Investigating Pregnancy and Its Complications Using Circulating Cell-Free RNA in Women's Blood During Gestation.

abstract：:Objective: The primary goal of this study was to assess current maintenance intravenous fluid (mIVF) prescribing practices of pediatric hospitalists after the release of the American Academy of Pediatrics Clinical Practice Guideline (AAP CPG), specifically assessing the rates of various isotonic vs. hypotonic solution...

journal_title：Frontiers in pediatrics

authors： Hall AM,Ayus JC,Moritz ML

更新日期：2020-01-15 00:00:00

abstract：:During early post-natal life, neonates must adjust to the transition from the sheltered intra-uterine environment to the microbe-laden external world, wherein they encounter a constellation of antigens and the colonization by the microbiome. At this vulnerable stage, neonatal immune responses are considered immature a...

journal_title：Frontiers in pediatrics

authors： Tsafaras GP,Ntontsi P,Xanthou G

更新日期：2020-01-28 00:00:00

abstract：:Perianal abscess and fistula-in-ano are well-described in the pediatric population. They are most common in infants less than 1 year of age and often resolve with oral antibiotics; occasionally they require drainage or fistulotomy. The etiology is commonly associated with cryptoglandular obstruction and subsequent inf...

journal_title：Frontiers in pediatrics

authors： Barry WE,Asuelime GE,Zhou S,Hammoudeh J,Ford HR,Kim ES

更新日期：2018-05-16 00:00:00

abstract：:Objective: In many patients with congenital heart disease (CHD) arterial blood flow to the arms is inhibited due to shunt surgery in infancy. This study investigates the handgrip strength of patients with CHD in regard to previous shunt procedures. Patients and Methods: Handgrip was evaluated in 424 patients with vari...

journal_title：Frontiers in pediatrics

authors： Müller J,Röttgers L,Neidenbach RC,Oberhoffer R,Ewert P,Hager A

更新日期：2018-09-06 00:00:00

abstract：:A 3-year-old girl was admitted to our hospital for the correction of atrial septal defect (ASD). Open heart operation with cardiopulmonary bypass is dangerous because the patient also had hereditary spherocytosis, which put her at risk for hemolytic anemia. Therefore, percutaneous transcatheter closure for ASD was cho...

journal_title：Frontiers in pediatrics

authors： Ji Z,Liu N,Du Z,Luo G,Bing Z,Xing Q,Pan S

更新日期：2019-12-17 00:00:00

abstract：:Pertussis, caused by Bordetella (B.) pertussis, a Gram-negative bacterium, is a highly contagious airway infection. Especially in infants, pertussis remains a major health concern. Acute infection with B. pertussis can cause severe illness characterized by severe respiratory failure, pulmonary hypertension, leucocytos...

journal_title：Frontiers in pediatrics

authors： Zlamy M

更新日期：2016-06-08 00:00:00

abstract：:The concept of orthostatic hypertension in children was first proposed in 2012. The pathogenesis is not clear by now. Orthostatic hypertension is one of the important causes of orthostatic intolerance in children and is related to the development of essential hypertension in the future. It is commonly seen in older ch...

journal_title：Frontiers in pediatrics

authors： Hu Y,Jin H,Du J

更新日期：2020-07-29 00:00:00

abstract：:Objectives: Empirical assessment of parental needs and affecting factors for counseling success after prenatal diagnosis of congenital heart disease (CHD). Methods:Counseling success after fetal diagnosis of CHD was assessed by a validated standardized questionnaire. The dependent variable "Effective Counseling" was m...

journal_title：Frontiers in pediatrics

authors： Kovacevic A,Simmelbauer A,Starystach S,Elsässer M,Müller A,Bär S,Gorenflo M

更新日期：2020-02-26 00:00:00

abstract：:Ceftolozane-tazobactam is a novel fifth-generation cephalosporin/β-lactamase inhibitor combination recently approved for treatment of both complicated intra-abdominal and urinary tract infections in adults. Considering its potent bactericidal activity against Pseudomonas aeruginosa, it might represent an important opt...

journal_title：Frontiers in pediatrics

authors： Garazzino S,Altieri E,Silvestro E,Pruccoli G,Scolfaro C,Bignamini E

更新日期：2020-05-05 00:00:00

abstract：:Nowadays, food allergies are considered as a wide spectrum of disorders that need different approaches. The "one size fits all" approach is giving way to a "targeted approach," based on the identification of the patient's phenotype. Thus, the approach of nutritional management of food allergy has moved on from simply ...

journal_title：Frontiers in pediatrics

authors： D'Auria E,Pendezza E,Zuccotti GV

更新日期：2020-03-27 00:00:00

abstract：:Kawasaki disease (KD) is a pediatric vasculitis syndrome that is often involves coronary artery lesions (e. g., coronary artery aneurysms). Although its causal factors and entire pathogenesis remain elusive, the available evidence indicates that the pathogenesis of KD is closely associated with dysregulation of immune...

journal_title：Frontiers in pediatrics

authors： Nakamura A,Ikeda K,Hamaoka K

更新日期：2019-06-28 00:00:00

abstract：:Deficiency of adenosine deaminase 2 (DADA2) is a monogenic form of systemic vasculopathy that often presents during early childhood. Linked to biallelic mutations in ADA2 (previously CECR1), DADA2 was initially described as a syndrome of recurrent fever, livedo racemosa, early-onset strokes, and peripheral vasculopath...

journal_title：Frontiers in pediatrics

authors： Lee PY

更新日期：2018-10-18 00:00:00

abstract：:Although antibiotics confer significant health benefits in treating or preventing bacterial infections, an accumulating wealth of evidence illustrates their detrimental effect on host-microbiota homeostasis, posing a serious menace to the global public health. In recent years, it is becoming evident that infants, who ...

journal_title：Frontiers in pediatrics

authors： Shekhar S,Petersen FC

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) is frequently associated with an increase in sympathetic tone. This may adversely affect cardiac autonomic control. Knowledge about the clinical impact of autonomic dysfunction in patients with PH is limited. We aimed to assess whether parameters of heart rate variability (HRV) ar...

journal_title：Frontiers in pediatrics

authors： Latus H,Bandorski D,Rink F,Tiede H,Siaplaouras J,Ghofrani A,Seeger W,Schranz D,Apitz C

更新日期：2015-07-07 00:00:00

abstract：:Background: High parent education is protective against youth health risk behaviors such as tobacco use. According to the Minorities' Diminished Returns theory, however, higher parent education seems to exert less protection for the ethnic minority relative to the majority groups. Objectives: To explore ethnic differe...

journal_title：Frontiers in pediatrics

authors： Assari S,Boyce S,Caldwell CH,Bazargan M

更新日期：2020-08-19 00:00:00

abstract：:Neonatal encephalopathy (NE) is associated with high mortality and morbidity. Factors predisposing to NE can be antenatal, perinatal, or a combination of both. Antenatal maternal factors, familial factors, genetic predisposition, hypoxic ischemic encephalopathy, infections, placental abnormalities, thrombophilia, coag...

journal_title：Frontiers in pediatrics

authors： Aslam S,Strickland T,Molloy EJ

更新日期：2019-04-16 00:00:00

abstract：:Introduction: Emergency vascular access is rarely required during neonatal resuscitation. We aimed to analyze frequency of use, success, and complication rates of intraosseous (IO) vascular access in neonates at a single tertiary neonatal intensive care unit. Method: We performed a questionnaire-based survey among ped...

journal_title：Frontiers in pediatrics

authors： Mileder LP,Urlesberger B,Schwaberger B

更新日期：2020-09-18 00:00:00

abstract：:Chronic granulomatous disease (CGD) is an inherited, genetically heterogeneous disease characterized by defective phagocytic cell microbicidal function, leading to increased susceptibility to bacterial and fungal infections. CGD is caused by mutations in components of the nicotinamide adenine dinucleotide phosphate (N...

journal_title：Frontiers in pediatrics

authors： de Albuquerque JAT,Lima AM,de Oliveira Junior EB,Ishizuka EK,Aragão-Filho WC,Bengala Zurro N,Mayumi Chiba S,Fernandes FR,Condino-Neto A

更新日期：2019-09-27 00:00:00

abstract：:In recent decades, new research into the developmental defects and pathophysiological basis of congenital diaphragmatic hernia (CDH) has revealed opportunities for the development of innovative therapies. Importantly, the use of animal models to represent this anomaly in the laboratory has resulted in the discovery of...

journal_title：Frontiers in pediatrics

authors： Chiu PP

更新日期：2014-04-29 00:00:00

abstract：:Asthma is the most common chronic disease in children. As suggested by international guidelines, the main goals of asthma treatment are symptoms control and lung function preservation, through a stepwise and control-based approach. The first line therapy based on inhaled corticosteroids may fail to reach control in mo...

journal_title：Frontiers in pediatrics

authors： Maglione M,Poeta M,Santamaria F

更新日期：2019-01-16 00:00:00

abstract：:Autosomal dominant polycystic kidney disease (ADPKD) affects 1 in 400 to 1,000 live births, making it the most common monogenic cause of renal failure. Although no definite cure is available yet, it is important to affect disease progression by influencing modifiable factors such as hypertension and proteinuria. Besid...

journal_title：Frontiers in pediatrics

authors： De Rechter S,Breysem L,Mekahli D

更新日期：2017-12-20 00:00:00

abstract：:Thrombocytopenia and pancytopenia, occurring in patients with Fanconi anemia (FA), are interpreted either as progression to bone marrow failure or as developing myelodysplasia. On the other hand, immune thrombocytopenia (ITP) represents an acquired and often self-limiting benign hematologic disorder, associated with p...

journal_title：Frontiers in pediatrics

authors： Karastaneva A,Lanz S,Wawer A,Behrends U,Schindler D,Dietrich R,Burdach S,Urban C,Benesch M,Seidel MG

更新日期：2015-06-08 00:00:00

abstract：:Background: The occurrence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated coronavirus disease 2019 (COVID-19) have profoundly affected adult kidney disease patients. In contrast, pediatric solid organ transplant recipients, including pediatric kidney transplant (KT) recipients, ...

journal_title：Frontiers in pediatrics

authors： Nailescu C,Khalid M,Wilson AC,Amanat F,Arregui S,Canas J,Hooks J,Krammer F,Schwaderer AL,Hains DS

更新日期：2020-10-30 00:00:00

abstract：:Background: Although most preterm infants breathe at birth, their respiratory drive is weak and supplemental oxygen is often needed to overcome hypoxia. This could in turn lead to hyperoxia. To reduce the risk of hyperoxia, currently an initial low oxygen concentration (21-30%) is recommended during stabilization at b...

journal_title：Frontiers in pediatrics

authors： Dekker J,Hooper SB,Giera M,McGillick EV,Hutten GJ,Onland W,van Kaam AH,Te Pas AB

更新日期：2019-05-07 00:00:00

abstract：BACKGROUND:Although histologic chorioamnionitis (HCA) is known to be associated with poor outcomes in preterm infants, its clinical significance among term infants is not clearly known. OBJECTIVES:To investigate the utility of HCA in determining early onset clinical sepsis (EOCS) among term newborns. METHODS:The inci...

journal_title：Frontiers in pediatrics

authors： Cuna A,Hakima L,Tseng YA,Fornier B,Islam S,Quintos-Alagheband ML,Khullar P,Weinberger B,Hanna N

更新日期：2014-04-04 00:00:00

abstract：:Asthma is the most frequent chronic disease in children, and its pathogenesis involves genetic, epigenetic, and environmental factors. The rapid rise in the prevalence of asthma registered over the last few decades has stressed the need to identify the environmental and modifiable factors associated with the developme...

journal_title：Frontiers in pediatrics

authors： Trambusti I,Nuzzi G,Costagliola G,Verduci E,D'Auria E,Peroni DG,Comberiati P

更新日期：2020-08-18 00:00:00

abstract：:Severe invasive infections such as brain abscess in a child should prompt an immune evaluation. Specific granule deficiency (SGD) is a rare morphologic neutrophil granular defect characterized by reduced granules within neutrophils, absence of granule proteins, and bilobed nuclei. Patients are susceptible to invasive ...

journal_title：Frontiers in pediatrics

authors： Leszcynska M,Patel B,Morrow M,Chamizo W,Tuite G,Berman DM,Potthast K,Hsu AP,Holland SM,Leiding JW

更新日期：2020-04-22 00:00:00

abstract：Background:Pediatric sepsis causes significant global morbidity and mortality and low- and middle-income countries (LMICs) bear the bulk of the burden. International sepsis guidelines may not be relevant in LMICs, especially in sub-Saharan Africa (SSA), due to resource constraints and population differences. There is a...

journal_title：Frontiers in pediatrics

authors： Kortz TB,Sawe HR,Murray B,Enanoria W,Matthay MA,Reynolds T

更新日期：2017-12-22 00:00:00

abstract：Background:Given the positive influence of responsive caregiving on dietary habits in childhood, to raise awareness of caregivers regarding their behavior is crucial in multidisciplinary care on infant feeding. Objectives:To identify the most common responsive and non-responsive feeding practices in mothers of childre...

journal_title：Frontiers in pediatrics

authors： Machado RHV,Tosatti AM,Malzyner G,Maximino P,Ramos CC,Bozzini AB,Ribeiro L,Fisberg M

更新日期：2018-01-04 00:00:00

abstract：:Response to early intervention programs in autism is variable. However, the factors associated with positive versus poor treatment outcomes remain unknown. Hence the issue of which intervention/s should be chosen for an individual child remains a common dilemma. We argue that lack of knowledge on "what works for whom ...

journal_title：Frontiers in pediatrics

authors： Vivanti G,Prior M,Williams K,Dissanayake C

更新日期：2014-06-20 00:00:00