Edible Oils Attenuate Button Battery-Induced Injury in Porcine Esophageal Segments.

abstract：:Objective: Intravenous immunoglobulin (IVIG) therapy is a useful first-line treatment for Kawasaki disease (KD); however, 10-20% of patients fail to respond and require additional IVIG. Soluble CD163 (sCD163) is considered a biomarker for macrophage activation. There are no reports measuring serum sCD163 in KD patient...

journal_title：Frontiers in pediatrics

authors： Azuma Y,Suzuki Y,Okada S,Matsuguma C,Wakiguchi H,Ohnishi Y,Furuta T,Miyake A,Yasudo H,Ichihara K,Ohga S,Hasegawa S

更新日期：2020-04-07 00:00:00

abstract：:Background: Primary carnitine deficiency (PCD) is attributed to a variation in the SLC22A5 (OCTN2) gene which encodes the key protein of the carnitine cycle, the OCTN2 carnitine transporter. PCD is typically identified in childhood by either hypoketotic hypoglycemia, or skeletal and cardiac myopathy. The aim of this s...

journal_title：Frontiers in pediatrics

authors： Zhou W,Li H,Huang T,Zhang Y,Wang C,Gu M

更新日期：2019-02-26 00:00:00

abstract：:The evaluation and treatment of the heterogeneous group of kidney diseases poses a challenging field in pediatrics. Many of the pediatric disorders resulting in severe renal affection are exceedingly rare and therapeutic approaches have remained symptomatic for most of these disease entities. The insights obtained fro...

journal_title：Frontiers in pediatrics

authors： Liebau MC

更新日期：2014-07-01 00:00:00

abstract：:Although antibiotics confer significant health benefits in treating or preventing bacterial infections, an accumulating wealth of evidence illustrates their detrimental effect on host-microbiota homeostasis, posing a serious menace to the global public health. In recent years, it is becoming evident that infants, who ...

journal_title：Frontiers in pediatrics

authors： Shekhar S,Petersen FC

更新日期：2020-10-15 00:00:00

abstract：:Background: Placenta shows high transcription levels of human endogenous retroviruses (HERVs) that are overexpressed during embryonic and fetal development. Methods: In order to gather further information on the degree of HERV activation in maternal and fetal tissues we assessed the transcription levels of pol genes o...

journal_title：Frontiers in pediatrics

authors： Bergallo M,Marozio L,Botta G,Tancredi A,Daprà V,Galliano I,Montanari P,Coscia A,Benedetto C,Tovo PA

更新日期：2020-05-14 00:00:00

abstract：:Pontocerebellar hypoplasia (PCH) type 2 is a very rare autosomal recessive neurodegenerative disorder with prenatal onset that disrupts brain development. We present three patients (two siblings and one unrelated child) with PCH 2 linked to the most common mutation c.919G > T (p.Ala307Ser) in TSEN54 gene. The disease ...

journal_title：Frontiers in pediatrics

authors： Pacheva IH,Todorov T,Ivanov I,Tartova D,Gaberova K,Todorova A,Dimitrova D

更新日期：2018-01-23 00:00:00

abstract：:Background: Necrotizing enterocolitis (NEC) is the most common life-threatening gastrointestinal condition among very and extremely preterm infants. Stem cell therapy has shown some promising protective effects in animal models of intestinal injury, including NEC, but no systematic review has yet evaluated the preclin...

journal_title：Frontiers in pediatrics

authors： Villamor-Martinez E,Hundscheid T,Kramer BW,Hooijmans CR,Villamor E

更新日期：2020-12-09 00:00:00

abstract：:We report on the results of a literature review regarding the indications and results of operations to increase bladder outlet resistance to achieve dryness in children with neurogenic sphincter incompetence (NSBD). The relative advantages and disadvantages of injection of bulking agents, periurethral slings, bladder ...

journal_title：Frontiers in pediatrics

authors： Ludwikowski BM,Bieda JC,Lingnau A,González R

更新日期：2019-03-26 00:00:00

abstract：:The solute carrier family 16 member 1 (SLC16A1) gene encodes for monocarboxylate transporter 1 (MCT1) that mediates the movement of monocarboxylates, such as lactate and pyruvate across cell membranes. Inactivating recessive homozygous or heterozygous mutations in the SLC16A1 gene were described in patients with recur...

journal_title：Frontiers in pediatrics

authors： Al-Khawaga S,AlRayahi J,Khan F,Saraswathi S,Hasnah R,Haris B,Mohammed I,Abdelalim EM,Hussain K

更新日期：2019-07-18 00:00:00

abstract：:[This corrects the article on p. 82 in vol. 5, PMID: 28484690.]. ...

journal_title：Frontiers in pediatrics

authors： Tsabouri S,Mavroudi A,Feketea G,Guibas GV

更新日期：2017-09-11 00:00:00

abstract：:Introduction: Allostatic load (AL) refers to the physiological response associated with the burden of chronic stress. Excessive weight is an important source of physiological stress that promotes a detrimental chronic low-inflammation state. In order to define a correlation between cumulative biological dysregulation ...

journal_title：Frontiers in pediatrics

authors： Calcaterra V,Vinci F,Casari G,Pelizzo G,de Silvestri A,De Amici M,Albertini R,Regalbuto C,Montalbano C,Larizza D,Cena H

更新日期：2019-08-07 00:00:00

abstract：Background:This study aimed to assess the prevalence of picky eating among preschool children and to evaluate the association between eating behavior and growth, physical activity, development, and health status. Methods:A structured questionnaire was used to conduct a cross-sectional descriptive study of 300 primary ...

journal_title：Frontiers in pediatrics

authors： Chao HC

更新日期：2018-02-12 00:00:00

abstract：:Background: Amount of parenchymal involvement in patients with interstitial pneumonia Covid-19 related, seems to be associated with a worse prognosis. Nowadays 3D reconstruction imaging is expanding its role in clinical medical practice. We aimed to use 3D lung reconstruction of a young lady affected by Sars-CoV2 infe...

journal_title：Frontiers in pediatrics

authors： Borro L,Ciliberti P,Santangelo TP,Magistrelli A,Campana A,Carducci FC,Caterina M,Tomà P,Secinaro A

更新日期：2020-08-05 00:00:00

abstract：:Pediatric neuro-oncology surgery continues to progress in sophistication, largely driven by advances in technology used to aid the following aspects of surgery: operative planning (advanced MRI techniques including fMRI and DTI), intraoperative navigation [preoperative MRI, intra-operative MRI (ioMRI) and intra-operat...

journal_title：Frontiers in pediatrics

authors： Foster MT,Harishchandra LS,Mallucci C

更新日期：2018-11-01 00:00:00

abstract：:Background Aim: The aim of this study was to examine the sleep characteristics of children and explore associations with various socio-demographic factors in an area of Greece characterized by cultural diversity. Methods: A questionnaire about children's sleep habits had been distributed to parents of children who vis...

journal_title：Frontiers in pediatrics

authors： Nena E,Cassimos D,Kaditis A,Kourantzi M,Trakada G,Economou NT,Nikolaidis PT,Rosemann T,Knechtle B,Steiropoulos P,Tsalkidis A

更新日期：2020-02-12 00:00:00

abstract：:Background: Necrotizing enterocolitis (NEC) is an often-fatal neonatal disease involving intestinal hyperinflammation leading to necrosis. Despite ongoing research, (1) conflicting results and (2) comorbidities of NEC patients make early NEC detection challenging and may complicate therapy development. Most research s...

journal_title：Frontiers in pediatrics

authors： Klinke M,Wiskemann H,Bay B,Schäfer HJ,Pagerols Raluy L,Reinshagen K,Vincent D,Boettcher M

更新日期：2021-01-06 00:00:00

abstract：UNLABELLED:Even though in the corporate world psychological science has been widely used, the formal use of evidence-based psychology in important areas of clinical medicine has been scanty at best. It was the aim of this study to determine the efficacy of a psychologist-led 2-week nurse educator training on the infect...

journal_title：Frontiers in pediatrics

authors： Van Rostenberghe H,Short J,Ramli N,Geok TB,Subramaniam S,Che Yaakob CA,Othman A,Ibrahim NR,Ho J,Mohamed Z,Hasan H

更新日期：2014-11-19 00:00:00

abstract：:Systemic inflammation and duration of immobilization are strong independent risk factors for the development of intensive care unit-acquired weakness (ICUAW). Activation of the pro-inflammatory transcription factor nuclear factor-κB (NF-κB) results in muscle wasting during disuse-induced skeletal muscle atrophy (ICU b...

journal_title：Frontiers in pediatrics

authors： Meduri GU,Schwingshackl A,Hermans G

更新日期：2016-08-02 00:00:00

abstract：:Background: Eculizumab has dramatically changed poor outcomes of complement-mediated atypical hemolytic uremic syndrome (aHUS) as first-line treatment. Discontinuation of eculizumab remains challenging, and doctor's visits every 2 weeks for intravenous injection because of standard dosing protocols is a huge burden. T...

journal_title：Frontiers in pediatrics

authors： Saida K,Fukuda T,Mizuno K,Ogura M,Kamei K,Ito S

更新日期：2019-12-17 00:00:00

abstract：:DNA repair defects are inborn errors of immunity that result in increased apoptosis and oncogenesis. DNA Ligase 4-deficient patients suffer from a wide range of clinical manifestations since early in life, including: microcephaly, dysmorphic facial features, growth failure, developmental delay, mental retardation; hip...

journal_title：Frontiers in pediatrics

authors： Staines Boone AT,Chinn IK,Alaez-Versón C,Yamazaki-Nakashimada MA,Carrillo-Sánchez K,García-Cruz MLH,Poli MC,González Serrano ME,Medina Torres EA,Muzquiz Zermeño D,Forbes LR,Espinosa-Rosales FJ,Espinosa-Padilla SE,Orange JS,Lu

更新日期：2019-01-21 00:00:00

abstract：:Introduction: Surfactant proteins (SP) have been shown to be inherent proteins of the human CNS and are altered during acute and chronic disturbances of CSF circulation. Aim of the study was to examine the changes of surfactant protein concentrations in CSF of preterm babies suffering from intraventricular hemorrhage....

journal_title：Frontiers in pediatrics

authors： Krause M,Härtig W,Mahr CV,Richter C,Schob J,Puchta J,Hoffmann KT,Nestler U,Thome U,Knüpfer M,Gebauer C,Schob S

更新日期：2020-09-25 00:00:00

abstract：:Autosomal recessive polycystic kidney disease (ARPKD) is a rare monogenic disease with a severe phenotype often presenting prenatally or in early childhood. With its obligate renal and hepatic involvement, ARPKD is one of the most important indications for liver and/or kidney transplantation in childhood. Marked pheno...

journal_title：Frontiers in pediatrics

authors： Ebner K,Schaefer F,Liebau MC,ARegPKD Consortium.

更新日期：2017-02-16 00:00:00

abstract：:Therapeutic strategies for severe hand, foot, and mouth disease (HFMD) are currently either inconsequent or deficient in evidence. We retrospectively surveyed HFMD outbreaks in Xiangyang from June 2008 to December 2013. HFMD is staged from I to V according to clinical severity. Severe HFMD is defined as a case involvi...

journal_title：Frontiers in pediatrics

authors： Liu J,Qi J

更新日期：2020-07-10 00:00:00

abstract：:Background: Intussusception is a common abdominal emergency in infancy and childhood, and the recurrence rate is reported to be up to 20%. Numerous potential risk factors for recurrence have been reported, although some of them are still controversial. Objective: The present study was conducted to identify the risk fa...

journal_title：Frontiers in pediatrics

authors： Ye X,Tang R,Chen S,Lin Z,Zhu J

更新日期：2019-04-16 00:00:00

abstract：:Obesity has reached pandemic proportion and represents a major risk for several comorbidities. In addition to metabolic and cardiovascular obesity-related diseases, recent evidence suggested that obesity might affect immune system function. Adipose tissue is considered an endocrine organ that actively secretes cytokin...

journal_title：Frontiers in pediatrics

authors： Umano GR,Pistone C,Tondina E,Moiraghi A,Lauretta D,Miraglia Del Giudice E,Brambilla I

更新日期：2019-11-22 00:00:00

abstract：:Asthma is the most frequent chronic disease in children, and its pathogenesis involves genetic, epigenetic, and environmental factors. The rapid rise in the prevalence of asthma registered over the last few decades has stressed the need to identify the environmental and modifiable factors associated with the developme...

journal_title：Frontiers in pediatrics

authors： Trambusti I,Nuzzi G,Costagliola G,Verduci E,D'Auria E,Peroni DG,Comberiati P

更新日期：2020-08-18 00:00:00

abstract：:In recent decades, new research into the developmental defects and pathophysiological basis of congenital diaphragmatic hernia (CDH) has revealed opportunities for the development of innovative therapies. Importantly, the use of animal models to represent this anomaly in the laboratory has resulted in the discovery of...

journal_title：Frontiers in pediatrics

authors： Chiu PP

更新日期：2014-04-29 00:00:00

abstract：:Introduction: Emergency vascular access is rarely required during neonatal resuscitation. We aimed to analyze frequency of use, success, and complication rates of intraosseous (IO) vascular access in neonates at a single tertiary neonatal intensive care unit. Method: We performed a questionnaire-based survey among ped...

journal_title：Frontiers in pediatrics

authors： Mileder LP,Urlesberger B,Schwaberger B

更新日期：2020-09-18 00:00:00

abstract：:Objectives: In 2014 probiotic supplementation (Lactobacillus acidophilus and Bifidobacterium longum subspecies infantis; InfloranⓇ) was introduced as standard of care to prevent necrotizing enterocolitis (NEC) in extremely preterm infants in Norway. We aimed to evaluate the influence of probiotics and antibiotic thera...

journal_title：Frontiers in pediatrics

authors： Esaiassen E,Hjerde E,Cavanagh JP,Pedersen T,Andresen JH,Rettedal SI,Støen R,Nakstad B,Willassen NP,Klingenberg C

更新日期：2018-11-16 00:00:00

abstract：OBJECTIVES/HYPOTHESIS:Congenital aural atresia is a rare condition affecting 1 in 10,000-20,000 children a year. Surgery is required to restore hearing to facilitate normal development. The objective of this study was to compare outcomes in hearing, complications, and quality of life of surgical reconstruction of the e...

journal_title：Frontiers in pediatrics

authors： Farnoosh S,Mitsinikos FT,Maceri D,Don DM

更新日期：2014-01-22 00:00:00