Abstract:
BACKGROUND:Describing vitamin D status and its predictors in various populations is important in order to target public health measures. OBJECTIVES:To describe the status and predictors of vitamin D status in healthy Nepalese mothers and infants. METHODS:500 randomly selected Nepalese mother and infant pairs were included in a cross-sectional study. Plasma 25(OH)D concentrations were measured by LC-MS/MS and multiple linear regression analyses were used to identify predictors of vitamin D status. RESULTS:Among the infants, the prevalence of vitamin D insufficiency (25(OH)D <50 nmol/L) and deficiency (<30 nmol/L) were 3.6% and 0.6%, respectively, in contrast to 59.8% and 14.0% among their mothers. Infant 25(OH)D concentrations were negatively associated with infant age and positively associated with maternal vitamin D status and body mass index (BMI), explaining 22% of the variability in 25(OH)D concentration. Global solar radiation, maternal age and BMI predicted maternal 25(OH)D concentration, explaining 9.7% of its variability. CONCLUSION:Age and maternal vitamin D status are the main predictors of vitamin D status in infants in Bhaktapur, Nepal, who have adequate vitamin D status despite poor vitamin D status in their mothers.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Haugen J,Ulak M,Chandyo RK,Henjum S,Thorne-Lyman AL,Ueland PM,Midtun Ø,Shrestha PS,Strand TAdoi
10.3390/nu8120825subject
Has Abstractpub_date
2016-12-21 00:00:00issue
12issn
2072-6643pii
nu8120825journal_volume
8pub_type
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