Vaccine Interactions With the Infant Microbiome: Do They Define Health and Disease?

abstract：:Aim: The aim of this study was to evaluate the surgical outcome, in terms of gait improvement, of endoscopic transverse Vulpius gastrocsoleus recession in children with cerebral palsy compared to the traditional open surgery. Methods: Twenty-seven children with cerebral palsy who had undergone endoscopic transverse Vu...

journal_title：Frontiers in pediatrics

authors： Kim DW,Kim HW,Yoon JY,Rhee I,Oh MK,Park KB

更新日期：2020-03-24 00:00:00

abstract：:Background: Pulmonary artery banding (PAB) is reported as an innovative strategy for children with end-stage heart failure (ESHF) to bridge to transplantation or recovery. We report our early experience with PAB to evaluate outcomes, indications, and limitations. Materials and Methods: This is a single-center prospect...

journal_title：Frontiers in pediatrics

authors： Di Candia A,Castaldi B,Bordin G,Cerutti A,Reffo E,Biffanti R,Di Salvo G,Vida VL,Padalino MA

更新日期：2020-07-16 00:00:00

abstract：:Introduction: The pediatric perineal microbiomes inhabit a dynamic environment with changes related to diet, toileting habits, and hormonal development. We hypothesized that next-generation sequencing would reveal different perineal bacterial signatures associated with developmental milestones in premenstrual females....

journal_title：Frontiers in pediatrics

authors： Lucas EJ,Ching CB,Saraswat S,Dabdoub SM,Kumar PP,Justice SS

更新日期：2020-12-08 00:00:00

abstract：:Acute myeloid leukemia (AML) is the second most common leukemia of childhood and is associated with high rates of chemotherapy resistance and relapse. Clinical outcomes for children with AML treated with maximally intensive multi-agent chemotherapy lag far behind those of children with the more common acute lymphoblas...

journal_title：Frontiers in pediatrics

authors： Sexauer AN,Tasian SK

更新日期：2017-11-20 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) is frequently associated with an increase in sympathetic tone. This may adversely affect cardiac autonomic control. Knowledge about the clinical impact of autonomic dysfunction in patients with PH is limited. We aimed to assess whether parameters of heart rate variability (HRV) ar...

journal_title：Frontiers in pediatrics

authors： Latus H,Bandorski D,Rink F,Tiede H,Siaplaouras J,Ghofrani A,Seeger W,Schranz D,Apitz C

更新日期：2015-07-07 00:00:00

abstract：:Vascular tumors in pediatric patients are an important entity for the clinician to recognize and correctly diagnose. They may present at birth or develop at any point during infancy, childhood, or adolescence. Most are benign, but even benign lesions may have significant morbidity without proper intervention. Malignan...

journal_title：Frontiers in pediatrics

authors： Hinen HB,Trenor CC 3rd,Wine Lee L

更新日期：2020-10-22 00:00:00

abstract：:Autosomal recessive polycystic kidney disease (ARPKD) is a rare monogenic disease with a severe phenotype often presenting prenatally or in early childhood. With its obligate renal and hepatic involvement, ARPKD is one of the most important indications for liver and/or kidney transplantation in childhood. Marked pheno...

journal_title：Frontiers in pediatrics

authors： Ebner K,Schaefer F,Liebau MC,ARegPKD Consortium.

更新日期：2017-02-16 00:00:00

abstract：:Introduction: Acute respiratory infections with cough (ARIwC) contribute considerably to childhood morbidity, yet few studies have examined the cost of these illnesses among Australian children. Moreover, of the few studies that have, none are inclusive of Aboriginal and/or Torres Strait Islander children, despite thi...

journal_title：Frontiers in pediatrics

authors： Lovie-Toon YG,McPhail SM,Au-Yeung YT,Hall KK,Chang AB,Vagenas D,Otim ME,O'Grady KF

更新日期：2018-12-03 00:00:00

abstract：:In recent years, there have been major advances in the application of non-invasive techniques to predict pregnancy-related complications, for example by measuring cell-free RNA (cfRNA) in maternal blood. In contrast to cell-free DNA (cfDNA), which is already in clinical use to diagnose fetal aneuploidy, circulating RN...

journal_title：Frontiers in pediatrics

authors： Moufarrej MN,Wong RJ,Shaw GM,Stevenson DK,Quake SR

更新日期：2020-12-14 00:00:00

abstract：:Puberty is a sensitive period of life characterized by the appearance of secondary sex characteristics which leads to a complete sexual maturation. It physiologically starts between the age of 8 and 13 years in girls and 9 and 14 years in boys. In the last two decades, several studies have showed that start of puberty...

journal_title：Frontiers in pediatrics

authors： Farello G,Altieri C,Cutini M,Pozzobon G,Verrotti A

更新日期：2019-05-08 00:00:00

abstract：:Aim: The aim of this study was to present primary outcomes of autologous bone marrow mononuclear cell (BMMNC) transplantation to improve neurological sequelae in four children with intracranial hemorrhage (ICH) incidence during the neonatal period. Methods: GMFM88 and modified Ashworth score were used to assess motor ...

journal_title：Frontiers in pediatrics

authors： Liem NT,Huyen TL,Huong LT,Doan NV,Anh BV,Anh NTP,Tung DT

更新日期：2020-01-24 00:00:00

abstract：:Although antibiotics confer significant health benefits in treating or preventing bacterial infections, an accumulating wealth of evidence illustrates their detrimental effect on host-microbiota homeostasis, posing a serious menace to the global public health. In recent years, it is becoming evident that infants, who ...

journal_title：Frontiers in pediatrics

authors： Shekhar S,Petersen FC

更新日期：2020-10-15 00:00:00

abstract：:Exertional dyspnea is a common complaint in general pediatric practice. While a high proportion of the general pediatric population has asthma, other diagnoses, including exercise-induced laryngeal obstruction should be considered, especially when asthma therapy is not sufficient to control symptoms. This review descr...

journal_title：Frontiers in pediatrics

authors： Olin JT

更新日期：2019-03-01 00:00:00

abstract：:We constructed an optimal machine learning (ML) method for predicting intravenous immunoglobulin (IVIG) resistance in children with Kawasaki disease (KD) using commonly available clinical and laboratory variables. We retrospectively collected 98 clinical records of hospitalized children with KD (2-109 months of age). ...

journal_title：Frontiers in pediatrics

authors： Kuniyoshi Y,Tokutake H,Takahashi N,Kamura A,Yasuda S,Tashiro M

更新日期：2020-12-03 00:00:00

abstract：:Background: Eculizumab has dramatically changed poor outcomes of complement-mediated atypical hemolytic uremic syndrome (aHUS) as first-line treatment. Discontinuation of eculizumab remains challenging, and doctor's visits every 2 weeks for intravenous injection because of standard dosing protocols is a huge burden. T...

journal_title：Frontiers in pediatrics

authors： Saida K,Fukuda T,Mizuno K,Ogura M,Kamei K,Ito S

更新日期：2019-12-17 00:00:00

abstract：:Background: Although most preterm infants breathe at birth, their respiratory drive is weak and supplemental oxygen is often needed to overcome hypoxia. This could in turn lead to hyperoxia. To reduce the risk of hyperoxia, currently an initial low oxygen concentration (21-30%) is recommended during stabilization at b...

journal_title：Frontiers in pediatrics

authors： Dekker J,Hooper SB,Giera M,McGillick EV,Hutten GJ,Onland W,van Kaam AH,Te Pas AB

更新日期：2019-05-07 00:00:00

abstract：:A subset of patients with Ataxia-Telangiectasia (A-T) have dramatically reduced levels of IgG, IgA, and IgE with retained or elevated IgM levels. Several reports suggest that these A-T patients with a "hyper-IgM phenotype" (HIgM) suffer more clinical immunologic consequences than other A-T patients. The immunopatholog...

journal_title：Frontiers in pediatrics

authors： Meyer AK,Banks M,Nadasdy T,Clark JJ,Zheng R,Gelfand EW,Abbott JK

更新日期：2019-10-24 00:00:00

abstract：:X-linked lymphoproliferative disease (XLP) is one of the X-linked primary immunodeficiency diseases (PIDs) with defective immune response to Epstein-Barr virus (EBV) infection. Chronic active EBV infection (CAEBV) and EBV-hemophagocytic lymphohistiocytosis (HLH) are recognized as systemic EBV-positive T-cell and natur...

journal_title：Frontiers in pediatrics

authors： Ishimura M,Eguchi K,Shiraishi A,Sonoda M,Azuma Y,Yamamoto H,Imadome KI,Ohga S

更新日期：2019-05-21 00:00:00

abstract：:The term osteopetrosis describes a group of rare hereditary diseases of the skeleton, characterized by an increase in bone density, caused by a defect in the development or function of osteoclasts. It comprises a clinically and genetically heterogeneous conditions ranging from infantile onset life-threatening forms to...

journal_title：Frontiers in pediatrics

authors： di Palmo E,Gallucci M,Tronconi E,Bergamaschi R,Cazzato S,La Scola C,Ricci G,Pession A

更新日期：2018-07-31 00:00:00

abstract：:Background: Precocious and early puberty are reported findings in children with pre-existing medical conditions including certain syndromes. Series pertaining to such situations are limited. Methods: A retrospective, single-center study was conducted on children with central precocious puberty (onset before the age of...

journal_title：Frontiers in pediatrics

authors： Winter S,Durand A,Brauner R

更新日期：2019-02-14 00:00:00

abstract：:Heart rate (HR) and blood pressure (BP) form the basis for monitoring the physiological state of patients. Although norms have been published for healthy and hospitalized children, little is known about their distributions in critically ill children. The objective of this study was to report the distributions of these...

journal_title：Frontiers in pediatrics

authors： Eytan D,Goodwin AJ,Greer R,Guerguerian AM,Laussen PC

更新日期：2017-03-17 00:00:00

abstract：:Informed consent is a process ensuring that subjects enrolled in research are appropriately informed of the risks and benefits. While this process is well-defined when it is possible and practical to obtain consent prior to the research intervention, it can be less clear in cases of deferred or waived consent. Definin...

journal_title：Frontiers in pediatrics

authors： Rich WD,Katheria AC

更新日期：2019-11-26 00:00:00

abstract：:Abdominal lipoblastomas are uncommon soft tissue tumors in children and rarely arise from the mesentery. Due to intraabdominal location and slow growth, these masses can go unnoticed for long periods of time and often found on surgical exploration. We present a case of a 12-year-old male with years of abdominal disten...

journal_title：Frontiers in pediatrics

authors： Squillaro AI,Chow MD,Arias F,Sadimin ET,Lee YH

更新日期：2020-07-24 00:00:00

abstract：:Objective: The effective diagnosis of Mycoplasma pneumoniae (MP) pneumonia (MPP) in children has been hampered by the difficulty of achieving an early diagnosis. The simultaneous amplification and testing (SAT) has the potential for early diagnosis of MP in children. Methods: Of the 1,180 children enrolled in this stu...

journal_title：Frontiers in pediatrics

authors： Li J,Sun L,Wu X,Guo Y,Jiao W,Xiao J,Xu B,Shen A

更新日期：2019-10-25 00:00:00

abstract：:Introduction: Allostatic load (AL) refers to the physiological response associated with the burden of chronic stress. Excessive weight is an important source of physiological stress that promotes a detrimental chronic low-inflammation state. In order to define a correlation between cumulative biological dysregulation ...

journal_title：Frontiers in pediatrics

authors： Calcaterra V,Vinci F,Casari G,Pelizzo G,de Silvestri A,De Amici M,Albertini R,Regalbuto C,Montalbano C,Larizza D,Cena H

更新日期：2019-08-07 00:00:00

abstract：:Background: To evaluate the effects of pressure levels on cerebral hemodynamics in premature infants receiving nasal continuous positive airway pressure (nCPAP) during the first 3 days of life. Methods: Forty-four preterm infants treated with nCPAP were divided into two groups: very preterm infants [gestational age 1 ...

journal_title：Frontiers in pediatrics

authors： Zhou H,Hou X,Cheng R,Zhao Y,Qiu J

更新日期：2020-08-21 00:00:00

abstract：Objectives:Disparities in obesity care exist among African-American children and adults. We sought to test the feasibility of a pilot program, a 1-year family-based intervention for African-American families with obesity [shape up and eat right (SUPER)], adopting the shared medical appointment model (SMA) at an urban s...

journal_title：Frontiers in pediatrics

authors： Srivastava G,Palmer KD,Ireland KA,McCarthy AC,Donovan KE,Manders AJ,McDougal J,Lenders CM,Apovian CM

更新日期：2018-04-12 00:00:00

abstract：:DNA repair defects are inborn errors of immunity that result in increased apoptosis and oncogenesis. DNA Ligase 4-deficient patients suffer from a wide range of clinical manifestations since early in life, including: microcephaly, dysmorphic facial features, growth failure, developmental delay, mental retardation; hip...

journal_title：Frontiers in pediatrics

authors： Staines Boone AT,Chinn IK,Alaez-Versón C,Yamazaki-Nakashimada MA,Carrillo-Sánchez K,García-Cruz MLH,Poli MC,González Serrano ME,Medina Torres EA,Muzquiz Zermeño D,Forbes LR,Espinosa-Rosales FJ,Espinosa-Padilla SE,Orange JS,Lu

更新日期：2019-01-21 00:00:00

abstract：:Background: Improved diagnostic tests are needed for the early identification of Mycobacterium tuberculosis-infected young children exposed to an active TB (aTB) index case. We aimed to compare the diagnostic accuracy of new blood-based tests to that of the tuberculin skin test (TST) for the identification of all infe...

journal_title：Frontiers in pediatrics

authors： Dreesman A,Dirix V,Smits K,Corbière V,Van Praet A,Debulpaep S,De Schutter I,Felderhof MK,Malfroot A,Singh M,Locht C,Mouchet F,Mascart F

更新日期：2019-07-25 00:00:00

abstract：:Ceftolozane-tazobactam is a novel fifth-generation cephalosporin/β-lactamase inhibitor combination recently approved for treatment of both complicated intra-abdominal and urinary tract infections in adults. Considering its potent bactericidal activity against Pseudomonas aeruginosa, it might represent an important opt...

journal_title：Frontiers in pediatrics

authors： Garazzino S,Altieri E,Silvestro E,Pruccoli G,Scolfaro C,Bignamini E

更新日期：2020-05-05 00:00:00