Recent Progress of the ARegPKD Registry Study on Autosomal Recessive Polycystic Kidney Disease.

abstract：:Urolithiasis can affect all children even preschool ones. Diagnostic difficulties in the youngest children are due to the problems in locating pain and determining its character and severity. In keeping with the ALARA (As Low As Reasonably Achievable) protocol, the number of imaging tests possible to perform is very l...

journal_title：Frontiers in pediatrics

authors： Halinski A,Halinski A,Zaniew M,Kudliński B,Soltysiak J,Sobolewski B,Steyaert H

更新日期：2019-09-06 00:00:00

abstract：:The COVID-19 crisis has pressured hospital-based care for children with high-risk asthma as they have become deprived of regular clinical evaluations. However, COVID-19 also provided important lessons about implementing novel directions for care. Personalized eHealth technology, tailored to the individual and the heal...

journal_title：Frontiers in pediatrics

authors： van der Kamp MR,Tabak M,de Rooij SEJA,van Lierop PPE,Thio BJ

更新日期：2020-09-08 00:00:00

abstract：:Chronic granulomatous disease (CGD) is an inherited, genetically heterogeneous disease characterized by defective phagocytic cell microbicidal function, leading to increased susceptibility to bacterial and fungal infections. CGD is caused by mutations in components of the nicotinamide adenine dinucleotide phosphate (N...

journal_title：Frontiers in pediatrics

authors： de Albuquerque JAT,Lima AM,de Oliveira Junior EB,Ishizuka EK,Aragão-Filho WC,Bengala Zurro N,Mayumi Chiba S,Fernandes FR,Condino-Neto A

更新日期：2019-09-27 00:00:00

abstract：:Data regarding the safety of using therapeutic hypothermia (TH) with extracorporeal membrane oxygenation (ECMO) in neonates with both hypoxic ischemic encephalopathy (HIE), and respiratory failure are lacking. TH is not associated with an increased incidence of hemostatic complications, but hypothermia may impair coag...

journal_title：Frontiers in pediatrics

authors： Okulu E,Erdeve O,Pekcici BB,Kendirli T,Eyileten Z,Atasay B,Arsan S

更新日期：2019-03-22 00:00:00

abstract：:Asthma is the most common chronic disease in children, imposing a consistent burden on health system. In recent years, prevalence of asthma symptoms became globally increased in children and adolescents, particularly in Low-Middle Income Countries (LMICs). Host (genetics, atopy) and environmental factors (microbial ex...

journal_title：Frontiers in pediatrics

authors： Ferrante G,La Grutta S

更新日期：2018-06-22 00:00:00

abstract：:Objective: Lactate is often used as a surrogate marker of inappropriate oxygen delivery. It has been shown that hyperlactatemia is associated with worse clinical outcome in children after cardiac surgery. The purpose of this study is to evaluate the association of hyperlactatemia, low systemic oxygen delivery, and hyp...

journal_title：Frontiers in pediatrics

authors： Klee P,Rimensberger PC,Karam O

更新日期：2020-06-23 00:00:00

abstract：:The concept of orthostatic hypertension in children was first proposed in 2012. The pathogenesis is not clear by now. Orthostatic hypertension is one of the important causes of orthostatic intolerance in children and is related to the development of essential hypertension in the future. It is commonly seen in older ch...

journal_title：Frontiers in pediatrics

authors： Hu Y,Jin H,Du J

更新日期：2020-07-29 00:00:00

abstract：:Introduction: Ventilation causes cerebral white matter inflammation and injury, which is exacerbated by intrauterine inflammation. However, the effects on cortical gray matter are not well-known. Our aim was to examine the effect of ventilation on the cerebral cortex of near-term lambs exposed to intrauterine inflamma...

journal_title：Frontiers in pediatrics

authors： Stojanovska V,Atik A,Nitsos I,Skiöld B,Barton SK,Zahra VA,Rodgers K,Hooper SB,Polglase GR,Galinsky R

更新日期：2018-06-15 00:00:00

abstract：:Non-cystic fibrosis bronchiectasis (NCFB) has gained renewed interest, due to its increasing health-care burden. Annual mortality statistics in England and Wales showed that under 1,000 people die from bronchiectasis each year, and this number is increasing by 3% yearly. Unfortunately, there is a severe lack of well-p...

journal_title：Frontiers in pediatrics

authors： Nathan AM,de Bruyne JA,Eg KP,Thavagnanam S

更新日期：2017-04-24 00:00:00

abstract：:Introduction: Surfactant proteins (SP) have been shown to be inherent proteins of the human CNS and are altered during acute and chronic disturbances of CSF circulation. Aim of the study was to examine the changes of surfactant protein concentrations in CSF of preterm babies suffering from intraventricular hemorrhage....

journal_title：Frontiers in pediatrics

authors： Krause M,Härtig W,Mahr CV,Richter C,Schob J,Puchta J,Hoffmann KT,Nestler U,Thome U,Knüpfer M,Gebauer C,Schob S

更新日期：2020-09-25 00:00:00

abstract：:Objective: Magnetic resonance imaging (MRI) and cardiac catheterization are diagnostic tools for right ventricle dysfunction (RVD), but those are expensive and often unavailable techniques. Thus, our objective was to identify clinical and/or echocardiographic variables capable of predicting a catheterization-based dia...

journal_title：Frontiers in pediatrics

authors： Márquez-González H,Vargas MH,Yáñez-Gutiérrez L,Almeida-Gutiérrez E,Garduño-Espinosa J

更新日期：2018-06-26 00:00:00

abstract：:The evaluation and treatment of the heterogeneous group of kidney diseases poses a challenging field in pediatrics. Many of the pediatric disorders resulting in severe renal affection are exceedingly rare and therapeutic approaches have remained symptomatic for most of these disease entities. The insights obtained fro...

journal_title：Frontiers in pediatrics

authors： Liebau MC

更新日期：2014-07-01 00:00:00

abstract：:We constructed an optimal machine learning (ML) method for predicting intravenous immunoglobulin (IVIG) resistance in children with Kawasaki disease (KD) using commonly available clinical and laboratory variables. We retrospectively collected 98 clinical records of hospitalized children with KD (2-109 months of age). ...

journal_title：Frontiers in pediatrics

authors： Kuniyoshi Y,Tokutake H,Takahashi N,Kamura A,Yasuda S,Tashiro M

更新日期：2020-12-03 00:00:00

abstract：UNLABELLED:Pediatric acute encephalopathy (AE) was sometimes attributed to virus infection. However, viral infection does not always result in AE. The risk factors for developing infantile AE upon virus infection remain to be determined. Here, we report an infant with AE co-infected with human herpesvirus-6 (HHV-6) and...

journal_title：Frontiers in pediatrics

authors： Nakata K,Kashiwagi M,Masuda M,Shigehara S,Oba C,Murata S,Kase T,Komano JA

更新日期：2015-04-02 00:00:00

abstract：:Despite distinct epidemiology and outcomes, pediatric acute respiratory distress syndrome (PARDS) is often managed based on evidence extrapolated from treatment of adults. The impact of non-pulmonary processes on mortality as well as the lower mortality rate compared to adults with acute respiratory distress syndrome ...

journal_title：Frontiers in pediatrics

authors： Yehya N,Thomas NJ

更新日期：2016-05-13 00:00:00

abstract：:The current study investigated the differences between intact and non-intact families in family processes, including systematic family functioning, parental behavioral control, parental psychological control, and parent-child relational qualities. The participants were 3,328 Secondary One students, with a mean age of ...

journal_title：Frontiers in pediatrics

authors： Shek DT,Xie Q,Lin L

更新日期：2015-01-29 00:00:00

abstract：:We describe a giant gastric phytobezoar in a child with repaired congenital esophageal atresia. At age two, a gastric interposition (pull-up) procedure was performed for severe and recurrent esophageal strictures. For 12 months post-gastric interposition, he experienced frequent respiratory illnesses requiring hospita...

journal_title：Frontiers in pediatrics

authors： Chacko A,Masters BI,Isles A

更新日期：2017-06-19 00:00:00

abstract：OBJECTIVES:To determine the influence of family, peers, school, and physicians on exercise in pediatric oncology patients and evaluate the barriers to physical activity (PA) levels in this population. METHODS:A search of PubMed and Google Scholar resulted in 12 related articles. The articles were assessed for the infl...

journal_title：Frontiers in pediatrics

authors： Yelton L,Forbis S

更新日期：2016-12-19 00:00:00

abstract：:Background: Histological chorioamnionitis (HCA) is an infection/inflammation of fetal membranes and complicates 5.2-28.5% of all live births. Exposure to HCA can have long-term consequences including abnormal neurodevelopment and an increased risk for allergic disorders and asthma later in childhood. HCA may incite ep...

journal_title：Frontiers in pediatrics

authors： Fong G,Gayen Nee' Betal S,Murthy S,Favara M,Chan JSY,Addya S,Shaffer TH,Greenspan J,Bhandari V,Li D,Rahman I,Aghai ZH

更新日期：2020-08-04 00:00:00

abstract：:Introduction: Mutations in the contactin-associated protein-like 2 (CNTNAP2) gene (MIM#604569) encoding for CASPR2, a cell adhesion protein of the neurexin family, are known to be associated with autism, intellectual disability, and other neuropsychiatric disorders. A set of intronic deletions of CNTNAP2 gene has also...

journal_title：Frontiers in pediatrics

authors： Falsaperla R,Pappalardo XG,Romano C,Marino SD,Corsello G,Ruggieri M,Parano E,Pavone P

更新日期：2020-09-11 00:00:00

abstract：:High-pressure processing (HPP) is a non-thermal technology that is being increasingly applied in food industries worldwide. It was proposed that this method could be used as an alternative to holder pasteurization (HoP; 62.5°C, 30 min) in milk banks but its impact on the immunologic, enzymatic and hormonal components ...

journal_title：Frontiers in pediatrics

authors： Wesolowska A,Sinkiewicz-Darol E,Barbarska O,Strom K,Rutkowska M,Karzel K,Rosiak E,Oledzka G,Orczyk-Pawiłowicz M,Rzoska S,Borszewska-Kornacka MK

更新日期：2018-11-16 00:00:00

abstract：:To date, the only known effective treatment for celiac disease (CD) is a strict gluten-free diet (GFD) for life. Patients with CD often find it difficult to adhere to strict GFD. Oats, compared with wheat, barley, and rye, contain less amounts of prolamins. Inclusion of oats in a GFD might be valuable due to their nut...

journal_title：Frontiers in pediatrics

authors： Spector Cohen I,Day AS,Shaoul R

更新日期：2019-09-26 00:00:00

abstract：:Perianal abscess and fistula-in-ano are well-described in the pediatric population. They are most common in infants less than 1 year of age and often resolve with oral antibiotics; occasionally they require drainage or fistulotomy. The etiology is commonly associated with cryptoglandular obstruction and subsequent inf...

journal_title：Frontiers in pediatrics

authors： Barry WE,Asuelime GE,Zhou S,Hammoudeh J,Ford HR,Kim ES

更新日期：2018-05-16 00:00:00

abstract：:Objective: To present 8-year follow-up outcomes, treatment of complications, and prognosis in children with congenital tracheal stenosis after metallic airway stent implantation. Methods: Retrospective analysis was performed on the clinical records of children who had airway stents placed between May 20, 2011 and May ...

journal_title：Frontiers in pediatrics

authors： Wang M,Zhu B,Xu X

更新日期：2020-10-26 00:00:00

abstract：:We report a novel homozygous JAK3 mutation in two female Brazilian SCID infants from two unrelated kindreds. Patient 1 was referred at 2 months of age due to a family history of immunodeficiency and the appearance of a facial rash. The infant was screened for TRECs (T-cell receptor excision circles) and KRECs (kappa-d...

journal_title：Frontiers in pediatrics

authors： Barreiros LA,Segundo GRS,Grumach AS,Roxo-Júnior P,Torgerson TR,Ochs HD,Condino-Neto A

更新日期：2018-08-20 00:00:00

abstract：:Objectives: Mutations in the neuroblastoma-amplified sequence (NBAS) gene were originally described in patients with skeletal dysplasia or isolated liver disease of variable severity. Subsequent publications reported a more complex phenotype. Among multisystemic clinical symptoms, we were particularly interested in th...

journal_title：Frontiers in pediatrics

authors： Khoreva A,Pomerantseva E,Belova N,Povolotskaya I,Konovalov F,Kaimonov V,Gavrina A,Zimin S,Pershin D,Davydova N,Burlakov V,Viktorova E,Roppelt A,Kalinina E,Novichkova G,Shcherbina A

更新日期：2020-09-15 00:00:00

abstract：:Background: Cystinuria is an inborn error of metabolism that manifests with renal stones due to defective renal epithelial cell transport of cystine which resulted from pathogenic variants in the SLC3A1 and/or SLC7A9 genes. Among nephrolithiasis diseases, cystinuria is potentially treatable, and further stone formatio...

journal_title：Frontiers in pediatrics

authors： Alghamdi M,Alhasan KA,Taha Elawad A,Salim S,Abdelhakim M,Nashabat M,Raina R,Kari J,Alfadhel M

更新日期：2020-11-11 00:00:00

abstract：:Sensory processing difficulties are common among many special needs children, especially those with autism spectrum disorder (ASD). The sensory sensitivities often result in interference of daily functioning and can lead to social isolation for both the individual and family unit. A quality improvement (QI) project wa...

journal_title：Frontiers in pediatrics

authors： Kong M,Pritchard M,Dean L,Talley M,Torbert R,Maha J

更新日期：2017-09-15 00:00:00

abstract：:Introduction: Anterior lens capsule vascularity (ALCV) is resorbed in the developing fetus from 27 to 35 weeks gestation. In this pilot study, we evaluated the feasibility and validity of combining smartphone ophthalmoscope videos of ALCV and image analysis for gestational age estimation. Methods: ALCV videos were cap...

journal_title：Frontiers in pediatrics

authors： Patel M,Mukherjee D,Farsiu S,Munoz B,Blood AB,Wilson CG,Griffin JB

更新日期：2019-02-20 00:00:00

abstract：:Lung function is an important tool in the diagnosis and monitoring of patients with asthma at all ages. Airway obstruction is a typical feature of asthma and it can be assessed with several lung function techniques. Spirometry, respiratory resistance and reactance, and lung volumes are available to measure it at diffe...

journal_title：Frontiers in pediatrics

authors： Calogero C,Fenu G,Lombardi E

更新日期：2018-06-26 00:00:00