Estimation of Gestational Age via Image Analysis of Anterior Lens Capsule Vascularity in Preterm Infants: A Pilot Study.

Abstract:

:Introduction: Anterior lens capsule vascularity (ALCV) is resorbed in the developing fetus from 27 to 35 weeks gestation. In this pilot study, we evaluated the feasibility and validity of combining smartphone ophthalmoscope videos of ALCV and image analysis for gestational age estimation. Methods: ALCV videos were captured longitudinally in preterm neonates from delivery using a PanOptic® Ophthalmoscope with an iExaminer® adapter (Welch-Allyn). ALCV video frames were manually selected and quantified using semi-automatic image analysis. A predictive model based on ALCV features was compared to gold-standard ultrasound gestational age estimates. Results: A total of 64 image-capture sessions were carried out in 24 neonates. Ultrasound-estimated gestational age and ALCV-predicted gestational age estimates indicate that the two methods are similar (r = 0.78, p < 0.0001). ALCV estimates of gestational age were within 0.11 ± 1.3 weeks of ultrasound estimates. In the final model, gestational age was predicted within ± 1 week for 54% and within ± 2 weeks for 86% of the measures. Conclusions: This novel application of smartphone ophthalmoscopy and ALCV image analysis may provide a safe, accurate and non-invasive technology to estimate postnatal gestational age, especially in low income countries where gestational age may not be known at birth.

journal_name

Front Pediatr

journal_title

Frontiers in pediatrics

authors

Patel M,Mukherjee D,Farsiu S,Munoz B,Blood AB,Wilson CG,Griffin JB

doi

10.3389/fped.2019.00043

subject

Has Abstract

pub_date

2019-02-20 00:00:00

pages

43

issn

2296-2360

journal_volume

7

pub_type

杂志文章
  • New Therapeutics Options for Pediatric Neuromuscular Disorders.

    abstract::Neuromuscular disorders (NMDs) of Childhood onset are a genetically heterogeneous group of diseases affecting the anterior horn cell, the peripheral nerve, the neuromuscular junction, or the muscle. For many decades, treatment of NMDs has been exclusively symptomatic. But this has changed fundamentally in recent years...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章,评审

    doi:10.3389/fped.2020.583877

    authors: Flotats-Bastardas M,Hahn A

    更新日期:2020-11-23 00:00:00

  • Interhospital Transport on Extracorporeal Membrane Oxygenation of Neonates-Perspective for the Future.

    abstract::In recent years the number of extracorporeal membrane oxygenation (ECMO) cases in neonates has been relatively constant. Future expansion lays in new indications for treatment. Regionalization to high-volume ECMO centers allows for optimal utilization of resources, reduction in costs, morbidity, and mortality. Mobile ...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2019.00329

    authors: Broman LM

    更新日期:2019-08-06 00:00:00

  • Severe Adenovirus Pneumonia Requiring Extracorporeal Membrane Oxygenation Support in Immunocompetent Children.

    abstract::Objective: To highlight severe adenovirus pneumonia in immunocompetent patients by analysis of severe adenovirus pneumonia associated with acute respiratory distress syndrome in whom extracorporeal membrane oxygenation (ECMO) support is required. Methods:Pediatric patients with adenovirus pneumonia and ECMO supports i...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2020.00162

    authors: Chen X,Lv J,Qin L,Zou C,Tang L

    更新日期:2020-04-15 00:00:00

  • Hypercalcemia, an Important Puzzle Piece in Uncommon Onset Pediatric Sarcoidosis-A Case Report and a Review of the Literature.

    abstract::Sarcoidosis (SD) is a systemic granulomatous condition that is especially encountered in young adults and rarely in children, affecting predominantly the lungs and lymph nodes. We report the case of a 14-year-old teenage boy admitted to our clinic for nausea, vomiting, and weight loss. Clinical examination at the time...

    journal_title:Frontiers in pediatrics

    pub_type:

    doi:10.3389/fped.2020.00497

    authors: Mărginean CO,Meliţ LE,Grigorescu G,Puiac C,Simu I

    更新日期:2020-08-26 00:00:00

  • Vasculitis in a Child With the Hyper-IgM Variant of Ataxia-Telangiectasia.

    abstract::A subset of patients with Ataxia-Telangiectasia (A-T) have dramatically reduced levels of IgG, IgA, and IgE with retained or elevated IgM levels. Several reports suggest that these A-T patients with a "hyper-IgM phenotype" (HIgM) suffer more clinical immunologic consequences than other A-T patients. The immunopatholog...

    journal_title:Frontiers in pediatrics

    pub_type:

    doi:10.3389/fped.2019.00390

    authors: Meyer AK,Banks M,Nadasdy T,Clark JJ,Zheng R,Gelfand EW,Abbott JK

    更新日期:2019-10-24 00:00:00

  • A child with acute encephalopathy associated with quadruple viral infection.

    abstract:UNLABELLED:Pediatric acute encephalopathy (AE) was sometimes attributed to virus infection. However, viral infection does not always result in AE. The risk factors for developing infantile AE upon virus infection remain to be determined. Here, we report an infant with AE co-infected with human herpesvirus-6 (HHV-6) and...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2015.00026

    authors: Nakata K,Kashiwagi M,Masuda M,Shigehara S,Oba C,Murata S,Kase T,Komano JA

    更新日期:2015-04-02 00:00:00

  • Cardiac and Inflammatory Necrotizing Enterocolitis in Newborns Are Not the Same Entity.

    abstract::Background: Necrotizing enterocolitis (NEC) is an often-fatal neonatal disease involving intestinal hyperinflammation leading to necrosis. Despite ongoing research, (1) conflicting results and (2) comorbidities of NEC patients make early NEC detection challenging and may complicate therapy development. Most research s...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2020.593926

    authors: Klinke M,Wiskemann H,Bay B,Schäfer HJ,Pagerols Raluy L,Reinshagen K,Vincent D,Boettcher M

    更新日期:2021-01-06 00:00:00

  • Risk Factors for Recurrent Intussusception in Children: A Systematic Review and Meta-Analysis.

    abstract::Background: Intussusception is a common abdominal emergency in infancy and childhood, and the recurrence rate is reported to be up to 20%. Numerous potential risk factors for recurrence have been reported, although some of them are still controversial. Objective: The present study was conducted to identify the risk fa...

    journal_title:Frontiers in pediatrics

    pub_type:

    doi:10.3389/fped.2019.00145

    authors: Ye X,Tang R,Chen S,Lin Z,Zhu J

    更新日期:2019-04-16 00:00:00

  • Interest of URS-L in the Treatment of Ureterolithiasis in Preschool Children.

    abstract::Urolithiasis can affect all children even preschool ones. Diagnostic difficulties in the youngest children are due to the problems in locating pain and determining its character and severity. In keeping with the ALARA (As Low As Reasonably Achievable) protocol, the number of imaging tests possible to perform is very l...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2019.00324

    authors: Halinski A,Halinski A,Zaniew M,Kudliński B,Soltysiak J,Sobolewski B,Steyaert H

    更新日期:2019-09-06 00:00:00

  • Rediscovering Pertussis.

    abstract::Pertussis, caused by Bordetella (B.) pertussis, a Gram-negative bacterium, is a highly contagious airway infection. Especially in infants, pertussis remains a major health concern. Acute infection with B. pertussis can cause severe illness characterized by severe respiratory failure, pulmonary hypertension, leucocytos...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章,评审

    doi:10.3389/fped.2016.00052

    authors: Zlamy M

    更新日期:2016-06-08 00:00:00

  • Relationship Between Oxidative Stress Markers and Endothelin-1 Levels in Newborns of Different Gestational Ages.

    abstract::Oxidative stress results from excessive reactive oxygen species formation and/or inadequate antioxidant defense. Premature and critically ill infants are especially susceptible due to an immature intrinsic antioxidant system that cannot fully compensate for a free radical load. Oxidative stress is also associated with...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2020.00279

    authors: Stefanov G,Briyal S,Pais G,Puppala B,Gulati A

    更新日期:2020-06-02 00:00:00

  • Corrigendum: A Novel Homozygous JAK3 Mutation Leading to T-B+NK- SCID in Two Brazilian Patients.

    abstract::[This corrects the article DOI: 10.3389/fped.2018.00230.]. ...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章,已发布勘误

    doi:10.3389/fped.2018.00358

    authors: Barreiros LA,Segundo GRS,Grumach AS,Roxo-Júnior P,Torgerson TR,Ochs HD,Condino-Neto A

    更新日期:2018-11-23 00:00:00

  • How Salty Are Your Fluids? Pediatric Maintenance IV Fluid Prescribing Practices Among Hospitalists.

    abstract::Objective: The primary goal of this study was to assess current maintenance intravenous fluid (mIVF) prescribing practices of pediatric hospitalists after the release of the American Academy of Pediatrics Clinical Practice Guideline (AAP CPG), specifically assessing the rates of various isotonic vs. hypotonic solution...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2019.00549

    authors: Hall AM,Ayus JC,Moritz ML

    更新日期:2020-01-15 00:00:00

  • Segmental Colitis Associated Diverticulosis-A Possible Diagnosis in Teenagers.

    abstract::Segmental colitis associated with diverticulosis (SCAD) is manifested by active chronic inflammation of the colonic segments affected by diverticulosis, luminal-mucosal inflammation, independent of the presence of inflammation within and/or around the diverticula, and it usually spares the rectum. We present the case ...

    journal_title:Frontiers in pediatrics

    pub_type:

    doi:10.3389/fped.2018.00168

    authors: Mǎrginean CO,Meliţ LE,Mǎrginean MO

    更新日期:2018-06-05 00:00:00

  • New Drugs for Pediatric Asthma.

    abstract::Asthma is the most common chronic disease in children. As suggested by international guidelines, the main goals of asthma treatment are symptoms control and lung function preservation, through a stepwise and control-based approach. The first line therapy based on inhaled corticosteroids may fail to reach control in mo...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章,评审

    doi:10.3389/fped.2018.00432

    authors: Maglione M,Poeta M,Santamaria F

    更新日期:2019-01-16 00:00:00

  • Use of High-Dose Chemotherapy in Front-Line Therapy of Infants Aged Less Than 12 Months Treated for Aggressive Brain Tumors.

    abstract::Introduction: Malignant brain tumors in infants less than 12 months of age are extremely rare, and they have poor prognosis. We evaluated genetic characteristics and response rates of infants with congenital brain tumors subjected to high-dose chemotherapy and autologous stem cell transplant after gross total tumor re...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2020.00135

    authors: Guidi M,Giunti L,Buccoliero AM,Santi M,Spacca B,De Masi S,Genitori L,Sardi I

    更新日期:2020-04-09 00:00:00

  • Routine Pediatric Vaccination in Pakistan During COVID-19: How Can Healthcare Professionals Help?

    abstract::Pakistan is still fighting to overcome vaccine-preventable diseases (VPD). The vaccination coverage in rural children remains unsatisfactory amid various barriers including price, hesitancy, and low level of awareness. COVID-19 has decreased the immunization rate in Pakistan due to restricted movements, shortage of va...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2020.613433

    authors: Khan A,Bibi A,Sheraz Khan K,Raza Butt A,Alvi HA,Zahra Naqvi A,Mushtaq S,Khan YH,Ahmad N

    更新日期:2020-12-10 00:00:00

  • The Relationship Between Pediatric Residents' Experiences Being Parented and Their Provision of Parenting Advice.

    abstract::Background: Factors surrounding pediatricians' parenting advice and training on parenting during residency have not been well studied. The Resident Parenting Questionnaire (RPQ) was developed to assess (a) the relationship between pediatric residents' upbringing and their parenting advice style and (b) factors associa...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2018.00395

    authors: Bax AC,Shawler PM,Anderson MP,Wolraich ML

    更新日期:2018-12-12 00:00:00

  • Predictors of Sleep Duration and Sleep Disturbance in Children of a Culturally Diverse Region in North-Eastern Greece.

    abstract::Background Aim: The aim of this study was to examine the sleep characteristics of children and explore associations with various socio-demographic factors in an area of Greece characterized by cultural diversity. Methods: A questionnaire about children's sleep habits had been distributed to parents of children who vis...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2020.00023

    authors: Nena E,Cassimos D,Kaditis A,Kourantzi M,Trakada G,Economou NT,Nikolaidis PT,Rosemann T,Knechtle B,Steiropoulos P,Tsalkidis A

    更新日期:2020-02-12 00:00:00

  • Chronic Thromboembolic Pulmonary Hypertension in a Child With Sickle Cell Disease.

    abstract::Chronic thromboembolic pulmonary hypertension is a potentially curable form of pre-capillary pulmonary hypertension (PH) resulting from incomplete resolution of pulmonary thromboemboli. We describe an 11-year-old boy with homozygous sickle cell disease with an indwelling catheter found to have severe PH on routine scr...

    journal_title:Frontiers in pediatrics

    pub_type:

    doi:10.3389/fped.2020.00363

    authors: Spencer R,Valencia Villeda G,Takeda K,Rosenzweig EB

    更新日期:2020-07-24 00:00:00

  • Corrigendum: Subcutaneous and Sublingual Immunotherapy in Allergic Asthma in Children.

    abstract::[This corrects the article on p. 82 in vol. 5, PMID: 28484690.]. ...

    journal_title:Frontiers in pediatrics

    pub_type: 已发布勘误

    doi:10.3389/fped.2017.00187

    authors: Tsabouri S,Mavroudi A,Feketea G,Guibas GV

    更新日期:2017-09-11 00:00:00

  • Sex Differences in Brain Injury and Repair in Newborn Infants: Clinical Evidence and Biological Mechanisms.

    abstract::Differences in the development of the male and female brain are an evolving area of investigation. We are beginning to understand the underpinnings of male and female advantages due to differences in brain development as well as the consequences following hypoxic-ischemic brain injury in the newborn. The two main fact...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章,评审

    doi:10.3389/fped.2019.00211

    authors: Rosenkrantz TS,Hussain Z,Fitch RH

    更新日期:2019-06-26 00:00:00

  • An emerging molecular understanding and novel targeted treatment approaches in pediatric kidney diseases.

    abstract::The evaluation and treatment of the heterogeneous group of kidney diseases poses a challenging field in pediatrics. Many of the pediatric disorders resulting in severe renal affection are exceedingly rare and therapeutic approaches have remained symptomatic for most of these disease entities. The insights obtained fro...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章,评审

    doi:10.3389/fped.2014.00068

    authors: Liebau MC

    更新日期:2014-07-01 00:00:00

  • Association of Picky Eating with Growth, Nutritional Status, Development, Physical Activity, and Health in Preschool Children.

    abstract:Background:This study aimed to assess the prevalence of picky eating among preschool children and to evaluate the association between eating behavior and growth, physical activity, development, and health status. Methods:A structured questionnaire was used to conduct a cross-sectional descriptive study of 300 primary ...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2018.00022

    authors: Chao HC

    更新日期:2018-02-12 00:00:00

  • Predicting Asthma Using Clinical Indexes.

    abstract::Asthma is no longer considered a single disease, but a common label for a set of heterogeneous conditions with shared clinical symptoms but associated with different cellular and molecular mechanisms. Several wheezing phenotypes coexist at preschool age but not all preschoolers with recurrent wheezing develop asthma a...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章,评审

    doi:10.3389/fped.2019.00320

    authors: Castro-Rodriguez JA,Cifuentes L,Martinez FD

    更新日期:2019-07-31 00:00:00

  • The challenges facing training in pediatric surgery worldwide.

    abstract::Like most specialties, pediatric surgery is becoming more complex, and changes to health systems have not always been in the best interests of trainees or their surgical teachers. This paper outlines four of the current challenges faced by training boards in pediatric surgery worldwide, and documents their implication...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章,评审

    doi:10.3389/fped.2013.00024

    authors: Beasley SW

    更新日期:2013-09-11 00:00:00

  • Effects of Probiotic Supplementation on the Gut Microbiota and Antibiotic Resistome Development in Preterm Infants.

    abstract::Objectives: In 2014 probiotic supplementation (Lactobacillus acidophilus and Bifidobacterium longum subspecies infantis; InfloranⓇ) was introduced as standard of care to prevent necrotizing enterocolitis (NEC) in extremely preterm infants in Norway. We aimed to evaluate the influence of probiotics and antibiotic thera...

    journal_title:Frontiers in pediatrics

    pub_type:

    doi:10.3389/fped.2018.00347

    authors: Esaiassen E,Hjerde E,Cavanagh JP,Pedersen T,Andresen JH,Rettedal SI,Støen R,Nakstad B,Willassen NP,Klingenberg C

    更新日期:2018-11-16 00:00:00

  • Respiratory Muscle Strength and Exercise Performance in Cystic Fibrosis-A Cross Sectional Study.

    abstract::Introduction: Decreased respiratory muscle strength in patients with cystic fibrosis (CF) may cause progressive exercise intolerance during cardiopulmonary exercise testing (CPET), and may contribute to the development of chronic respiratory insufficiency. The aim of this study is to evaluate exercise tolerance during...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2018.00244

    authors: Sovtic A,Minic P,Markovic-Sovtic G,Trajkovic GZ

    更新日期:2018-09-04 00:00:00

  • Prevalence of Respiratory Polyomaviruses Among Pediatric Patients With Respiratory Symptoms in Singapore.

    abstract::Background: Although WU polyomavirus (WU) and KI polyomavirus (KI) have been demonstrated to infect the human respiratory tract, it remains unclear if WU or KI cause human disease. We sought to further investigate the relationship between WU and KI infection and respiratory disease in a pediatric population with respi...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2018.00228

    authors: Hansen-Estruch C,Coleman KK,Thoon KC,Low JG,Anderson BD,Gray GC

    更新日期:2018-08-17 00:00:00

  • Reflective Practice About Retroperitoneal Laparoscopy in Comparison to Open Surgery for Ureteropelvic Junction Obstruction Repair in Children Less Than 1 Year of Age.

    abstract::Introduction: The interest in laparoscopy in the treatment of ureteropelvic junction obstruction (UPJO) in children under 12 months of age remains controversial. The aim of this study is to evaluate feasibility and benefits of retroperitoneal laparoscopy (RL) compared to open surgery in this age group. Materials and M...

    journal_title:Frontiers in pediatrics

    pub_type: 杂志文章

    doi:10.3389/fped.2019.00194

    authors: Kallas-Chemaly A,Peycelon M,Ali L,Grapin-Dagorno C,Carricaburu E,Philippe-Chomette P,Enezian G,Paye-Jaouen A,El-Ghoneimi A

    更新日期:2019-05-24 00:00:00