Salvage Strategy for Long-Term Central Venous Catheter-Associated Staphylococcus aureus Infections in Children.

abstract：:Chronic granulomatous disease (CGD) is an inherited, genetically heterogeneous disease characterized by defective phagocytic cell microbicidal function, leading to increased susceptibility to bacterial and fungal infections. CGD is caused by mutations in components of the nicotinamide adenine dinucleotide phosphate (N...

journal_title：Frontiers in pediatrics

authors： de Albuquerque JAT,Lima AM,de Oliveira Junior EB,Ishizuka EK,Aragão-Filho WC,Bengala Zurro N,Mayumi Chiba S,Fernandes FR,Condino-Neto A

更新日期：2019-09-27 00:00:00

abstract：:Urolithiasis can affect all children even preschool ones. Diagnostic difficulties in the youngest children are due to the problems in locating pain and determining its character and severity. In keeping with the ALARA (As Low As Reasonably Achievable) protocol, the number of imaging tests possible to perform is very l...

journal_title：Frontiers in pediatrics

authors： Halinski A,Halinski A,Zaniew M,Kudliński B,Soltysiak J,Sobolewski B,Steyaert H

更新日期：2019-09-06 00:00:00

abstract：:Introduction: Mutations in the contactin-associated protein-like 2 (CNTNAP2) gene (MIM#604569) encoding for CASPR2, a cell adhesion protein of the neurexin family, are known to be associated with autism, intellectual disability, and other neuropsychiatric disorders. A set of intronic deletions of CNTNAP2 gene has also...

journal_title：Frontiers in pediatrics

authors： Falsaperla R,Pappalardo XG,Romano C,Marino SD,Corsello G,Ruggieri M,Parano E,Pavone P

更新日期：2020-09-11 00:00:00

abstract：:A variety of surgical techniques exist for the management of urolithiasis. Minimally invasive techniques have replaced open surgery in the last few decades. For complex stone management, robotic-assisted laparoscopic surgery (RALS) has emerged as a safe and feasible alternative in adults. The literature for RALS for u...

journal_title：Frontiers in pediatrics

authors： Ballesteros N,Snow ZA,Moscardi PRM,Ransford GA,Gomez P,Castellan M

更新日期：2019-08-22 00:00:00

abstract：:Background: Craniofrontonasal syndrome is a rare, X-linked disorder in which heterozygous females ironically reported the majority of patients and is caused by in the EFNB1 gene located at chromosome Xq13.1. Unlike previous reports, we present a female infant with a de novo EFNB1 missense mutation that was demonstrate...

journal_title：Frontiers in pediatrics

authors： Han JY,Kim HJ,Jang JH,Lee IG,Park J

更新日期：2020-09-01 00:00:00

abstract：:Informed consent is a process ensuring that subjects enrolled in research are appropriately informed of the risks and benefits. While this process is well-defined when it is possible and practical to obtain consent prior to the research intervention, it can be less clear in cases of deferred or waived consent. Definin...

journal_title：Frontiers in pediatrics

authors： Rich WD,Katheria AC

更新日期：2019-11-26 00:00:00

abstract：:Asthma is the most common chronic disease in children. As suggested by international guidelines, the main goals of asthma treatment are symptoms control and lung function preservation, through a stepwise and control-based approach. The first line therapy based on inhaled corticosteroids may fail to reach control in mo...

journal_title：Frontiers in pediatrics

authors： Maglione M,Poeta M,Santamaria F

更新日期：2019-01-16 00:00:00

abstract：:Asthma is no longer considered a single disease, but a common label for a set of heterogeneous conditions with shared clinical symptoms but associated with different cellular and molecular mechanisms. Several wheezing phenotypes coexist at preschool age but not all preschoolers with recurrent wheezing develop asthma a...

journal_title：Frontiers in pediatrics

authors： Castro-Rodriguez JA,Cifuentes L,Martinez FD

更新日期：2019-07-31 00:00:00

abstract：:Severe accidental hypothermia has been demonstrated to affect ventricular systolic and diastolic functions, and rewarming might be responsible of cardiovascular collapse. Until now, there have been only a few reports on severe accidental hypothermia, none of which involved children. Herein, we describe here a rare cas...

journal_title：Frontiers in pediatrics

authors： Vicinanza A,De Laet C,Rooze S,Willems A,Beretta-Piccoli X,Vens D,Voglet C,Jacquemart C,Massin M,Biarent D

更新日期：2019-03-29 00:00:00

abstract：:The association between atopic diseases is well known, and previous research has shown that having one atopic disease can predispose to having another. The link between asthma and food allergy has been well researched, but the exact relationship between the two atopic conditions is not fully understood. Food allergic ...

journal_title：Frontiers in pediatrics

authors： Foong RX,du Toit G,Fox AT

更新日期：2017-05-09 00:00:00

abstract：:Introduction: Hepatic arteriovenous fistula (HAVF) is an abnormal communication between the hepatic arteries and hepatic veins. This condition is treated mainly using interventional closure and surgery. However, these procedures are associated with many postoperative complications and high mortality. Propranolol and o...

journal_title：Frontiers in pediatrics

authors： Ba H,Xu L,Peng H,Lin Y,Li X,Qin Y,Wang H

更新日期：2020-04-21 00:00:00

abstract：:Introduction: Children younger than 2 years have an increased risk of complications associated with tuberculosis (TB) due to the immaturity of the innate and adaptive immune response. We aimed to identify TB clinical presentations and outcomes as well as risk factors for complications in this age group. Materials and ...

journal_title：Frontiers in pediatrics

authors： Soriano-Arandes A,Brugueras S,Rodríguez Chitiva A,Noguera-Julian A,Orcau À,Martín-Nalda A,Millet JP,Vallmanya T,Méndez M,Coll-Sibina M,Mayol L,Clopés A,Pineda V,García L,López N,Calavia O,Rius N,Pérez-Porcuna TM,Soler

更新日期：2019-06-11 00:00:00

abstract：:Fetal sex is associated with striking differences during in utero development, fetal-to-neonatal transition, and postnatal morbidity and mortality. Male sex fetuses are apparently protected while in utero resulting in a higher secondary sex rate for males than for females. However, during fetal-to-neonatal transition ...

journal_title：Frontiers in pediatrics

authors： Lorente-Pozo S,Parra-Llorca A,Torres B,Torres-Cuevas I,Nuñez-Ramiro A,Cernada M,García-Robles A,Vento M

更新日期：2018-04-23 00:00:00

abstract：:Data regarding the safety of using therapeutic hypothermia (TH) with extracorporeal membrane oxygenation (ECMO) in neonates with both hypoxic ischemic encephalopathy (HIE), and respiratory failure are lacking. TH is not associated with an increased incidence of hemostatic complications, but hypothermia may impair coag...

journal_title：Frontiers in pediatrics

authors： Okulu E,Erdeve O,Pekcici BB,Kendirli T,Eyileten Z,Atasay B,Arsan S

更新日期：2019-03-22 00:00:00

abstract：:Background: Although WU polyomavirus (WU) and KI polyomavirus (KI) have been demonstrated to infect the human respiratory tract, it remains unclear if WU or KI cause human disease. We sought to further investigate the relationship between WU and KI infection and respiratory disease in a pediatric population with respi...

journal_title：Frontiers in pediatrics

authors： Hansen-Estruch C,Coleman KK,Thoon KC,Low JG,Anderson BD,Gray GC

更新日期：2018-08-17 00:00:00

abstract：:Background: The occurrence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated coronavirus disease 2019 (COVID-19) have profoundly affected adult kidney disease patients. In contrast, pediatric solid organ transplant recipients, including pediatric kidney transplant (KT) recipients, ...

journal_title：Frontiers in pediatrics

authors： Nailescu C,Khalid M,Wilson AC,Amanat F,Arregui S,Canas J,Hooks J,Krammer F,Schwaderer AL,Hains DS

更新日期：2020-10-30 00:00:00

abstract：:The evaluation and treatment of the heterogeneous group of kidney diseases poses a challenging field in pediatrics. Many of the pediatric disorders resulting in severe renal affection are exceedingly rare and therapeutic approaches have remained symptomatic for most of these disease entities. The insights obtained fro...

journal_title：Frontiers in pediatrics

authors： Liebau MC

更新日期：2014-07-01 00:00:00

abstract：:Systemic inflammation and duration of immobilization are strong independent risk factors for the development of intensive care unit-acquired weakness (ICUAW). Activation of the pro-inflammatory transcription factor nuclear factor-κB (NF-κB) results in muscle wasting during disuse-induced skeletal muscle atrophy (ICU b...

journal_title：Frontiers in pediatrics

authors： Meduri GU,Schwingshackl A,Hermans G

更新日期：2016-08-02 00:00:00

abstract：:Background: Optimal timing for resection of asymptomatic congenital lung malformations (CLMs) remains controversial. The aim of this study is to define optimal timing for surgical intervention of patients with CLMs and define clinical variables that affect surgical outcomes. Methods: An IRB-approved retrospective anal...

journal_title：Frontiers in pediatrics

authors： Duron V,Zenilman A,Griggs C,DeFazio J,Price JC,Fan W,Vivero M,Castrillon J,Schmaedick M,Iqbal E,Rothenberg S

更新日期：2020-02-14 00:00:00

abstract：:Objective: 11β-hydroxylase deficiency (11βOHD) is a rare autosomal recessive disorder caused by mutations in the CYP11B1 gene. It is characterized by virilization, hypertension, and significant final height impairment. In this study, we aim to investigate the clinical and molecular characteristics of four unrelated Ch...

journal_title：Frontiers in pediatrics

authors： Zhou Q,Wang D,Wang C,Zheng B,Liu Q,Zhu Z,Jia Z,Gu W

更新日期：2020-07-24 00:00:00

abstract：:Ceftolozane-tazobactam is a novel fifth-generation cephalosporin/β-lactamase inhibitor combination recently approved for treatment of both complicated intra-abdominal and urinary tract infections in adults. Considering its potent bactericidal activity against Pseudomonas aeruginosa, it might represent an important opt...

journal_title：Frontiers in pediatrics

authors： Garazzino S,Altieri E,Silvestro E,Pruccoli G,Scolfaro C,Bignamini E

更新日期：2020-05-05 00:00:00

abstract：:Cerebral palsy (CP) is the most common cause of disability in childhood. Respiratory illness is the most common cause of mortality, morbidity, and poor quality of life in the most severely affected children. Respiratory illness is caused by multiple and combined factors. This review describes these factors and discuss...

journal_title：Frontiers in pediatrics

authors： Marpole R,Blackmore AM,Gibson N,Cooper MS,Langdon K,Wilson AC

更新日期：2020-06-24 00:00:00

abstract：Background:Acute respiratory illnesses with cough (ARIwC) are predominant causes of morbidity in Australian Indigenous children; however, data on disease burden in urban communities are scarce. This study aimed to determine the incidence of ARIwC, the predictors of recurrent (≥4 episodes) ARIwC, and development of chro...

journal_title：Frontiers in pediatrics

authors： Hall KK,Chang AB,Anderson J,Arnold D,Goyal V,Dunbar M,Otim M,O'Grady KF

更新日期：2017-10-31 00:00:00

abstract：:High-pressure processing (HPP) is a non-thermal technology that is being increasingly applied in food industries worldwide. It was proposed that this method could be used as an alternative to holder pasteurization (HoP; 62.5°C, 30 min) in milk banks but its impact on the immunologic, enzymatic and hormonal components ...

journal_title：Frontiers in pediatrics

authors： Wesolowska A,Sinkiewicz-Darol E,Barbarska O,Strom K,Rutkowska M,Karzel K,Rosiak E,Oledzka G,Orczyk-Pawiłowicz M,Rzoska S,Borszewska-Kornacka MK

更新日期：2018-11-16 00:00:00

abstract：Background:This study aimed to assess the prevalence of picky eating among preschool children and to evaluate the association between eating behavior and growth, physical activity, development, and health status. Methods:A structured questionnaire was used to conduct a cross-sectional descriptive study of 300 primary ...

journal_title：Frontiers in pediatrics

authors： Chao HC

更新日期：2018-02-12 00:00:00

abstract：:Objective: To examine the understanding of the concept peak oxygen uptake (peak VO2) among children and adolescents at different ages from a developmental perspective. Methods: A total of 549 children and adolescents aged 8 to 16 were recruited and instructed to fill in a 20-item Peak VO2Understanding Inventory develo...

journal_title：Frontiers in pediatrics

authors： Wong SWL,Yu CCW,Li AM

更新日期：2021-01-14 00:00:00

abstract：:During early post-natal life, neonates must adjust to the transition from the sheltered intra-uterine environment to the microbe-laden external world, wherein they encounter a constellation of antigens and the colonization by the microbiome. At this vulnerable stage, neonatal immune responses are considered immature a...

journal_title：Frontiers in pediatrics

authors： Tsafaras GP,Ntontsi P,Xanthou G

更新日期：2020-01-28 00:00:00

abstract：:Objective: In many patients with congenital heart disease (CHD) arterial blood flow to the arms is inhibited due to shunt surgery in infancy. This study investigates the handgrip strength of patients with CHD in regard to previous shunt procedures. Patients and Methods: Handgrip was evaluated in 424 patients with vari...

journal_title：Frontiers in pediatrics

authors： Müller J,Röttgers L,Neidenbach RC,Oberhoffer R,Ewert P,Hager A

更新日期：2018-09-06 00:00:00

abstract：:Introduction: Inborn errors of primary bile acid (BA) synthesis are rare autosomal recessive disorders responsible for 1-2% of cases of neonatal cholestasis. Among them, cerebrotendinous xanthomatosis (CTX) is caused by mutations in the CYP27A1 gene resulting in the impairment of sterol 27-hydroxylase enzyme activity....

journal_title：Frontiers in pediatrics

authors： Lipiński P,Klaudel-Dreszler M,Ciara E,Jurkiewicz D,Płoski R,Cielecka-Kuszyk J,Socha P,Jankowska I

更新日期：2021-01-13 00:00:00

abstract：:Selective attention and efficacy are important components of scholastic performance in school children. While attempts are being made to introduce new methods to improve academic performance either as part of curricular or extracurricular activities in schools, the success rates are minimal. Hence, this study assessed...

journal_title：Frontiers in pediatrics

authors： Das M,Deepeshwar S,Subramanya P,Manjunath NK

更新日期：2016-06-15 00:00:00