Oxygen, gastrin-releasing Peptide, and pediatric lung disease: life in the balance.

abstract：:A subset of patients with Ataxia-Telangiectasia (A-T) have dramatically reduced levels of IgG, IgA, and IgE with retained or elevated IgM levels. Several reports suggest that these A-T patients with a "hyper-IgM phenotype" (HIgM) suffer more clinical immunologic consequences than other A-T patients. The immunopatholog...

journal_title：Frontiers in pediatrics

authors： Meyer AK,Banks M,Nadasdy T,Clark JJ,Zheng R,Gelfand EW,Abbott JK

更新日期：2019-10-24 00:00:00

abstract：:Systemic inflammation and duration of immobilization are strong independent risk factors for the development of intensive care unit-acquired weakness (ICUAW). Activation of the pro-inflammatory transcription factor nuclear factor-κB (NF-κB) results in muscle wasting during disuse-induced skeletal muscle atrophy (ICU b...

journal_title：Frontiers in pediatrics

authors： Meduri GU,Schwingshackl A,Hermans G

更新日期：2016-08-02 00:00:00

abstract：:We constructed an optimal machine learning (ML) method for predicting intravenous immunoglobulin (IVIG) resistance in children with Kawasaki disease (KD) using commonly available clinical and laboratory variables. We retrospectively collected 98 clinical records of hospitalized children with KD (2-109 months of age). ...

journal_title：Frontiers in pediatrics

authors： Kuniyoshi Y,Tokutake H,Takahashi N,Kamura A,Yasuda S,Tashiro M

更新日期：2020-12-03 00:00:00

abstract：:Background Aim: The aim of this study was to examine the sleep characteristics of children and explore associations with various socio-demographic factors in an area of Greece characterized by cultural diversity. Methods: A questionnaire about children's sleep habits had been distributed to parents of children who vis...

journal_title：Frontiers in pediatrics

authors： Nena E,Cassimos D,Kaditis A,Kourantzi M,Trakada G,Economou NT,Nikolaidis PT,Rosemann T,Knechtle B,Steiropoulos P,Tsalkidis A

更新日期：2020-02-12 00:00:00

abstract：:Nowadays, food allergies are considered as a wide spectrum of disorders that need different approaches. The "one size fits all" approach is giving way to a "targeted approach," based on the identification of the patient's phenotype. Thus, the approach of nutritional management of food allergy has moved on from simply ...

journal_title：Frontiers in pediatrics

authors： D'Auria E,Pendezza E,Zuccotti GV

更新日期：2020-03-27 00:00:00

abstract：:Objective: The effective diagnosis of Mycoplasma pneumoniae (MP) pneumonia (MPP) in children has been hampered by the difficulty of achieving an early diagnosis. The simultaneous amplification and testing (SAT) has the potential for early diagnosis of MP in children. Methods: Of the 1,180 children enrolled in this stu...

journal_title：Frontiers in pediatrics

authors： Li J,Sun L,Wu X,Guo Y,Jiao W,Xiao J,Xu B,Shen A

更新日期：2019-10-25 00:00:00

abstract：:Introduction: Hepatic arteriovenous fistula (HAVF) is an abnormal communication between the hepatic arteries and hepatic veins. This condition is treated mainly using interventional closure and surgery. However, these procedures are associated with many postoperative complications and high mortality. Propranolol and o...

journal_title：Frontiers in pediatrics

authors： Ba H,Xu L,Peng H,Lin Y,Li X,Qin Y,Wang H

更新日期：2020-04-21 00:00:00

abstract：:Recent studies have demonstrated that gut microbiota development is influenced by human biogeographic factors such as race, ethnicity, diet, lifestyle or culture-specific variations, and other environmental influences. However, biogeographic variation in gut microbiota assembly remains largely unexplored in Latin Amer...

journal_title：Frontiers in pediatrics

authors： Chew C,Barros KV,Weffort VRS,Maranhão HS,Laranjeira M,Knol J,Roeselers G,de Morais MB

更新日期：2020-12-07 00:00:00

abstract：:Background: Optimal timing for resection of asymptomatic congenital lung malformations (CLMs) remains controversial. The aim of this study is to define optimal timing for surgical intervention of patients with CLMs and define clinical variables that affect surgical outcomes. Methods: An IRB-approved retrospective anal...

journal_title：Frontiers in pediatrics

authors： Duron V,Zenilman A,Griggs C,DeFazio J,Price JC,Fan W,Vivero M,Castrillon J,Schmaedick M,Iqbal E,Rothenberg S

更新日期：2020-02-14 00:00:00

abstract：:Background: Pulmonary alveolar proteinosis (PAP) is a rare diffuse lung disease. Reports of rare cases of PAP due to Pneumocystis jirovecii (P. jirovecii) exist in infants with immunodeficiency diseases, but no cases have been reported to date in pediatric patients with type 1 hyper-IgM syndrome (HIGM1). Case Presenta...

journal_title：Frontiers in pediatrics

authors： Zhang FZ,Yuan JX,Qin L,Tang LF

更新日期：2020-06-11 00:00:00

abstract：:Purpose: To explore the lung function of bronchopulmonary dysplasia (BPD) in premature infants to guide clinical prevention, early diagnosis and treatment. Methods: Thirty infants with BPD at 4-36 months of corrected gestational age were enrolled and divided into mild BPD and moderate and severe BPD groups. Thirty ful...

journal_title：Frontiers in pediatrics

authors： Chen D,Chen J,Cui N,Cui M,Chen X,Zhu X,Zhu X

更新日期：2020-01-10 00:00:00

abstract：:A 3-year-old girl was admitted to our hospital for the correction of atrial septal defect (ASD). Open heart operation with cardiopulmonary bypass is dangerous because the patient also had hereditary spherocytosis, which put her at risk for hemolytic anemia. Therefore, percutaneous transcatheter closure for ASD was cho...

journal_title：Frontiers in pediatrics

authors： Ji Z,Liu N,Du Z,Luo G,Bing Z,Xing Q,Pan S

更新日期：2019-12-17 00:00:00

abstract：:Dedicator of cytokinesis 8 (DOCK8) deficiency is an autosomal recessive, combined immunodeficiency within the spectrum of hyper-IgE syndromes. Epstein-Barr virus-positive lymphomatoid granulomatosis (LYG) (EBV + LYG) is a rare diagnosis and a previously unreported presentation of DOCK8 deficiency. A 10-year-old girl w...

journal_title：Frontiers in pediatrics

authors： Dimitriades VR,Devlin V,Pittaluga S,Su HC,Holland SM,Wilson W,Dunleavy K,Shah NN,Freeman AF

更新日期：2017-02-28 00:00:00

abstract：:Exertional dyspnea is a common complaint in general pediatric practice. While a high proportion of the general pediatric population has asthma, other diagnoses, including exercise-induced laryngeal obstruction should be considered, especially when asthma therapy is not sufficient to control symptoms. This review descr...

journal_title：Frontiers in pediatrics

authors： Olin JT

更新日期：2019-03-01 00:00:00

abstract：:Although antibiotics confer significant health benefits in treating or preventing bacterial infections, an accumulating wealth of evidence illustrates their detrimental effect on host-microbiota homeostasis, posing a serious menace to the global public health. In recent years, it is becoming evident that infants, who ...

journal_title：Frontiers in pediatrics

authors： Shekhar S,Petersen FC

更新日期：2020-10-15 00:00:00

abstract：:Failure of statural growth is one of the major long-term sequelae of chronic kidney disease (CKD) in children. In recent years effective therapeutic strategies have become available that lead to evidence based practice recommendations. To assess the current growth performance of European children and adolescents with ...

journal_title：Frontiers in pediatrics

authors： Behnisch R,Kirchner M,Anarat A,Bacchetta J,Shroff R,Bilginer Y,Mir S,Caliskan S,Paripovic D,Harambat J,Mencarelli F,Büscher R,Arbeiter K,Soylemezoglu O,Zaloszyc A,Zurowska A,Melk A,Querfeld U,Schaefer F,and the 4C S

更新日期：2019-07-05 00:00:00

abstract：:Background: Maternal diabetes mellitus (DM) increases the risk of fetal, neonatal, and long-term complications in offspring. Although this has been widely known for decades, data are limited regarding the effect of maternal pregestational and gestational diabetes on the subsequent neurodevelopmental outcome of offspri...

journal_title：Frontiers in pediatrics

authors： Lin CH,Lin WD,Chou IC,Lee IC,Hong SY

更新日期：2019-11-04 00:00:00

abstract：:Background: Abernethy malformation is a rare vascular anomaly of the portal venous system, which is also known as congenital portosystemic shunts (CPSS). The clinical manifestations of this anomaly can be serious, including hepatopulmonary syndrome(HPS), which can lead to significant hypoxemia and cyanosis. Case Prese...

journal_title：Frontiers in pediatrics

authors： Lin Y,Li X,Li S,Ba H,Wang H,Zhu L

更新日期：2020-10-27 00:00:00

abstract：:Animal models provide convenient and clinically relevant tools in the research on neurodegenerative diseases. Studies on developmental disorders extensively rely on the use of laboratory rodents. The present mini-review proposes an alternative translational model based on the use of fetal bovine brain tissue. The bovi...

journal_title：Frontiers in pediatrics

authors： Peruffo A,Cozzi B

更新日期：2014-07-10 00:00:00

abstract：:Introduction: Acute respiratory infections with cough (ARIwC) contribute considerably to childhood morbidity, yet few studies have examined the cost of these illnesses among Australian children. Moreover, of the few studies that have, none are inclusive of Aboriginal and/or Torres Strait Islander children, despite thi...

journal_title：Frontiers in pediatrics

authors： Lovie-Toon YG,McPhail SM,Au-Yeung YT,Hall KK,Chang AB,Vagenas D,Otim ME,O'Grady KF

更新日期：2018-12-03 00:00:00

abstract：:Objective: The objective of the study is to test whether the use of edible oil might be an early treatment strategy for reducing button battery-induced esophageal injury. Methods: A button battery was inserted into esophageal segments collected from pigs. The esophageal segments were randomly allotted to one of the fo...

journal_title：Frontiers in pediatrics

authors： Jia W,Zhang B,Xu G,Xie J,Wei H,Shan N,Wang Q,Yin W,Zhao W

更新日期：2020-03-13 00:00:00

abstract：:The burden of asthma in childhood is considerable worldwide, although some populations are much more affected than others. Many attempts have been made by different investigators to identify the factors that could predict asthma development or persistence in childhood. In this review, the relation between atopic sensi...

journal_title：Frontiers in pediatrics

authors： Moustaki M,Loukou I,Tsabouri S,Douros K

更新日期：2017-07-31 00:00:00

abstract：:Background: Despite the pandemic, data are limited regarding COVID-19 infection in pregnant women and newborns. This report aimed to bring new information about presentation that could modify precautionary measures for infants born of mothers with a remote history of COVID-19. Methods: We report two infants with possi...

journal_title：Frontiers in pediatrics

authors： Hascoët JM,Jellimann JM,Hartard C,Wittwer A,Jeulin H,Franck P,Morel O

更新日期：2020-09-29 00:00:00

abstract：:Sarcoidosis (SD) is a systemic granulomatous condition that is especially encountered in young adults and rarely in children, affecting predominantly the lungs and lymph nodes. We report the case of a 14-year-old teenage boy admitted to our clinic for nausea, vomiting, and weight loss. Clinical examination at the time...

journal_title：Frontiers in pediatrics

authors： Mărginean CO,Meliţ LE,Grigorescu G,Puiac C,Simu I

更新日期：2020-08-26 00:00:00

abstract：Background:Pediatric sepsis causes significant global morbidity and mortality and low- and middle-income countries (LMICs) bear the bulk of the burden. International sepsis guidelines may not be relevant in LMICs, especially in sub-Saharan Africa (SSA), due to resource constraints and population differences. There is a...

journal_title：Frontiers in pediatrics

authors： Kortz TB,Sawe HR,Murray B,Enanoria W,Matthay MA,Reynolds T

更新日期：2017-12-22 00:00:00

abstract：:In recent years, there have been major advances in the application of non-invasive techniques to predict pregnancy-related complications, for example by measuring cell-free RNA (cfRNA) in maternal blood. In contrast to cell-free DNA (cfDNA), which is already in clinical use to diagnose fetal aneuploidy, circulating RN...

journal_title：Frontiers in pediatrics

authors： Moufarrej MN,Wong RJ,Shaw GM,Stevenson DK,Quake SR

更新日期：2020-12-14 00:00:00

abstract：:Objective: To investigate the relationship of overnutrition (obese and overweight) with severity of illness in children hospitalized with acute lower respiratory infections (ALRIs), frequency of viral coinfections and leptin levels. Methods: We studied 124 children <2 years old that were hospitalized for ALRI. Nutriti...

journal_title：Frontiers in pediatrics

authors： Arias-Bravo G,Valderrama G,Inostroza J,Reyes-Farías M,Garcia-Diaz DF,Zorondo-Rodríguez F,Fuenzalida LF

更新日期：2020-02-18 00:00:00

abstract：:Background: Histological chorioamnionitis (HCA) is an infection/inflammation of fetal membranes and complicates 5.2-28.5% of all live births. Exposure to HCA can have long-term consequences including abnormal neurodevelopment and an increased risk for allergic disorders and asthma later in childhood. HCA may incite ep...

journal_title：Frontiers in pediatrics

authors： Fong G,Gayen Nee' Betal S,Murthy S,Favara M,Chan JSY,Addya S,Shaffer TH,Greenspan J,Bhandari V,Li D,Rahman I,Aghai ZH

更新日期：2020-08-04 00:00:00

abstract：:In recent years the number of extracorporeal membrane oxygenation (ECMO) cases in neonates has been relatively constant. Future expansion lays in new indications for treatment. Regionalization to high-volume ECMO centers allows for optimal utilization of resources, reduction in costs, morbidity, and mortality. Mobile ...

journal_title：Frontiers in pediatrics

authors： Broman LM

更新日期：2019-08-06 00:00:00

abstract：:We report on the results of a literature review regarding the indications and results of operations to increase bladder outlet resistance to achieve dryness in children with neurogenic sphincter incompetence (NSBD). The relative advantages and disadvantages of injection of bulking agents, periurethral slings, bladder ...

journal_title：Frontiers in pediatrics

authors： Ludwikowski BM,Bieda JC,Lingnau A,González R

更新日期：2019-03-26 00:00:00