Abstract：
INTRODUCTION:Patients with localised and locally advanced renal cancer experience about 20% recurrence during a five-year follow-up period. The aim of the present study was to report recurrence rates and survival in a Danish population with renal cancer. METHODS:Data on patients diagnosed with renal cell carcinoma (RCC) at our institute from January 2005 to December 2013 were collected retrospectively. RESULTS:Overall, 367 patients were diagnosed with RCC during the period, and 78 patients (21%) presented with metastasis. The mean follow-up period for all patients was 41 months (standard deviation = 29, 95% confidence interval: 38-44). The total recurrence rates (RRs) at one, three and five years were 4.5%, 13.5% and 22.3%, respectively. Overall survival rates in the patients who underwent surgery with localised and locally advanced disease were 96.1%, 88.2% and 78.3% for one, three and five years, respectively. The mean time to first recurrence was 26.6 months. The one-year RR was 1.2%, 5.5% and 13.8% for low, intermediate and high-risk Leibovich scores, respectively. The three-year RR was 8.3%, 14.1% and 29.6% for low, intermediate and high-risk Leibovich scores, respectively; and the five-year RR was 12.0%, 26.6% and 52.9% for low, intermediate and high-risk Leibovich scores, respectively. CONCLUSIONS:RRs after localised and locally advanced RCC was 22%. According to the risk of recurrence, we recommend a follow-up programme after nephrectomy with computed tomography every second year for low-risk patients, annually for intermediate-risk patients and every six months for high-risk patients. FUNDING:none. TRIAL REGISTRATION:none.
journal_name
Dan Med Jjournal_title
Danish medical journalauthors
Azawi NH,Tesfalem H,Mosholt KS,Høyerup P,Jensen ES,Malchau E,Fode Msubject
Has Abstractpub_date
2016-04-01 00:00:00issue
4issn
2245-1919pii
A5208journal_volume
63pub_type
杂志文章abstract：INTRODUCTION:Infants with bronchopulmonary dysplasia (BPD) are at high risk of developing cardiovascular sequelae in the form of pulmonary hypertension (PH) which significantly increases morbidity and mortality. The aim of this study was to evaluate the incidence of BPD, to identify characteristics associated with BPD ...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2013-08-01 00:00:00
abstract：:The epidemiology and prognosis of ''fainting'' or syncope has puzzled physicians over the years. Is fainting dangerous? This is a question often asked by the patient--and the answer is ''it depends on a lot of things''. The diverse pathophysiology of syncope and the underlying comorbidites of the patients play an esse...
journal_title：Danish medical journal
pub_type： 杂志文章,评审
doi：
更新日期：2013-09-01 00:00:00
abstract：INTRODUCTION:Marfan syndrome is an autosomal, dominantly inherited disorder of the connective tissue. We report the clinical data and results of a genetic analysis of a large Danish Marfan family. METHODS:Sanger sequencing of FBN1 was initially performed on genomic DNA from the index patient. Subsequently, four affect...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2014-11-01 00:00:00
abstract：:The overall aim of this thesis was to validate the new concept of the Fertility Assessment and Counselling (FAC) Clinic at Rigshospitalet. The intention was to: explore the prognostic value of fertility risk factors by a risk score and provide an estimate of female fecundity, to quantify the impact of oral contracepti...
journal_title：Danish medical journal
pub_type： 杂志文章,评审
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更新日期：2016-10-01 00:00:00
abstract：INTRODUCTION:Treatment of infections in neonates with gentamicin is a balance between optimising bactericidal effect and minimising adverse effects. Previously, at the Neonatal Intensive Care Unit (NICU) at Kolding Hospital, Denmark, neonates suspected of having infections were treated daily with gentamicin 5 mg/kg for...
journal_title：Danish medical journal
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更新日期：2017-06-01 00:00:00
abstract：INTRODUCTION:An indication of the adequacy of the intra-vascular volume is of importance in critically ill patients. The status of the intravascular volume can be determined from a fluid challenge test. Most tests involve invasive monitoring. An exception is the capnographic measurement of changes in end-tidal (ET) CO2...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2019-09-01 00:00:00
abstract：INTRODUCTION:Patients living alone or having a low socioeconomic status are likely to quit cardiac rehabilitation. We aimed to compare patients being offered extended rehabilitation (ERP) with those being offered standard rehabilitation (SRP) as concerns 1) attendance rates and 2) achievement of treatment goals at 12 m...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2013-03-01 00:00:00
abstract：:Difficulties with airway management in relation to general anaesthesia have been a challenge for the anaesthesiologist since the birth of anaesthesia. Massive landmark improvements have been made and general anaesthesia is now regarded as a safe procedure. However, rare, difficult airway management still occurs and it...
journal_title：Danish medical journal
pub_type： 杂志文章,评审
doi：
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:Active surveillance - an initial observational strategy - offers a tailored management of patients with localised prostate cancer. The aim of the strategy is to appoint patients with potentially lethal prostate cancer to curatively intended treatment, while patients with slowly evolving tumours are spared fr...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2015-02-01 00:00:00
abstract：INTRODUCTION:Spontaneous reporting of adverse drug reactions (ADRs) is used for continuous risk-benefit evaluation of marketed pharmaceutical products and for signal detection. The Adverse Drug Event Manager (ADEM) is a service offered to clinicians employed at hospitals in the Capital Region of Denmark. The ADEM assis...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2017-01-01 00:00:00
abstract：INTRODUCTION:Pain and distress during minor hospital-related procedures is a familiar problem in many children. Inadequate relief of children's procedural pain and distress not only affects the experience of the children and their parents, but also adversely impacts procedural success. We aimed to review the safety and...
journal_title：Danish medical journal
pub_type： 杂志文章,评审
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更新日期：2013-06-01 00:00:00
abstract：:Surgeons are increasingly using ultrasonography (US) in their clinical management of patients. However, US is a very user-dependent imaging modality and proper skills of the US operator are needed to ensure quality in patient care. This thesis explores the validity evidence for assessment of competence in abdominal an...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2017-11-01 00:00:00
abstract：INTRODUCTION:Reliable dietary information is crucial for measuring the habitual diet of healthy participants and patients with dyslipidaemia and/or coronary heart disease (CHD). Even so, methods are often complicated and time-consuming for everyone involved. We aimed to validate the new food frequency questionnaire (FF...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2018-11-01 00:00:00
abstract：INTRODUCTION:This is a systematic review of existing literature on the diagnostic modalities and treatment of traumatic abdominal wall hernia caused by bicycle handlebar injury in children. METHODS: A systematic literature search was conducted covering incidents involving children below 17 years of age. Data were extr...
journal_title：Danish medical journal
pub_type： 杂志文章,评审
doi：
更新日期：2018-01-01 00:00:00
abstract：INTRODUCTION:Brachial plexus injuries are usually a result of road traffic accidents and a cause of severe disability that typically affects young adult males. In 2010, a national centre was established for referral of these cases from Danish trauma centres. In this paper, we report on our surgical activity and reflect...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
abstract：INTRODUCTION:There is no consensus among hip surgeons in Denmark on how to follow up patients after total hip arthroplasty (THA). Agreement on the need for radiographic examinations is also lacking. The purpose of this study was to evaluate if routine outpatient post-operative radiographs, obtained three and 12 months ...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2013-04-01 00:00:00
abstract：INTRODUCTION:The use of positron emission tomography with 2-deoxy-2-18F-fluoro-D-glucose integrated with CT (18F-FDG-PET/CT) in oncology is common. Unexpected incidental findings are occasionally recognised and can represent clinically relevant lesions or conditions. This study aims to assess the occurrence, clinical s...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2020-09-07 00:00:00
abstract：INTRODUCTION:Despite rehabilitation programmes offered to all patients with newly diagnosed type 2 diabetes in Denmark, a number of patients either never accomplish good diabetes regulation or the regulation deteriorates with time. Therefore, new approaches are needed. The aim of the present study is to examine whether...
journal_title：Danish medical journal
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2013-12-01 00:00:00
abstract：:Biological rhythms are essential for the regulation of many life processes. Disturbances of the circadian rhythm are known to affect human health, performance and well-being and the negative consequences are numerous and widespread. Cognitive dysfunction, fatigue, pain, sleep disturbances and mood disorders, such as a...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2014-09-01 00:00:00
abstract：INTRODUCTION:Establishment of sufficient muscle relaxation is essential in laparoscopic surgery. During laparoscopy, surgeons can experience abdominal contractions in their patients. Deep neuromuscular block (NMB) has the potential to prevent such episodes. In this study, we explored if deep NMB reduces the incidence o...
journal_title：Danish medical journal
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2017-05-01 00:00:00
abstract：INTRODUCTION:Difficult airway management is associated with an increased risk of morbidity and mortality. Several preoperative risk factors associated with airway management difficulties have been proposed; however, no clear guideline for airway assessments exists. We therefore hypothesised that Danish airway assessmen...
journal_title：Danish medical journal
pub_type： 杂志文章,多中心研究
doi：
更新日期：2016-10-01 00:00:00
abstract：INTRODUCTION:Patients' non-attendance is a significant problem in modern healthcare. Non-attendance delays treatment, reduces efficiency and increases healthcare costs. For several years, the introduction of financial incentives such as a non-attendance fee has been discussed in Denmark. Set in the context of a tax-fin...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2016-07-01 00:00:00
abstract：:Today, sentinel lymph node dissection (SLND) has replaced axillary lymph node dissection (ALND) as standard procedure for staging of the axilla in the treatment of breast cancer. SLND can accurately stage the axilla by removing on average only two lymph nodes. Only in case of metastatic spread to sentinel nodes an ALN...
journal_title：Danish medical journal
pub_type： 杂志文章,评审
doi：
更新日期：2012-07-01 00:00:00
abstract：INTRODUCTION:Cell-free DNA testing (cfDNA testing) in maternal plasma has recently been implemented in Danish healthcare. Prior to that we wanted to evaluate the preferences among pregnant women, partners and health professionals regarding cfDNA testing compared with invasive prenatal diagnostics. METHODS:Responders w...
journal_title：Danish medical journal
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doi：
更新日期：2018-05-01 00:00:00
abstract：:Hip dysplasia and hip joint deformities in general are recognized as possible precursors of osteoarthritic development. Early and correct identification of hip dysplasia is important in order to offer timely joint preserving treatment. In the contemporary literature, several controversies exist, and some of these were...
journal_title：Danish medical journal
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doi：
更新日期：2012-06-01 00:00:00
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journal_title：Danish medical journal
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doi：
更新日期：2015-01-01 00:00:00
abstract：INTRODUCTION:In order to optimise the selection process for admission to specialist training in family medicine, we developed a new design for structured applications and selection interviews. The design contains semi-structured interviews, which combine individualised elements from the applications with standardised b...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2013-09-01 00:00:00
abstract：:Kidney cancer (Renal Cell Carcinoma (RCC)) is one of the most deadly malignancies due to frequent late diagnosis and poor treatment options. Histologically, RCC embraces a wide variety of different subtypes with the clear cell variant (ccRCC) being the most common, accounting for 75-90% of all RCCs. At present, the su...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2017-10-01 00:00:00
abstract：INTRODUCTION:Patients with bronchiectasis suffer from breathlessness, cough and sputum production, which impairs quality of life. The Bronchiectasis Health Questionnaire (BHQ), a short and disease-specific questionnaire, has previously been developed and validated in English. The aim of this study was to translate and ...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2020-03-01 00:00:00
abstract：INTRODUCTION:The Danish Adult Diabetes Database (DADD) annually reports a quality indicator for lipid-lowering treatment of type 2 diabetes mellitus (T2DM) patients. This retrospective cohort study aims to A) investigate the reasons for inadequate or lacking lipid-lowering treatment and to B) assess the validity of the...
journal_title：Danish medical journal
pub_type： 杂志文章
doi：
更新日期：2018-09-01 00:00:00
