Prevalence of Hearing Impairment Among High-Risk Newborns in Ibadan, Nigeria.

abstract：BACKGROUND:Although histologic chorioamnionitis (HCA) is known to be associated with poor outcomes in preterm infants, its clinical significance among term infants is not clearly known. OBJECTIVES:To investigate the utility of HCA in determining early onset clinical sepsis (EOCS) among term newborns. METHODS:The inci...

journal_title：Frontiers in pediatrics

authors： Cuna A,Hakima L,Tseng YA,Fornier B,Islam S,Quintos-Alagheband ML,Khullar P,Weinberger B,Hanna N

更新日期：2014-04-04 00:00:00

abstract：:Ataxia-telangiectasia (A-T) is an autosomal recessive disorder characterized by neurodegeneration, combined immunodeficiency, and oculocutaneous telangiectasia. The hyper-IgM phenotype of A-T, correlating with a class-switch recombination defect, IgG and IgA deficiency, T helper and B cell lymphopenia, immune dysregul...

journal_title：Frontiers in pediatrics

authors： Szczawińska-Popłonyk A,Ossowska L,Jończyk-Potoczna K

更新日期：2020-11-19 00:00:00

abstract：:Animal models provide convenient and clinically relevant tools in the research on neurodegenerative diseases. Studies on developmental disorders extensively rely on the use of laboratory rodents. The present mini-review proposes an alternative translational model based on the use of fetal bovine brain tissue. The bovi...

journal_title：Frontiers in pediatrics

authors： Peruffo A,Cozzi B

更新日期：2014-07-10 00:00:00

abstract：:Data regarding the safety of using therapeutic hypothermia (TH) with extracorporeal membrane oxygenation (ECMO) in neonates with both hypoxic ischemic encephalopathy (HIE), and respiratory failure are lacking. TH is not associated with an increased incidence of hemostatic complications, but hypothermia may impair coag...

journal_title：Frontiers in pediatrics

authors： Okulu E,Erdeve O,Pekcici BB,Kendirli T,Eyileten Z,Atasay B,Arsan S

更新日期：2019-03-22 00:00:00

abstract：:Background and Objective: Mild hypospadias is a birth congenital condition characterized by the relocation of the male urethral meatus from its typical anatomical position near the tip of the glans penis, to a lower ventral position up to the brim of the glans corona, which can also be accompanied by foreskin ventral ...

journal_title：Frontiers in pediatrics

authors： Piñeyro-Ruiz C,Serrano H,Jorge I,Miranda-Valentin E,Pérez-Brayfield MR,Camafeita E,Mesa R,Vázquez J,Jorge JC

更新日期：2020-12-23 00:00:00

abstract：:We describe a giant gastric phytobezoar in a child with repaired congenital esophageal atresia. At age two, a gastric interposition (pull-up) procedure was performed for severe and recurrent esophageal strictures. For 12 months post-gastric interposition, he experienced frequent respiratory illnesses requiring hospita...

journal_title：Frontiers in pediatrics

authors： Chacko A,Masters BI,Isles A

更新日期：2017-06-19 00:00:00

abstract：:Neonatal encephalopathy (NE) is associated with high mortality and morbidity. Factors predisposing to NE can be antenatal, perinatal, or a combination of both. Antenatal maternal factors, familial factors, genetic predisposition, hypoxic ischemic encephalopathy, infections, placental abnormalities, thrombophilia, coag...

journal_title：Frontiers in pediatrics

authors： Aslam S,Strickland T,Molloy EJ

更新日期：2019-04-16 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fped.2018.00316.]. ...

journal_title：Frontiers in pediatrics

authors： Ebrahimi-Fakhari D,Dillmann U,Flotats-Bastardas M,Poryo M,Abdul-Khaliq H,Shamdeen MG,Mischo B,Zemlin M,Meyer S

更新日期：2019-07-25 00:00:00

abstract：:Background: Optimal timing for resection of asymptomatic congenital lung malformations (CLMs) remains controversial. The aim of this study is to define optimal timing for surgical intervention of patients with CLMs and define clinical variables that affect surgical outcomes. Methods: An IRB-approved retrospective anal...

journal_title：Frontiers in pediatrics

authors： Duron V,Zenilman A,Griggs C,DeFazio J,Price JC,Fan W,Vivero M,Castrillon J,Schmaedick M,Iqbal E,Rothenberg S

更新日期：2020-02-14 00:00:00

abstract：:To date, the only known effective treatment for celiac disease (CD) is a strict gluten-free diet (GFD) for life. Patients with CD often find it difficult to adhere to strict GFD. Oats, compared with wheat, barley, and rye, contain less amounts of prolamins. Inclusion of oats in a GFD might be valuable due to their nut...

journal_title：Frontiers in pediatrics

authors： Spector Cohen I,Day AS,Shaoul R

更新日期：2019-09-26 00:00:00

abstract：:Background: This paper presents design and results from preliminary evaluation of Tangible Geometric Games (TAG-Games) for cognitive assessment in young children. The TAG-Games technology employs a set of sensor-integrated cube blocks, called SIG-Blocks, and graphical user interfaces for test administration and real-t...

journal_title：Frontiers in pediatrics

authors： Lee K,Jeong D,Schindler RC,Hlavaty LE,Gross SI,Short EJ

更新日期：2018-05-08 00:00:00

abstract：:Background: Pulmonary artery banding (PAB) is reported as an innovative strategy for children with end-stage heart failure (ESHF) to bridge to transplantation or recovery. We report our early experience with PAB to evaluate outcomes, indications, and limitations. Materials and Methods: This is a single-center prospect...

journal_title：Frontiers in pediatrics

authors： Di Candia A,Castaldi B,Bordin G,Cerutti A,Reffo E,Biffanti R,Di Salvo G,Vida VL,Padalino MA

更新日期：2020-07-16 00:00:00

abstract：:Thrombocytopenia and pancytopenia, occurring in patients with Fanconi anemia (FA), are interpreted either as progression to bone marrow failure or as developing myelodysplasia. On the other hand, immune thrombocytopenia (ITP) represents an acquired and often self-limiting benign hematologic disorder, associated with p...

journal_title：Frontiers in pediatrics

authors： Karastaneva A,Lanz S,Wawer A,Behrends U,Schindler D,Dietrich R,Burdach S,Urban C,Benesch M,Seidel MG

更新日期：2015-06-08 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disorder of the gastrointestinal tract associated with significant morbidity. While IBD occurs in genetically susceptible individuals, the etiology is multifactorial, involving environmental influences, intestinal dysbiosis, and altered immune respon...

journal_title：Frontiers in pediatrics

authors： Foster A,Jacobson K

更新日期：2013-11-06 00:00:00

abstract：OBJECTIVES:To determine the influence of family, peers, school, and physicians on exercise in pediatric oncology patients and evaluate the barriers to physical activity (PA) levels in this population. METHODS:A search of PubMed and Google Scholar resulted in 12 related articles. The articles were assessed for the infl...

journal_title：Frontiers in pediatrics

authors： Yelton L,Forbis S

更新日期：2016-12-19 00:00:00

abstract：:Background: Clinical practice guidelines recommended that hypertension in children and adolescents should be defined based on elevated blood pressure (BP) on at least three separate occasions. Therefore, in the present study, we aimed to estimate the prevalence of hypertension based on three separate visits among Chin...

journal_title：Frontiers in pediatrics

authors： Zhang Q,Yang L,Zhang Y,Zhao M,Liang Y,Xi B

更新日期：2019-07-24 00:00:00

abstract：:Objective: Intravenous immunoglobulin (IVIG) therapy is a useful first-line treatment for Kawasaki disease (KD); however, 10-20% of patients fail to respond and require additional IVIG. Soluble CD163 (sCD163) is considered a biomarker for macrophage activation. There are no reports measuring serum sCD163 in KD patient...

journal_title：Frontiers in pediatrics

authors： Azuma Y,Suzuki Y,Okada S,Matsuguma C,Wakiguchi H,Ohnishi Y,Furuta T,Miyake A,Yasudo H,Ichihara K,Ohga S,Hasegawa S

更新日期：2020-04-07 00:00:00

abstract：:Introduction: Hospital response to the COVID-19 outbreak has involved the cancellation of elective, deferrable surgeries throughout Europe in order to ensure capacity for emergent surgery and a selection of elective but non-deferrable surgeries. The purpose of this document is to propose technical strategies to assist...

journal_title：Frontiers in pediatrics

authors： Pini Prato A,Conforti A,Almstrom M,Van Gemert W,Scuderi MG,Khen-Dunlop N,Draghici I,Mendoza-Sagaon M,Giné Prades C,Chiarenza F,Steyaert H

更新日期：2020-05-07 00:00:00

abstract：:Introduction: Decreased respiratory muscle strength in patients with cystic fibrosis (CF) may cause progressive exercise intolerance during cardiopulmonary exercise testing (CPET), and may contribute to the development of chronic respiratory insufficiency. The aim of this study is to evaluate exercise tolerance during...

journal_title：Frontiers in pediatrics

authors： Sovtic A,Minic P,Markovic-Sovtic G,Trajkovic GZ

更新日期：2018-09-04 00:00:00

abstract：:In recent years, there have been major advances in the application of non-invasive techniques to predict pregnancy-related complications, for example by measuring cell-free RNA (cfRNA) in maternal blood. In contrast to cell-free DNA (cfDNA), which is already in clinical use to diagnose fetal aneuploidy, circulating RN...

journal_title：Frontiers in pediatrics

authors： Moufarrej MN,Wong RJ,Shaw GM,Stevenson DK,Quake SR

更新日期：2020-12-14 00:00:00

abstract：:Objective: 11β-hydroxylase deficiency (11βOHD) is a rare autosomal recessive disorder caused by mutations in the CYP11B1 gene. It is characterized by virilization, hypertension, and significant final height impairment. In this study, we aim to investigate the clinical and molecular characteristics of four unrelated Ch...

journal_title：Frontiers in pediatrics

authors： Zhou Q,Wang D,Wang C,Zheng B,Liu Q,Zhu Z,Jia Z,Gu W

更新日期：2020-07-24 00:00:00

abstract：:Introduction: Childhood growth is a sensitive marker of health. Animal studies show increased height and weight velocity in the presence of fungal as well as antibiotic supplement in feed. Human studies on early gut microbiota and anthropometrics have mainly focused on bacteria only and overweight, with diverging resu...

journal_title：Frontiers in pediatrics

authors： Schei K,Simpson MR,Avershina E,Rudi K,Øien T,Júlíusson PB,Underhill D,Salamati S,Ødegård RA

更新日期：2020-11-09 00:00:00

abstract：:Background: Childhood refractory mycoplasma pneumoniae (MP) pneumonia (RMPP) is a lung disease with elevated level of C-reactive protein and severe clinical and radiological deterioration. Whether bacterial co-infection contributes to disease of RMPP and whether inclusion of non-anti-MP antibiotics in treatment regime...

journal_title：Frontiers in pediatrics

authors： Liu JR,Lu J,Dong F,Li HM,Liu H,Tang XL,Guo YL,Zhao SY

更新日期：2018-10-26 00:00:00

abstract：:Oxidative stress results from excessive reactive oxygen species formation and/or inadequate antioxidant defense. Premature and critically ill infants are especially susceptible due to an immature intrinsic antioxidant system that cannot fully compensate for a free radical load. Oxidative stress is also associated with...

journal_title：Frontiers in pediatrics

authors： Stefanov G,Briyal S,Pais G,Puppala B,Gulati A

更新日期：2020-06-02 00:00:00

abstract：:Cystic kidney diseases comprise a varied collection of hereditary disorders, where renal cysts comprise a major element of their pleiotropic phenotype. In pediatric patients, the term polycystic kidney disease (PKD) commonly refers to two specific hereditary diseases, autosomal recessive polycystic kidney disease (ARP...

journal_title：Frontiers in pediatrics

authors： Sweeney WE Jr,Avner ED

更新日期：2017-04-19 00:00:00

abstract：:Bronchial asthma is one of the most common chronic inflammatory diseases of the airways. In the pathogenesis of this disease, the interplay among the genes, intrinsic, and extrinsic factors are crucial. Various combinations of the involved factors determine and modify the final clinical phenotype/endotype of asthma. O...

journal_title：Frontiers in pediatrics

authors： Jesenak M,Zelieskova M,Babusikova E

更新日期：2017-07-24 00:00:00

abstract：:Non-cystic fibrosis bronchiectasis (NCFB) has gained renewed interest, due to its increasing health-care burden. Annual mortality statistics in England and Wales showed that under 1,000 people die from bronchiectasis each year, and this number is increasing by 3% yearly. Unfortunately, there is a severe lack of well-p...

journal_title：Frontiers in pediatrics

authors： Nathan AM,de Bruyne JA,Eg KP,Thavagnanam S

更新日期：2017-04-24 00:00:00

abstract：:Hypotonia-Cystinuria syndrome (HCS) is a rare disease, caused by a mutation in two contiguous genes (SLC3A1 and PREPL) localized on chromosome 2p21, and it is characterized by both renal involvement with cystine stones and nervous involvement with hypotonia. We here describe a 2 years old child with HCS associated wit...

journal_title：Frontiers in pediatrics

authors： Taroni F,Capone V,Berrettini A,De Marco EA,Manzoni GA,Montini G

更新日期：2019-04-09 00:00:00

abstract：:In recent decades, new research into the developmental defects and pathophysiological basis of congenital diaphragmatic hernia (CDH) has revealed opportunities for the development of innovative therapies. Importantly, the use of animal models to represent this anomaly in the laboratory has resulted in the discovery of...

journal_title：Frontiers in pediatrics

authors： Chiu PP

更新日期：2014-04-29 00:00:00

abstract：:Pontocerebellar hypoplasia (PCH) type 2 is a very rare autosomal recessive neurodegenerative disorder with prenatal onset that disrupts brain development. We present three patients (two siblings and one unrelated child) with PCH 2 linked to the most common mutation c.919G > T (p.Ala307Ser) in TSEN54 gene. The disease ...

journal_title：Frontiers in pediatrics

authors： Pacheva IH,Todorov T,Ivanov I,Tartova D,Gaberova K,Todorova A,Dimitrova D

更新日期：2018-01-23 00:00:00