Immune Thrombocytopenia in Two Unrelated Fanconi Anemia Patients - A Mere Coincidence?

abstract：:Aim: The aim of this study was to present primary outcomes of autologous bone marrow mononuclear cell (BMMNC) transplantation to improve neurological sequelae in four children with intracranial hemorrhage (ICH) incidence during the neonatal period. Methods: GMFM88 and modified Ashworth score were used to assess motor ...

journal_title：Frontiers in pediatrics

authors： Liem NT,Huyen TL,Huong LT,Doan NV,Anh BV,Anh NTP,Tung DT

更新日期：2020-01-24 00:00:00

abstract：:Background: Intussusception is a common abdominal emergency in infancy and childhood, and the recurrence rate is reported to be up to 20%. Numerous potential risk factors for recurrence have been reported, although some of them are still controversial. Objective: The present study was conducted to identify the risk fa...

journal_title：Frontiers in pediatrics

authors： Ye X,Tang R,Chen S,Lin Z,Zhu J

更新日期：2019-04-16 00:00:00

abstract：:Ceftolozane-tazobactam is a novel fifth-generation cephalosporin/β-lactamase inhibitor combination recently approved for treatment of both complicated intra-abdominal and urinary tract infections in adults. Considering its potent bactericidal activity against Pseudomonas aeruginosa, it might represent an important opt...

journal_title：Frontiers in pediatrics

authors： Garazzino S,Altieri E,Silvestro E,Pruccoli G,Scolfaro C,Bignamini E

更新日期：2020-05-05 00:00:00

abstract：:Introduction: Hepatic arteriovenous fistula (HAVF) is an abnormal communication between the hepatic arteries and hepatic veins. This condition is treated mainly using interventional closure and surgery. However, these procedures are associated with many postoperative complications and high mortality. Propranolol and o...

journal_title：Frontiers in pediatrics

authors： Ba H,Xu L,Peng H,Lin Y,Li X,Qin Y,Wang H

更新日期：2020-04-21 00:00:00

abstract：:Introduction: Acute respiratory infections with cough (ARIwC) contribute considerably to childhood morbidity, yet few studies have examined the cost of these illnesses among Australian children. Moreover, of the few studies that have, none are inclusive of Aboriginal and/or Torres Strait Islander children, despite thi...

journal_title：Frontiers in pediatrics

authors： Lovie-Toon YG,McPhail SM,Au-Yeung YT,Hall KK,Chang AB,Vagenas D,Otim ME,O'Grady KF

更新日期：2018-12-03 00:00:00

abstract：:Introduction: Children younger than 2 years have an increased risk of complications associated with tuberculosis (TB) due to the immaturity of the innate and adaptive immune response. We aimed to identify TB clinical presentations and outcomes as well as risk factors for complications in this age group. Materials and ...

journal_title：Frontiers in pediatrics

authors： Soriano-Arandes A,Brugueras S,Rodríguez Chitiva A,Noguera-Julian A,Orcau À,Martín-Nalda A,Millet JP,Vallmanya T,Méndez M,Coll-Sibina M,Mayol L,Clopés A,Pineda V,García L,López N,Calavia O,Rius N,Pérez-Porcuna TM,Soler

更新日期：2019-06-11 00:00:00

abstract：:Sickle cell disease (SCD) is a severe autosomal recessively inherited disorder of the red blood cell characterized by erythrocyte deformation caused by the polymerization of the abnormal hemoglobin, which leads to erythrocyte deformation and triggers downstream pathological changes. These include abnormal rheology, va...

journal_title：Frontiers in pediatrics

authors： Krishnamurti L

更新日期：2021-01-05 00:00:00

abstract：:Background: Mounting evidence suggests that childhood asthma is closely associated with maternal weight before pregnancy and gestational weight gain (GWG), yet the results are not often reproducible. Objectives: We conducted a comprehensive meta-analysis, aiming to evaluate the association of pre-pregnancy maternal ob...

journal_title：Frontiers in pediatrics

authors： Liu S,Zhou B,Wang Y,Wang K,Zhang Z,Niu W

更新日期：2020-04-03 00:00:00

abstract：:In genome science, the advancement in high-throughput sequencing technologies and bioinformatics analysis is facilitating the better understanding of Mendelian and complex trait inheritance. Charting the genetic basis of complex diseases - including pediatric cancer, and interpreting huge amount of next-generation seq...

journal_title：Frontiers in pediatrics

authors： Manwar Hussain MR,Khan A,Ali Mohamoud HS

更新日期：2014-03-03 00:00:00

abstract：:Data regarding the safety of using therapeutic hypothermia (TH) with extracorporeal membrane oxygenation (ECMO) in neonates with both hypoxic ischemic encephalopathy (HIE), and respiratory failure are lacking. TH is not associated with an increased incidence of hemostatic complications, but hypothermia may impair coag...

journal_title：Frontiers in pediatrics

authors： Okulu E,Erdeve O,Pekcici BB,Kendirli T,Eyileten Z,Atasay B,Arsan S

更新日期：2019-03-22 00:00:00

abstract：:In recent years the number of extracorporeal membrane oxygenation (ECMO) cases in neonates has been relatively constant. Future expansion lays in new indications for treatment. Regionalization to high-volume ECMO centers allows for optimal utilization of resources, reduction in costs, morbidity, and mortality. Mobile ...

journal_title：Frontiers in pediatrics

authors： Broman LM

更新日期：2019-08-06 00:00:00

abstract：:Introduction: Current international guidelines strongly recommend catheter removal in case of S. aureus central line-associated bloodstream infection (CLASBI), but a catheter salvage strategy may be considered in children given age-related specificities. No data is available regarding the outcome of this strategy in c...

journal_title：Frontiers in pediatrics

authors： Alby-Laurent F,Lambe C,Ferroni A,Salvi N,Lebeaux D,Le Gouëz M,Castelle M,Moulin F,Nassif X,Lortholary O,Chalumeau M,Toubiana J

更新日期：2019-01-25 00:00:00

abstract：:Oxidative stress results from excessive reactive oxygen species formation and/or inadequate antioxidant defense. Premature and critically ill infants are especially susceptible due to an immature intrinsic antioxidant system that cannot fully compensate for a free radical load. Oxidative stress is also associated with...

journal_title：Frontiers in pediatrics

authors： Stefanov G,Briyal S,Pais G,Puppala B,Gulati A

更新日期：2020-06-02 00:00:00

abstract：Background:Pediatric sepsis causes significant global morbidity and mortality and low- and middle-income countries (LMICs) bear the bulk of the burden. International sepsis guidelines may not be relevant in LMICs, especially in sub-Saharan Africa (SSA), due to resource constraints and population differences. There is a...

journal_title：Frontiers in pediatrics

authors： Kortz TB,Sawe HR,Murray B,Enanoria W,Matthay MA,Reynolds T

更新日期：2017-12-22 00:00:00

abstract：:Bronchiectasis is a complex chronic respiratory condition traditionally characterized by chronic infection, airway inflammation, and progressive decline in lung function. Early diagnosis and intensive treatment protocols can stabilize or even improve the clinical prognosis of children with bronchiectasis. However, und...

journal_title：Frontiers in pediatrics

authors： Pizzutto SJ,Hare KM,Upham JW

更新日期：2017-05-29 00:00:00

abstract：:Introduction: Emergency vascular access is rarely required during neonatal resuscitation. We aimed to analyze frequency of use, success, and complication rates of intraosseous (IO) vascular access in neonates at a single tertiary neonatal intensive care unit. Method: We performed a questionnaire-based survey among ped...

journal_title：Frontiers in pediatrics

authors： Mileder LP,Urlesberger B,Schwaberger B

更新日期：2020-09-18 00:00:00

abstract：:Pontocerebellar hypoplasia (PCH) type 2 is a very rare autosomal recessive neurodegenerative disorder with prenatal onset that disrupts brain development. We present three patients (two siblings and one unrelated child) with PCH 2 linked to the most common mutation c.919G > T (p.Ala307Ser) in TSEN54 gene. The disease ...

journal_title：Frontiers in pediatrics

authors： Pacheva IH,Todorov T,Ivanov I,Tartova D,Gaberova K,Todorova A,Dimitrova D

更新日期：2018-01-23 00:00:00

abstract：:Perianal abscess and fistula-in-ano are well-described in the pediatric population. They are most common in infants less than 1 year of age and often resolve with oral antibiotics; occasionally they require drainage or fistulotomy. The etiology is commonly associated with cryptoglandular obstruction and subsequent inf...

journal_title：Frontiers in pediatrics

authors： Barry WE,Asuelime GE,Zhou S,Hammoudeh J,Ford HR,Kim ES

更新日期：2018-05-16 00:00:00

abstract：:Background: Amount of parenchymal involvement in patients with interstitial pneumonia Covid-19 related, seems to be associated with a worse prognosis. Nowadays 3D reconstruction imaging is expanding its role in clinical medical practice. We aimed to use 3D lung reconstruction of a young lady affected by Sars-CoV2 infe...

journal_title：Frontiers in pediatrics

authors： Borro L,Ciliberti P,Santangelo TP,Magistrelli A,Campana A,Carducci FC,Caterina M,Tomà P,Secinaro A

更新日期：2020-08-05 00:00:00

abstract：:Background: Eculizumab has dramatically changed poor outcomes of complement-mediated atypical hemolytic uremic syndrome (aHUS) as first-line treatment. Discontinuation of eculizumab remains challenging, and doctor's visits every 2 weeks for intravenous injection because of standard dosing protocols is a huge burden. T...

journal_title：Frontiers in pediatrics

authors： Saida K,Fukuda T,Mizuno K,Ogura M,Kamei K,Ito S

更新日期：2019-12-17 00:00:00

abstract：:Cerebral palsy (CP) is the most common cause of disability in childhood. Respiratory illness is the most common cause of mortality, morbidity, and poor quality of life in the most severely affected children. Respiratory illness is caused by multiple and combined factors. This review describes these factors and discuss...

journal_title：Frontiers in pediatrics

authors： Marpole R,Blackmore AM,Gibson N,Cooper MS,Langdon K,Wilson AC

更新日期：2020-06-24 00:00:00

abstract：:Bronchial asthma is one of the most common chronic inflammatory diseases of the airways. In the pathogenesis of this disease, the interplay among the genes, intrinsic, and extrinsic factors are crucial. Various combinations of the involved factors determine and modify the final clinical phenotype/endotype of asthma. O...

journal_title：Frontiers in pediatrics

authors： Jesenak M,Zelieskova M,Babusikova E

更新日期：2017-07-24 00:00:00

abstract：:Although antibiotics confer significant health benefits in treating or preventing bacterial infections, an accumulating wealth of evidence illustrates their detrimental effect on host-microbiota homeostasis, posing a serious menace to the global public health. In recent years, it is becoming evident that infants, who ...

journal_title：Frontiers in pediatrics

authors： Shekhar S,Petersen FC

更新日期：2020-10-15 00:00:00

abstract：:Background: Pulmonary artery banding (PAB) is reported as an innovative strategy for children with end-stage heart failure (ESHF) to bridge to transplantation or recovery. We report our early experience with PAB to evaluate outcomes, indications, and limitations. Materials and Methods: This is a single-center prospect...

journal_title：Frontiers in pediatrics

authors： Di Candia A,Castaldi B,Bordin G,Cerutti A,Reffo E,Biffanti R,Di Salvo G,Vida VL,Padalino MA

更新日期：2020-07-16 00:00:00

abstract：:Response to early intervention programs in autism is variable. However, the factors associated with positive versus poor treatment outcomes remain unknown. Hence the issue of which intervention/s should be chosen for an individual child remains a common dilemma. We argue that lack of knowledge on "what works for whom ...

journal_title：Frontiers in pediatrics

authors： Vivanti G,Prior M,Williams K,Dissanayake C

更新日期：2014-06-20 00:00:00

abstract：:Hypertension after kidney transplant is a frequent occurrence in pediatric patients. It is a risk factor for graft loss and contributes to the significant burden of cardiovascular disease (CVD) in this population. The etiology of posttransplant hypertension is multifactorial including donor factors, recipient factors,...

journal_title：Frontiers in pediatrics

authors： Charnaya O,Moudgil A

更新日期：2017-05-01 00:00:00

abstract：:Neonatal encephalopathy (NE) is associated with high mortality and morbidity. Factors predisposing to NE can be antenatal, perinatal, or a combination of both. Antenatal maternal factors, familial factors, genetic predisposition, hypoxic ischemic encephalopathy, infections, placental abnormalities, thrombophilia, coag...

journal_title：Frontiers in pediatrics

authors： Aslam S,Strickland T,Molloy EJ

更新日期：2019-04-16 00:00:00

abstract：:Introduction: Ventilation causes cerebral white matter inflammation and injury, which is exacerbated by intrauterine inflammation. However, the effects on cortical gray matter are not well-known. Our aim was to examine the effect of ventilation on the cerebral cortex of near-term lambs exposed to intrauterine inflamma...

journal_title：Frontiers in pediatrics

authors： Stojanovska V,Atik A,Nitsos I,Skiöld B,Barton SK,Zahra VA,Rodgers K,Hooper SB,Polglase GR,Galinsky R

更新日期：2018-06-15 00:00:00

abstract：:Asthma is the most common chronic disease in children. As suggested by international guidelines, the main goals of asthma treatment are symptoms control and lung function preservation, through a stepwise and control-based approach. The first line therapy based on inhaled corticosteroids may fail to reach control in mo...

journal_title：Frontiers in pediatrics

authors： Maglione M,Poeta M,Santamaria F

更新日期：2019-01-16 00:00:00

abstract：:Autoimmune Congenital Heart Block (CHB) is an immune-mediated disease due to transplacental passage of circulating anti-Ro/SSA and anti-La/SSB autoantibodies. It occurs in 2% of anti-Ro/SSA-exposed pregnancies, and recurrence rate is nine times higher in subsequent pregnancies. Aim of this review is to identify biomar...

journal_title：Frontiers in pediatrics

authors： De Carolis S,Garufi C,Garufi E,De Carolis MP,Botta A,Tabacco S,Salvi S

更新日期：2020-12-22 00:00:00