当前位置： SCI文献检索 > NeuroImage-Clinical期刊下所有文献 > Sleep onset uncovers thalamic abnormalities in patients with idiopathic generalised epilepsy.

Sleep onset uncovers thalamic abnormalities in patients with idiopathic generalised epilepsy.

Abstract：

:The thalamus is crucial for sleep regulation and the pathophysiology of idiopathic generalised epilepsy (IGE), and may serve as the underlying basis for the links between the two. We investigated this using EEG-fMRI and a specific emphasis on the role and functional connectivity (FC) of the thalamus. We defined three types of thalamic FC: thalamocortical, inter-hemispheric thalamic, and intra-hemispheric thalamic. Patients and controls differed in all three measures, and during wakefulness and sleep, indicating disorder-dependent and state-dependent modification of thalamic FC. Inter-hemispheric thalamic FC differed between patients and controls in somatosensory regions during wakefulness, and occipital regions during sleep. Intra-hemispheric thalamic FC was significantly higher in patients than controls following sleep onset, and disorder-dependent alterations to FC were seen in several thalamic regions always involving somatomotor and occipital regions. As interactions between thalamic sub-regions are indirect and mediated by the inhibitory thalamic reticular nucleus (TRN), the results suggest abnormal TRN function in patients with IGE, with a regional distribution which could suggest a link with the thalamocortical networks involved in the generation of alpha rhythms. Intra-thalamic FC could be a more widely applicable marker beyond patients with IGE.

journal_name

Neuroimage Clin

journal_title

NeuroImage. Clinical

authors

Bagshaw AP,Hale JR,Campos BM,Rollings DT,Wilson RS,Alvim MKM,Coan AC,Cendes F

doi

10.1016/j.nicl.2017.07.008

subject

Has Abstract

pub_date

2017-07-12 00:00:00

pages

52-57

issn

2213-1582

pii

S2213-1582(17)30174-2

journal_volume

16

pub_type

杂志文章

相关文献

NeuroImage-Clinical文献大全
  • DTI detects water diffusion abnormalities in the thalamus that correlate with an extremity pain episode in a patient with multiple sclerosis.

    abstract：BACKGROUND:Various types of multiple sclerosis (MS) related pain have been discussed. One concept is that deafferentation secondary to lesions in the spino-thalamo-cortical network can cause central pain. However, this hypothesis is somehow limited by a lack of a robust association between pain episodes and sites of le...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2013.01.008

    authors： Deppe M,Müller D,Kugel H,Ruck T,Wiendl H,Meuth SG

    更新日期：2013-01-28 00:00:00

  • Neurocognitive and neuroanatomical maturation in the clinical high-risk states for psychosis: A pattern recognition study.

    abstract：BACKGROUND:Findings from neurodevelopmental studies indicate that adolescents with psychosis spectrum disorders have delayed neurocognitive performance relative to the maturational state of their healthy peers. Using machine learning, we generated a model of neurocognitive age in healthy adults and investigated whether...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.101624

    authors： Kambeitz-Ilankovic L,Haas SS,Meisenzahl E,Dwyer DB,Weiske J,Peters H,Möller HJ,Falkai P,Koutsouleris N

    更新日期：2019-01-01 00:00:00

  • Segregating sustained attention from response inhibition in ADHD: An fMRI study.

    abstract：BACKGROUND:The functional significance of the impairment shown by patients with ADHD on response inhibition tasks is unclear. Dysfunctional behavioral and BOLD responses to rare no-go cues might reflect disruption of response inhibition (mediating withholding the response) or selective attention (identifying the rare c...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101677

    authors： Hwang S,Meffert H,Parsley I,Tyler PM,Erway AK,Botkin ML,Pope K,Blair RJR

    更新日期：2019-01-01 00:00:00

  • The relative importance of imaging markers for the prediction of Alzheimer's disease dementia in mild cognitive impairment - Beyond classical regression.

    abstract：:Selecting a set of relevant markers to predict conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) has become a challenging task given the wealth of regional pathologic information that can be extracted from multimodal imaging data. Here, we used regularized regression approaches with an elasti...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.05.006

    authors： Teipel SJ,Kurth J,Krause B,Grothe MJ,Alzheimer's Disease Neuroimaging Initiative.

    更新日期：2015-05-21 00:00:00

  • Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography.

    abstract：BACKGROUND:Diffusion imaging tractography is increasingly used to trace critical fiber tracts in brain tumor patients to reduce the risk of post-operative neurological deficit. However, the effects of peritumoral edema pose a challenge to conventional tractography using the standard diffusion tensor model. The aim of t...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.03.009

    authors： Chen Z,Tie Y,Olubiyi O,Rigolo L,Mehrtash A,Norton I,Pasternak O,Rathi Y,Golby AJ,O'Donnell LJ

    更新日期：2015-03-20 00:00:00

  • Brain network disintegration as a final common pathway for delirium: a systematic review and qualitative meta-analysis.

    abstract：:Delirium is an acute neuropsychiatric syndrome characterized by altered levels of attention and awareness with cognitive deficits. It is most prevalent in elderly hospitalized patients and related to poor outcomes. Predisposing risk factors, such as older age, determine the baseline vulnerability for delirium, while p...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.nicl.2019.101809

    authors： van Montfort SJT,van Dellen E,Stam CJ,Ahmad AH,Mentink LJ,Kraan CW,Zalesky A,Slooter AJC

    更新日期：2019-01-01 00:00:00

  • Detection of volume loss in hippocampal layers in Alzheimer's disease using 7 T MRI: a feasibility study.

    abstract：:In Alzheimer's disease (AD), the hippocampus is an early site of tau pathology and neurodegeneration. Histological studies have shown that lesions are not uniformly distributed within the hippocampus. Moreover, alterations of different hippocampal layers may reflect distinct pathological processes. 7 T MRI dramaticall...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2014.07.011

    authors： Boutet C,Chupin M,Lehéricy S,Marrakchi-Kacem L,Epelbaum S,Poupon C,Wiggins C,Vignaud A,Hasboun D,Defontaines B,Hanon O,Dubois B,Sarazin M,Hertz-Pannier L,Colliot O

    更新日期：2014-07-31 00:00:00

  • Altered intrahemispheric structural connectivity in Gilles de la Tourette syndrome.

    abstract：:Gilles de la Tourette syndrome (GTS) is a common developmental neuropsychiatric disorder characterized by tics and frequent psychiatric comorbidities, often causing significant disability. Tic generation has been linked to disturbed networks of brain areas involved in planning, controlling and execution of actions, pa...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2013.11.011

    authors： Cheng B,Braass H,Ganos C,Treszl A,Biermann-Ruben K,Hummel FC,Müller-Vahl K,Schnitzler A,Gerloff C,Münchau A,Thomalla G

    更新日期：2013-12-07 00:00:00

  • Delineation of the visual pathway in paediatric optic pathway glioma patients using probabilistic tractography, and correlations with visual acuity.

    abstract：Background:Radiological biomarkers which correlate with visual function are needed to improve the clinical management of optic pathway glioma (OPG) patients. Currently, these are not available using conventional magnetic resonance imaging (MRI) sequences. The aim of this study was to determine whether diffusion MRI cou...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2017.10.010

    authors： Hales PW,Smith V,Dhanoa-Hayre D,O'Hare P,Mankad K,d'Arco F,Cooper J,Kaur R,Phipps K,Bowman R,Hargrave D,Clark C

    更新日期：2017-10-11 00:00:00

  • Using concurrent EEG and fMRI to probe the state of the brain in schizophrenia.

    abstract：:Perceptional abnormalities in schizophrenia are associated with hallucinations and delusions, but also with negative symptoms and poor functional outcome. Perception can be studied using EEG-derived event related potentials (ERPs). Because of their excellent temporal resolution, ERPs have been used to ask when percept...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2016.08.009

    authors： Ford JM,Roach BJ,Palzes VA,Mathalon DH

    更新日期：2016-08-10 00:00:00

  • Fatigue in Gulf War Illness is associated with tonically high activation in the executive control network.

    abstract：:Gulf War Illness (GWI) is a chronic, multi-symptom illness that affects approximately 25% of Gulf veterans, with cognitive fatigue as one of its primary symptoms. Here, we investigated the neural networks associated with cognitive fatigue in GWI by asking 35 veterans with GWI and 25 healthy control subjects to perform...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.101641

    authors： Wylie GR,Genova H,Dobryakova E,DeLuca J,Chiaravalloti N,Falvo M,Cook D

    更新日期：2019-01-01 00:00:00

  • Predictors of neurofeedback training outcome: A systematic review.

    abstract：:Neurofeedback (NF), a training tool aimed at enhancing neural self-regulation, has been suggested as a complementary treatment option for neuropsychiatric disorders. Despite its potential as a neurobiological intervention directly targeting neural alterations underlying clinical symptoms, the efficacy of NF for the tr...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2020.102301

    authors： Weber LA,Ethofer T,Ehlis AC

    更新日期：2020-01-01 00:00:00

  • Hippocampal volume correlates with attenuated negative psychotic symptoms irrespective of antidepressant medication.

    abstract：BACKGROUND:Individuals with at-risk mental state for psychosis (ARMS) often suffer from depressive and anxiety symptoms, which are clinically similar to the negative symptomatology described for psychosis. Thus, many ARMS individuals are already being treated with antidepressant medication. OBJECTIVES:To investigate c...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.04.016

    authors： Bernasconi R,Smieskova R,Schmidt A,Harrisberger F,Raschle NM,Lenz C,Walter A,Simon A,Riecher-Rössler A,Radue EW,Lang UE,Fusar-Poli P,Borgwardt SJ

    更新日期：2015-04-29 00:00:00

  • The diffeomorphometry of temporal lobe structures in preclinical Alzheimer's disease.

    abstract：:This paper examines morphometry of MRI biomarkers derived from the network of temporal lobe structures including the amygdala, entorhinal cortex and hippocampus in subjects with preclinical Alzheimer's disease (AD). Based on template-centered population analysis, it is demonstrated that the structural markers of the a...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2013.09.001

    authors： Miller MI,Younes L,Ratnanather JT,Brown T,Trinh H,Postell E,Lee DS,Wang MC,Mori S,O'Brien R,Albert M,BIOCARD Research Team.

    更新日期：2013-09-16 00:00:00

  • Functional and structural changes in the brain associated with the increase in muscle sympathetic nerve activity in obstructive sleep apnoea.

    abstract：:Muscle sympathetic nerve activity (MSNA) is greatly elevated in patients with obstructive sleep apnoea (OSA) during daytime wakefulness, leading to hypertension, but the underlying mechanisms are poorly understood. By recording MSNA concurrently with functional Magnetic Resonance Imaging (fMRI) of the brain we aimed t...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2014.08.021

    authors： Fatouleh RH,Hammam E,Lundblad LC,Macey PM,McKenzie DK,Henderson LA,Macefield VG

    更新日期：2014-08-27 00:00:00

  • Decreased peak alpha frequency and impaired visual evoked potentials in first episode psychosis.

    abstract：:Abnormal spontaneous and evoked oscillations have been reported in several studies of patients with psychotic disorders. Resting alpha power and peak alpha frequency may be decreased in patients with psychosis. We used high-density EEG (hd-EEG) to record resting-state data and steady-state visual evoked potentials (SS...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101693

    authors： Murphy M,Öngür D

    更新日期：2019-01-01 00:00:00

  • Reduced binding of Pittsburgh Compound-B in areas of white matter hyperintensities.

    abstract：:The amyloid imaging agent, Pittsburgh Compound-B, binds with high affinity to β-amyloid (Aβ) in the brain, and it is well established that PiB also shows non-specific retention in white matter (WM). However, little is known about retention of PiB in areas of white matter hyperintensities (WMH), abnormalities commonly ...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.09.009

    authors： Goodheart AE,Tamburo E,Minhas D,Aizenstein HJ,McDade E,Snitz BE,Price JC,Mathis CA,Lopez OL,Klunk WE,Cohen AD

    更新日期：2015-09-29 00:00:00

  • Impact of chronic migraine attacks and their severity on the endogenous μ-opioid neurotransmission in the limbic system.

    abstract：OBJECTIVE:To evaluate, in vivo, the impact of ongoing chronic migraine (CM) attacks on the endogenous μ-opioid neurotransmission. BACKGROUND:CM is associated with cognitive-emotional dysfunction. CM is commonly associated with frequent acute medication use, including opioids. METHODS:We scanned 15 migraine patients d...

    journal_title：NeuroImage. Clinical

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.nicl.2019.101905

    authors： Jassar H,Nascimento TD,Kaciroti N,DosSantos MF,Danciu T,Koeppe RA,Smith YR,Bigal ME,Porreca F,Casey KL,Zubieta JK,DaSilva AF

    更新日期：2019-01-01 00:00:00

  • Diffusion tensor imaging of nigral degeneration in Parkinson's disease: A region-of-interest and voxel-based study at 3 T and systematic review with meta-analysis.

    abstract：:There is increasing interest in developing a reliable, affordable and accessible disease biomarker of Parkinson's disease (PD) to facilitate disease modifying PD-trials. Imaging biomarkers using magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) can describe parameters such as fractional anisotropy (F...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2013.10.006

    authors： Schwarz ST,Abaei M,Gontu V,Morgan PS,Bajaj N,Auer DP

    更新日期：2013-10-14 00:00:00

  • White matter integrity in small vessel disease is related to cognition.

    abstract：:Cerebral small vessel disease, including white matter hyperintensities (WMH) and lacunes of presumed vascular origin, is common in elderly people and is related to cognitive impairment and dementia. One possible mechanism could be the disruption of white matter tracts (both within WMH and normal-appearing white matter...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.02.003

    authors： Tuladhar AM,van Norden AG,de Laat KF,Zwiers MP,van Dijk EJ,Norris DG,de Leeuw FE

    更新日期：2015-02-16 00:00:00

  • Changes in brain perfusion in successive arterial spin labeling MRI scans in neonates with hypoxic-ischemic encephalopathy.

    abstract：:The primary objective of this study was to evaluate changes in cerebral blood flow (CBF) using arterial spin labeling MRI between day 4 of life (DOL4) and day 11 of life (DOL11) in neonates with hypoxic-ischemic encephalopathy (HIE) treated with hypothermia. The secondary objectives were to compare CBF values between ...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101939

    authors： Proisy M,Corouge I,Legouhy A,Nicolas A,Charon V,Mazille N,Leroux S,Bruneau B,Barillot C,Ferré JC

    更新日期：2019-01-01 00:00:00

  • Ultra-high-field sodium MRI as biomarker for tumor extent, grade and IDH mutation status in glioma patients.

    abstract：PURPOSE:This prospective clinical trial investigated sodium (23Na) MRI at 7 Tesla (T) field strength as biomarker for tumor extent, isocitrate dehydrogenase (IDH) mutation and O6-methylguanine DNA methyltransferase (MGMT) promotor methylation in glioma patients. METHODS:28 glioma patients underwent 23Na MRI on a 7T sc...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2020.102427

    authors： Regnery S,Behl NGR,Platt T,Weinfurtner N,Windisch P,Deike-Hofmann K,Sahm F,Bendszus M,Debus J,Ladd ME,Schlemmer HP,Rieken S,Adeberg S,Paech D

    更新日期：2020-01-01 00:00:00

  • Selection bias in the reported performances of AD classification pipelines.

    abstract：:The last decade has seen a great proliferation of supervised learning pipelines for individual diagnosis and prognosis in Alzheimer's disease. As more pipelines are developed and evaluated in the search for greater performance, only those results that are relatively impressive will be selected for publication. We pres...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2016.12.018

    authors： Mendelson AF,Zuluaga MA,Lorenzi M,Hutton BF,Ourselin S,Alzheimer's Disease Neuroimaging Initiative.

    更新日期：2016-12-24 00:00:00

  • MEG-based detection and localization of perilesional dysfunction in chronic stroke.

    abstract：:Post-stroke impairment is associated not only with structural lesions, but also with dysfunction in surviving perilesional tissue. Previous studies using equivalent current dipole source localization of MEG/EEG signals have demonstrated a preponderance of slow-wave activity localized to perilesional areas. Recent stud...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.03.019

    authors： Chu RK,Braun AR,Meltzer JA

    更新日期：2015-04-08 00:00:00

  • Assessment of longitudinal hippocampal atrophy in the first year after ischemic stroke using automatic segmentation techniques.

    abstract：:We assessed first-year hippocampal atrophy in stroke patients and healthy controls using manual and automated segmentations: AdaBoost, FIRST (fsl/v5.0.8), FreeSurfer/v5.3 and v6.0, and Subfields (in FreeSurfer/v6.0). We estimated hippocampal volumes in 39 healthy controls and 124 stroke participants at three months, a...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.102008

    authors： Khlif MS,Werden E,Egorova N,Boccardi M,Redolfi A,Bird L,Brodtmann A

    更新日期：2019-01-01 00:00:00

  • Brain responses to vestibular pain and its anticipation in women with Genito-Pelvic Pain/Penetration Disorder.

    abstract：OBJECTIVE:In DSM-5, pain-related fear during anticipation of vaginal penetration is a diagnostic criterion of Genito-Pelvic Pain/Penetration Disorder (GPPPD). We aimed to investigate subjective and brain responses during anticipatory fear and subsequent induction of vestibular pain in women with GPPPD. METHODS:Women w...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2017.07.017

    authors： Pazmany E,Ly HG,Aerts L,Kano M,Bergeron S,Verhaeghe J,Peeters R,Tack J,Dupont P,Enzlin P,Van Oudenhove L

    更新日期：2017-07-25 00:00:00

  • Disrupted functional connectivity in primary progressive apraxia of speech.

    abstract：:Apraxia of speech is a motor speech disorder thought to result from impaired planning or programming of articulatory movements. It can be the initial or only manifestation of a degenerative disease, termed primary progressive apraxia of speech (PPAOS). The aim of this study was to use task-free functional magnetic res...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2018.02.036

    authors： Botha H,Utianski RL,Whitwell JL,Duffy JR,Clark HM,Strand EA,Machulda MM,Tosakulwong N,Knopman DS,Petersen RC,Jack CR Jr,Josephs KA,Jones DT

    更新日期：2018-03-03 00:00:00

  • Injury to white matter tracts in relapsing-remitting multiple sclerosis: A possible therapeutic window within the first 5 years from onset using diffusion-tensor imaging tract-based spatial statistics.

    abstract：:DTI studies in multiple sclerosis (MS) reveal white matter (WM) injury that occurs with disease progression. In the present study we aimed to elucidate the relationship of microstructural WM damage in patients with varying periods of disease duration. DTI scans were acquired from 90 MS patients and 25 healthy controls...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2015.04.020

    authors： Asaf A,Evan S,Anat A

    更新日期：2015-04-30 00:00:00

  • Psychopathy is associated with shifts in the organization of neural networks in a large incarcerated male sample.

    abstract：:Psychopathy is a personality disorder defined by antisocial behavior paired with callousness, low empathy, and low interpersonal emotions. Psychopathic individuals reliably display complex atypicalities in emotion and attention processing that are evident when examining task performance, activation within specific neu...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.102083

    authors： Tillem S,Harenski K,Harenski C,Decety J,Kosson D,Kiehl KA,Baskin-Sommers A

    更新日期：2019-01-01 00:00:00

  • Brain connectivity tracks effects of chemotherapy separately from behavioral measures.

    abstract：:Several studies in cancer research have suggested that cognitive dysfunction following chemotherapy, referred to in lay terms as "chemobrain", is a serious problem. At present, the changes in integrative brain function that underlie such dysfunction remain poorly understood. Recent developments in neuroimaging suggest...

    journal_title：NeuroImage. Clinical

    pub_type： 杂志文章

    doi：10.1016/j.nicl.2019.101654

    authors： Kardan O,Reuter-Lorenz PA,Peltier S,Churchill NW,Misic B,Askren MK,Jung MS,Cimprich B,Berman MG

    更新日期：2019-01-01 00:00:00