Waived Consent in Perinatal/Neonatal Research-When Is It Appropriate?

abstract：:Thrombocytopenia and pancytopenia, occurring in patients with Fanconi anemia (FA), are interpreted either as progression to bone marrow failure or as developing myelodysplasia. On the other hand, immune thrombocytopenia (ITP) represents an acquired and often self-limiting benign hematologic disorder, associated with p...

journal_title：Frontiers in pediatrics

authors： Karastaneva A,Lanz S,Wawer A,Behrends U,Schindler D,Dietrich R,Burdach S,Urban C,Benesch M,Seidel MG

更新日期：2015-06-08 00:00:00

abstract：:[This corrects the article on p. 82 in vol. 5, PMID: 28484690.]. ...

journal_title：Frontiers in pediatrics

authors： Tsabouri S,Mavroudi A,Feketea G,Guibas GV

更新日期：2017-09-11 00:00:00

abstract：:The term osteopetrosis describes a group of rare hereditary diseases of the skeleton, characterized by an increase in bone density, caused by a defect in the development or function of osteoclasts. It comprises a clinically and genetically heterogeneous conditions ranging from infantile onset life-threatening forms to...

journal_title：Frontiers in pediatrics

authors： di Palmo E,Gallucci M,Tronconi E,Bergamaschi R,Cazzato S,La Scola C,Ricci G,Pession A

更新日期：2018-07-31 00:00:00

abstract：Background:This study aimed to assess the prevalence of picky eating among preschool children and to evaluate the association between eating behavior and growth, physical activity, development, and health status. Methods:A structured questionnaire was used to conduct a cross-sectional descriptive study of 300 primary ...

journal_title：Frontiers in pediatrics

authors： Chao HC

更新日期：2018-02-12 00:00:00

abstract：:Nowadays, food allergies are considered as a wide spectrum of disorders that need different approaches. The "one size fits all" approach is giving way to a "targeted approach," based on the identification of the patient's phenotype. Thus, the approach of nutritional management of food allergy has moved on from simply ...

journal_title：Frontiers in pediatrics

authors： D'Auria E,Pendezza E,Zuccotti GV

更新日期：2020-03-27 00:00:00

abstract：:Objectives: Mutations in the neuroblastoma-amplified sequence (NBAS) gene were originally described in patients with skeletal dysplasia or isolated liver disease of variable severity. Subsequent publications reported a more complex phenotype. Among multisystemic clinical symptoms, we were particularly interested in th...

journal_title：Frontiers in pediatrics

authors： Khoreva A,Pomerantseva E,Belova N,Povolotskaya I,Konovalov F,Kaimonov V,Gavrina A,Zimin S,Pershin D,Davydova N,Burlakov V,Viktorova E,Roppelt A,Kalinina E,Novichkova G,Shcherbina A

更新日期：2020-09-15 00:00:00

abstract：:Background: Eye exam for Retinopathy of prematurity (ROP) is a painful procedure and pharmacological analgesia might be ineffective. We hypothesized that magnetic auricular acupuncture (MAA) compared to placebo will decrease pain during ROP exam in preterm infants. Methods: Multicentre randomized controlled trial cond...

journal_title：Frontiers in pediatrics

authors： Gan KML,Oei JL,Quah-Smith I,Kamar AA,Lordudass AAD,Liem KD,Lindrea KB,Daly M,Gaunker N,Mangat AK,Yaskina M,Schmölzer GM

更新日期：2020-12-23 00:00:00

abstract：:Background: Abernethy malformation is a rare vascular anomaly of the portal venous system, which is also known as congenital portosystemic shunts (CPSS). The clinical manifestations of this anomaly can be serious, including hepatopulmonary syndrome(HPS), which can lead to significant hypoxemia and cyanosis. Case Prese...

journal_title：Frontiers in pediatrics

authors： Lin Y,Li X,Li S,Ba H,Wang H,Zhu L

更新日期：2020-10-27 00:00:00

abstract：:Introduction: Hemolytic-uremic syndrome (HUS) is a common cause for intrarenal acute kidney injury in childhood. More than 90% of HUS cases are associated with an infection by Shigatoxin-producing Escherichia coli (STEC) whereas the reminder comprises a heterogeneous group (here classified as Non-STEC-HUS). Renal impa...

journal_title：Frontiers in pediatrics

authors： Vaterodt L,Holle J,Hüseman D,Müller D,Thumfart J

更新日期：2018-08-07 00:00:00

abstract：:Excessive oxygen (O2) can cause tissue injury, scarring, aging, and even death. Our laboratory is studying O2-sensing pulmonary neuroendocrine cells (PNECs) and the PNEC-derived product gastrin-releasing peptide (GRP). Reactive oxygen species (ROS) generated from exposure to hyperoxia, ozone, or ionizing radiation (RT...

journal_title：Frontiers in pediatrics

authors： Sunday ME

更新日期：2014-07-18 00:00:00

abstract：:Objective: To identify postnatal risk factors for bronchopulmonary dysplasia (BPD) development in preterm infants with gestational age ≤32 weeks. Methods: Seventy-two preterm infants(30 with BPD and 42 non-BPD controls) admitted in the neonatal intensive care unit (NICU) of the Children's Hospital of Soochow Universit...

journal_title：Frontiers in pediatrics

authors： Ding L,Wang H,Geng H,Cui N,Huang F,Zhu X,Zhu X

更新日期：2020-06-26 00:00:00

abstract：:Background: High parent education is protective against youth health risk behaviors such as tobacco use. According to the Minorities' Diminished Returns theory, however, higher parent education seems to exert less protection for the ethnic minority relative to the majority groups. Objectives: To explore ethnic differe...

journal_title：Frontiers in pediatrics

authors： Assari S,Boyce S,Caldwell CH,Bazargan M

更新日期：2020-08-19 00:00:00

abstract：:Introduction: Anterior lens capsule vascularity (ALCV) is resorbed in the developing fetus from 27 to 35 weeks gestation. In this pilot study, we evaluated the feasibility and validity of combining smartphone ophthalmoscope videos of ALCV and image analysis for gestational age estimation. Methods: ALCV videos were cap...

journal_title：Frontiers in pediatrics

authors： Patel M,Mukherjee D,Farsiu S,Munoz B,Blood AB,Wilson CG,Griffin JB

更新日期：2019-02-20 00:00:00

abstract：:Cystic kidney diseases comprise a varied collection of hereditary disorders, where renal cysts comprise a major element of their pleiotropic phenotype. In pediatric patients, the term polycystic kidney disease (PKD) commonly refers to two specific hereditary diseases, autosomal recessive polycystic kidney disease (ARP...

journal_title：Frontiers in pediatrics

authors： Sweeney WE Jr,Avner ED

更新日期：2017-04-19 00:00:00

abstract：:Neonatal spinal cord injury is a rare complication of birth trauma by difficult delivery. The typical manifestations are often catastrophic, include decreased or absent movement, loss of reflexes, apnea or periodic breathing, and a lack of response to painful stimulation. The outcome is usually fatal or severe, with l...

journal_title：Frontiers in pediatrics

authors： Lee CC,Chou IJ,Chang YJ,Chiang MC

更新日期：2020-09-29 00:00:00

abstract：:A 3-year-old girl was admitted to our hospital for the correction of atrial septal defect (ASD). Open heart operation with cardiopulmonary bypass is dangerous because the patient also had hereditary spherocytosis, which put her at risk for hemolytic anemia. Therefore, percutaneous transcatheter closure for ASD was cho...

journal_title：Frontiers in pediatrics

authors： Ji Z,Liu N,Du Z,Luo G,Bing Z,Xing Q,Pan S

更新日期：2019-12-17 00:00:00

abstract：:Autosomal dominant polycystic kidney disease (ADPKD) affects 1 in 400 to 1,000 live births, making it the most common monogenic cause of renal failure. Although no definite cure is available yet, it is important to affect disease progression by influencing modifiable factors such as hypertension and proteinuria. Besid...

journal_title：Frontiers in pediatrics

authors： De Rechter S,Breysem L,Mekahli D

更新日期：2017-12-20 00:00:00

abstract：:Background: Eculizumab has dramatically changed poor outcomes of complement-mediated atypical hemolytic uremic syndrome (aHUS) as first-line treatment. Discontinuation of eculizumab remains challenging, and doctor's visits every 2 weeks for intravenous injection because of standard dosing protocols is a huge burden. T...

journal_title：Frontiers in pediatrics

authors： Saida K,Fukuda T,Mizuno K,Ogura M,Kamei K,Ito S

更新日期：2019-12-17 00:00:00

abstract：INTRODUCTION:The usefulness of qualitative or quantitative volumetric magnetic resonance imaging (MRI) in early detection of brain structural changes and prediction of adverse outcomes in neonatal illnesses warrants further investigation. Our aim was to correlate certain brain injuries and the brain volume of feeding-r...

journal_title：Frontiers in pediatrics

authors： Kashou NH,Dar IA,El-Mahdy MA,Pluto C,Smith M,Gulati IK,Lo W,Jadcherla SR

更新日期：2017-04-10 00:00:00

abstract：:Introduction: Low-income and racial/ethnic minority preschoolers (aged 2-5 years) are disproportionately affected by obesity and its associated health consequences. Individual-level factors (e.g., diet) and environmental factors (e.g., neighborhood conditions) contribute to these disparities. However, there is limited...

journal_title：Frontiers in pediatrics

authors： Showell NN,Jennings JM,Johnson KA,Perin J,Thornton RLJ

更新日期：2019-01-22 00:00:00

abstract：:Ataxia-telangiectasia (A-T) is an autosomal recessive disorder characterized by neurodegeneration, combined immunodeficiency, and oculocutaneous telangiectasia. The hyper-IgM phenotype of A-T, correlating with a class-switch recombination defect, IgG and IgA deficiency, T helper and B cell lymphopenia, immune dysregul...

journal_title：Frontiers in pediatrics

authors： Szczawińska-Popłonyk A,Ossowska L,Jończyk-Potoczna K

更新日期：2020-11-19 00:00:00

abstract：:This review presents up-to-date understanding of immunotherapy in the treatment of children with allergic asthma. The principal types of allergen immunotherapy (AIT) are subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT). Both of them are indicated for patients with allergic rhinitis and/or asthma, ...

journal_title：Frontiers in pediatrics

authors： Tsabouri S,Mavroudi A,Feketea G,Guibas GV

更新日期：2017-04-21 00:00:00

abstract：:The association between atopic diseases is well known, and previous research has shown that having one atopic disease can predispose to having another. The link between asthma and food allergy has been well researched, but the exact relationship between the two atopic conditions is not fully understood. Food allergic ...

journal_title：Frontiers in pediatrics

authors： Foong RX,du Toit G,Fox AT

更新日期：2017-05-09 00:00:00

abstract：:We report on the results of a literature review regarding the indications and results of operations to increase bladder outlet resistance to achieve dryness in children with neurogenic sphincter incompetence (NSBD). The relative advantages and disadvantages of injection of bulking agents, periurethral slings, bladder ...

journal_title：Frontiers in pediatrics

authors： Ludwikowski BM,Bieda JC,Lingnau A,González R

更新日期：2019-03-26 00:00:00

abstract：:Background: Environmental issues lead to serious health problems in young growing children. This study aims to determine the association between a country's level of environmental health, ecosystem vitality, and prevalence of early childhood caries (ECC). Methods: This was an ecological study. The data for the explana...

journal_title：Frontiers in pediatrics

authors： Folayan MO,El Tantawi M,Schroth RJ,Kemoli AM,Gaffar B,Amalia R,Feldens CA,ECCAG.

更新日期：2020-05-19 00:00:00

abstract：:Non-cystic fibrosis bronchiectasis (NCFB) has gained renewed interest, due to its increasing health-care burden. Annual mortality statistics in England and Wales showed that under 1,000 people die from bronchiectasis each year, and this number is increasing by 3% yearly. Unfortunately, there is a severe lack of well-p...

journal_title：Frontiers in pediatrics

authors： Nathan AM,de Bruyne JA,Eg KP,Thavagnanam S

更新日期：2017-04-24 00:00:00

abstract：:Abdominal lipoblastomas are uncommon soft tissue tumors in children and rarely arise from the mesentery. Due to intraabdominal location and slow growth, these masses can go unnoticed for long periods of time and often found on surgical exploration. We present a case of a 12-year-old male with years of abdominal disten...

journal_title：Frontiers in pediatrics

authors： Squillaro AI,Chow MD,Arias F,Sadimin ET,Lee YH

更新日期：2020-07-24 00:00:00

abstract：:Background: Childhood refractory mycoplasma pneumoniae (MP) pneumonia (RMPP) is a lung disease with elevated level of C-reactive protein and severe clinical and radiological deterioration. Whether bacterial co-infection contributes to disease of RMPP and whether inclusion of non-anti-MP antibiotics in treatment regime...

journal_title：Frontiers in pediatrics

authors： Liu JR,Lu J,Dong F,Li HM,Liu H,Tang XL,Guo YL,Zhao SY

更新日期：2018-10-26 00:00:00

abstract：:Failure of statural growth is one of the major long-term sequelae of chronic kidney disease (CKD) in children. In recent years effective therapeutic strategies have become available that lead to evidence based practice recommendations. To assess the current growth performance of European children and adolescents with ...

journal_title：Frontiers in pediatrics

authors： Behnisch R,Kirchner M,Anarat A,Bacchetta J,Shroff R,Bilginer Y,Mir S,Caliskan S,Paripovic D,Harambat J,Mencarelli F,Büscher R,Arbeiter K,Soylemezoglu O,Zaloszyc A,Zurowska A,Melk A,Querfeld U,Schaefer F,and the 4C S

更新日期：2019-07-05 00:00:00

abstract：:Objective: To evaluate serial ferritin levels measured in the initial 72 h of admission as a biomarker for new and progressive multi organ dysfunction syndrome (NPMODS) and mortality (unfavorable outcomes) in critically ill children with sepsis due to tropical infections. Material and Methods: In this prospective obse...

journal_title：Frontiers in pediatrics

authors： Williams V,Menon N,Bhatia P,Biswal M,Sreedharanunni S,Rawat A,Jayashree M,Nallasamy K

更新日期：2020-12-03 00:00:00