当前位置： SCI文献检索 > Nutrients期刊下所有文献 > The Potential Protective Effects of Polyphenols in Asbestos-Mediated Inflammation and Carcinogenesis of Mesothelium.

The Potential Protective Effects of Polyphenols in Asbestos-Mediated Inflammation and Carcinogenesis of Mesothelium.

Abstract：

:Malignant Mesothelioma (MM) is a tumor of the serous membranes linked to exposure to asbestos. A chronic inflammatory response orchestrated by mesothelial cells contributes to the development and progression of MM. The evidence that: (a) multiple signaling pathways are aberrantly activated in MM cells; (b) asbestos mediated-chronic inflammation has a key role in MM carcinogenesis; (c) the deregulation of the immune system might favor the development of MM; and (d) a drug might have a better efficacy when injected into a serous cavity thus bypassing biotransformation and reaching an effective dose has prompted investigations to evaluate the effects of polyphenols for the therapy and prevention of MM. Dietary polyphenols are able to inhibit cancer cell growth by targeting multiple signaling pathways, reducing inflammation, and modulating immune response. The ability of polyphenols to modulate the production of pro-inflammatory molecules by targeting signaling pathways or ROS might represent a key mechanism to prevent and/or to contrast the development of MM. In this review, we will report the current knowledge on the ability of polyphenols to modulate the immune system and production of mediators of inflammation, thus revealing an important tool in preventing and/or counteracting the growth of MM.

journal_name

Nutrients

journal_title

Nutrients

authors

Benvenuto M,Mattera R,Taffera G,Giganti MG,Lido P,Masuelli L,Modesti A,Bei R

doi

10.3390/nu8050275

subject

Has Abstract

pub_date

2016-05-09 00:00:00

issue

5

issn

2072-6643

pii

nu8050275

journal_volume

8

pub_type

杂志文章,评审

相关文献

Nutrients文献大全
  • Soy, Soy Foods and Their Role in Vegetarian Diets.

    abstract：:Soy is a basic food ingredient of traditional Asian cuisine used for thousands of years. In Western countries, soybeans have been introduced about a hundred years ago and recently they are mainly used for surrogate foods production. Soy and soy foods are common nutritional solutions for vegetarians, due to their high ...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu10010043

    authors： Rizzo G,Baroni L

    更新日期：2018-01-05 00:00:00

  • The Pattern of Complementary Foods in American Infants and Children Aged 0⁻5 Years Old-A Cross-Sectional Analysis of Data from the NHANES 2011⁻2014.

    abstract：:Proper nutrition early in life can influence children’s present and future health. While several authoritative sources provide eating/food recommendations, only a few studies have assessed whether these recommendations are followed. The goal of this paper was to examine food and nutrient intakes on any given day...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu10070827

    authors： Demmer E,Cifelli CJ,Houchins JA,Fulgoni VL 3rd

    更新日期：2018-06-26 00:00:00

  • A Potential Tool for Clinicians; Evaluating a Computer-Led Dietary Assessment Method in Overweight and Obese Women during Weight Loss.

    abstract：:Many Americans are attempting to lose weight with the help of healthcare professionals. Clinicians can improve weight loss results by using technology. Accurate dietary assessment is crucial to effective weight loss. The aim of this study was to validate a computer-led dietary assessment method in overweight/obese wom...

    journal_title：Nutrients

    pub_type： 临床试验,杂志文章

    doi：10.3390/nu9030218

    authors： Widaman AM,Keim NL,Burnett DJ,Miller B,Witbracht MG,Widaman KF,Laugero KD

    更新日期：2017-03-01 00:00:00

  • Key Vitamin D Target Genes with Functions in the Immune System.

    abstract：:The biologically active form of vitamin D3, 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3), modulates innate and adaptive immunity via genes regulated by the transcription factor vitamin D receptor (VDR). In order to identify the key vitamin D target genes involved in these processes, transcriptome-wide datasets were compare...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu12041140

    authors： Koivisto O,Hanel A,Carlberg C

    更新日期：2020-04-19 00:00:00

  • Self-Directed Weight Loss Strategies: Energy Expenditure Due to Physical Activity Is Not Increased to Achieve Intended Weight Loss.

    abstract：UNLABELLED:Reduced physical activity and almost unlimited availability of food are major contributors to the development of obesity. With the decline of strenuous work, energy expenditure due to spontaneous physical activity has attracted increasing attention. Our aim was to assess changes in energy expenditure, physic...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu7075256

    authors： Elbelt U,Schuetz T,Knoll N,Burkert S

    更新日期：2015-07-16 00:00:00

  • Reduced anxiety in forensic inpatients after a long-term intervention with Atlantic salmon.

    abstract：:The aim of the present study was to investigate the effects of Atlantic salmon consumption on underlying biological mechanisms associated with anxiety such as heart rate variability (HRV) and heart rate (HR) as well as a measure of self-reported anxiety. Moreover, these biological and self-reported outcome measures we...

    journal_title：Nutrients

    pub_type： 杂志文章,随机对照试验

    doi：10.3390/nu6125405

    authors： Hansen AL,Olson G,Dahl L,Thornton D,Grung B,Graff IE,Frøyland L,Thayer JF

    更新日期：2014-11-26 00:00:00

  • High Fat-High Fructose Diet-Induced Changes in the Gut Microbiota Associated with Dyslipidemia in Syrian Hamsters.

    abstract：:Aim: The objective of this study was to characterize the early effects of high fructose diets (with and without high fat) on both the composition of the gut microbiota and lipid metabolism in Syrian hamsters, a reproducible preclinical model of diet-induced dyslipidemia. Methods: Eight-week-old male hamsters were fed ...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu12113557

    authors： Horne RG,Yu Y,Zhang R,Abdalqadir N,Rossi L,Surette M,Sherman PM,Adeli K

    更新日期：2020-11-20 00:00:00

  • Inula Japonica Thunb. Flower Ethanol Extract Improves Obesity and Exercise Endurance in Mice Fed A High-Fat Diet.

    abstract：:Inula japonica Thunb. (Asteraceae) is a flowering plant that grows mainly in Korea, Japan, and China and its flower extract has diverse biological effects such as anti-inflammatory and antioxidative activities. However, the effects on obesity and enhancement of endurance capacity have not been explored yet. This study...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu11010017

    authors： Park SH,Lee DH,Kim MJ,Ahn J,Jang YJ,Ha TY,Jung CH

    更新日期：2018-12-20 00:00:00

  • Reducing the Burden of Anemia and Neural Tube Defects in Low- and Middle-Income Countries: An Analysis to Identify Countries with an Immediate Potential to Benefit from Large-Scale Mandatory Fortification of Wheat Flour and Rice.

    abstract：:Using a predetermined set of criteria, including burden of anemia and neural tube defects (NTDs) and an enabling environment for large-scale fortification, this paper identifies 18 low- and middle-income countries with the highest and most immediate potential for large-scale wheat flour and/or rice fortification in te...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu13010244

    authors： Kancherla V,Chadha M,Rowe L,Thompson A,Jain S,Walters D,Martinez H

    更新日期：2021-01-16 00:00:00

  • Dietary Salt Restriction in Chronic Kidney Disease: A Meta-Analysis of Randomized Clinical Trials.

    abstract：BACKGROUND:A clear evidence on the benefits of reducing salt in people with chronic kidney disease (CKD) is still lacking. Salt restriction in CKD may allow better control of blood pressure (BP) as shown in a previous systematic review while the effect on proteinuria reduction remains poorly investigated. METHODS:We p...

    journal_title：Nutrients

    pub_type： 杂志文章,meta分析,评审

    doi：10.3390/nu10060732

    authors： Garofalo C,Borrelli S,Provenzano M,De Stefano T,Vita C,Chiodini P,Minutolo R,De Nicola L,Conte G

    更新日期：2018-06-06 00:00:00

  • Effects of Three Commercially Available Sports Drinks on Substrate Metabolism and Subsequent Endurance Performance in a Postprandial State.

    abstract：:Purpose: To examine the effects of commercially available sports beverages with various components on substrate metabolism and subsequent performance. Methods: Two studies were conducted in a double-blinded, counterbalanced manner. Study I was designed to determine the glycemic index, while study II determined the uti...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu9040377

    authors： Qin L,Wang QR,Fang ZL,Wang T,Yu AQ,Zhou YJ,Zheng Y,Yi MQ

    更新日期：2017-04-12 00:00:00

  • Dietary Intake of Vitamin D from Dairy Products Reduces the Risk of Osteoporosis.

    abstract：BACKGROUND:Vitamin D and calcium are important dietary compounds that affect bone mass, even if other minerals (potassium, zinc, etc.) and vitamins (A, C and K) are also involved. Vitamin D and certain minerals, in fact, play an important role in calcium homeostasis and calcium absorption. Hip fracture incidence is hig...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu12061743

    authors： Polzonetti V,Pucciarelli S,Vincenzetti S,Polidori P

    更新日期：2020-06-10 00:00:00

  • The two-component model for calculating total body fat from body density: an evaluation in healthy women before, during and after pregnancy.

    abstract：:A possibility to assess body composition during pregnancy is often important. Estimating body density (DB) and use the two-component model (2CM) to calculate total body fat (TBF) represents an option. However, this approach has been insufficiently evaluated during pregnancy. We evaluated the 2CM, and estimated fat-fre...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu6125888

    authors： Forsum E,Henriksson P,Löf M

    更新日期：2014-12-17 00:00:00

  • Comparison of Abdominal Visceral Adipose Tissue Area Measured by Computed Tomography with That Estimated by Bioelectrical Impedance Analysis Method in Korean Subjects.

    abstract：:We evaluated the concordance between visceral fat area (VFA) estimated by bioelectrical impedance analysis (BIA) or computed tomography (CT) in Korean subjects with a wide range in age and body mass index (BMI). In 1006 individuals (mean age 55.2 ± 11.8 (19-87) years, mean BMI 26.0 ± 3.5 (17-46) kg/m², 48.9% men), VFA...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu7125548

    authors： Lee DH,Park KS,Ahn S,Ku EJ,Jung KY,Kim YJ,Kim KM,Moon JH,Choi SH,Park KS,Jang HC,Lim S

    更新日期：2015-12-16 00:00:00

  • Weight Loss and Hypertension in Obese Subjects.

    abstract：:Arterial hypertension is strongly related to overweight and obesity. In obese subjects, several mechanisms may lead to hypertension such as insulin and leptin resistance, perivascular adipose tissue dysfunction, renal impairment, renin-angiotensin-aldosterone-system activation and sympathetic nervous system activity. ...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu11071667

    authors： Fantin F,Giani A,Zoico E,Rossi AP,Mazzali G,Zamboni M

    更新日期：2019-07-21 00:00:00

  • Effects of a Voluntary Front-of-Pack Nutrition Labelling System on Packaged Food Reformulation: The Health Star Rating System in New Zealand.

    abstract：:Interpretive, front-of-pack (FOP) nutrition labels may encourage reformulation of packaged foods. We aimed to evaluate the effects of the Health Star Rating (HSR), a new voluntary interpretive FOP labelling system, on food reformulation in New Zealand. Annual surveys of packaged food and beverage labelling and composi...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu9080918

    authors： Mhurchu CN,Eyles H,Choi YH

    更新日期：2017-08-22 00:00:00

  • MADD-FOLH1 Polymorphisms and Their Haplotypes with Serum Lipid Levels and the Risk of Coronary Heart Disease and Ischemic Stroke in a Chinese Han Population.

    abstract：:This study aimed to detect the association of the MADD-FOLH1 single nucleotide polymorphisms (SNPs) and their haplotypes with the risk of coronary heart disease (CHD) and ischemic stroke (IS) in a Chinese Han population. Six SNPs of rs7395662, rs326214, rs326217, rs1051006, rs3736101, and rs7120118 were genotyped in 5...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu8040208

    authors： Wu DF,Yin RX,Cao XL,Huang F,Wu JZ,Chen WX

    更新日期：2016-04-08 00:00:00

  • The Effect of the Yingyangbao Complementary Food Supplement on the Nutritional Status of Infants and Children: A Systematic Review and Meta-Analysis.

    abstract：:Yingyangbao (YYB) is a nutrient-dense complementary food supplement for infants and young children in China. There has been considerable interest and research on the potential effects of YYB on hematological and anthropometric outcomes in China, but limited effort has been made to consolidate and synthesize the eviden...

    journal_title：Nutrients

    pub_type： 杂志文章,meta分析

    doi：10.3390/nu11102404

    authors： Li Z,Li X,Sudfeld CR,Liu Y,Tang K,Huang Y,Fawzi W

    更新日期：2019-10-08 00:00:00

  • Do Aspects of Protein Intake Vary Across the Week in Healthy Community-Dwelling Older Adults?-An enable Study.

    abstract：:Various aspects of protein intake are thought to be crucial for the prevention of sarcopenia in older adults. Information about the day-to-day variation in these aspects is lacking. Our objective was to examine whether daily protein intake, protein distribution across meals, number of meals providing adequate protein,...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu10091217

    authors： Gingrich A,Rennekamp R,Brandl B,Skurk T,Hauner H,Sieber CC,Volkert D,Kiesswetter E

    更新日期：2018-09-03 00:00:00

  • Crocin Ameliorates Atopic Dermatitis Symptoms by down Regulation of Th2 Response via Blocking of NF-κB/STAT6 Signaling Pathways in Mice.

    abstract：:Crocin, a major constituent of Gardenia jasminoides, is a natural colorant carotenoid compound that has been reported to have anti-inflammatory effects. This study investigated the therapeutic effects of crocin on mice with atopic dermatitis induced by Dermatophagoides farinae crude extract, which is a common environm...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu10111625

    authors： Sung YY,Kim HK

    更新日期：2018-11-02 00:00:00

  • Fish Oil Supplementation Reduces Inflammation but Does Not Restore Renal Function and Klotho Expression in an Adenine-Induced CKD Model.

    abstract：BACKGROUND:Chronic kidney disease and inflammation promote loss of Klotho expression. Given the well-established anti-inflammatory effects of omega-3 fatty acids, we aimed to investigate the effect of fish oil supplementation in a model of CKD. METHODS:Male C57BL/6 mice received supplementation with an adenine-enriche...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu10091283

    authors： Henao Agudelo JS,Baia LC,Ormanji MS,Santos ARP,Machado JR,Saraiva Câmara NO,Navis GJ,de Borst MH,Heilberg IP

    更新日期：2018-09-11 00:00:00

  • Current Hypothesis for the Relationship between Dietary Rice Bran Intake, the Intestinal Microbiota and Colorectal Cancer Prevention.

    abstract：:Globally, colorectal cancer (CRC) is the third most common form of cancer. The development of effective chemopreventive strategies to reduce CRC incidence is therefore of paramount importance. Over the past decade, research has indicated the potential of rice bran, a byproduct of rice milling, in CRC chemoprevention. ...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu8090569

    authors： So WK,Law BM,Law PT,Chan CW,Chair SY

    更新日期：2016-09-15 00:00:00

  • Targeting the Zinc Transporter ZIP7 in the Treatment of Insulin Resistance and Type 2 Diabetes.

    abstract：:Type 2 diabetes mellitus (T2DM) is a disease associated with dysfunctional metabolic processes that lead to abnormally high levels of blood glucose. Preceding the development of T2DM is insulin resistance (IR), a disorder associated with suppressed or delayed responses to insulin. The effects of this response are pred...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu11020408

    authors： Adulcikas J,Sonda S,Norouzi S,Sohal SS,Myers S

    更新日期：2019-02-15 00:00:00

  • Vitamin D-Binding Protein in Pregnancy and Reproductive Health.

    abstract：:Vitamin D-binding protein (VDBP), the main carrier of vitamin D, has recently been implicated in reproductive health and pregnancy outcomes including endometriosis, polycystic ovary syndrome (PCOS), pre-eclampsia, and gestational diabetes mellitus (GDM). Improved methods for measuring VDBP and an increased understandi...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu12051489

    authors： Fernando M,Ellery SJ,Marquina C,Lim S,Naderpoor N,Mousa A

    更新日期：2020-05-20 00:00:00

  • Undernutrition in patients with COPD and its treatment.

    abstract：:Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disorder of the lung and whole body caused mainly by tobacco smoking. Patients with advanced COPD are in a state of undernutrition, referred to as pulmonary cachexia; the exercise performance and quality of life (QOL) of these patients are deterior...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu5041316

    authors： Itoh M,Tsuji T,Nemoto K,Nakamura H,Aoshiba K

    更新日期：2013-04-18 00:00:00

  • Nutritional Interventions in the Management of Fibromyalgia Syndrome.

    abstract：:Fibromyalgia (FM) is a multifactorial syndrome of unknown etiology, characterized by widespread chronic pain and various somatic and psychological manifestations. The management of FM requires a multidisciplinary approach combining both pharmacological and nonpharmacological strategies. Among nonpharmacological strate...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu12092525

    authors： Pagliai G,Giangrandi I,Dinu M,Sofi F,Colombini B

    更新日期：2020-08-20 00:00:00

  • Effects of Exogenous Dietary Advanced Glycation End Products on the Cross-Talk Mechanisms Linking Microbiota to Metabolic Inflammation.

    abstract：:Heat-processed diets contain high amounts of advanced glycation end products (AGEs). Here we explore the impact of an AGE-enriched diet on markers of metabolic and inflammatory disorders as well as on gut microbiota composition and plasma proteins glycosylation pattern. C57BL/6 mice were allocated into control diet (C...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu12092497

    authors： Mastrocola R,Collotta D,Gaudioso G,Le Berre M,Cento AS,Ferreira Alves G,Chiazza F,Verta R,Bertocchi I,Manig F,Hellwig M,Fava F,Cifani C,Aragno M,Henle T,Joshi L,Tuohy K,Collino M

    更新日期：2020-08-19 00:00:00

  • EEN Yesterday and Today … CDED Today and Tomorrow.

    abstract：:The treatment of Pediatric Crohn's Disease (CD) requires attention both to achieve mucosal healing and to optimize growth, while also maintaining proper bone health. Exclusive Enteral Nutrition (EEN) is recommended as first-line treatment in luminal CD. The therapeutic mechanisms of EEN are being discovered by advance...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu12123793

    authors： Herrador-López M,Martín-Masot R,Navas-López VM

    更新日期：2020-12-10 00:00:00

  • A High Protein Calorie Restriction Diet Alters the Gut Microbiome in Obesity.

    abstract：BACKGROUND:High protein calorie restriction diets have shown clinical efficacy for obesity, but the mechanisms are not fully known. The intestinal microbiome is a mediator of obesity and preclinical data support an effect of high protein diet (HPD) on the gut microbiome of obesity, but there are few studies in humans. ...

    journal_title：Nutrients

    pub_type： 杂志文章

    doi：10.3390/nu12103221

    authors： Dong TS,Luu K,Lagishetty V,Sedighian F,Woo SL,Dreskin BW,Katzka W,Chang C,Zhou Y,Arias-Jayo N,Yang J,Ahdoot A,Li Z,Pisegna JR,Jacobs JP

    更新日期：2020-10-21 00:00:00

  • Up in the Air: Evidence of Dehydration Risk and Long-Haul Flight on Athletic Performance.

    abstract：:The microclimate of an airline cabin consists of dry, recirculated, and cool air, which is maintained at lower pressure than that found at sea level. Being exposed to this distinctive, encapsulated environment for prolonged durations, together with the short-term chair-rest immobilization that occurs during long-haul ...

    journal_title：Nutrients

    pub_type： 杂志文章,评审

    doi：10.3390/nu12092574

    authors： Zubac D,Buoite Stella A,Morrison SA

    更新日期：2020-08-25 00:00:00