Abstract:
:Prenatal iron and folic acid (IFA) supplements are offered free to all pregnant women in Malawi to reduce maternal anemia and improve birth outcomes. We investigated the association between self-reported compliance to IFA intake and risk of low birth weight (LBW). Pregnant women who attended Bwaila Maternity Wing of Lilongwe District Hospital for delivery were recruited (n = 220). We used a questionnaire to collect self-reported information on IFA use and maternal sociodemographic data. Before delivery, blood samples for maternal hemoglobin (Hb) and folate status, and upon delivery, birth weight, and other newborn anthropometrics were measured. We used multivariable logistic regression to determine risk of LBW by prenatal IFA intake. The self-reported number of IFA pills taken during pregnancy was positively associated with Hb, but not serum and RBC folate concentration: <45, 45⁻89 and ≥90 pills taken corresponded with mean (SD) Hb 10.7 (1.6), 11.3 (1.8), and 11.7 (1.6) g/dL, respectively (p = 0.006). The prevalence of LBW was 20.1%, 13.5% and 5.6% for those who reported taking IFA pills <45, 45⁻89, and ≥90 pills, respectively (p = 0.027). Taking >60 IFA pills reduced risk of LBW delivery (OR (95% CI) = 0.15 (0.03⁻0.70), p = 0.033) than taking ≤30 pills. Self-reported compliance to IFA use is valid for assessing prenatal supplement program in Malawi, especially Hb status, and can reduce the rate of LBW.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Chikakuda AT,Shin D,Comstock SS,Song S,Song WOdoi
10.3390/nu10091275subject
Has Abstractpub_date
2018-09-10 00:00:00issue
9issn
2072-6643pii
nu10091275journal_volume
10pub_type
杂志文章相关文献
Nutrients文献大全abstract::In 2016⁻2017, we conducted and published a systematic review on caffeine safety that set out to determine whether conclusions that were presented in the heavily cited Health Canada assessment, remain supported by more recent data. To that end, we reviewed data from 380 studies published between June 2001 and June 2015...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10101536
更新日期:2018-10-18 00:00:00
abstract::Chronic smokers have a greater risk for altered chemosensation, unhealthy dietary patterns, and excessive adiposity. In an observational study of chronic smokers, we modeled relationships between chemosensation, fat/carbohydrate liking, smoking-associated dietary behaviors, and body mass index (BMI). Also tested in th...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11020271
更新日期:2019-01-26 00:00:00
abstract:BACKGROUND:The influence of diet in pregnant women on the immune tolerance process is intricate. Food-specific immunoglobulin G (IgG) was associated with exposure to particular food antigens. The IgG antibodies can cross the placental barrier and enter into the colostrum, and maternal IgG is amply present in breast mil...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11051096
更新日期:2019-05-17 00:00:00
abstract::Human milk is the ideal nutrition source for healthy infants during the first six months of life and a detailed characterisation of the composition of milk from mothers that deliver prematurely (<37 weeks gestation), and of how human milk changes during lactation, would benefit our understanding of the nutritional req...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8050304
更新日期:2016-05-19 00:00:00
abstract::Skeletal muscle plays a relevant role in metabolic flexibility and fuel usage and the associated muscle metabolic inflexibility due to high-fat diets contributing to obesity and type 2 diabetes. Previous research from our group indicates that a high-fat and rapid-digesting carbohydrate diet during pregnancy promotes a...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12020528
更新日期:2020-02-19 00:00:00
abstract::Both type 2 prediabetes/diabetes (T2DM) and new-onset prediabetes/diabetes after acute pancreatitis (NODAP) are characterized by impaired tissue sensitivity to insulin action. Although the outcomes of NODAP and T2DM are different, it is unknown whether drivers of insulin resistance are different in the two types of di...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12092883
更新日期:2020-09-21 00:00:00
abstract::This study investigated the effects of a single dose of arginine (Arg) administration at the beginning of sepsis on CD4+ T-cell regulation and liver inflammation in C57BL/6J mice. Mice were divided into normal control (NC), sham (SH), sepsis saline (SS), and sepsis Arg (SA) groups. An inducible nitric oxide (NO) synth...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12041047
更新日期:2020-04-10 00:00:00
abstract::The novel coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has engulfed the world, affecting more than 180 countries. As a result, there has been considerable economic distress globally and a significant loss of life. Sadly, the vulnerable and immunocomprom...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12051466
更新日期:2020-05-19 00:00:00
abstract::Unlike milk-based infant formulas, soy-based infant formulas containing supplemental fructooligosaccharides (FOS) have not been clinically evaluated. A randomized, double-blind, 28 day parallel feeding trial compared gastrointestinal (GI) tolerance and hydration in healthy term newborn infants fed either a commerciali...
journal_title:Nutrients
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.3390/nu7043022
更新日期:2015-04-22 00:00:00
abstract::Essential amino acids (EAA) consist of a group of nine amino acids that animals are unable to synthesize via de novo pathways. Recently, it has been found that most metazoans lack the same set of enzymes responsible for the de novo EAA biosynthesis. Here we investigate the sequence conservation and evolution of all th...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7010001
更新日期:2014-12-24 00:00:00
abstract::The effect of the betaine: homocysteine methyltransferase BHMT c.716G>A (G: guanosine; A: adenosine) single nucleotide polymorphism (SNP) on the BHMT pathway is unknown during pregnancy. We hypothesised that it impairs betaine to dimethylglycine conversion and that folate status modifies its effect. We studied 612 wom...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8100621
更新日期:2016-10-09 00:00:00
abstract::This scoping review examines the interaction of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) and genetic variants of various types of cancers. A comprehensive search was performed to identify controlled and observational studies conducted through August 2017. Eighteen unique studies were included: breast...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12061647
更新日期:2020-06-02 00:00:00
abstract::As a sugar additive, fructose is widely used in processed foods and beverages. Excessive fructose consumption can cause hepatic steatosis and dyslipidemia, leading to the development of metabolic syndrome. Recent research revealed that fructose-induced nonalcoholic fatty liver disease (NAFLD) is related to several pat...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu9020096
更新日期:2017-01-31 00:00:00
abstract::Vitamin A or retinol which is the natural precursor of several biologically active metabolites can be considered the most multifunctional vitamin in mammals. Its deficiency is currently, along with protein malnutrition, the most serious and common nutritional disorder worldwide. It is necessary for normal embryonic de...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu6114984
更新日期:2014-11-10 00:00:00
abstract:BACKGROUND:Oral uptake of lycopene has been shown to be beneficial for preventing myocardial ischemia-reperfusion (I/R) injury. However, the strong first-pass metabolism of lycopene influences its bioavailability and impedes its clinic application. In this study, we determined an intravenous (IV) administration dose of...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8030138
更新日期:2016-03-03 00:00:00
abstract::Quercetin, a medicinally important member of the flavonoid family, is one of the most prominent dietary antioxidants. It is present in a variety of foods-including fruits, vegetables, tea, wine, as well as other dietary supplements-and is responsible for various health benefits. Numerous pharmacological effects of que...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu8090529
更新日期:2016-08-29 00:00:00
abstract::Bread is a vehicle for a range of nutrients within the Australian diet, but has been the target of negative press. The aim of this study was to examine bread products, particularly white, whole grain and gluten-free loaves, including nutrients, health claims and Health Star Rating (HSR). An audit of four supermarkets ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10081106
更新日期:2018-08-16 00:00:00
abstract::The central and peripheral effects of caffeine remain debatable. We verified whether increases in endurance performance after caffeine ingestion occurred together with changes in primary motor cortex (MC) and prefrontal cortex (PFC) activation, neuromuscular efficiency (NME), and electroencephalography-electromyograph...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11102471
更新日期:2019-10-15 00:00:00
abstract::Vascular calcification (VC) as a manifestation of perturbed mineral balance, is associated with aging, diabetes and kidney dysfunction, as well as poorer patient outcomes. Due to the current limited understanding of the pathophysiology of vascular calcification, the development of effective preventative and therapeuti...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10050652
更新日期:2018-05-22 00:00:00
abstract::Members of the genus Curcuma L. have been used in traditional medicine for centuries for treating gastrointestinal disorders, pain, inflammatory conditions, wounds, and for cancer prevention and antiaging, among others. Many of the biological activities of Curcuma species can be attributed to nonvolatile curcuminoids,...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10091196
更新日期:2018-09-01 00:00:00
abstract::Dietary patterns may have a role in the prevention of functional gastrointestinal disorders (FGIDs). The current study aimed at examining the association between FGIDs and adherence to the Mediterranean diet (MD) among elementary school children (ESC), as well as high school students (HSS). In a prospective cohort stu...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11061283
更新日期:2019-06-06 00:00:00
abstract::Healthy microbiota is a critical mediator in maintaining health and it is supposed that dysbiosis could have a role in the pathogenesis of a number of diseases. Evidence supports the hypothesis that maternal dysbiosis could act as a trigger for preterm birth; aberrant colonization of preterm infant gut might have a ro...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu11061273
更新日期:2019-06-05 00:00:00
abstract::Although the correlation between polyunsaturated fatty acids (PUFA) and the production of pro- and anti-inflammatory metabolites is well documented, little is known about the simultaneous effect of different PUFA on the production of cyclooxygenase and lipoxygenase metabolites. The present research examines the associ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11050966
更新日期:2019-04-27 00:00:00
abstract:UNLABELLED:Hormonal contraceptives may produce side effects that deter women from their use as a method of family planning. In nutritionally vulnerable populations these effects may be more pronounced due to micronutrient deficiencies and health status. Previous studies have been unable to resolve whether micronutrient...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu6093353
更新日期:2014-08-26 00:00:00
abstract::Severe acute respiratory syndrome coronavirus type (SARS-CoV2, also known as COVID-19), which is the latest pandemic infectious disease, constitutes a serious risk to human health. SARS-CoV2 infection causes immune activation and systemic hyperinflammation which can lead to respiratory distress syndrome (ARDS). ARDS v...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12113512
更新日期:2020-11-14 00:00:00
abstract::There is currently little information on changes in vitamin D status during pregnancy and its predictors. The aim was to study the determinants of change in vitamin D status during pregnancy and of vitamin D deficiency (<30 nmol/L) in early pregnancy. Blood was drawn in the first (T1) and third trimester (T3). Serum 2...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8100655
更新日期:2016-10-22 00:00:00
abstract::Gluten-related neurological disorders (GRND) represent a spectrum of neurological manifestations that are triggered by gluten. In coeliac disease, a T-cell mediated enteropathy is triggered by gluten in genetically predisposed individuals. The underlying pathological mechanism of the neurological dysfunction is not ye...
journal_title:Nutrients
pub_type: 杂志文章,meta分析
doi:10.3390/nu12030822
更新日期:2020-03-20 00:00:00
abstract::Coronary artery calcification (CAC) develops early in the pathogenesis of atherosclerosis and is a strong and independent predictor of cardiovascular disease (CVD). Arterial calcification is caused by an imbalance in calcification regulatory mechanisms. An important inhibitor of calcification is vitamin K-dependent ma...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu7115443
更新日期:2015-10-28 00:00:00
abstract::Research suggests that attention, mood, and satiety can be influenced by meal composition and postprandial activity. The present study examined whether this hypothesis applies to persons with a risk phenotype for the development of cardiovascular/neurodegenerative diseases. A randomized crossover trial was conducted i...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11102294
更新日期:2019-09-26 00:00:00
abstract::In a study using a randomized crossover approach, cyclists (n = 20, overnight fasted) engaged in three 75 km time trials while ingesting water (WAT) or carbohydrate (0.2 g/kg every 15 min) from bananas (BAN) or a 6% sugar beverage (SUG). Blood samples were collected pre-exercise and 0 h, 1.5 h, and 21 h post-exercise ...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu10111658
更新日期:2018-11-04 00:00:00