. We present our study of five young athletes (range 20-36 years) with a histopathological diagnosis of PV...

journal_title：Journal of clinical medicine

authors： Iakovou I,Symeonidis P,Kotrotsios D,Giannoula E,Sachpekidis C

更新日期：2020-02-22 00:00:00

abstract：:Permanent hypoparathyroidism, a feared thyroidectomy complication, leads to significant patient morbidity, medical treatment, and monitoring. This study explores whether preoperative high-dose vitamin D loading decreases the incidence of permanent hypoparathyroidism. In a subgroup analysis, the study examines the pred...

journal_title：Journal of clinical medicine

authors： Kannan T,Foster Y,Ho DJ,Gelzinnis SJ,Merakis M,Balogh ZJ,Wynne K,Bendinelli C

更新日期：2021-01-24 00:00:00

abstract：:This study proposes a method for measuring the volumetric change of alveolar bone after dental implant surgery using computed tomography (CT). A total of 40 implants in 20 patients (15 males and 5 females) were selected. The types of implants used were group 1: 24 CMI IS-II Active implants (Neobiotech Co., Seoul, Repu...

journal_title：Journal of clinical medicine

authors： Lim YW,Lim YJ,Kim B,Lee SP

更新日期：2020-04-24 00:00:00

abstract：BACKGROUND:Patients with diabetic kidney disease (DKD) are at higher risk of hypoglycemia than diabetic patients without DKD. We aimed to investigate the temporal trends of severe hypoglycemia in advanced DKD patients transitioning to dialysis and examine risk factors associated with severe hypoglycemia. We also invest...

journal_title：Journal of clinical medicine

authors： Hsiao CC,Tu HT,Lin CH,Chen KH,Yeh YH,See LC

更新日期：2019-03-27 00:00:00

abstract：:Robust early prediction of clinical outcomes in Parkinson's disease (PD) is paramount for implementing appropriate management interventions. We propose a method that uses the baseline MRI, measuring diffusion parameters from multiple parcellated brain regions, to predict the 2-year clinical outcome in Parkinson's dise...

journal_title：Journal of clinical medicine

authors： Tsai CC,Lin YC,Ng SH,Chen YL,Cheng JS,Lu CS,Weng YH,Lin SH,Chen PY,Wu YM,Wang JJ

更新日期：2020-02-28 00:00:00

abstract：BACKGROUND:Although aldosterone has been demonstrated to induce left ventricular (LV) hypertrophy not only in primary aldosteronism but also in primary hypertension (HT), it can be affected by multiple factors, including age, and the effect of aldosterone on LV function is controversial. This study was to investigate t...

journal_title：Journal of clinical medicine

authors： Park SM,Kim MN,Kim S,Shim WJ

更新日期：2019-07-17 00:00:00

abstract：:Hemorrhagic strokes account for half of all strokes seen in children, and the etiologies of these hemorrhagic strokes differ greatly from those seen in adult patients. This review gives an overview about incidence and etiologies as well as presentation of children with intracerebral hemorrhage and with differential di...

journal_title：Journal of clinical medicine

authors： Sporns PB,Psychogios MN,Fullerton HJ,Lee S,Naggara O,Boulouis G

更新日期：2020-05-18 00:00:00

abstract：:Schizophrenia is a multifactorial disease associated with widespread cognitive impairment. Although cognitive deficits are one of the factors most strongly associated with functional impairment in schizophrenia (SZ), current treatment strategies hardly tackle these impairments. To develop more efficient treatment stra...

journal_title：Journal of clinical medicine

authors： Mallet J,Le Strat Y,Dubertret C,Gorwood P

更新日期：2020-01-25 00:00:00

abstract：:Children are susceptible to a variety of respiratory infections. Wheezing is a common sign presented by children with respiratory infections. Asthma, bronchiolitis, and bronchitis are common causes of childhood wheezing disease (CWD) and are regarded as overlapping disease spectra. Macrolides are common antimicrobial ...

journal_title：Journal of clinical medicine

authors： Lin CY,Yeh TL,Liu SJ,Lin HH,Cheng YJ,Hung HH,Tsai MC,Liu JM,Lei WT

更新日期：2018-11-09 00:00:00

abstract：:Pain is the main impetus for osteoarthritis (OA) patients to seek healthcare including joint replacement. The pain experience in OA is heterogeneous and affected by factors across multiple domains-peripheral, psychological, and neurological. This indicates the existence of homogenous subgroups/phenotypes within OA pat...

journal_title：Journal of clinical medicine

authors： Pan F,Tian J,Munugoda IP,Graves S,Lorimer M,Cicuttini F,Jones G

更新日期：2020-02-27 00:00:00

abstract：:This study explored the perspectives and experiences of breast cancer patients and medical oncologists with regards to participation in a lifestyle intervention at a tertiary cancer treatment center. A thematic approach was used to understand the context within which a lifestyle intervention was recommended and experi...

journal_title：Journal of clinical medicine

authors： Balneaves LG,Truant TLO,Van Patten C,Kirkham AA,Waters E,Campbell KL

更新日期：2020-08-31 00:00:00

abstract：:Coronavirus disease 2019 (COVID-19) is a pandemic viral disease originated in Wuhan, China, in December 2019, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The severe form of the disease is often associated with acute respiratory distress syndrome (ARDS), and most critically ill patients ...

journal_title：Journal of clinical medicine

authors： Gardin C,Ferroni L,Chachques JC,Zavan B

更新日期：2020-08-26 00:00:00

abstract：BACKGROUND:Hyponatraemia is associated with increased morbidity, increased mortality and is frequently hospital-acquired due to inappropriate administration of hypotonic fluids. Despite several attempts to minimise the risk, knowledge is lacking as to whether inappropriate prescribing practice continues to be a concern...

journal_title：Journal of clinical medicine

authors： Sindahl P,Overgaard-Steensen C,Wallach-Kildemoes H,De Bruin ML,Leufkens HG,Kemp K,Gardarsdottir H

更新日期：2020-08-29 00:00:00

abstract：:Background: Corticosteroids are commonly prescribed for autoimmune conditions, but their impact on preventable hospitalization rates is unclear. This study sought to investigate the effect of corticosteroid use on hospitalization for ambulatory care sensitive conditions among Taiwanese patients with ankylosing spondyl...

journal_title：Journal of clinical medicine

authors： Wallace BI,Harris CA,Wang L,Liu M,Chen JS,Kuo CF,Chung KC

更新日期：2019-05-07 00:00:00

abstract：:Pediatric cancer survivors are at increased risk for psychological distress. We sought to understand the severity and symptoms' co-occurrence among pediatric survivors compared to controls by rating both self- and parent-reported symptomatology. Forty survivors (22 males; mean age at study time: 12.9 years) participat...

journal_title：Journal of clinical medicine

authors： Barone R,Gulisano M,Cannata E,Padalino S,Saia F,Maugeri N,Pettinato F,Lo Nigro L,Casabona A,Russo G,Di Cataldo A,Rizzo R

更新日期：2020-10-27 00:00:00

abstract：:Mitochondrial neurogastrointestinal encephalomyopathy (MNGIE-MTDPS1) is a devastating autosomal recessive disorder due to mutations in TYMP, which cause a loss of function of thymidine phosphorylase (TP), nucleoside accumulation in plasma and tissues, and mitochondrial dysfunction. The clinical picture includes progre...

journal_title：Journal of clinical medicine

authors： Filosto M,Cotti Piccinelli S,Caria F,Gallo Cassarino S,Baldelli E,Galvagni A,Volonghi I,Scarpelli M,Padovani A

更新日期：2018-10-26 00:00:00

abstract：:Acute kidney injury (AKI) is characterized by an acute decrease in renal function that can be multifactorial in its origin and is associated with complex pathophysiological mechanisms. In the short term, AKI is associated with an increased length of hospital stay, health care costs, and in-hospital mortality, and its ...

journal_title：Journal of clinical medicine

authors： Gameiro J,Fonseca JA,Outerelo C,Lopes JA

更新日期：2020-06-02 00:00:00

abstract：:To bridge the translational gap between recent discoveries of distinct molecular phenotypes of pancreatic cancer and tangible improvements in patient outcome, there is an urgent need to develop strategies and tools informing and improving the clinical decision process. Radiomics and machine learning approaches can off...

journal_title：Journal of clinical medicine

authors： Kaissis GA,Ziegelmayer S,Lohöfer FK,Harder FN,Jungmann F,Sasse D,Muckenhuber A,Yen HY,Steiger K,Siveke J,Friess H,Schmid R,Weichert W,Makowski MR,Braren RF

更新日期：2020-03-07 00:00:00

abstract：:In emergency departments, the most common cause of death associated with suspected infected patients is sepsis. In this study, deep learning algorithms were used to predict the mortality of suspected infected patients in a hospital emergency department. During January 2007 and December 2013, 42,220 patients considered...

journal_title：Journal of clinical medicine

authors： Perng JW,Kao IH,Kung CT,Hung SC,Lai YH,Su CM

更新日期：2019-11-07 00:00:00

abstract：:In the grey zone of testosterone levels between 8 and 12 nmol/L, the usefulness of therapy is controversial; as such, markers of tissue action of androgens may be helpful in adjusting clinical decisions. To better understand the effect of the hypothalamic-pituitary-testicular axis on male accessory secretion, we perfo...

journal_title：Journal of clinical medicine

authors： Grande G,Vincenzoni F,Mancini F,Barrachina F,Giampietro A,Castagnola M,Urbani A,Oliva R,Milardi D,Pontecorvi A

更新日期：2019-12-03 00:00:00

abstract：:Acute retinal necrosis (ARN) is a rare viral endophthalmitis, and human herpesvirus is the principal pathogen. Early diagnosis and treatment are critical to avoid visual impairment by ARN, and pars plana vitrectomy (PPV) is required in advanced cases. In this study, we evaluated the transition of viral load in ocular ...

journal_title：Journal of clinical medicine

authors： Sato T,Yamamoto W,Tanaka A,Shimazaki H,Sugita S,Kaburaki T,Takeuchi M

更新日期：2020-04-22 00:00:00

abstract：:Hemophilia is the most common of the severe bleeding disorders and if not properly managed since early infancy can lead to chronic disease and lifelong disabilities. However, it enjoys the most efficacious and safe treatment among the most prevalent monogenic disorders. Hemophilia should be considered in the neonatal ...

journal_title：Journal of clinical medicine

authors： Bertamino M,Riccardi F,Banov L,Svahn J,Molinari AC

更新日期：2017-05-19 00:00:00

abstract：:Limited evidence is available comparing the differences between pre-operative and post-operative 3D implant positions from the viewpoint of prosthetics. We aimed to investigate the differences between preplanned positions of virtual provisional restorations and their actual positions following fully guided single-impl...

journal_title：Journal of clinical medicine

authors： Oh KC,Kim JH,Woo CW,Moon HS

更新日期：2019-04-11 00:00:00

abstract：:Sarcopenia is defined as a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength. It has been identified as one of the most common comorbidities associated with femoral neck fracture (FNF). The aim of this review was to evaluate the impact of physical therapy on FNF patients' ...

journal_title：Journal of clinical medicine

authors： Avola M,Mangano GRA,Testa G,Mangano S,Vescio A,Pavone V,Vecchio M

更新日期：2020-09-26 00:00:00

abstract：:Most studies on well-being during the COVID-19 pandemic have focused on the mental health of the general population; far less attention has been given to more specific populations, such as patients with mental illness. Indeed, it is important to examine the psychiatric population, given its vulnerability. The present ...

journal_title：Journal of clinical medicine

authors： Burrai J,Roma P,Barchielli B,Biondi S,Cordellieri P,Fraschetti A,Pizzimenti A,Mazza C,Ferracuti S,Giannini AM

更新日期：2020-11-23 00:00:00

abstract：:Minimal residual disease evaluation refers to a series of molecular and immunophenotypical techniques aimed at detecting submicroscopic disease after therapy. As such, its application in acute myeloid leukemia has greatly increased our ability to quantify treatment response, and to determine the chemosensitivity of th...

journal_title：Journal of clinical medicine

authors： Mosna F,Capelli D,Gottardi M

更新日期：2017-06-03 00:00:00