The challenges facing training in pediatric surgery worldwide.

abstract：:Objective: To evaluate serial ferritin levels measured in the initial 72 h of admission as a biomarker for new and progressive multi organ dysfunction syndrome (NPMODS) and mortality (unfavorable outcomes) in critically ill children with sepsis due to tropical infections. Material and Methods: In this prospective obse...

journal_title：Frontiers in pediatrics

authors： Williams V,Menon N,Bhatia P,Biswal M,Sreedharanunni S,Rawat A,Jayashree M,Nallasamy K

更新日期：2020-12-03 00:00:00

abstract：:Background: Eye exam for Retinopathy of prematurity (ROP) is a painful procedure and pharmacological analgesia might be ineffective. We hypothesized that magnetic auricular acupuncture (MAA) compared to placebo will decrease pain during ROP exam in preterm infants. Methods: Multicentre randomized controlled trial cond...

journal_title：Frontiers in pediatrics

authors： Gan KML,Oei JL,Quah-Smith I,Kamar AA,Lordudass AAD,Liem KD,Lindrea KB,Daly M,Gaunker N,Mangat AK,Yaskina M,Schmölzer GM

更新日期：2020-12-23 00:00:00

abstract：:Objective: To present 8-year follow-up outcomes, treatment of complications, and prognosis in children with congenital tracheal stenosis after metallic airway stent implantation. Methods: Retrospective analysis was performed on the clinical records of children who had airway stents placed between May 20, 2011 and May ...

journal_title：Frontiers in pediatrics

authors： Wang M,Zhu B,Xu X

更新日期：2020-10-26 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a chronic, immune-mediated, non-curable disease. The incidence of IBD appears to have risen over the last few decades especially in the pediatric age group. IBD usually presents with gastrointestinal symptoms, including abdominal pain, diarrhea, and bleeding per rectum but can also ...

journal_title：Frontiers in pediatrics

authors： El-Matary W,Bernstein CN

更新日期：2020-07-17 00:00:00

abstract：:Neuromuscular disorders (NMDs) of Childhood onset are a genetically heterogeneous group of diseases affecting the anterior horn cell, the peripheral nerve, the neuromuscular junction, or the muscle. For many decades, treatment of NMDs has been exclusively symptomatic. But this has changed fundamentally in recent years...

journal_title：Frontiers in pediatrics

authors： Flotats-Bastardas M,Hahn A

更新日期：2020-11-23 00:00:00

abstract：:Background: High parent education is protective against youth health risk behaviors such as tobacco use. According to the Minorities' Diminished Returns theory, however, higher parent education seems to exert less protection for the ethnic minority relative to the majority groups. Objectives: To explore ethnic differe...

journal_title：Frontiers in pediatrics

authors： Assari S,Boyce S,Caldwell CH,Bazargan M

更新日期：2020-08-19 00:00:00

abstract：:Excessive oxygen (O2) can cause tissue injury, scarring, aging, and even death. Our laboratory is studying O2-sensing pulmonary neuroendocrine cells (PNECs) and the PNEC-derived product gastrin-releasing peptide (GRP). Reactive oxygen species (ROS) generated from exposure to hyperoxia, ozone, or ionizing radiation (RT...

journal_title：Frontiers in pediatrics

authors： Sunday ME

更新日期：2014-07-18 00:00:00

abstract：:Perianal abscess and fistula-in-ano are well-described in the pediatric population. They are most common in infants less than 1 year of age and often resolve with oral antibiotics; occasionally they require drainage or fistulotomy. The etiology is commonly associated with cryptoglandular obstruction and subsequent inf...

journal_title：Frontiers in pediatrics

authors： Barry WE,Asuelime GE,Zhou S,Hammoudeh J,Ford HR,Kim ES

更新日期：2018-05-16 00:00:00

abstract：:Fetal sex is associated with striking differences during in utero development, fetal-to-neonatal transition, and postnatal morbidity and mortality. Male sex fetuses are apparently protected while in utero resulting in a higher secondary sex rate for males than for females. However, during fetal-to-neonatal transition ...

journal_title：Frontiers in pediatrics

authors： Lorente-Pozo S,Parra-Llorca A,Torres B,Torres-Cuevas I,Nuñez-Ramiro A,Cernada M,García-Robles A,Vento M

更新日期：2018-04-23 00:00:00

abstract：:Childhood asthma is actually defined as a heterogeneous disease, including different clinical variants and partially sharing similar immune mechanisms. Asthma management is mainly focused on maintaining the control of the disease and reducing the risk of adverse outcomes. Most children achieve good control with standa...

journal_title：Frontiers in pediatrics

authors： Licari A,Manti S,Castagnoli R,Marseglia A,Foiadelli T,Brambilla I,Marseglia GL

更新日期：2019-07-12 00:00:00

abstract：:Background: Percutaneous balloon valvuloplasty (PBPV) is recommended as a first-choice treatment for critical pulmonary stenosis (CPS). A concept of perinatal integrative management has been developed. Unfortunately, the evidence on the advantage of integrative management for CPS during the perinatal period is absent....

journal_title：Frontiers in pediatrics

authors： Li J,Li G,Shi X,Wang C,Duan H,Zhou K,Hua Y,Li Y

更新日期：2020-12-21 00:00:00

abstract：:Severe invasive infections such as brain abscess in a child should prompt an immune evaluation. Specific granule deficiency (SGD) is a rare morphologic neutrophil granular defect characterized by reduced granules within neutrophils, absence of granule proteins, and bilobed nuclei. Patients are susceptible to invasive ...

journal_title：Frontiers in pediatrics

authors： Leszcynska M,Patel B,Morrow M,Chamizo W,Tuite G,Berman DM,Potthast K,Hsu AP,Holland SM,Leiding JW

更新日期：2020-04-22 00:00:00

abstract：:Introduction: Decreased respiratory muscle strength in patients with cystic fibrosis (CF) may cause progressive exercise intolerance during cardiopulmonary exercise testing (CPET), and may contribute to the development of chronic respiratory insufficiency. The aim of this study is to evaluate exercise tolerance during...

journal_title：Frontiers in pediatrics

authors： Sovtic A,Minic P,Markovic-Sovtic G,Trajkovic GZ

更新日期：2018-09-04 00:00:00

abstract：OBJECTIVE:This study aimed to evaluate circulating natriuretic peptides (NP) concentration in obese and non-obese children and adolescents with and without obstructive sleep apnea (OSA), and their levels following OSA treatment. METHODS:Subjects with habitual snoring and symptoms suggestive of OSA were recruited. They...

journal_title：Frontiers in pediatrics

authors： Li AM,Au CT,Zhu JY,Chan KC,Chan MH,Lee DL,Wing YK

更新日期：2014-03-24 00:00:00

abstract：:Introduction: Ventilation causes cerebral white matter inflammation and injury, which is exacerbated by intrauterine inflammation. However, the effects on cortical gray matter are not well-known. Our aim was to examine the effect of ventilation on the cerebral cortex of near-term lambs exposed to intrauterine inflamma...

journal_title：Frontiers in pediatrics

authors： Stojanovska V,Atik A,Nitsos I,Skiöld B,Barton SK,Zahra VA,Rodgers K,Hooper SB,Polglase GR,Galinsky R

更新日期：2018-06-15 00:00:00

abstract：:Deficiency of adenosine deaminase 2 (DADA2) is a monogenic form of systemic vasculopathy that often presents during early childhood. Linked to biallelic mutations in ADA2 (previously CECR1), DADA2 was initially described as a syndrome of recurrent fever, livedo racemosa, early-onset strokes, and peripheral vasculopath...

journal_title：Frontiers in pediatrics

authors： Lee PY

更新日期：2018-10-18 00:00:00

abstract：:Background: Despite the pandemic, data are limited regarding COVID-19 infection in pregnant women and newborns. This report aimed to bring new information about presentation that could modify precautionary measures for infants born of mothers with a remote history of COVID-19. Methods: We report two infants with possi...

journal_title：Frontiers in pediatrics

authors： Hascoët JM,Jellimann JM,Hartard C,Wittwer A,Jeulin H,Franck P,Morel O

更新日期：2020-09-29 00:00:00

abstract：:Cystic kidney diseases comprise a varied collection of hereditary disorders, where renal cysts comprise a major element of their pleiotropic phenotype. In pediatric patients, the term polycystic kidney disease (PKD) commonly refers to two specific hereditary diseases, autosomal recessive polycystic kidney disease (ARP...

journal_title：Frontiers in pediatrics

authors： Sweeney WE Jr,Avner ED

更新日期：2017-04-19 00:00:00

abstract：:Over the past decade, there has been a growing awareness of the vital role of the microbiome in the function of the immune system. Recently, several studies have demonstrated a relationship between the composition of the microbiome and the vaccine-specific immune response. As a result of these findings, the administra...

journal_title：Frontiers in pediatrics

authors： Ruck CE,Odumade OA,Smolen KK

更新日期：2020-11-26 00:00:00

abstract：:Introduction: Hemolytic-uremic syndrome (HUS) is a common cause for intrarenal acute kidney injury in childhood. More than 90% of HUS cases are associated with an infection by Shigatoxin-producing Escherichia coli (STEC) whereas the reminder comprises a heterogeneous group (here classified as Non-STEC-HUS). Renal impa...

journal_title：Frontiers in pediatrics

authors： Vaterodt L,Holle J,Hüseman D,Müller D,Thumfart J

更新日期：2018-08-07 00:00:00

abstract：:Background: To evaluate the effects of pressure levels on cerebral hemodynamics in premature infants receiving nasal continuous positive airway pressure (nCPAP) during the first 3 days of life. Methods: Forty-four preterm infants treated with nCPAP were divided into two groups: very preterm infants [gestational age 1 ...

journal_title：Frontiers in pediatrics

authors： Zhou H,Hou X,Cheng R,Zhao Y,Qiu J

更新日期：2020-08-21 00:00:00

abstract：Aim:The purpose of this study is to describe the development of an external 3-dimensional (3D) scanner as a noninvasive method for imaging chest wall deformities. It allows objective assessment, reconstruction of the area of interest, and evaluation of the severity of the deformity by using external indexes. External ...

journal_title：Frontiers in pediatrics

authors： Lain A,Garcia L,Gine C,Tiffet O,Lopez M

更新日期：2017-12-04 00:00:00

abstract：:Background and Aim: Intestinal failure-associated liver disease (IFALD) affects one-fifth of neonates receiving parenteral nutrition (PN) for more than 2 weeks. We aimed to define the effect of IFALD on hemostasis of preterm infants. Methods: This is an ancillary analysis of a prospective study aimed at defining coagu...

journal_title：Frontiers in pediatrics

authors： Ghirardello S,Raffaeli G,Scalambrino E,Cortesi V,Roggero P,Peyvandi F,Mosca F,Tripodi A

更新日期：2020-08-26 00:00:00

abstract：:Heart rate (HR) and blood pressure (BP) form the basis for monitoring the physiological state of patients. Although norms have been published for healthy and hospitalized children, little is known about their distributions in critically ill children. The objective of this study was to report the distributions of these...

journal_title：Frontiers in pediatrics

authors： Eytan D,Goodwin AJ,Greer R,Guerguerian AM,Laussen PC

更新日期：2017-03-17 00:00:00

abstract：:Minimal residual disease (MRD) by multiparametric flow cytometry (MFC) has been recently shown as a strong and independent prognostic marker of relapse in pediatric AML (pedAML) when measured at specific time points during Induction and/or Consolidation therapy. Hence, MFC-MRD has the potential to refine the current s...

journal_title：Frontiers in pediatrics

authors： Buldini B,Maurer-Granofszky M,Varotto E,Dworzak MN

更新日期：2019-10-11 00:00:00

abstract：BACKGROUND:Impaired sleep is associated with negative effects on quality of life and daytime functioning. Higher rates of sleep disturbance are reported in children with various developmental disorders. However, little is known about sleep in children with developmental coordination disorder (DCD), a condition characte...

journal_title：Frontiers in pediatrics

authors： Wiggs L,Sparrowhawk M,Barnett AL

更新日期：2016-08-04 00:00:00

abstract：:Nuclear factor kappa-B subunit 2 (NF-κB2/p100/p52), encoded by NFKB2 (MIM: 164012) belongs to the NF-κB family of transcription factors that play a critical role in inflammation, immunity, cell proliferation, differentiation and survival. Heterozygous C-terminal mutations in NFKB2 have been associated with early-onset...

journal_title：Frontiers in pediatrics

authors： Aird A,Lagos M,Vargas-Hernández A,Posey JE,Coban-Akdemir Z,Jhangiani S,Mace EM,Reyes A,King A,Cavagnaro F,Forbes LR,Chinn IK,Lupski JR,Orange JS,Poli MC

更新日期：2019-07-30 00:00:00

abstract：:Severe Combined Immunodeficiencies (SCID) are a heterogeneous group of monogenetic diseases. We describe the typical clinical presentation of patients with SCID as well as basic principles in diagnosis and therapy by hematopoietic stem cell transplantation. Therapeutic strategies may differ between subtypes and the in...

journal_title：Frontiers in pediatrics

authors： Haddad E,Hoenig M

更新日期：2019-11-19 00:00:00

abstract：:Objective: To investigate the relationship of overnutrition (obese and overweight) with severity of illness in children hospitalized with acute lower respiratory infections (ALRIs), frequency of viral coinfections and leptin levels. Methods: We studied 124 children <2 years old that were hospitalized for ALRI. Nutriti...

journal_title：Frontiers in pediatrics

authors： Arias-Bravo G,Valderrama G,Inostroza J,Reyes-Farías M,Garcia-Diaz DF,Zorondo-Rodríguez F,Fuenzalida LF

更新日期：2020-02-18 00:00:00

abstract：:Puberty is a sensitive period of life characterized by the appearance of secondary sex characteristics which leads to a complete sexual maturation. It physiologically starts between the age of 8 and 13 years in girls and 9 and 14 years in boys. In the last two decades, several studies have showed that start of puberty...

journal_title：Frontiers in pediatrics

authors： Farello G,Altieri C,Cutini M,Pozzobon G,Verrotti A

更新日期：2019-05-08 00:00:00