Social determinants of mental disorders and the Sustainable Development Goals: a systematic review of reviews.

abstract：BACKGROUND:Provision of early intervention services has increased the rate of social recovery in patients with first-episode psychosis; however, many individuals have continuing severe and persistent problems with social functioning. We aimed to assess the efficacy of early intervention services augmented with social r...

journal_title：The lancet. Psychiatry

authors： Fowler D,Hodgekins J,French P,Marshall M,Freemantle N,McCrone P,Everard L,Lavis A,Jones PB,Amos T,Singh S,Sharma V,Birchwood M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The PACE trial found that, when added to specialist medical care (SMC), cognitive behavioural therapy (CBT), or graded exercise therapy (GET) were superior to adaptive pacing therapy (APT) or SMC alone in improving fatigue and physical functioning in people with chronic fatigue syndrome 1 year after randomis...

journal_title：The lancet. Psychiatry

authors： Sharpe M,Goldsmith KA,Johnson AL,Chalder T,Walker J,White PD

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The conceptualisation of transgender identity as a mental disorder has contributed to precarious legal status, human rights violations, and barriers to appropriate health care among transgender people. The proposed reconceptualisation of categories related to transgender identity in WHO's forthcoming Interna...

journal_title：The lancet. Psychiatry

authors： Robles R,Fresán A,Vega-Ramírez H,Cruz-Islas J,Rodríguez-Pérez V,Domínguez-Martínez T,Reed GM

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:The benefits and safety of medications for attention-deficit hyperactivity disorder (ADHD) remain controversial, and guidelines are inconsistent on which medications are preferred across different age groups. We aimed to estimate the comparative efficacy and tolerability of oral medications for ADHD in child...

journal_title：The lancet. Psychiatry

authors： Cortese S,Adamo N,Del Giovane C,Mohr-Jensen C,Hayes AJ,Carucci S,Atkinson LZ,Tessari L,Banaschewski T,Coghill D,Hollis C,Simonoff E,Zuddas A,Barbui C,Purgato M,Steinhausen HC,Shokraneh F,Xia J,Cipriani A

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Early social deprivation can negatively affect domains of functioning. We examined psychopathology at age 12 years in a cohort of Romanian children who had been abandoned at birth and placed into institutional care, then assigned either to be placed in foster care or to care as usual. METHODS:We used follow...

journal_title：The lancet. Psychiatry

authors： Humphreys KL,Gleason MM,Drury SS,Miron D,Nelson CA 3rd,Fox NA,Zeanah CH

更新日期：2015-07-01 00:00:00

abstract：:Suicide is the 15th leading cause of death worldwide, with over 75% of suicides occurring in low-income and middle-income countries. Nonetheless, evidence on the association between suicide and poverty in low-income and middle-income countries is scarce. We did a systematic review to understand the association between...

journal_title：The lancet. Psychiatry

authors： Iemmi V,Bantjes J,Coast E,Channer K,Leone T,McDaid D,Palfreyman A,Stephens B,Lund C

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Smoke-free policies are important to protect health and reduce health inequalities. A major barrier to policy implementation in psychiatric hospitals is staff concern that physical violence will increase. We aimed to assess the effect of implementing a comprehensive smoke-free policy on rates of physical ass...

journal_title：The lancet. Psychiatry

authors： Robson D,Spaducci G,McNeill A,Stewart D,Craig TJK,Yates M,Szatkowski L

更新日期：2017-07-01 00:00:00

abstract：:The care of people with first-episode mania has been overlooked in comparison with the care of patients with other non-affective psychoses, despite evidence suggesting targeted treatments might be of benefit for this patient group. In this Personal View, we outline the general epidemiology of first-episode mania in th...

journal_title：The lancet. Psychiatry

authors： Jauhar S,Ratheesh A,Davey C,Yatham LN,McGorry PD,McGuire P,Berk M,Young AH

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Statins have shown both protective and adverse associations with neuropsychiatric outcomes. We aimed to examine the possible associations between statins and suicidality, depression, anxiety, and seizures. METHODS:Using Swedish national registers, we linked data on dispensed statin prescriptions with data o...

journal_title：The lancet. Psychiatry

authors： Molero Y,Cipriani A,Larsson H,Lichtenstein P,D'Onofrio BM,Fazel S

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Many studies suggest that electroencephalographic (EEG) neurofeedback might be beneficial in the treatment of attention-deficit hyperactivity disorder (ADHD). However, numbers of well controlled studies are low and neurofeedback techniques are regarded as highly controversial. The present trial examined the ...

journal_title：The lancet. Psychiatry

authors： Schönenberg M,Wiedemann E,Schneidt A,Scheeff J,Logemann A,Keune PM,Hautzinger M

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Cognitive behaviour therapy (CBT) added to specialist medical care (SMC), or graded exercise therapy (GET) added to SMC, are more effective in reducing fatigue and improving physical function than both adaptive pacing therapy (APT) plus SMC and SMC alone for chronic fatigue syndrome. We investigate putative ...

journal_title：The lancet. Psychiatry

authors： Chalder T,Goldsmith KA,White PD,Sharpe M,Pickles AR

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:The first episode of psychosis is a crucial period when early intervention can alter the trajectory of the young person's ongoing mental health and general functioning. After an investigation into completed suicides in the Early Psychosis Prevention and Intervention Centre (EPPIC) programme, the intensive ca...

journal_title：The lancet. Psychiatry

authors： Brewer WJ,Lambert TJ,Witt K,Dileo J,Duff C,Crlenjak C,McGorry PD,Murphy BP

更新日期：2015-01-01 00:00:00

abstract：:Contemporary psychiatry faces major challenges. Its syndrome-based disease classification is not based on mechanisms and does not guide treatment, which largely depends on trial and error. The development of therapies is hindered by ignorance of potential beneficiary patient subgroups. Neuroscientific and genetics res...

journal_title：The lancet. Psychiatry

authors： Stephan KE,Bach DR,Fletcher PC,Flint J,Frank MJ,Friston KJ,Heinz A,Huys QJM,Owen MJ,Binder EB,Dayan P,Johnstone EC,Meyer-Lindenberg A,Montague PR,Schnyder U,Wang XJ,Breakspear M

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Long-standing concerns exist about reverse causation and residual confounding in the prospective association between job strain and risk of future common mental disorders. We aimed to address these concerns through analysis of data collected in the UK National Child Development Study, a large British cohort ...

journal_title：The lancet. Psychiatry

authors： Harvey SB,Sellahewa DA,Wang MJ,Milligan-Saville J,Bryan BT,Henderson M,Hatch SL,Mykletun A

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:With a lifetime risk for major depressive disorder of up to 50%, depression is a common comorbidity in multiple sclerosis but remains widely underdiagnosed and untreated. We investigated the potential of a fully automated, internet-based, cognitive behavioural therapy programme, Deprexis, to reduce depressiv...

journal_title：The lancet. Psychiatry

authors： Fischer A,Schröder J,Vettorazzi E,Wolf OT,Pöttgen J,Lau S,Heesen C,Moritz S,Gold SM

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:People living in group situations or with dementia are more vulnerable to infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Older people and those with multimorbidity have higher mortality if they become infected than the general population. However, no systematic study exists of C...

journal_title：The lancet. Psychiatry

authors： Livingston G,Rostamipour H,Gallagher P,Kalafatis C,Shastri A,Huzzey L,Liu K,Sommerlad A,Marston L

更新日期：2020-12-01 00:00:00

abstract：:Autism spectrum conditions comprise a set of early-onset neurodevelopmental syndromes with a prevalence of 1% across all ages. First diagnosis in adulthood has finally become recognised as an important clinical issue due to the increasing awareness of autism, broadening of diagnostic criteria, and the introduction of ...

journal_title：The lancet. Psychiatry

authors： Lai MC,Baron-Cohen S

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Although clozapine is the treatment of choice for treatment-refractory schizophrenia, 30-40% of patients have an insufficient response, and others are unable to tolerate it. Evidence for any augmentation strategies is scarce. We aimed to determine whether cognitive behavioural therapy (CBT) is an effective t...

journal_title：The lancet. Psychiatry

authors： Morrison AP,Pyle M,Gumley A,Schwannauer M,Turkington D,MacLennan G,Norrie J,Hudson J,Bowe SE,French P,Byrne R,Syrett S,Dudley R,McLeod HJ,Griffiths H,Barnes TRE,Davies L,Kingdon D,FOCUS trial group.

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Many people with dementia living in care homes have distressing and costly agitation symptoms. Interventions should be efficacious, scalable, and feasible. METHODS:We did a parallel-group, cluster-randomised controlled trial in 20 care homes across England. Care homes were eligible if they had 17 residents ...

journal_title：The lancet. Psychiatry

authors： Livingston G,Barber J,Marston L,Stringer A,Panca M,Hunter R,Cooper C,Laybourne A,La Frenais F,Reeves S,Manela M,Lambe K,Banerjee S,Rapaport P

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Autism spectrum disorder (ASD) phenomenology is reported to be more common in individuals with some genetic syndromes than in the general population; however, no meta-analysis has provided prevalence data within and between syndromes. In this systematic review and meta-analysis, we aimed to synthesise data f...

journal_title：The lancet. Psychiatry

authors： Richards C,Jones C,Groves L,Moss J,Oliver C

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Many older adults with major depression, particularly veterans, do not have access to evidence-based psychotherapy. Telemedicine could increase access to best-practice care for older adults facing barriers of mobility, stigma, and geographical isolation. We aimed to establish non-inferiority of behavioural a...

journal_title：The lancet. Psychiatry

authors： Egede LE,Acierno R,Knapp RG,Lejuez C,Hernandez-Tejada M,Payne EH,Frueh BC

更新日期：2015-08-01 00:00:00

abstract：:Over the past decade, concussion has become the most widely discussed injury in contact sports. However, concussions also occur in several other settings, such as non-contact sports, elderly individuals, young children, military personnel, and victims of domestic violence. Concussion is frequently undiagnosed as a cau...

journal_title：The lancet. Psychiatry

authors： Radhakrishnan R,Garakani A,Gross LS,Goin MK,Pine J,Slaby AE,Sumner CR,Baron DA

更新日期：2016-12-01 00:00:00

abstract：:More than 10 million people are imprisoned worldwide, and the prevalence of all investigated mental disorders is higher in prisoners than in the general population. Although the extent to which prison increases the incidence of mental disorders is uncertain, considerable evidence suggests low rates of identification a...

journal_title：The lancet. Psychiatry

authors： Fazel S,Hayes AJ,Bartellas K,Clerici M,Trestman R

更新日期：2016-09-01 00:00:00

abstract：:The ubiquitin-proteasome system is a master regulator of neural development and the maintenance of brain structure and function. It influences neurogenesis, synaptogenesis, and neurotransmission by determining the localisation, interaction, and turnover of scaffolding, presynaptic, and postsynaptic proteins. Moreover,...

journal_title：The lancet. Psychiatry

authors： Luza S,Opazo CM,Bousman CA,Pantelis C,Bush AI,Everall IP

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:In view of the high co-occurrence of depression and insomnia, a novel way to reduce the risk of escalating depression might be to offer an insomnia intervention. We aimed to assess whether an online self-help insomnia program could reduce depression symptoms. METHODS:We did this randomised controlled trial ...

journal_title：The lancet. Psychiatry

authors： Christensen H,Batterham PJ,Gosling JA,Ritterband LM,Griffiths KM,Thorndike FP,Glozier N,O'Dea B,Hickie IB,Mackinnon AJ

更新日期：2016-04-01 00:00:00

abstract：:Neurodevelopmental disorders such as attention deficit hyperactivity disorder (ADHD) and autism spectrum disorder, although most commonly considered in childhood, can be lifelong conditions. In this Personal View that is shaped by clinical experience and research, we adopt a conceptual approach. First, we discuss what...

journal_title：The lancet. Psychiatry

authors： Thapar A,Cooper M,Rutter M

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Use of involuntary psychiatric hospitalisation varies widely within and between countries. The factors that place individuals and populations at increased risk of involuntary hospitalisation are unclear, and evidence is needed to understand these disparities and inform development of interventions to reduce ...

journal_title：The lancet. Psychiatry

authors： Walker S,Mackay E,Barnett P,Sheridan Rains L,Leverton M,Dalton-Locke C,Trevillion K,Lloyd-Evans B,Johnson S

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Exercise is known to be associated with reduced risk of all-cause mortality, cardiovascular disease, stroke, and diabetes, but its association with mental health remains unclear. We aimed to examine the association between exercise and mental health burden in a large sample, and to better understand the infl...

journal_title：The lancet. Psychiatry

authors： Chekroud SR,Gueorguieva R,Zheutlin AB,Paulus M,Krumholz HM,Krystal JH,Chekroud AM

更新日期：2018-09-01 00:00:00

abstract：:This Review reports on a scoping review followed by a systematic review to consider interventions designed to address or manage depression or anxiety in children and young people up to the age of 25 years without the need to involve mental health professionals. The scoping review identified 132 approaches, 103 of whic...

journal_title：The lancet. Psychiatry

authors： Wolpert M,Dalzell K,Ullman R,Garland L,Cortina M,Hayes D,Patalay P,Law D

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Depressive symptoms are a major cause of disability in bipolar disorder and there are few safe and effective treatments. The combination of lamotrigine plus quetiapine potentially offers improved outcomes for people with bipolar depression. We aimed to determine if combination therapy with quetiapine plus la...

journal_title：The lancet. Psychiatry

authors： Geddes JR,Gardiner A,Rendell J,Voysey M,Tunbridge E,Hinds C,Yu LM,Hainsworth J,Attenburrow MJ,Simon J,Goodwin GM,Harrison PJ,CEQUEL Investigators and Collaborators.

更新日期：2016-01-01 00:00:00