Relevant Outcomes in Pediatric Acute Respiratory Distress Syndrome Studies.

abstract：:Background: Viral respiratory tract infections (VRTI) may cause severe respiratory and sepsis-like symptoms in infants hospitalized in the neonatal intensive care unit (NICU). Little is known about the frequencies of VRTI in relation to visiting policies in the NICU. Objective: Aim of this study was to evaluate the fr...

journal_title：Frontiers in pediatrics

authors： Kidszun A,Neurohr A,Gröndahl B,Tippmann S,Schreiner D,Winter J,Mahmoudpour SH,Gehring S,Mildenberger E

更新日期：2020-11-16 00:00:00

abstract：:Objective: To examine the understanding of the concept peak oxygen uptake (peak VO2) among children and adolescents at different ages from a developmental perspective. Methods: A total of 549 children and adolescents aged 8 to 16 were recruited and instructed to fill in a 20-item Peak VO2Understanding Inventory develo...

journal_title：Frontiers in pediatrics

authors： Wong SWL,Yu CCW,Li AM

更新日期：2021-01-14 00:00:00

abstract：:Lung function is an important tool in the diagnosis and monitoring of patients with asthma at all ages. Airway obstruction is a typical feature of asthma and it can be assessed with several lung function techniques. Spirometry, respiratory resistance and reactance, and lung volumes are available to measure it at diffe...

journal_title：Frontiers in pediatrics

authors： Calogero C,Fenu G,Lombardi E

更新日期：2018-06-26 00:00:00

abstract：:Background: Although WU polyomavirus (WU) and KI polyomavirus (KI) have been demonstrated to infect the human respiratory tract, it remains unclear if WU or KI cause human disease. We sought to further investigate the relationship between WU and KI infection and respiratory disease in a pediatric population with respi...

journal_title：Frontiers in pediatrics

authors： Hansen-Estruch C,Coleman KK,Thoon KC,Low JG,Anderson BD,Gray GC

更新日期：2018-08-17 00:00:00

abstract：:Asthma is the most common chronic disease in children. As suggested by international guidelines, the main goals of asthma treatment are symptoms control and lung function preservation, through a stepwise and control-based approach. The first line therapy based on inhaled corticosteroids may fail to reach control in mo...

journal_title：Frontiers in pediatrics

authors： Maglione M,Poeta M,Santamaria F

更新日期：2019-01-16 00:00:00

abstract：:During early post-natal life, neonates must adjust to the transition from the sheltered intra-uterine environment to the microbe-laden external world, wherein they encounter a constellation of antigens and the colonization by the microbiome. At this vulnerable stage, neonatal immune responses are considered immature a...

journal_title：Frontiers in pediatrics

authors： Tsafaras GP,Ntontsi P,Xanthou G

更新日期：2020-01-28 00:00:00

abstract：:Objectives: Severe congenital neutropenia (SCN) is a primary immunodeficiency disease characterized by the early onset of recurrent infections and persistent severe neutropenia, with or without genetic defect. We aimed to study the different clinical features and hematological and bone marrow characteristics of patien...

journal_title：Frontiers in pediatrics

authors： Gong RL,Wu J,Chen TX

更新日期：2018-10-16 00:00:00

abstract：:Response to early intervention programs in autism is variable. However, the factors associated with positive versus poor treatment outcomes remain unknown. Hence the issue of which intervention/s should be chosen for an individual child remains a common dilemma. We argue that lack of knowledge on "what works for whom ...

journal_title：Frontiers in pediatrics

authors： Vivanti G,Prior M,Williams K,Dissanayake C

更新日期：2014-06-20 00:00:00

abstract：:Animal models provide convenient and clinically relevant tools in the research on neurodegenerative diseases. Studies on developmental disorders extensively rely on the use of laboratory rodents. The present mini-review proposes an alternative translational model based on the use of fetal bovine brain tissue. The bovi...

journal_title：Frontiers in pediatrics

authors： Peruffo A,Cozzi B

更新日期：2014-07-10 00:00:00

abstract：:Objective: In many patients with congenital heart disease (CHD) arterial blood flow to the arms is inhibited due to shunt surgery in infancy. This study investigates the handgrip strength of patients with CHD in regard to previous shunt procedures. Patients and Methods: Handgrip was evaluated in 424 patients with vari...

journal_title：Frontiers in pediatrics

authors： Müller J,Röttgers L,Neidenbach RC,Oberhoffer R,Ewert P,Hager A

更新日期：2018-09-06 00:00:00

abstract：:Objectives: In 2014 probiotic supplementation (Lactobacillus acidophilus and Bifidobacterium longum subspecies infantis; InfloranⓇ) was introduced as standard of care to prevent necrotizing enterocolitis (NEC) in extremely preterm infants in Norway. We aimed to evaluate the influence of probiotics and antibiotic thera...

journal_title：Frontiers in pediatrics

authors： Esaiassen E,Hjerde E,Cavanagh JP,Pedersen T,Andresen JH,Rettedal SI,Støen R,Nakstad B,Willassen NP,Klingenberg C

更新日期：2018-11-16 00:00:00

abstract：:Sarcoidosis (SD) is a systemic granulomatous condition that is especially encountered in young adults and rarely in children, affecting predominantly the lungs and lymph nodes. We report the case of a 14-year-old teenage boy admitted to our clinic for nausea, vomiting, and weight loss. Clinical examination at the time...

journal_title：Frontiers in pediatrics

authors： Mărginean CO,Meliţ LE,Grigorescu G,Puiac C,Simu I

更新日期：2020-08-26 00:00:00

abstract：:Severe invasive infections such as brain abscess in a child should prompt an immune evaluation. Specific granule deficiency (SGD) is a rare morphologic neutrophil granular defect characterized by reduced granules within neutrophils, absence of granule proteins, and bilobed nuclei. Patients are susceptible to invasive ...

journal_title：Frontiers in pediatrics

authors： Leszcynska M,Patel B,Morrow M,Chamizo W,Tuite G,Berman DM,Potthast K,Hsu AP,Holland SM,Leiding JW

更新日期：2020-04-22 00:00:00

abstract：OBJECTIVE:We investigated the relationship between influenza seasonality and outcome of very low birth weight infants (VLBWI) in a large observational cohort study of the German Neonatal Network. MATERIALS AND METHODS:Within the observational period (July 2009 until December 2014), five influenza seasons occurred (mea...

journal_title：Frontiers in pediatrics

authors： Härtel C,Humberg A,Viemann D,Stein A,Orlikowsky T,Rupp J,Kopp MV,Herting E,Göpel W

更新日期：2016-11-30 00:00:00

abstract：:Acute myeloid leukemia (AML) is the second most common leukemia of childhood and is associated with high rates of chemotherapy resistance and relapse. Clinical outcomes for children with AML treated with maximally intensive multi-agent chemotherapy lag far behind those of children with the more common acute lymphoblas...

journal_title：Frontiers in pediatrics

authors： Sexauer AN,Tasian SK

更新日期：2017-11-20 00:00:00

abstract：:Introduction: Surfactant proteins (SP) have been shown to be inherent proteins of the human CNS and are altered during acute and chronic disturbances of CSF circulation. Aim of the study was to examine the changes of surfactant protein concentrations in CSF of preterm babies suffering from intraventricular hemorrhage....

journal_title：Frontiers in pediatrics

authors： Krause M,Härtig W,Mahr CV,Richter C,Schob J,Puchta J,Hoffmann KT,Nestler U,Thome U,Knüpfer M,Gebauer C,Schob S

更新日期：2020-09-25 00:00:00

abstract：:A 3-year-old girl was admitted to our hospital for the correction of atrial septal defect (ASD). Open heart operation with cardiopulmonary bypass is dangerous because the patient also had hereditary spherocytosis, which put her at risk for hemolytic anemia. Therefore, percutaneous transcatheter closure for ASD was cho...

journal_title：Frontiers in pediatrics

authors： Ji Z,Liu N,Du Z,Luo G,Bing Z,Xing Q,Pan S

更新日期：2019-12-17 00:00:00

abstract：:Since the advent of extracorporeal membrane oxygenation (ECMO) over 40 years ago, there has been increasing interest in the use of the extracorporeal circuit as a platform for providing multiple organ support. In this review, we will examine the evidence for the use of continuous renal replacement therapy, therapeutic...

journal_title：Frontiers in pediatrics

authors： Canter MO,Daniels J,Bridges BC

更新日期：2018-04-03 00:00:00

abstract：:Systemic inflammation and duration of immobilization are strong independent risk factors for the development of intensive care unit-acquired weakness (ICUAW). Activation of the pro-inflammatory transcription factor nuclear factor-κB (NF-κB) results in muscle wasting during disuse-induced skeletal muscle atrophy (ICU b...

journal_title：Frontiers in pediatrics

authors： Meduri GU,Schwingshackl A,Hermans G

更新日期：2016-08-02 00:00:00

abstract：:Childhood asthma is actually defined as a heterogeneous disease, including different clinical variants and partially sharing similar immune mechanisms. Asthma management is mainly focused on maintaining the control of the disease and reducing the risk of adverse outcomes. Most children achieve good control with standa...

journal_title：Frontiers in pediatrics

authors： Licari A,Manti S,Castagnoli R,Marseglia A,Foiadelli T,Brambilla I,Marseglia GL

更新日期：2019-07-12 00:00:00

abstract：:In genome science, the advancement in high-throughput sequencing technologies and bioinformatics analysis is facilitating the better understanding of Mendelian and complex trait inheritance. Charting the genetic basis of complex diseases - including pediatric cancer, and interpreting huge amount of next-generation seq...

journal_title：Frontiers in pediatrics

authors： Manwar Hussain MR,Khan A,Ali Mohamoud HS

更新日期：2014-03-03 00:00:00

abstract：:Introduction: Primary repair of esophageal atresia (EA) in infants with very low birth weight (VLBW) and extremely low birth weight (ELBW) has been widely performed in pediatric surgery. However, several studies have shown that complication rates in infants with VLBW are high. We hypothesize preterm children benefit f...

journal_title：Frontiers in pediatrics

authors： Ritz LA,Widenmann-Grolig A,Jechalke S,Bergmann S,von Schweinitz D,Lurz E,Hubertus J

更新日期：2020-11-17 00:00:00

abstract：:Background: Survival of very-low-birth-weight infants is improving in neonatology and family-centered-care might contribute to premature infants' clinical outcomes. Aim: To evaluate a family-centered care intervention on clinical outcomes of very-low-birth-weight infants. Methods: A quasi-experimental study was conduc...

journal_title：Frontiers in pediatrics

authors： Lv B,Gao XR,Sun J,Li TT,Liu ZY,Zhu LH,Latour JM

更新日期：2019-04-12 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a chronic, immune-mediated, non-curable disease. The incidence of IBD appears to have risen over the last few decades especially in the pediatric age group. IBD usually presents with gastrointestinal symptoms, including abdominal pain, diarrhea, and bleeding per rectum but can also ...

journal_title：Frontiers in pediatrics

authors： El-Matary W,Bernstein CN

更新日期：2020-07-17 00:00:00

abstract：:The glomerular basement membrane (GBM) is a specialized structure with a significant role in maintaining the glomerular filtration barrier. This GBM is formed from the fusion of two basement membranes during development and its function in the filtration barrier is achieved by key extracellular matrix components inclu...

journal_title：Frontiers in pediatrics

authors： Chew C,Lennon R

更新日期：2018-01-29 00:00:00

abstract：:While awareness and understanding of concussion have improved drastically, post-concussion management in academic settings is still at its infancy. The aim of the study was to examine to what extent concussion influences academic performance and to whether there would be a difference in concussion effects on academic ...

journal_title：Frontiers in pediatrics

authors： Holmes A,Chen Z,Yahng L,Fletcher D,Kawata K

更新日期：2020-03-04 00:00:00

abstract：:Introduction: Hospital response to the COVID-19 outbreak has involved the cancellation of elective, deferrable surgeries throughout Europe in order to ensure capacity for emergent surgery and a selection of elective but non-deferrable surgeries. The purpose of this document is to propose technical strategies to assist...

journal_title：Frontiers in pediatrics

authors： Pini Prato A,Conforti A,Almstrom M,Van Gemert W,Scuderi MG,Khen-Dunlop N,Draghici I,Mendoza-Sagaon M,Giné Prades C,Chiarenza F,Steyaert H

更新日期：2020-05-07 00:00:00

abstract：:A subset of patients with Ataxia-Telangiectasia (A-T) have dramatically reduced levels of IgG, IgA, and IgE with retained or elevated IgM levels. Several reports suggest that these A-T patients with a "hyper-IgM phenotype" (HIgM) suffer more clinical immunologic consequences than other A-T patients. The immunopatholog...

journal_title：Frontiers in pediatrics

authors： Meyer AK,Banks M,Nadasdy T,Clark JJ,Zheng R,Gelfand EW,Abbott JK

更新日期：2019-10-24 00:00:00

abstract：:Objective: Magnetic resonance imaging (MRI) and cardiac catheterization are diagnostic tools for right ventricle dysfunction (RVD), but those are expensive and often unavailable techniques. Thus, our objective was to identify clinical and/or echocardiographic variables capable of predicting a catheterization-based dia...

journal_title：Frontiers in pediatrics

authors： Márquez-González H,Vargas MH,Yáñez-Gutiérrez L,Almeida-Gutiérrez E,Garduño-Espinosa J

更新日期：2018-06-26 00:00:00

abstract：:Background: Cystinuria is an inborn error of metabolism that manifests with renal stones due to defective renal epithelial cell transport of cystine which resulted from pathogenic variants in the SLC3A1 and/or SLC7A9 genes. Among nephrolithiasis diseases, cystinuria is potentially treatable, and further stone formatio...

journal_title：Frontiers in pediatrics

authors： Alghamdi M,Alhasan KA,Taha Elawad A,Salim S,Abdelhakim M,Nashabat M,Raina R,Kari J,Alfadhel M

更新日期：2020-11-11 00:00:00