New Insights into Congenital Diaphragmatic Hernia - A Surgeon's Introduction to CDH Animal Models.

abstract：:Introduction: Primary repair of esophageal atresia (EA) in infants with very low birth weight (VLBW) and extremely low birth weight (ELBW) has been widely performed in pediatric surgery. However, several studies have shown that complication rates in infants with VLBW are high. We hypothesize preterm children benefit f...

journal_title：Frontiers in pediatrics

authors： Ritz LA,Widenmann-Grolig A,Jechalke S,Bergmann S,von Schweinitz D,Lurz E,Hubertus J

更新日期：2020-11-17 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a chronic, immune-mediated, non-curable disease. The incidence of IBD appears to have risen over the last few decades especially in the pediatric age group. IBD usually presents with gastrointestinal symptoms, including abdominal pain, diarrhea, and bleeding per rectum but can also ...

journal_title：Frontiers in pediatrics

authors： El-Matary W,Bernstein CN

更新日期：2020-07-17 00:00:00

abstract：:Introduction: Decreased respiratory muscle strength in patients with cystic fibrosis (CF) may cause progressive exercise intolerance during cardiopulmonary exercise testing (CPET), and may contribute to the development of chronic respiratory insufficiency. The aim of this study is to evaluate exercise tolerance during...

journal_title：Frontiers in pediatrics

authors： Sovtic A,Minic P,Markovic-Sovtic G,Trajkovic GZ

更新日期：2018-09-04 00:00:00

abstract：:Dedicator of cytokinesis 8 (DOCK8) deficiency is an autosomal recessive, combined immunodeficiency within the spectrum of hyper-IgE syndromes. Epstein-Barr virus-positive lymphomatoid granulomatosis (LYG) (EBV + LYG) is a rare diagnosis and a previously unreported presentation of DOCK8 deficiency. A 10-year-old girl w...

journal_title：Frontiers in pediatrics

authors： Dimitriades VR,Devlin V,Pittaluga S,Su HC,Holland SM,Wilson W,Dunleavy K,Shah NN,Freeman AF

更新日期：2017-02-28 00:00:00

abstract：:Epstein-Barr virus-associated T/natural killer-cell lymphoproliferative diseases (EBV-T/NK-LPDs) are a group of rare diseases resulting from ectopic infection of T or natural killer (NK) lymphocytes with Epstein-Barr virus (EBV). EBV-T/NK-LPDs include chronic active EBV infection, EBV-associated hemophagocytic lymphoh...

journal_title：Frontiers in pediatrics

authors： Kimura H,Fujiwara S

更新日期：2019-01-04 00:00:00

abstract：:Maternal primary and non-primary cytomegalovirus (CMV) infection during pregnancy can result in in utero transmission to the developing fetus. Congenital CMV (cCMV) can result in significant morbidity, mortality or long-term sequelae, including sensorineural hearing loss, the most common sequela. As a leading cause of...

journal_title：Frontiers in pediatrics

authors： Lazzarotto T,Blázquez-Gamero D,Delforge ML,Foulon I,Luck S,Modrow S,Leruez-Ville M

更新日期：2020-01-31 00:00:00

abstract：:Objectives: Severe congenital neutropenia (SCN) is a primary immunodeficiency disease characterized by the early onset of recurrent infections and persistent severe neutropenia, with or without genetic defect. We aimed to study the different clinical features and hematological and bone marrow characteristics of patien...

journal_title：Frontiers in pediatrics

authors： Gong RL,Wu J,Chen TX

更新日期：2018-10-16 00:00:00

abstract：:Purpose of Review: A significant number of pregnancies are complicated by a fetus with a life-limiting diagnosis. As diagnoses are made earlier in the pregnancy, families experience anticipatory grief and are faced with navigating goals of care for a baby that has yet to be born. With the support of the care team, fam...

journal_title：Frontiers in pediatrics

authors： Cortezzo DE,Ellis K,Schlegel A

更新日期：2020-09-08 00:00:00

abstract：UNLABELLED:Pediatric acute encephalopathy (AE) was sometimes attributed to virus infection. However, viral infection does not always result in AE. The risk factors for developing infantile AE upon virus infection remain to be determined. Here, we report an infant with AE co-infected with human herpesvirus-6 (HHV-6) and...

journal_title：Frontiers in pediatrics

authors： Nakata K,Kashiwagi M,Masuda M,Shigehara S,Oba C,Murata S,Kase T,Komano JA

更新日期：2015-04-02 00:00:00

abstract：:Sickle cell disease (SCD) is a severe autosomal recessively inherited disorder of the red blood cell characterized by erythrocyte deformation caused by the polymerization of the abnormal hemoglobin, which leads to erythrocyte deformation and triggers downstream pathological changes. These include abnormal rheology, va...

journal_title：Frontiers in pediatrics

authors： Krishnamurti L

更新日期：2021-01-05 00:00:00

abstract：:Hypertension after kidney transplant is a frequent occurrence in pediatric patients. It is a risk factor for graft loss and contributes to the significant burden of cardiovascular disease (CVD) in this population. The etiology of posttransplant hypertension is multifactorial including donor factors, recipient factors,...

journal_title：Frontiers in pediatrics

authors： Charnaya O,Moudgil A

更新日期：2017-05-01 00:00:00

abstract：:Despite distinct epidemiology and outcomes, pediatric acute respiratory distress syndrome (PARDS) is often managed based on evidence extrapolated from treatment of adults. The impact of non-pulmonary processes on mortality as well as the lower mortality rate compared to adults with acute respiratory distress syndrome ...

journal_title：Frontiers in pediatrics

authors： Yehya N,Thomas NJ

更新日期：2016-05-13 00:00:00

abstract：:Autoimmune Congenital Heart Block (CHB) is an immune-mediated disease due to transplacental passage of circulating anti-Ro/SSA and anti-La/SSB autoantibodies. It occurs in 2% of anti-Ro/SSA-exposed pregnancies, and recurrence rate is nine times higher in subsequent pregnancies. Aim of this review is to identify biomar...

journal_title：Frontiers in pediatrics

authors： De Carolis S,Garufi C,Garufi E,De Carolis MP,Botta A,Tabacco S,Salvi S

更新日期：2020-12-22 00:00:00

abstract：:Background: Oral health is important for overall health of youth, although dental service utilization is lower than national goals. The purpose of the study was to identify sociodemographic and health behavioral characteristics of youth in the United States who reported having at least one dental visit in the past 12 ...

journal_title：Frontiers in pediatrics

authors： Chertok IRA,Chertok N,Haile ZT,Chavan B

更新日期：2018-05-04 00:00:00

abstract：:Isoflavones are dietary phytoestrogens commonly found in soy-based products. The widespread presence of isoflavones in soy infant formula and breast milk may have long-lasting effects on the development of sex hormone-sensitive organs like the skeleton. Animal early-life programming models are suitable for testing the...

journal_title：Frontiers in pediatrics

authors： Chin KY,Pang KL

更新日期：2020-09-11 00:00:00

abstract：:Bronchial asthma is one of the most common chronic inflammatory diseases of the airways. In the pathogenesis of this disease, the interplay among the genes, intrinsic, and extrinsic factors are crucial. Various combinations of the involved factors determine and modify the final clinical phenotype/endotype of asthma. O...

journal_title：Frontiers in pediatrics

authors： Jesenak M,Zelieskova M,Babusikova E

更新日期：2017-07-24 00:00:00

abstract：:Background: Early and non-invasive diagnosis of common diseases is of great importance in the care of preterm infants. We hypothesized that volatile organic compounds (VOC) can be successfully measured in the neonatal incubator atmosphere. Methods: This is a feasibility study to investigate whether the discrimination ...

journal_title：Frontiers in pediatrics

authors： Steinbach J,Goedicke-Fritz S,Tutdibi E,Stutz R,Kaiser E,Meyer S,Baumbach JI,Zemlin M

更新日期：2019-06-18 00:00:00

abstract：:Aim: The aim of this study was to present primary outcomes of autologous bone marrow mononuclear cell (BMMNC) transplantation to improve neurological sequelae in four children with intracranial hemorrhage (ICH) incidence during the neonatal period. Methods: GMFM88 and modified Ashworth score were used to assess motor ...

journal_title：Frontiers in pediatrics

authors： Liem NT,Huyen TL,Huong LT,Doan NV,Anh BV,Anh NTP,Tung DT

更新日期：2020-01-24 00:00:00

abstract：:Failure of statural growth is one of the major long-term sequelae of chronic kidney disease (CKD) in children. In recent years effective therapeutic strategies have become available that lead to evidence based practice recommendations. To assess the current growth performance of European children and adolescents with ...

journal_title：Frontiers in pediatrics

authors： Behnisch R,Kirchner M,Anarat A,Bacchetta J,Shroff R,Bilginer Y,Mir S,Caliskan S,Paripovic D,Harambat J,Mencarelli F,Büscher R,Arbeiter K,Soylemezoglu O,Zaloszyc A,Zurowska A,Melk A,Querfeld U,Schaefer F,and the 4C S

更新日期：2019-07-05 00:00:00

abstract：:Although antibiotics confer significant health benefits in treating or preventing bacterial infections, an accumulating wealth of evidence illustrates their detrimental effect on host-microbiota homeostasis, posing a serious menace to the global public health. In recent years, it is becoming evident that infants, who ...

journal_title：Frontiers in pediatrics

authors： Shekhar S,Petersen FC

更新日期：2020-10-15 00:00:00

abstract：:Cystic kidney diseases comprise a varied collection of hereditary disorders, where renal cysts comprise a major element of their pleiotropic phenotype. In pediatric patients, the term polycystic kidney disease (PKD) commonly refers to two specific hereditary diseases, autosomal recessive polycystic kidney disease (ARP...

journal_title：Frontiers in pediatrics

authors： Sweeney WE Jr,Avner ED

更新日期：2017-04-19 00:00:00

abstract：:Background: Primary carnitine deficiency (PCD) is attributed to a variation in the SLC22A5 (OCTN2) gene which encodes the key protein of the carnitine cycle, the OCTN2 carnitine transporter. PCD is typically identified in childhood by either hypoketotic hypoglycemia, or skeletal and cardiac myopathy. The aim of this s...

journal_title：Frontiers in pediatrics

authors： Zhou W,Li H,Huang T,Zhang Y,Wang C,Gu M

更新日期：2019-02-26 00:00:00

abstract：:Background and Objective: Mild hypospadias is a birth congenital condition characterized by the relocation of the male urethral meatus from its typical anatomical position near the tip of the glans penis, to a lower ventral position up to the brim of the glans corona, which can also be accompanied by foreskin ventral ...

journal_title：Frontiers in pediatrics

authors： Piñeyro-Ruiz C,Serrano H,Jorge I,Miranda-Valentin E,Pérez-Brayfield MR,Camafeita E,Mesa R,Vázquez J,Jorge JC

更新日期：2020-12-23 00:00:00

abstract：:Fetal sex is associated with striking differences during in utero development, fetal-to-neonatal transition, and postnatal morbidity and mortality. Male sex fetuses are apparently protected while in utero resulting in a higher secondary sex rate for males than for females. However, during fetal-to-neonatal transition ...

journal_title：Frontiers in pediatrics

authors： Lorente-Pozo S,Parra-Llorca A,Torres B,Torres-Cuevas I,Nuñez-Ramiro A,Cernada M,García-Robles A,Vento M

更新日期：2018-04-23 00:00:00

abstract：UNLABELLED:Even though in the corporate world psychological science has been widely used, the formal use of evidence-based psychology in important areas of clinical medicine has been scanty at best. It was the aim of this study to determine the efficacy of a psychologist-led 2-week nurse educator training on the infect...

journal_title：Frontiers in pediatrics

authors： Van Rostenberghe H,Short J,Ramli N,Geok TB,Subramaniam S,Che Yaakob CA,Othman A,Ibrahim NR,Ho J,Mohamed Z,Hasan H

更新日期：2014-11-19 00:00:00

abstract：Aim:The purpose of this study is to describe the development of an external 3-dimensional (3D) scanner as a noninvasive method for imaging chest wall deformities. It allows objective assessment, reconstruction of the area of interest, and evaluation of the severity of the deformity by using external indexes. External ...

journal_title：Frontiers in pediatrics

authors： Lain A,Garcia L,Gine C,Tiffet O,Lopez M

更新日期：2017-12-04 00:00:00

abstract：:This mini review provides an overview of the issues and challenges inherent in autosomal recessive polycystic kidney disease (ARPKD), with a particular focus on the neurological factors and neurocognitive functioning of this population. ARPKD typically is discovered at the end of pregnancy or during the neonatal devel...

journal_title：Frontiers in pediatrics

authors： Hooper SR

更新日期：2017-05-15 00:00:00

abstract：:Background: Survival of very-low-birth-weight infants is improving in neonatology and family-centered-care might contribute to premature infants' clinical outcomes. Aim: To evaluate a family-centered care intervention on clinical outcomes of very-low-birth-weight infants. Methods: A quasi-experimental study was conduc...

journal_title：Frontiers in pediatrics

authors： Lv B,Gao XR,Sun J,Li TT,Liu ZY,Zhu LH,Latour JM

更新日期：2019-04-12 00:00:00

abstract：BACKGROUND:Phenylketonuria (PKU) is caused by the inherited defect of the phenylalanine hydroxylase enzyme, which converts phenylalanine (Phe) into tyrosine (Tyr). Neonatal screening programs and early treatment have radically changed the natural history of PKU. Nevertheless, an increased risk of neurocognitive and psy...

journal_title：Frontiers in pediatrics

authors： Leuzzi V,Mannarelli D,Manti F,Pauletti C,Locuratolo N,Carducci C,Carducci C,Vanacore N,Fattapposta F

更新日期：2014-06-23 00:00:00

abstract：:Background: Necrotizing enterocolitis (NEC) is the most common life-threatening gastrointestinal condition among very and extremely preterm infants. Stem cell therapy has shown some promising protective effects in animal models of intestinal injury, including NEC, but no systematic review has yet evaluated the preclin...

journal_title：Frontiers in pediatrics

authors： Villamor-Martinez E,Hundscheid T,Kramer BW,Hooijmans CR,Villamor E

更新日期：2020-12-09 00:00:00