Epigenetics: spotlight on type 2 diabetes and obesity.

abstract：:N-Methyl-D-Aspartate(NMDA)-sensitive glutamate receptors, are critically involved in the induction of the learning process. Activation of NMDA receptors by glutamate lead to massive influx of extracellular Ca2+, with ensuing activation of a variety of Ca(2+)-dependent enzymes, including protein kinase C. This triggers...

journal_title：Journal of endocrinological investigation

authors： Caruso S,Agnello C,Campo MG,Nicoletti F

更新日期：1993-12-01 00:00:00

abstract：:Pegvisomant, a GH receptor antagonist, is a new pharmaceutical approach to acromegaly. It enables IGF-I levels to return in the age- and sex-reference range in approximately 90% of patients. This new approach is particularly beneficial in those patients who do not experience control of hormone hypersecretion after sur...

journal_title：Journal of endocrinological investigation

authors： Colao A,Pivonello R,Cappabianca P,Auriemma RS,De Martino MC,Ciccarelli A,de Divitiis E,Lombardi G

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND/AIMS:Aldosterone and the mineralocorticoid receptor (MR) play a major role in sodium balance and blood pressure control. They are also involved in adipocyte metabolism. The aim of this study was to analyze the association between the MR p.I180V polymorphism with hypertension and markers of cardiovascular ris...

journal_title：Journal of endocrinological investigation

authors： Fernandes-Rosa FL,Bueno AC,de Souza RM,de Castro M,dos Santos JE,Foss MC,Zennaro MC,Bettiol H,Barbieri MA,Antonini SR

更新日期：2010-07-01 00:00:00

abstract：:Liquid-chromatography - tandem mass spectrometry (LC-MS/MS) is becoming the method of choice for clinical steroid analysis. In most instances, it has the advantage of higher sensitivity, better reproducibility and greater specificity than commercial immunoassay techniques. The method requires only minimal sample prepa...

journal_title：Journal of endocrinological investigation

authors： Kulle AE,Welzel M,Holterhus PM,Riepe FG

更新日期：2011-10-01 00:00:00

abstract：:Erectile dysfunction (ED) increases in prevalence and severity because of aging processes and related organic, iatrogenic and social problems. Decline of testosterone (T) levels is observed with age and also in illnesses with a common basis of endothelial damage. The T deficiency may lead to decreased energy, mood dep...

journal_title：Journal of endocrinological investigation

authors： Frajese GV,Pozzi F

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To investigate the inflammatory markers in polycystic ovary syndrome (PCOS) and associations of these markers with obesity and in vitro fertilization (IVF) outcomes. METHODS:A total of 292 women underwent IVF procedure either with PCOS (n = 146) or without PCOS (n = 146, age, and body mass index (BMI) matche...

journal_title：Journal of endocrinological investigation

authors： Çakıroğlu Y,Vural F,Vural B

更新日期：2016-08-01 00:00:00

abstract：:1-123 metaiodobenzylguanidine (1-123 MIBG) scintigraphy is known for its high specificity in detecting pheochromocytoma and other tumors of neural crest origin. In this rare case report, we describe a definite adrenocortical adenoma that demonstrated false-positive uptake at I-123 MIBG scintigraphy and a remarkable ac...

journal_title：Journal of endocrinological investigation

authors： Letizia C,De Toma G,Massa R,Corsi A,Caliumi C,Subioli S,D'Erasmo E

更新日期：1998-12-01 00:00:00

abstract：:Ketoacidosis is a metabolic alteration caused by absolute or relative insulin deficiency and oversecretion of glucagon. Prompt diagnosis and rapid initiation of treatment are mandatory to avoid the complications and fatal outcome. Reduction of plasma glucose to levels within acceptable limits, block of ketogenesis, re...

journal_title：Journal of endocrinological investigation

authors： Reitano G

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Adipose tissue has been suggested to influence bone density and metabolism through the effect of some adipokines. However, whether adiponectin and visfatin may correlate with bone metabolism is still unclear. AIM:The aim of this study was to investigate the relationship of adiponectin and visfatin with bone...

journal_title：Journal of endocrinological investigation

authors： Iacobellis G,Iorio M,Napoli N,Cotesta D,Zinnamosca L,Marinelli C,Petramala L,Minisola S,D'Erasmo E,Letizia C

更新日期：2011-01-01 00:00:00

abstract：:Prolactin, LH and FSH circadian secretion were studied in a group of 20 boys in various pubertal stages and in 13 normal male adults. Prolactin 24-hour integrated concentration was similar in all groups except in stage 2 boys, in which it was significantly higher with respect to stage 3-4 boys. This pattern was observ...

journal_title：Journal of endocrinological investigation

authors： Minuto F,Barreca A,Ferrini S,Del Monte P,Bernasconi D,Giordano G

更新日期：1984-06-01 00:00:00

abstract：:Seventy years after the first successful radioiodine treatment of metastatic differentiated thyroid cancer (DTC), radioiodine (131I) therapy for this type of tumor is still without alternative. During the last decade, some key issues such as individual dosimetry, and preparation of 131I therapy by recombinant human TS...

journal_title：Journal of endocrinological investigation

authors： Luster M,Hänscheid H,Freudenberg LS,Verburg FA

更新日期：2012-01-01 00:00:00

abstract：:The aim of this study was to investigate the effects of age, duration of diabetes, sex and ICA (Islet cell cytoplasmic antibody) on beta-cell reserves and to develop a model within the first 2 years of Type 1 diabetes. Beta-cell reserve is evaluated as fasting (FCp) and 1 mg i.v. glucagon stimulated C-peptide (SCp) le...

journal_title：Journal of endocrinological investigation

authors： Altuntas Y

更新日期：2002-12-01 00:00:00

abstract：:Severe bleeding into the peritoneal cavity from a ruptured ovulatory follicle is a rare complication in women receiving anticoagulation therapy. A number of both surgical and non surgical methods have been proposed to solve this problem. We adopted a novel therapeutic approach in a 40-year old patient who presented wi...

journal_title：Journal of endocrinological investigation

authors： Ulrich U,Rossmanith WG

更新日期：1994-05-01 00:00:00

abstract：:The underlying mechanism leading to carcinogenesis involves genomic instability, likely related to aneuploidy. While p53 as a "guardian of the genome" is an appealing candidate as an initiator of genomic instability, its mutations or deletions usually occur late in the course of tumor progression. P53 may, however, be...

journal_title：Journal of endocrinological investigation

authors： Farid NR

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:Globalisation has extended to the kitchen and the Asian cuisine has gained international popularity with sushi and seaweed now being widespread. We explored the possible acute adverse effects of an iodine load from a single sushi-and-seaweed meal as seaweed iodine may induce thyroid dysfunction. METHODS:Nine...

journal_title：Journal of endocrinological investigation

authors： Noahsen P,Kleist I,Larsen HM,Andersen S

更新日期：2020-04-01 00:00:00

abstract：:A rapid routine method of determining estrogens in non-pregnancy urine is described. It involves the following steps: 1) Dilution of each urine sample with an equal volume of saturated ammonium sulfate solution; 2) Addition of Sephadex G-15 beads; 3) Filtration of the mixture; 4) Liberation of the estrogens from the S...

journal_title：Journal of endocrinological investigation

authors： Gebhardt DO,Soederhuizen W,Moolenaar AJ

更新日期：1978-04-01 00:00:00

abstract：:The authors report the results of a correlation study between the direct Immunobead Test (d-IBT) and other techniques for antisperm antibodies detection. The Gelatin Agglutination Test (GAT) and Tray Agglutination Test (TAT) were used to detect antibodies in blood serum and seminal plasma ("indirect methods"). The Dir...

journal_title：Journal of endocrinological investigation

authors： Dondero F,Lenzi A,Gandini L,Lombardo F,Culasso F

更新日期：1991-06-01 00:00:00

abstract：:A 33-year-old female presented in 1966 with striking pigmentation, typical of Addison's disease, and amenorrhea. Endocrine assessment then showed normal basal serum cortisol and urinary hydroxysteroid levels, but serum cortisol did not respond to stimulation with either exogenous ACTH or lysine vasopressin. Steroid re...

journal_title：Journal of endocrinological investigation

authors： Whitehead EM,Atkinson AB,Hadden DR,Weaver J,Sheridan B

更新日期：1989-03-01 00:00:00

abstract：:Pyridinoline (Pyr) and deoxypyridinoline (D-Pyr) are two cross-links of collagen molecules, that are present in the extracellular matrix and released during its degradation. Pyr is present in bone and cartilage, but not in significant amounts in other connective tissues and D-Pyr appears to be specific for bone tissue...

journal_title：Journal of endocrinological investigation

authors： Calabresi E,Lasagni L,Franceschelli F,de Leonardis V,Becorpi A,Serio M,Brandi ML

更新日期：1994-09-01 00:00:00

abstract：:Thyrocytes from normal and goitrous portions of the thyroid gland from a patient with an enormous (635 gm) goiter were cultured in media, and their relative abilities to uptake thymidine, synthesize DNA, and secrete Tg and T4 were assessed. Tg, T4 and the ratio Tg/T4 in media at 72 h were 120 micrograms/dl, 1.6 microg...

journal_title：Journal of endocrinological investigation

authors： Tseng YC,Burman KD,Baker JR Jr,D'Avis J,Wartofsky L

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:The aim of the current study was to evaluate the association of osteoprotegerin and vascular endothelial growth factor (VEGF) with glycemic indices and diabetes status. METHODS:A total of 44 normoalbuminuric Type 1 diabetic patients and 44 healthy control subjects, matched for age, body mass index, sex rati...

journal_title：Journal of endocrinological investigation

authors： Esteghamati A,Arefzadeh A,Zandieh A,Salehi Sadaghiani M,Noshad S,Nakhjavani M

更新日期：2013-07-01 00:00:00

abstract：:The aim of acromegaly treatment is to control the disease by suppressing GH hyperactivity and reducing the size or impeding the growth of the pituitary GH secreting mass. Over recent years, many studies have emphasized the role of SS analogs in the treatment of acromegaly. In fact, SS analogs have been demonstrated to...

journal_title：Journal of endocrinological investigation

authors： Gola M,Bonadonna S,Mazziotti G,Amato G,Giustina A

更新日期：2006-01-01 00:00:00

abstract：:The effect of right- and left-sided intra-amygdaloid injection of kainic acid on the hypothalamo-hypophyseal-testicular axis was studied in rats. Both right- and left-sided injection of the neurotoxin into the amygdala resulted in a significant decrease in basal testosterone secretion in vitro of both testes and in se...

journal_title：Journal of endocrinological investigation

authors： Banczerowski P,Csaba Z,Csernus V,Gerendai I

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS) are well-recognized complications of obesity. This study was designed to evaluate the role of the UCP1 -3826 A>G polymorphism, adiponectin levels, leptin/adiponectin ratio (L/A), and main biochemical parameters in 102 unrelated se...

journal_title：Journal of endocrinological investigation

authors： Labruna G,Pasanisi F,Nardelli C,Tarantino G,Vitale DF,Bracale R,Finelli C,Genua MP,Contaldo F,Sacchetti L

更新日期：2009-06-01 00:00:00

abstract：:In mild glucose intolerance plasma concentration of C-peptide seems to give an estimate of pancreatic B cell secretion more reliable than plasma insulin itself. In the present study we measured the plasma levels of insulin and C-peptide after oral glucose load in 100 mildly glucose intolerant subjects, focusing our at...

journal_title：Journal of endocrinological investigation

authors： Bonora E,Zavaroni I,Manicardi V,Coscelli C,Butturini U

更新日期：1986-10-01 00:00:00

abstract：:Iodine balance during pregnancy and lactation was investigated by measuring iodine concentration in the urine of 11 pregnant women, born and living in a moderately iodine deficient endemic goiter area in Northeastern Sicily, collected during the last week of pregnancy, and between the 5th and 7th day after delivery, a...

journal_title：Journal of endocrinological investigation

authors： Vermiglio F,Lo Presti VP,Finocchiaro MD,Battiato S,Grasso L,Ardita FV,Mancuso A,Trimarchi F

更新日期：1992-02-01 00:00:00

abstract：PURPOSE:Post-finasteride syndrome (PFS) has been reported in a subset of patients treated with finasteride (an inhibitor of the enzyme 5alpha-reductase) for androgenetic alopecia. These patients showed, despite the suspension of the treatment, a variety of persistent symptoms, like sexual dysfunction and cognitive and ...

journal_title：Journal of endocrinological investigation

authors： Borgo F,Macandog AD,Diviccaro S,Falvo E,Giatti S,Cavaletti G,Melcangi RC

更新日期：2020-09-19 00:00:00

abstract：:Unfortunately, the fourth author's middle name was missed out in the original publication of this article. The complete correct name should read as follows. ...

journal_title：Journal of endocrinological investigation

authors： Tresoldi AS,Sburlati LF,Rodari M,Schinkelshoek MS,Perrino M,De Leo S,Montefusco L,Colombo P,Arosio M,Lania AGA,Fugazzola L,Chiti A

更新日期：2018-08-01 00:00:00

abstract：:Human gonadotropins are widely used for induction of ovulation in the treatment of anovulatory infertility and for induction of multiple follicular development (MFD) in in vitro fertilization (IVF), gamete intrafallopian transfer (GIFT), and artificial insemination with husband's semen (AIH) programs. Reported is a pa...

journal_title：Journal of endocrinological investigation

authors： Mais V,Melis GB,Antinori D,Paoletti AM,Strigini F,Guerriero S,de Ruggiero A,Fioretti P

更新日期：1990-10-01 00:00:00

abstract：:The unlimited availability of GH obtained by recombinant DNA technology has allowed optimization of treatment in GH-deficient (GHD) children. At the same time it has prompted a number of studies in conditions not characterized by GHD such as Turner syndrome, intrauterine growth retardation, chronic renal failure and o...

journal_title：Journal of endocrinological investigation

authors： Loche S,Casini MR,Ubertini GM,Cappa M

更新日期：2005-02-01 00:00:00