New Insights Regarding Genetic Aspects of Childhood Obesity: A Minireview.

abstract：:Autoimmune Congenital Heart Block (CHB) is an immune-mediated disease due to transplacental passage of circulating anti-Ro/SSA and anti-La/SSB autoantibodies. It occurs in 2% of anti-Ro/SSA-exposed pregnancies, and recurrence rate is nine times higher in subsequent pregnancies. Aim of this review is to identify biomar...

journal_title：Frontiers in pediatrics

authors： De Carolis S,Garufi C,Garufi E,De Carolis MP,Botta A,Tabacco S,Salvi S

更新日期：2020-12-22 00:00:00

abstract：:There is a growing awareness of the role that increased pulmonary vascular resistance (PVR) plays in many pathologies; therefore, assessment of pulmonary artery pressure (PAP) is an increasingly requested investigation in the critical care environment. This article will go through the basic concepts regarding PAP and ...

journal_title：Frontiers in pediatrics

authors： Skinner GJ

更新日期：2017-09-04 00:00:00

abstract：:Pediatrics, among all the branches of medicine, is a sector not particularly affected by a high number of claims. Nevertheless, the economic value of the compensation is significantly high, for example, in cases of children who suffered multiple disabilities following perinatal lesions with a long life expectancy. In ...

journal_title：Frontiers in pediatrics

authors： Bertozzi G,Maglietta F,Baldari B,Besi L,Torsello A,Di Gioia CRT,Sessa F,Aromatario M,Cipolloni L

更新日期：2020-05-27 00:00:00

abstract：OBJECTIVE:We investigated the relationship between influenza seasonality and outcome of very low birth weight infants (VLBWI) in a large observational cohort study of the German Neonatal Network. MATERIALS AND METHODS:Within the observational period (July 2009 until December 2014), five influenza seasons occurred (mea...

journal_title：Frontiers in pediatrics

authors： Härtel C,Humberg A,Viemann D,Stein A,Orlikowsky T,Rupp J,Kopp MV,Herting E,Göpel W

更新日期：2016-11-30 00:00:00

abstract：:Chronic thromboembolic pulmonary hypertension is a potentially curable form of pre-capillary pulmonary hypertension (PH) resulting from incomplete resolution of pulmonary thromboemboli. We describe an 11-year-old boy with homozygous sickle cell disease with an indwelling catheter found to have severe PH on routine scr...

journal_title：Frontiers in pediatrics

authors： Spencer R,Valencia Villeda G,Takeda K,Rosenzweig EB

更新日期：2020-07-24 00:00:00

abstract：:Autosomal recessive polycystic kidney disease (ARPKD) is a rare monogenic disease with a severe phenotype often presenting prenatally or in early childhood. With its obligate renal and hepatic involvement, ARPKD is one of the most important indications for liver and/or kidney transplantation in childhood. Marked pheno...

journal_title：Frontiers in pediatrics

authors： Ebner K,Schaefer F,Liebau MC,ARegPKD Consortium.

更新日期：2017-02-16 00:00:00

abstract：:Like most specialties, pediatric surgery is becoming more complex, and changes to health systems have not always been in the best interests of trainees or their surgical teachers. This paper outlines four of the current challenges faced by training boards in pediatric surgery worldwide, and documents their implication...

journal_title：Frontiers in pediatrics

authors： Beasley SW

更新日期：2013-09-11 00:00:00

abstract：:Recent studies have demonstrated that gut microbiota development is influenced by human biogeographic factors such as race, ethnicity, diet, lifestyle or culture-specific variations, and other environmental influences. However, biogeographic variation in gut microbiota assembly remains largely unexplored in Latin Amer...

journal_title：Frontiers in pediatrics

authors： Chew C,Barros KV,Weffort VRS,Maranhão HS,Laranjeira M,Knol J,Roeselers G,de Morais MB

更新日期：2020-12-07 00:00:00

abstract：:Objective: In many patients with congenital heart disease (CHD) arterial blood flow to the arms is inhibited due to shunt surgery in infancy. This study investigates the handgrip strength of patients with CHD in regard to previous shunt procedures. Patients and Methods: Handgrip was evaluated in 424 patients with vari...

journal_title：Frontiers in pediatrics

authors： Müller J,Röttgers L,Neidenbach RC,Oberhoffer R,Ewert P,Hager A

更新日期：2018-09-06 00:00:00

abstract：:Introduction: Childhood growth is a sensitive marker of health. Animal studies show increased height and weight velocity in the presence of fungal as well as antibiotic supplement in feed. Human studies on early gut microbiota and anthropometrics have mainly focused on bacteria only and overweight, with diverging resu...

journal_title：Frontiers in pediatrics

authors： Schei K,Simpson MR,Avershina E,Rudi K,Øien T,Júlíusson PB,Underhill D,Salamati S,Ødegård RA

更新日期：2020-11-09 00:00:00

abstract：:The burden of severe hearing impairment is increasing with two-thirds of these hearing impaired people residing in developing countries. Newborn hearing screening helps to identify early, babies who need intervention in order to prevent future disability. Neither universal nor targeted hearing screening programme is a...

journal_title：Frontiers in pediatrics

authors： Labaeka AA,Tongo OO,Ogunbosi BO,Fasunla JA

更新日期：2018-07-16 00:00:00

abstract：:The burden of asthma in childhood is considerable worldwide, although some populations are much more affected than others. Many attempts have been made by different investigators to identify the factors that could predict asthma development or persistence in childhood. In this review, the relation between atopic sensi...

journal_title：Frontiers in pediatrics

authors： Moustaki M,Loukou I,Tsabouri S,Douros K

更新日期：2017-07-31 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disorder of the gastrointestinal tract associated with significant morbidity. While IBD occurs in genetically susceptible individuals, the etiology is multifactorial, involving environmental influences, intestinal dysbiosis, and altered immune respon...

journal_title：Frontiers in pediatrics

authors： Foster A,Jacobson K

更新日期：2013-11-06 00:00:00

abstract：:Chronic granulomatous disease (CGD) is an inherited, genetically heterogeneous disease characterized by defective phagocytic cell microbicidal function, leading to increased susceptibility to bacterial and fungal infections. CGD is caused by mutations in components of the nicotinamide adenine dinucleotide phosphate (N...

journal_title：Frontiers in pediatrics

authors： de Albuquerque JAT,Lima AM,de Oliveira Junior EB,Ishizuka EK,Aragão-Filho WC,Bengala Zurro N,Mayumi Chiba S,Fernandes FR,Condino-Neto A

更新日期：2019-09-27 00:00:00

abstract：:Deficiency of adenosine deaminase 2 (DADA2) is a monogenic form of systemic vasculopathy that often presents during early childhood. Linked to biallelic mutations in ADA2 (previously CECR1), DADA2 was initially described as a syndrome of recurrent fever, livedo racemosa, early-onset strokes, and peripheral vasculopath...

journal_title：Frontiers in pediatrics

authors： Lee PY

更新日期：2018-10-18 00:00:00

abstract：:The current study investigated the differences between intact and non-intact families in family processes, including systematic family functioning, parental behavioral control, parental psychological control, and parent-child relational qualities. The participants were 3,328 Secondary One students, with a mean age of ...

journal_title：Frontiers in pediatrics

authors： Shek DT,Xie Q,Lin L

更新日期：2015-01-29 00:00:00

abstract：:Background: Intussusception is a common abdominal emergency in infancy and childhood, and the recurrence rate is reported to be up to 20%. Numerous potential risk factors for recurrence have been reported, although some of them are still controversial. Objective: The present study was conducted to identify the risk fa...

journal_title：Frontiers in pediatrics

authors： Ye X,Tang R,Chen S,Lin Z,Zhu J

更新日期：2019-04-16 00:00:00

abstract：:Hypertension after kidney transplant is a frequent occurrence in pediatric patients. It is a risk factor for graft loss and contributes to the significant burden of cardiovascular disease (CVD) in this population. The etiology of posttransplant hypertension is multifactorial including donor factors, recipient factors,...

journal_title：Frontiers in pediatrics

authors： Charnaya O,Moudgil A

更新日期：2017-05-01 00:00:00

abstract：:Bronchial asthma is one of the most common chronic inflammatory diseases of the airways. In the pathogenesis of this disease, the interplay among the genes, intrinsic, and extrinsic factors are crucial. Various combinations of the involved factors determine and modify the final clinical phenotype/endotype of asthma. O...

journal_title：Frontiers in pediatrics

authors： Jesenak M,Zelieskova M,Babusikova E

更新日期：2017-07-24 00:00:00

abstract：:Asthma is the most frequent chronic disease in children, and its pathogenesis involves genetic, epigenetic, and environmental factors. The rapid rise in the prevalence of asthma registered over the last few decades has stressed the need to identify the environmental and modifiable factors associated with the developme...

journal_title：Frontiers in pediatrics

authors： Trambusti I,Nuzzi G,Costagliola G,Verduci E,D'Auria E,Peroni DG,Comberiati P

更新日期：2020-08-18 00:00:00

abstract：:Objective: To identify postnatal risk factors for bronchopulmonary dysplasia (BPD) development in preterm infants with gestational age ≤32 weeks. Methods: Seventy-two preterm infants(30 with BPD and 42 non-BPD controls) admitted in the neonatal intensive care unit (NICU) of the Children's Hospital of Soochow Universit...

journal_title：Frontiers in pediatrics

authors： Ding L,Wang H,Geng H,Cui N,Huang F,Zhu X,Zhu X

更新日期：2020-06-26 00:00:00

abstract：:Urolithiasis can affect all children even preschool ones. Diagnostic difficulties in the youngest children are due to the problems in locating pain and determining its character and severity. In keeping with the ALARA (As Low As Reasonably Achievable) protocol, the number of imaging tests possible to perform is very l...

journal_title：Frontiers in pediatrics

authors： Halinski A,Halinski A,Zaniew M,Kudliński B,Soltysiak J,Sobolewski B,Steyaert H

更新日期：2019-09-06 00:00:00

abstract：:Minimal residual disease (MRD) by multiparametric flow cytometry (MFC) has been recently shown as a strong and independent prognostic marker of relapse in pediatric AML (pedAML) when measured at specific time points during Induction and/or Consolidation therapy. Hence, MFC-MRD has the potential to refine the current s...

journal_title：Frontiers in pediatrics

authors： Buldini B,Maurer-Granofszky M,Varotto E,Dworzak MN

更新日期：2019-10-11 00:00:00

abstract：:Introduction: The pediatric perineal microbiomes inhabit a dynamic environment with changes related to diet, toileting habits, and hormonal development. We hypothesized that next-generation sequencing would reveal different perineal bacterial signatures associated with developmental milestones in premenstrual females....

journal_title：Frontiers in pediatrics

authors： Lucas EJ,Ching CB,Saraswat S,Dabdoub SM,Kumar PP,Justice SS

更新日期：2020-12-08 00:00:00

abstract：:In genome science, the advancement in high-throughput sequencing technologies and bioinformatics analysis is facilitating the better understanding of Mendelian and complex trait inheritance. Charting the genetic basis of complex diseases - including pediatric cancer, and interpreting huge amount of next-generation seq...

journal_title：Frontiers in pediatrics

authors： Manwar Hussain MR,Khan A,Ali Mohamoud HS

更新日期：2014-03-03 00:00:00

abstract：:Objective: To highlight severe adenovirus pneumonia in immunocompetent patients by analysis of severe adenovirus pneumonia associated with acute respiratory distress syndrome in whom extracorporeal membrane oxygenation (ECMO) support is required. Methods:Pediatric patients with adenovirus pneumonia and ECMO supports i...

journal_title：Frontiers in pediatrics

authors： Chen X,Lv J,Qin L,Zou C,Tang L

更新日期：2020-04-15 00:00:00

abstract：BACKGROUND:Studies suggest that children with congenital heart defects (CHD) are at risk for adverse intellectual functioning. However, factors related to lower intellectual functioning in this group are largely unknown. This study describes intellectual functioning in children with CHD in relation to severity of the h...

journal_title：Frontiers in pediatrics

authors： Ryberg C,Sunnegårdh J,Thorson M,Broberg M

更新日期：2016-11-17 00:00:00

abstract：:We describe a giant gastric phytobezoar in a child with repaired congenital esophageal atresia. At age two, a gastric interposition (pull-up) procedure was performed for severe and recurrent esophageal strictures. For 12 months post-gastric interposition, he experienced frequent respiratory illnesses requiring hospita...

journal_title：Frontiers in pediatrics

authors： Chacko A,Masters BI,Isles A

更新日期：2017-06-19 00:00:00

abstract：:In recent decades, new research into the developmental defects and pathophysiological basis of congenital diaphragmatic hernia (CDH) has revealed opportunities for the development of innovative therapies. Importantly, the use of animal models to represent this anomaly in the laboratory has resulted in the discovery of...

journal_title：Frontiers in pediatrics

authors： Chiu PP

更新日期：2014-04-29 00:00:00

abstract：:Background: Although WU polyomavirus (WU) and KI polyomavirus (KI) have been demonstrated to infect the human respiratory tract, it remains unclear if WU or KI cause human disease. We sought to further investigate the relationship between WU and KI infection and respiratory disease in a pediatric population with respi...

journal_title：Frontiers in pediatrics

authors： Hansen-Estruch C,Coleman KK,Thoon KC,Low JG,Anderson BD,Gray GC

更新日期：2018-08-17 00:00:00