Abstract:
:Cognitive impairment is strongly associated with functional outcomes in psychiatric patients. Involvement of n-3 long chain polyunsaturated fatty acid (n-3 LC-PUFA), in particular docosahexaenoic acid (DHA), in brain functions is largely documented. DHA is incorporated into membrane phospholipids as structural component, especially in the central nervous system where it also has important functional effects. The aim of this review is to investigate the relationship between DHA and cognitive function in relation to mental disorders. Results from few randomized controlled trials (RCTs) on the effects of DHA (alone or in combination) in psychotic, mood and neurodevelopmental disorders, respectively, suggest that no conclusive remarks can be drawn.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Ciappolino V,Mazzocchi A,Botturi A,Turolo S,Delvecchio G,Agostoni C,Brambilla Pdoi
10.3390/nu11040769subject
Has Abstractpub_date
2019-04-02 00:00:00issue
4issn
2072-6643pii
nu11040769journal_volume
11pub_type
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