Abstract:
:In emergency departments, the most common cause of death associated with suspected infected patients is sepsis. In this study, deep learning algorithms were used to predict the mortality of suspected infected patients in a hospital emergency department. During January 2007 and December 2013, 42,220 patients considered in this study were admitted to the emergency department due to suspected infection. In the present study, a deep learning structure for mortality prediction of septic patients was developed and compared with several machine learning methods as well as two sepsis screening tools: the systemic inflammatory response syndrome (SIRS) and quick sepsis-related organ failure assessment (qSOFA). The mortality predictions were explored for septic patients who died within 72 h and 28 days. Results demonstrated that the accuracy rate of deep learning methods, especially Convolutional Neural Network plus SoftMax (87.01% in 72 h and 81.59% in 28 d), exceeds that of the other machine learning methods, SIRS, and qSOFA. We expect that deep learning can effectively assist medical staff in early identification of critical patients.
journal_name
J Clin Medjournal_title
Journal of clinical medicineauthors
Perng JW,Kao IH,Kung CT,Hung SC,Lai YH,Su CMdoi
10.3390/jcm8111906subject
Has Abstractpub_date
2019-11-07 00:00:00issue
11issn
2077-0383pii
jcm8111906journal_volume
8pub_type
杂志文章abstract::Background: Urinary calprotectin is a novel biomarker that distinguishes between intrinsic or prerenal acute kidney injury (AKI) in different studies. However, these studies were based on different populations and different AKI criteria. We evaluated the diagnostic accuracy of urinary calprotectin and compared its dia...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm8010074
更新日期:2019-01-10 00:00:00
abstract::Sleep bruxism (SB) is a masticatory muscle activity during sleep that is characterized as rhythmic (phasic) or non-rhythmic (tonic). The recent hypothesis on the etiology of SB supports the role of the central and autonomic nervous systems. Therefore, in this study, we aimed to assess the intensity of SB in patients w...
journal_title:Journal of clinical medicine
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更新日期:2018-10-05 00:00:00
abstract:BACKGROUND:Heart failure with preserved ejection fraction (HFpEF) remains an ongoing therapeutic and diagnostic challenge to date. In this study we aimed for an analysis of the diagnostic potential of four novel cardiovascular biomarkers, GDF-15, H-FABP, sST2, and suPAR in HFpEF patients compared to controls as well as...
journal_title:Journal of clinical medicine
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doi:10.3390/jcm9041130
更新日期:2020-04-15 00:00:00
abstract::The Scapula Reposition Test (SRT) is proposed to determine if a relationship exists between scapular dyskinesis and shoulder pathology. The purpose of this study was to evaluate intra-rater and inter-rater reliability of the SRT in subjects with rotator cuff tendinopathy and scapular dyskinesis. In addition, we compar...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9010080
更新日期:2019-12-28 00:00:00
abstract::This study investigated physical activity (PA) and sedentary time (SED) in relation to hippocampal gray matter volume (GMV) in pediatric overweight/obesity. Ninety-three children (10 ± 1 year) were classified as overweight, obesity type I, or type II-III. PA was assessed with non-dominant wrist accelerometers. GMV was...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9041080
更新日期:2020-04-10 00:00:00
abstract::An improvement in negative symptoms and a reduction in the number of visits to the emergency department have been reported in a problem solving based psychoeducational group intervention (PE) for adolescents with psychosis relative to a nonstructured group (NS). One of the factors that may play a role on the response ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8122108
更新日期:2019-12-02 00:00:00
abstract::Patients with chronic obstructive pulmonary disease (COPD), asthma and interstitial lung diseases (ILD) frequently suffer from cardiovascular comorbidities (CVC). Exercise training is a cornerstone intervention for the management of these conditions, however recommendations on tailoring programmes to patients sufferin...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
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更新日期:2019-09-13 00:00:00
abstract::Pancreatic pathology, comprising acute and chronic pancreatitis, autoimmune pancreatitis and pancreatic neoplasms, primarily presents with gastrointestinal symptoms and signs; however, it is well recognized that it can also associate a wide range of extra-digestive features. Among these systemic manifestations, cutane...
journal_title:Journal of clinical medicine
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doi:10.3390/jcm9082611
更新日期:2020-08-12 00:00:00
abstract::Haemoglobinopathies are common monogenic disorders with diverse clinical manifestations, partly attributed to the influence of modifier genes. Recent years have seen enormous growth in the amount of genetic data, instigating the need for ranking methods to identify candidate genes with strong modifying effects. Here, ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8111927
更新日期:2019-11-09 00:00:00
abstract::There is a lack of evidence or societal guidelines regarding the utility of fibrinogen monitoring during thrombolysis. The purpose of our study was to investigate the current use of monitoring fibrinogen levels during thrombolysis. A voluntary, anonymous online survey was sent to all physician members of the Society o...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm7050111
更新日期:2018-05-10 00:00:00
abstract::Epistaxis is a common debilitating manifestation in hereditary hemorrhagic telangiectasia (HHT), due to mucocutaneous telangiectases. The epistaxis can be difficult to control despite available treatments. Dysregulated angiogenesis has been shown to be associated with telangiectases formation. Topical propranolol has ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9103130
更新日期:2020-09-28 00:00:00
abstract::Microbial contamination could compromise the stability of dental implants increasing the risk of inflammatory reactions in the surrounding soft tissues. In this human, randomized, double-blind, clinical study, the presence of Porphyromonas gingivalis on the healing abutment and the inflammatory infiltrate surrounding ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9010284
更新日期:2020-01-20 00:00:00
abstract::Central serous chorioretinopathy (CSC) is a complex and not entirely understood retinal disease. The aim of our research was to describe a novel optical coherence tomography (OCT) finding named "choroidal rift", which may be identified in the choroid of eyes with CSC. We collected data from 357 patients (488 eyes) wit...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9072260
更新日期:2020-07-16 00:00:00
abstract::The pathophysiology of cardiogenic shock (CS) varies depending on its etiology, which may lead to different hemodynamic profiles (HP) and may help tailor therapy. We aimed to assess the HP of CS patients according to their etiologies of acute myocardial infarction (AMI) and acute decompensated chronic heart failure (A...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9113384
更新日期:2020-10-22 00:00:00
abstract::Spinal disorders and associated interventions are costly in the United States, putting them in the limelight of economic analyses. The Patient-Reported Outcomes Measurement Information System Global Health Survey (PROMIS-GHS) requires mapping to other surveys for economic investigation. Previous studies have proposed ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8101506
更新日期:2019-09-20 00:00:00
abstract::Von Hippel-Lindau (VHL), is a rare autosomal dominant inherited cancer in which the lack of VHL protein triggers the development of multisystemic tumors such us retinal hemangioblastomas (HB), CNS-HB, and clear cell renal cell carcinoma (ccRCC). ccRCC ranks third in terms of incidence and first in cause of death. Stan...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9092740
更新日期:2020-08-25 00:00:00
abstract::Postoperative atrial fibrillation (POAF) is linked with increased morbidity, mortality rate and financial liability. About 20-50% of patients experience POAF after coronary artery bypass graft (CABG) surgery. Numerous review articles and meta-analyses have investigated links between patient clinical risk factors, demo...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9041139
更新日期:2020-04-16 00:00:00
abstract::To bridge the translational gap between recent discoveries of distinct molecular phenotypes of pancreatic cancer and tangible improvements in patient outcome, there is an urgent need to develop strategies and tools informing and improving the clinical decision process. Radiomics and machine learning approaches can off...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9030724
更新日期:2020-03-07 00:00:00
abstract::The widespread epidemic of obesity and type 2 diabetes (T2D), suggests that both disorders are closely linked. Several pre-clinical and clinical studies have showed that adipose-derived mesenchymal stem cells (ASC) transplantation is efficient and safe. Moreover, scientists have already highlighted the therapeutic cap...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm8060765
更新日期:2019-05-30 00:00:00
abstract:BACKGROUND:Population aging poses unprecedented demands on the healthcare system. There is also a scarcity of evidence on self-care intervention to improve objective measures of morbidity and aging-associated functional and physiological measures in a low-income multi-ethnic population setting. METHODS:We conducted a ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9030885
更新日期:2020-03-24 00:00:00
abstract::Cholangiocarcinoma (CCA) arises from the biliary tract epithelium and accounts for 10-15% of all hepatobiliary malignancies. Depending on anatomic location, CCA is classified as intrahepatic (iCCA), perihilar (pCCA) and distal (dCCA). The best treatment option for pCCA is liver resection and when a radical oncological...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9051353
更新日期:2020-05-05 00:00:00
abstract::Sarcopenia is related to adverse outcomes in various populations. However, little is known about the prevalence of sarcopenia in polytrauma patients. Identifying the number of patients at risk of adverse outcome will increase awareness to prevent further loss of muscle mass. We utilized data from a regional prospectiv...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9072046
更新日期:2020-06-29 00:00:00
abstract::Coronavirus disease 2019 (COVID-19), due to the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has become an epidemiological threat and a worldwide concern. SARS-CoV-2 has spread to 210 countries worldwide and more than 6,500,000 confirmed cases and 384,643 deaths have been reported, while the number of...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9061753
更新日期:2020-06-05 00:00:00
abstract:AIM:This study examined the fertility performance of women after combined hysterolaparoscopic surgical management of endometriosis. Design: This study is a hospital-based retrospective review. MATERIALS AND METHODS:Data collected from the records of all patients presented with endometriosis-related infertility using a...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9020507
更新日期:2020-02-13 00:00:00
abstract::Since the discovery of the causal association between human papillomavirus (HPV) and cervical cancer, efforts to develop an effective prophylactic vaccine to prevent high-risk HPV infections have been at the forefront of modern medical research. HPV causes 530,000 cervical cancer cases worldwide, which is the second m...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm4040614
更新日期:2015-04-03 00:00:00
abstract::Sarcopenia is defined as a syndrome characterized by progressive and generalized loss of skeletal muscle mass and strength. It has been identified as one of the most common comorbidities associated with femoral neck fracture (FNF). The aim of this review was to evaluate the impact of physical therapy on FNF patients' ...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9103115
更新日期:2020-09-26 00:00:00
abstract::Neuroendocrine breast cancer (NEBC) is a rare histotype of breast carcinoma that presents, in most cases, positive hormone receptors and negative HER2. Indeed, the analysis of gene expression profiles revealed that NEBC belongs mainly to the luminal subtype. Cases of HER2-positive and triple-negative NEBC are rare. Th...
journal_title:Journal of clinical medicine
pub_type: 杂志文章,评审
doi:10.3390/jcm9051452
更新日期:2020-05-13 00:00:00
abstract::Continuous positive airway pressure (CPAP) is the most efficient treatment of obstructive sleep apnea (OSA). Little is known about the impact of spousal relationship profiles on CPAP adherence. We aimed to identify clusters of couples of OSA patients, and their association with CPAP adherence 120 days after CPAP initi...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9061658
更新日期:2020-06-01 00:00:00
abstract::Nocturnal (night) eating syndrome and sleep-related eating disorder have common characteristics, but are considered to differ in their level of consciousness during eating behavior and recallability. To date, there have been no large population-based studies determining their similarities and differences. We conducted...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm9041243
更新日期:2020-04-24 00:00:00
abstract:BACKGROUND:Despite growing social acceptance, the LGBTQ population continues to face barriers to healthcare including fear of stigmatization by healthcare providers, and providers' lack of knowledge about LGBTQ-specific health issues. This analysis focuses on the assessment of quantitative and qualitative responses fro...
journal_title:Journal of clinical medicine
pub_type: 杂志文章
doi:10.3390/jcm6100093
更新日期:2017-10-07 00:00:00