Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants.

abstract：:Although antibiotics confer significant health benefits in treating or preventing bacterial infections, an accumulating wealth of evidence illustrates their detrimental effect on host-microbiota homeostasis, posing a serious menace to the global public health. In recent years, it is becoming evident that infants, who ...

journal_title：Frontiers in pediatrics

authors： Shekhar S,Petersen FC

更新日期：2020-10-15 00:00:00

abstract：:Background: Early and non-invasive diagnosis of common diseases is of great importance in the care of preterm infants. We hypothesized that volatile organic compounds (VOC) can be successfully measured in the neonatal incubator atmosphere. Methods: This is a feasibility study to investigate whether the discrimination ...

journal_title：Frontiers in pediatrics

authors： Steinbach J,Goedicke-Fritz S,Tutdibi E,Stutz R,Kaiser E,Meyer S,Baumbach JI,Zemlin M

更新日期：2019-06-18 00:00:00

abstract：BACKGROUND:Acute gastroenteritis (AGE) causing dehydration with or without dysnatremias is a common childhood health challenge. While it is accepted that oral rehydration therapy is preferred, clinical factors or parent and healthcare provider preferences may lead to intravenous rehydration (IVR). Isotonic solutions ar...

journal_title：Frontiers in pediatrics

authors： Grisaru S,Xie J,Samuel S,Freedman SB

更新日期：2017-10-06 00:00:00

abstract：:Objective: To investigate the relationship of overnutrition (obese and overweight) with severity of illness in children hospitalized with acute lower respiratory infections (ALRIs), frequency of viral coinfections and leptin levels. Methods: We studied 124 children <2 years old that were hospitalized for ALRI. Nutriti...

journal_title：Frontiers in pediatrics

authors： Arias-Bravo G,Valderrama G,Inostroza J,Reyes-Farías M,Garcia-Diaz DF,Zorondo-Rodríguez F,Fuenzalida LF

更新日期：2020-02-18 00:00:00

abstract：:High-pressure processing (HPP) is a non-thermal technology that is being increasingly applied in food industries worldwide. It was proposed that this method could be used as an alternative to holder pasteurization (HoP; 62.5°C, 30 min) in milk banks but its impact on the immunologic, enzymatic and hormonal components ...

journal_title：Frontiers in pediatrics

authors： Wesolowska A,Sinkiewicz-Darol E,Barbarska O,Strom K,Rutkowska M,Karzel K,Rosiak E,Oledzka G,Orczyk-Pawiłowicz M,Rzoska S,Borszewska-Kornacka MK

更新日期：2018-11-16 00:00:00

abstract：:Chronic granulomatous disease (CGD) is an inherited, genetically heterogeneous disease characterized by defective phagocytic cell microbicidal function, leading to increased susceptibility to bacterial and fungal infections. CGD is caused by mutations in components of the nicotinamide adenine dinucleotide phosphate (N...

journal_title：Frontiers in pediatrics

authors： de Albuquerque JAT,Lima AM,de Oliveira Junior EB,Ishizuka EK,Aragão-Filho WC,Bengala Zurro N,Mayumi Chiba S,Fernandes FR,Condino-Neto A

更新日期：2019-09-27 00:00:00

abstract：:Sarcoidosis (SD) is a systemic granulomatous condition that is especially encountered in young adults and rarely in children, affecting predominantly the lungs and lymph nodes. We report the case of a 14-year-old teenage boy admitted to our clinic for nausea, vomiting, and weight loss. Clinical examination at the time...

journal_title：Frontiers in pediatrics

authors： Mărginean CO,Meliţ LE,Grigorescu G,Puiac C,Simu I

更新日期：2020-08-26 00:00:00

abstract：:Background: The occurrence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated coronavirus disease 2019 (COVID-19) have profoundly affected adult kidney disease patients. In contrast, pediatric solid organ transplant recipients, including pediatric kidney transplant (KT) recipients, ...

journal_title：Frontiers in pediatrics

authors： Nailescu C,Khalid M,Wilson AC,Amanat F,Arregui S,Canas J,Hooks J,Krammer F,Schwaderer AL,Hains DS

更新日期：2020-10-30 00:00:00

abstract：:A 3-year-old girl was admitted to our hospital for the correction of atrial septal defect (ASD). Open heart operation with cardiopulmonary bypass is dangerous because the patient also had hereditary spherocytosis, which put her at risk for hemolytic anemia. Therefore, percutaneous transcatheter closure for ASD was cho...

journal_title：Frontiers in pediatrics

authors： Ji Z,Liu N,Du Z,Luo G,Bing Z,Xing Q,Pan S

更新日期：2019-12-17 00:00:00

abstract：:Introduction: Mutations in the contactin-associated protein-like 2 (CNTNAP2) gene (MIM#604569) encoding for CASPR2, a cell adhesion protein of the neurexin family, are known to be associated with autism, intellectual disability, and other neuropsychiatric disorders. A set of intronic deletions of CNTNAP2 gene has also...

journal_title：Frontiers in pediatrics

authors： Falsaperla R,Pappalardo XG,Romano C,Marino SD,Corsello G,Ruggieri M,Parano E,Pavone P

更新日期：2020-09-11 00:00:00

abstract：:Sickle cell disease (SCD) is a severe autosomal recessively inherited disorder of the red blood cell characterized by erythrocyte deformation caused by the polymerization of the abnormal hemoglobin, which leads to erythrocyte deformation and triggers downstream pathological changes. These include abnormal rheology, va...

journal_title：Frontiers in pediatrics

authors： Krishnamurti L

更新日期：2021-01-05 00:00:00

abstract：:Puberty is a sensitive period of life characterized by the appearance of secondary sex characteristics which leads to a complete sexual maturation. It physiologically starts between the age of 8 and 13 years in girls and 9 and 14 years in boys. In the last two decades, several studies have showed that start of puberty...

journal_title：Frontiers in pediatrics

authors： Farello G,Altieri C,Cutini M,Pozzobon G,Verrotti A

更新日期：2019-05-08 00:00:00

abstract：:During early post-natal life, neonates must adjust to the transition from the sheltered intra-uterine environment to the microbe-laden external world, wherein they encounter a constellation of antigens and the colonization by the microbiome. At this vulnerable stage, neonatal immune responses are considered immature a...

journal_title：Frontiers in pediatrics

authors： Tsafaras GP,Ntontsi P,Xanthou G

更新日期：2020-01-28 00:00:00

abstract：:Severe accidental hypothermia has been demonstrated to affect ventricular systolic and diastolic functions, and rewarming might be responsible of cardiovascular collapse. Until now, there have been only a few reports on severe accidental hypothermia, none of which involved children. Herein, we describe here a rare cas...

journal_title：Frontiers in pediatrics

authors： Vicinanza A,De Laet C,Rooze S,Willems A,Beretta-Piccoli X,Vens D,Voglet C,Jacquemart C,Massin M,Biarent D

更新日期：2019-03-29 00:00:00

abstract：:Oxidative stress results from excessive reactive oxygen species formation and/or inadequate antioxidant defense. Premature and critically ill infants are especially susceptible due to an immature intrinsic antioxidant system that cannot fully compensate for a free radical load. Oxidative stress is also associated with...

journal_title：Frontiers in pediatrics

authors： Stefanov G,Briyal S,Pais G,Puppala B,Gulati A

更新日期：2020-06-02 00:00:00

abstract：:Objectives: Mutations in the neuroblastoma-amplified sequence (NBAS) gene were originally described in patients with skeletal dysplasia or isolated liver disease of variable severity. Subsequent publications reported a more complex phenotype. Among multisystemic clinical symptoms, we were particularly interested in th...

journal_title：Frontiers in pediatrics

authors： Khoreva A,Pomerantseva E,Belova N,Povolotskaya I,Konovalov F,Kaimonov V,Gavrina A,Zimin S,Pershin D,Davydova N,Burlakov V,Viktorova E,Roppelt A,Kalinina E,Novichkova G,Shcherbina A

更新日期：2020-09-15 00:00:00

abstract：INTRODUCTION:The usefulness of qualitative or quantitative volumetric magnetic resonance imaging (MRI) in early detection of brain structural changes and prediction of adverse outcomes in neonatal illnesses warrants further investigation. Our aim was to correlate certain brain injuries and the brain volume of feeding-r...

journal_title：Frontiers in pediatrics

authors： Kashou NH,Dar IA,El-Mahdy MA,Pluto C,Smith M,Gulati IK,Lo W,Jadcherla SR

更新日期：2017-04-10 00:00:00

abstract：:The first successful total right heart bypass via atriopulmonary anastomosis (APA) were reported in 1971 for patients with tricuspid atresia. At the Children's Hospital of Buenos Aires, the cohort of such procedures started in July, when the first fenestrated right heart by pass was performed, with the interposition o...

journal_title：Frontiers in pediatrics

authors： Kreutzer C,Kreutzer J,Kreutzer GO

更新日期：2013-12-18 00:00:00

abstract：:Data regarding the safety of using therapeutic hypothermia (TH) with extracorporeal membrane oxygenation (ECMO) in neonates with both hypoxic ischemic encephalopathy (HIE), and respiratory failure are lacking. TH is not associated with an increased incidence of hemostatic complications, but hypothermia may impair coag...

journal_title：Frontiers in pediatrics

authors： Okulu E,Erdeve O,Pekcici BB,Kendirli T,Eyileten Z,Atasay B,Arsan S

更新日期：2019-03-22 00:00:00

abstract：:Introduction: Primary repair of esophageal atresia (EA) in infants with very low birth weight (VLBW) and extremely low birth weight (ELBW) has been widely performed in pediatric surgery. However, several studies have shown that complication rates in infants with VLBW are high. We hypothesize preterm children benefit f...

journal_title：Frontiers in pediatrics

authors： Ritz LA,Widenmann-Grolig A,Jechalke S,Bergmann S,von Schweinitz D,Lurz E,Hubertus J

更新日期：2020-11-17 00:00:00

abstract：:Background: This paper presents design and results from preliminary evaluation of Tangible Geometric Games (TAG-Games) for cognitive assessment in young children. The TAG-Games technology employs a set of sensor-integrated cube blocks, called SIG-Blocks, and graphical user interfaces for test administration and real-t...

journal_title：Frontiers in pediatrics

authors： Lee K,Jeong D,Schindler RC,Hlavaty LE,Gross SI,Short EJ

更新日期：2018-05-08 00:00:00

abstract：:Neonatal spinal cord injury is a rare complication of birth trauma by difficult delivery. The typical manifestations are often catastrophic, include decreased or absent movement, loss of reflexes, apnea or periodic breathing, and a lack of response to painful stimulation. The outcome is usually fatal or severe, with l...

journal_title：Frontiers in pediatrics

authors： Lee CC,Chou IJ,Chang YJ,Chiang MC

更新日期：2020-09-29 00:00:00

abstract：:Introduction: Carnitine-acylcarnitine translocase deficiency (CACTD) is a rare and life-threatening autosomal recessive disorder of mitochondrial fatty acid oxidation caused by variation of the Solute carrier family 25 member 20 (SLC25A20) gene. Carnitine-acylcarnitine translocase is one of the crucial transport prote...

journal_title：Frontiers in pediatrics

authors： Chen M,Cai Y,Li S,Xiong H,Liu M,Ma F,Xiao X,Hao H

更新日期：2020-10-30 00:00:00

abstract：:Background: Survival of very-low-birth-weight infants is improving in neonatology and family-centered-care might contribute to premature infants' clinical outcomes. Aim: To evaluate a family-centered care intervention on clinical outcomes of very-low-birth-weight infants. Methods: A quasi-experimental study was conduc...

journal_title：Frontiers in pediatrics

authors： Lv B,Gao XR,Sun J,Li TT,Liu ZY,Zhu LH,Latour JM

更新日期：2019-04-12 00:00:00

abstract：OBJECTIVES:Nationally accredited simulation courses such as advance pediatric life support and pediatric advance life support are recommended for health care professionals (HCPs) at two yearly intervals as a minimum requirement, despite literature evidence suggesting rapid decline in knowledge shortly after course comp...

journal_title：Frontiers in pediatrics

authors： Ojha R,Liu A,Champion BL,Hibbert E,Nanan RK

更新日期：2014-11-24 00:00:00

abstract：:Asthma is no longer considered a single disease, but a common label for a set of heterogeneous conditions with shared clinical symptoms but associated with different cellular and molecular mechanisms. Several wheezing phenotypes coexist at preschool age but not all preschoolers with recurrent wheezing develop asthma a...

journal_title：Frontiers in pediatrics

authors： Castro-Rodriguez JA,Cifuentes L,Martinez FD

更新日期：2019-07-31 00:00:00

abstract：:Background: Abernethy malformation is a rare vascular anomaly of the portal venous system, which is also known as congenital portosystemic shunts (CPSS). The clinical manifestations of this anomaly can be serious, including hepatopulmonary syndrome(HPS), which can lead to significant hypoxemia and cyanosis. Case Prese...

journal_title：Frontiers in pediatrics

authors： Lin Y,Li X,Li S,Ba H,Wang H,Zhu L

更新日期：2020-10-27 00:00:00

abstract：:Urolithiasis can affect all children even preschool ones. Diagnostic difficulties in the youngest children are due to the problems in locating pain and determining its character and severity. In keeping with the ALARA (As Low As Reasonably Achievable) protocol, the number of imaging tests possible to perform is very l...

journal_title：Frontiers in pediatrics

authors： Halinski A,Halinski A,Zaniew M,Kudliński B,Soltysiak J,Sobolewski B,Steyaert H

更新日期：2019-09-06 00:00:00

abstract：:Background: To evaluate the effects of pressure levels on cerebral hemodynamics in premature infants receiving nasal continuous positive airway pressure (nCPAP) during the first 3 days of life. Methods: Forty-four preterm infants treated with nCPAP were divided into two groups: very preterm infants [gestational age 1 ...

journal_title：Frontiers in pediatrics

authors： Zhou H,Hou X,Cheng R,Zhao Y,Qiu J

更新日期：2020-08-21 00:00:00

abstract：:Genetic polymorphisms in genes coding for inflammasome components nucleotide-binding oligomerization domain leucine rich repeat and pyrin domain-containing protein 3 (NLRP3) and caspase recruitment domain-containing protein 8 (CARD8) have been associated with autoinflammatory and autoimmune diseases. On the other hand...

journal_title：Frontiers in pediatrics

authors： Smigoc Schweiger D,Goricar K,Hovnik T,Mendez A,Bratina N,Brecelj J,Vidan-Jeras B,Battelino T,Dolzan V

更新日期：2019-03-12 00:00:00