Basement Membrane Defects in Genetic Kidney Diseases.

abstract：OBJECTIVES/HYPOTHESIS:Congenital aural atresia is a rare condition affecting 1 in 10,000-20,000 children a year. Surgery is required to restore hearing to facilitate normal development. The objective of this study was to compare outcomes in hearing, complications, and quality of life of surgical reconstruction of the e...

journal_title：Frontiers in pediatrics

authors： Farnoosh S,Mitsinikos FT,Maceri D,Don DM

更新日期：2014-01-22 00:00:00

abstract：:Introduction: Childhood obesity is occurring at alarming rates in both developed and developing countries. "Obesogenic" environmental factors must be associated with variants of different risk alleles to determine polygenic or common obesity, and their impact depends on different developmental stages.The interaction b...

journal_title：Frontiers in pediatrics

authors： Mǎrginean CO,Mǎrginean C,Meliţ LE

更新日期：2018-10-04 00:00:00

abstract：:Objectives: Severe congenital neutropenia (SCN) is a primary immunodeficiency disease characterized by the early onset of recurrent infections and persistent severe neutropenia, with or without genetic defect. We aimed to study the different clinical features and hematological and bone marrow characteristics of patien...

journal_title：Frontiers in pediatrics

authors： Gong RL,Wu J,Chen TX

更新日期：2018-10-16 00:00:00

abstract：:Objectives: Mutations in the neuroblastoma-amplified sequence (NBAS) gene were originally described in patients with skeletal dysplasia or isolated liver disease of variable severity. Subsequent publications reported a more complex phenotype. Among multisystemic clinical symptoms, we were particularly interested in th...

journal_title：Frontiers in pediatrics

authors： Khoreva A,Pomerantseva E,Belova N,Povolotskaya I,Konovalov F,Kaimonov V,Gavrina A,Zimin S,Pershin D,Davydova N,Burlakov V,Viktorova E,Roppelt A,Kalinina E,Novichkova G,Shcherbina A

更新日期：2020-09-15 00:00:00

abstract：:We report on the results of a literature review regarding the indications and results of operations to increase bladder outlet resistance to achieve dryness in children with neurogenic sphincter incompetence (NSBD). The relative advantages and disadvantages of injection of bulking agents, periurethral slings, bladder ...

journal_title：Frontiers in pediatrics

authors： Ludwikowski BM,Bieda JC,Lingnau A,González R

更新日期：2019-03-26 00:00:00

abstract：:In genome science, the advancement in high-throughput sequencing technologies and bioinformatics analysis is facilitating the better understanding of Mendelian and complex trait inheritance. Charting the genetic basis of complex diseases - including pediatric cancer, and interpreting huge amount of next-generation seq...

journal_title：Frontiers in pediatrics

authors： Manwar Hussain MR,Khan A,Ali Mohamoud HS

更新日期：2014-03-03 00:00:00

abstract：:While awareness and understanding of concussion have improved drastically, post-concussion management in academic settings is still at its infancy. The aim of the study was to examine to what extent concussion influences academic performance and to whether there would be a difference in concussion effects on academic ...

journal_title：Frontiers in pediatrics

authors： Holmes A,Chen Z,Yahng L,Fletcher D,Kawata K

更新日期：2020-03-04 00:00:00

abstract：:The burden of severe hearing impairment is increasing with two-thirds of these hearing impaired people residing in developing countries. Newborn hearing screening helps to identify early, babies who need intervention in order to prevent future disability. Neither universal nor targeted hearing screening programme is a...

journal_title：Frontiers in pediatrics

authors： Labaeka AA,Tongo OO,Ogunbosi BO,Fasunla JA

更新日期：2018-07-16 00:00:00

abstract：:Objective: The effective diagnosis of Mycoplasma pneumoniae (MP) pneumonia (MPP) in children has been hampered by the difficulty of achieving an early diagnosis. The simultaneous amplification and testing (SAT) has the potential for early diagnosis of MP in children. Methods: Of the 1,180 children enrolled in this stu...

journal_title：Frontiers in pediatrics

authors： Li J,Sun L,Wu X,Guo Y,Jiao W,Xiao J,Xu B,Shen A

更新日期：2019-10-25 00:00:00

abstract：:Vascular tumors in pediatric patients are an important entity for the clinician to recognize and correctly diagnose. They may present at birth or develop at any point during infancy, childhood, or adolescence. Most are benign, but even benign lesions may have significant morbidity without proper intervention. Malignan...

journal_title：Frontiers in pediatrics

authors： Hinen HB,Trenor CC 3rd,Wine Lee L

更新日期：2020-10-22 00:00:00

abstract：:Chronic active Epstein-Barr virus (EBV) infection (CAEBV) is an EBV-associated lymphoproliferative disease characterized by repeated or sustainable infectious mononucleosis (IM)-like symptoms. EBV is usually detected in B cells in patients who have IM or Burkitt's lymphoma and even in patients with X-linked lymphoprol...

journal_title：Frontiers in pediatrics

authors： Tanita K,Hoshino A,Imadome KI,Kamiya T,Inoue K,Okano T,Yeh TW,Yanagimachi M,Shiraishi A,Ishimura M,Schober T,Rohlfs M,Takagi M,Imai K,Takada H,Ohga S,Klein C,Morio T,Kanegane H

更新日期：2019-02-04 00:00:00

abstract：:Deficiency of adenosine deaminase 2 (DADA2) is a monogenic form of systemic vasculopathy that often presents during early childhood. Linked to biallelic mutations in ADA2 (previously CECR1), DADA2 was initially described as a syndrome of recurrent fever, livedo racemosa, early-onset strokes, and peripheral vasculopath...

journal_title：Frontiers in pediatrics

authors： Lee PY

更新日期：2018-10-18 00:00:00

abstract：:The COVID-19 crisis has pressured hospital-based care for children with high-risk asthma as they have become deprived of regular clinical evaluations. However, COVID-19 also provided important lessons about implementing novel directions for care. Personalized eHealth technology, tailored to the individual and the heal...

journal_title：Frontiers in pediatrics

authors： van der Kamp MR,Tabak M,de Rooij SEJA,van Lierop PPE,Thio BJ

更新日期：2020-09-08 00:00:00

abstract：:Asthma is no longer considered a single disease, but a common label for a set of heterogeneous conditions with shared clinical symptoms but associated with different cellular and molecular mechanisms. Several wheezing phenotypes coexist at preschool age but not all preschoolers with recurrent wheezing develop asthma a...

journal_title：Frontiers in pediatrics

authors： Castro-Rodriguez JA,Cifuentes L,Martinez FD

更新日期：2019-07-31 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a chronic, immune-mediated, non-curable disease. The incidence of IBD appears to have risen over the last few decades especially in the pediatric age group. IBD usually presents with gastrointestinal symptoms, including abdominal pain, diarrhea, and bleeding per rectum but can also ...

journal_title：Frontiers in pediatrics

authors： El-Matary W,Bernstein CN

更新日期：2020-07-17 00:00:00

abstract：:Background: Early and non-invasive diagnosis of common diseases is of great importance in the care of preterm infants. We hypothesized that volatile organic compounds (VOC) can be successfully measured in the neonatal incubator atmosphere. Methods: This is a feasibility study to investigate whether the discrimination ...

journal_title：Frontiers in pediatrics

authors： Steinbach J,Goedicke-Fritz S,Tutdibi E,Stutz R,Kaiser E,Meyer S,Baumbach JI,Zemlin M

更新日期：2019-06-18 00:00:00

abstract：:Background: Febrile urinary tract infections (FUTIs) are common among children, and are associated with a bacteraemia between 4 and 7% of cases. No data is available concerning the management of children with a bacteraemic FUTI. Objectives: To compare the antibiotic treatment (parenteral and total duration) among chil...

journal_title：Frontiers in pediatrics

authors： Goeller C,Desmarest M,Garraffo A,Bonacorsi S,Gaschignard J

更新日期：2020-05-28 00:00:00

abstract：:Fetal sex is associated with striking differences during in utero development, fetal-to-neonatal transition, and postnatal morbidity and mortality. Male sex fetuses are apparently protected while in utero resulting in a higher secondary sex rate for males than for females. However, during fetal-to-neonatal transition ...

journal_title：Frontiers in pediatrics

authors： Lorente-Pozo S,Parra-Llorca A,Torres B,Torres-Cuevas I,Nuñez-Ramiro A,Cernada M,García-Robles A,Vento M

更新日期：2018-04-23 00:00:00

abstract：:High-pressure processing (HPP) is a non-thermal technology that is being increasingly applied in food industries worldwide. It was proposed that this method could be used as an alternative to holder pasteurization (HoP; 62.5°C, 30 min) in milk banks but its impact on the immunologic, enzymatic and hormonal components ...

journal_title：Frontiers in pediatrics

authors： Wesolowska A,Sinkiewicz-Darol E,Barbarska O,Strom K,Rutkowska M,Karzel K,Rosiak E,Oledzka G,Orczyk-Pawiłowicz M,Rzoska S,Borszewska-Kornacka MK

更新日期：2018-11-16 00:00:00

abstract：:Cystic kidney diseases comprise a varied collection of hereditary disorders, where renal cysts comprise a major element of their pleiotropic phenotype. In pediatric patients, the term polycystic kidney disease (PKD) commonly refers to two specific hereditary diseases, autosomal recessive polycystic kidney disease (ARP...

journal_title：Frontiers in pediatrics

authors： Sweeney WE Jr,Avner ED

更新日期：2017-04-19 00:00:00

abstract：:Childhood asthma is actually defined as a heterogeneous disease, including different clinical variants and partially sharing similar immune mechanisms. Asthma management is mainly focused on maintaining the control of the disease and reducing the risk of adverse outcomes. Most children achieve good control with standa...

journal_title：Frontiers in pediatrics

authors： Licari A,Manti S,Castagnoli R,Marseglia A,Foiadelli T,Brambilla I,Marseglia GL

更新日期：2019-07-12 00:00:00

abstract：:Recent studies have demonstrated that gut microbiota development is influenced by human biogeographic factors such as race, ethnicity, diet, lifestyle or culture-specific variations, and other environmental influences. However, biogeographic variation in gut microbiota assembly remains largely unexplored in Latin Amer...

journal_title：Frontiers in pediatrics

authors： Chew C,Barros KV,Weffort VRS,Maranhão HS,Laranjeira M,Knol J,Roeselers G,de Morais MB

更新日期：2020-12-07 00:00:00

abstract：:Background: Autosomal recessive primary microcephaly (Microcephaly Primary Hereditary, MCPH) is a rare disorder, affecting 1 in 10,000 children in areas where consanguineous marriages are common. WDR62 gene mutations are the second most common cause of MCPH. Herein, we report a case of primary microcephaly caused by t...

journal_title：Frontiers in pediatrics

authors： Yi YG,Lee DW,Kim J,Jang JH,Lee SM,Jang DH

更新日期：2019-11-07 00:00:00

abstract：:Objective: In many patients with congenital heart disease (CHD) arterial blood flow to the arms is inhibited due to shunt surgery in infancy. This study investigates the handgrip strength of patients with CHD in regard to previous shunt procedures. Patients and Methods: Handgrip was evaluated in 424 patients with vari...

journal_title：Frontiers in pediatrics

authors： Müller J,Röttgers L,Neidenbach RC,Oberhoffer R,Ewert P,Hager A

更新日期：2018-09-06 00:00:00

abstract：OBJECTIVE:This study aimed to evaluate circulating natriuretic peptides (NP) concentration in obese and non-obese children and adolescents with and without obstructive sleep apnea (OSA), and their levels following OSA treatment. METHODS:Subjects with habitual snoring and symptoms suggestive of OSA were recruited. They...

journal_title：Frontiers in pediatrics

authors： Li AM,Au CT,Zhu JY,Chan KC,Chan MH,Lee DL,Wing YK

更新日期：2014-03-24 00:00:00

abstract：:Introduction: The interest in laparoscopy in the treatment of ureteropelvic junction obstruction (UPJO) in children under 12 months of age remains controversial. The aim of this study is to evaluate feasibility and benefits of retroperitoneal laparoscopy (RL) compared to open surgery in this age group. Materials and M...

journal_title：Frontiers in pediatrics

authors： Kallas-Chemaly A,Peycelon M,Ali L,Grapin-Dagorno C,Carricaburu E,Philippe-Chomette P,Enezian G,Paye-Jaouen A,El-Ghoneimi A

更新日期：2019-05-24 00:00:00

abstract：:Background: Improved diagnostic tests are needed for the early identification of Mycobacterium tuberculosis-infected young children exposed to an active TB (aTB) index case. We aimed to compare the diagnostic accuracy of new blood-based tests to that of the tuberculin skin test (TST) for the identification of all infe...

journal_title：Frontiers in pediatrics

authors： Dreesman A,Dirix V,Smits K,Corbière V,Van Praet A,Debulpaep S,De Schutter I,Felderhof MK,Malfroot A,Singh M,Locht C,Mouchet F,Mascart F

更新日期：2019-07-25 00:00:00

abstract：:X-linked lymphoproliferative disease (XLP) is one of the X-linked primary immunodeficiency diseases (PIDs) with defective immune response to Epstein-Barr virus (EBV) infection. Chronic active EBV infection (CAEBV) and EBV-hemophagocytic lymphohistiocytosis (HLH) are recognized as systemic EBV-positive T-cell and natur...

journal_title：Frontiers in pediatrics

authors： Ishimura M,Eguchi K,Shiraishi A,Sonoda M,Azuma Y,Yamamoto H,Imadome KI,Ohga S

更新日期：2019-05-21 00:00:00

abstract：:Background: Childhood refractory mycoplasma pneumoniae (MP) pneumonia (RMPP) is a lung disease with elevated level of C-reactive protein and severe clinical and radiological deterioration. Whether bacterial co-infection contributes to disease of RMPP and whether inclusion of non-anti-MP antibiotics in treatment regime...

journal_title：Frontiers in pediatrics

authors： Liu JR,Lu J,Dong F,Li HM,Liu H,Tang XL,Guo YL,Zhao SY

更新日期：2018-10-26 00:00:00

abstract：UNLABELLED:Pediatric acute encephalopathy (AE) was sometimes attributed to virus infection. However, viral infection does not always result in AE. The risk factors for developing infantile AE upon virus infection remain to be determined. Here, we report an infant with AE co-infected with human herpesvirus-6 (HHV-6) and...

journal_title：Frontiers in pediatrics

authors： Nakata K,Kashiwagi M,Masuda M,Shigehara S,Oba C,Murata S,Kase T,Komano JA

更新日期：2015-04-02 00:00:00