Development of a multivariable model to predict vulnerability in older American patients hospitalised with cardiovascular disease.

abstract：OBJECTIVES:Low-dose methoxyflurane is a non-opioid, inhaled analgesic administered via the Penthrox inhaler and was recently licensed in Europe for emergency relief of moderate-to-severe trauma-associated pain in conscious adults. This non-interventional study investigated occupational exposure to methoxyflurane in the...

journal_title：BMJ open

authors： Frangos J,Belbachir A,Dautheville S,Jung C,Herklotz K,Amon F,Dickerson S,Chomier B

更新日期：2020-02-10 00:00:00

abstract：INTRODUCTION:Orthotopic liver transplantation (OLT) has emerged as the mainstay of treatment for end-stage liver disease. In an attempt to improve the availability of donor allografts and reduce waiting list mortality, graft acceptance criteria were extended increasingly over the decades. The use of extended criteria d...

journal_title：BMJ open

authors： Czigany Z,Schöning W,Ulmer TF,Bednarsch J,Amygdalos I,Cramer T,Rogiers X,Popescu I,Botea F,Froněk J,Kroy D,Koch A,Tacke F,Trautwein C,Tolba RH,Hein M,Koek GH,Dejong CHC,Neumann UP,Lurje G

更新日期：2017-10-10 00:00:00

abstract：OBJECTIVES:To investigate the relationship between low-density lipoprotein cholesterol (LDL-C) and all-cause mortality among middle-aged and elderly Chinese population. DESIGN:Prospective cohort study. SETTING:This study used data from the China Health and Retirement Longitudinal Study. PARTICIPANTS:Middle-aged and ...

journal_title：BMJ open

authors： Zhou L,Wu Y,Yu S,Shen Y,Ke C

更新日期：2020-08-16 00:00:00

abstract：INTRODUCTION:Many types of audits are commonly used in hospital care to promote quality improvements. However, the evidence on the effectiveness of audits is mixed. The objectives of this proposed realist review are (1) to understand how and why audits might, or might not, work in terms of delivering the intended outco...

journal_title：BMJ open

authors： Hut-Mossel L,Welker G,Ahaus K,Gans R

更新日期：2017-06-14 00:00:00

abstract：INTRODUCTION:Obese patients with type 2 diabetes undergoing bariatric surgery experience significant and lasting weight loss and improved glycaemic control. However, bariatric surgical procedures such as Roux-en-Y gastric bypass are irreversible and associated with considerable short-term and long-term risks. The EndoB...

journal_title：BMJ open

authors： Rohde U,Hedbäck N,Gluud LL,Vilsbøll T,Knop FK

更新日期：2013-09-13 00:00:00

abstract：INTRODUCTION:Obesity is significant risk factor for venous thromboembolism (VTE); however, the related mechanisms remain unclear. Previous studies have suggested that this might be related to physical factors including anthropometric measures. We intend to conduct a systematic review and meta-analysis of prospective st...

journal_title：BMJ open

authors： Kaze AD,Bigna JJ,Nansseu JR,Noubiap JJ

更新日期：2018-03-31 00:00:00

abstract：INTRODUCTION:Treatment fidelity is an important and often neglected component of complex behaviour change research. It is central to understanding treatment effects, especially for evaluations conducted outside of highly controlled research settings. Ensuring that promising interventions can be delivered adequately (ie...

journal_title：BMJ open

authors： Beck AK,Forbes E,Baker AL,Britton B,Oldmeadow C,Carter G

更新日期：2019-07-30 00:00:00

abstract：OBJECTIVE:To assess the 24-month cost-effectiveness of total knee replacement (TKR) plus non-surgical treatment compared with non-surgical treatment with the option of later TKR if needed. METHODS:100 adults with moderate-to-severe knee osteoarthritis found eligible for TKR by an orthopaedic surgeon in secondary care ...

journal_title：BMJ open

authors： Skou ST,Roos E,Laursen M,Arendt-Nielsen L,Rasmussen S,Simonsen O,Ibsen R,Larsen AT,Kjellberg J

更新日期：2020-01-15 00:00:00

abstract：PURPOSE:The Buffalo Osteoporosis and Periodontal Disease (OsteoPerio) study is a prospective cohort study focused on the relationship between the microbiome and oral and systemic health outcomes in postmenopausal women. The cohort was established to examine how the oral microbiome is affected by (and how it affects) pe...

journal_title：BMJ open

authors： Banack HR,Genco RJ,LaMonte MJ,Millen AE,Buck MJ,Sun Y,Andrews CA,Hovey KM,Tsompana M,McSkimming DI,Zhao J,Wactawski-Wende J,OsteoPerio Study Group.

更新日期：2018-12-04 00:00:00

abstract：PURPOSE:Occupational and environmental exposures remain important modifiable risk factors of public health. Existing cohort studies are often limited by the level of detail of data collected on these factors and health. It is also often assumed that the more healthy group is over-represented in cohort studies, which is...

journal_title：BMJ open

authors： Slottje P,Yzermans CJ,Korevaar JC,Hooiveld M,Vermeulen RC

更新日期：2014-11-26 00:00:00

abstract：OBJECTIVES:Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) emergence is a major public health concern. This study was aimed at assessing risk factors for persistently carrying MRSA in veal calf farmers and their family members. We also evaluate the dynamics of MRSA environmental load during t...

journal_title：BMJ open

authors： Dorado-García A,Bos ME,Graveland H,Van Cleef BA,Verstappen KM,Kluytmans JA,Wagenaar JA,Heederik DJ

更新日期：2013-09-19 00:00:00

abstract：BACKGROUND:Delirium is common among seniors discharged from the emergency department (ED) and associated with increased risk of mortality. Prior research has addressed mortality associated with seniors discharged from the ED with delirium, however has generally relied on data from one or a small number of institutions ...

journal_title：BMJ open

authors： Israni J,Lesser A,Kent T,Ko K

更新日期：2018-05-05 00:00:00

abstract：OBJECTIVES:To assess the costs of hospital accreditation in Australia. DESIGN:Mixed methods design incorporating: stakeholder analysis; survey design and implementation; activity-based costs analysis; and expert panel review. SETTING:Acute care hospitals accredited by the Australian Council for Health Care Standards....

journal_title：BMJ open

authors： Mumford V,Greenfield D,Hogden A,Forde K,Westbrook J,Braithwaite J

更新日期：2015-09-08 00:00:00

abstract：INTRODUCTION:Rapid, robust and continually updated evidence synthesis is required to inform management of COVID-19 in pregnant and postpartum women and to keep pace with the emerging evidence during the pandemic. METHODS AND ANALYSIS:We plan to undertake a living systematic review to assess the prevalence, clinical ma...

journal_title：BMJ open

authors： Yap M,Debenham L,Kew T,Chatterjee SR,Allotey J,Stallings E,Coomar D,Lee SI,Qiu X,Yuan M,Clavé Llavall A,Dixit A,Zhou D,Balaji R,van Wely M,Kostova E,van Leeuwen E,Mofenson L,Kunst H,Khalil A,Tiberi S,Thomas J,

更新日期：2020-12-02 00:00:00

abstract：OBJECTIVES:To complete a 30-year interrupted time-series analysis of the impact of austerity-related and prosperity-related events on the occurrence of suicide across Greece. SETTING:Greece from 1 January 1983 to 31 December 2012. PARTICIPANTS:A total of 11 505 suicides, 9079 by men and 2426 by women, occurring in Gr...

journal_title：BMJ open

authors： Branas CC,Kastanaki AE,Michalodimitrakis M,Tzougas J,Kranioti EF,Theodorakis PN,Carr BG,Wiebe DJ

更新日期：2015-02-02 00:00:00

abstract：OBJECTIVES:Child dental caries is a global public health challenge with high prevalence and wide inequalities. A complex public health programme (Childsmile) was established. We aimed to evaluate the reach of the programme and its impact on child oral health. SETTING:Education, health and community settings, Scotland-...

journal_title：BMJ open

authors： Kidd JB,McMahon AD,Sherriff A,Gnich W,Mahmoud A,Macpherson LM,Conway DI

更新日期：2020-11-24 00:00:00

abstract：INTRODUCTION:Though the importance of knowledge mobilisation has been established globally in health and wellness research, a certain degree of ambiguity remains regarding the meaning and extent of knowledge mobilisation activities and how they have been implemented. In this study, we aim to explore the different descr...

journal_title：BMJ open

authors： Turin TC,Chowdhury N,Vaska M,Rumana N,Lasker MAA,Chowdhury MZI

更新日期：2020-04-08 00:00:00

abstract：OBJECTIVES:To examine the effect on estimated levels of health conditions produced from large-scale surveys, when either list-wise respondent deletion or standard demographic item-level imputation is employed. To assess the degree to which further bias reduction results from the inclusion of correlated ancillary variab...

journal_title：BMJ open

authors： Frankel MR,Battaglia MP,Balluz L,Strine T

更新日期：2012-07-12 00:00:00

abstract：OBJECTIVES:There is a controversy about the impact of economic crisis on suicide rates in Greece. We analysed recent suicide data to identify who has been most affected and the relationships to economic and labour market indicators. SETTING:Greece. PRIMARY AND SECONDARY OUTCOME MEASURES:Age-specific and sex-specific ...

journal_title：BMJ open

authors： Rachiotis G,Stuckler D,McKee M,Hadjichristodoulou C

更新日期：2015-03-25 00:00:00

abstract：INTRODUCTION:Clinical depression is a substantial problem among adolescents, increasing significantly at about age 15 years. It causes impairment in social, academic and familial relationships, as well as ongoing cognitive and emotional difficulties for the individual. A study in Iceland demonstrated that a cognitive-b...

journal_title：BMJ open

authors： Wikberg C,Augustsson P,Sveinsdottir G,Craighead WE,Arnarson EÖ,Marteinsdottir I,Lilja JL

更新日期：2021-01-22 00:00:00

abstract：OBJECTIVE:This study aimed to characterise rheumatic manifestations and autoantibodies in 432 patients diagnosed with infective endocarditis (IE) in Shanghai. DESIGN, SETTING AND PARTICIPANTS:A retrospective study was conducted in Ruijin Hospital from 1997 to 2017. The clinical and laboratory characteristics of a tota...

journal_title：BMJ open

authors： Zhou Z,Ye J,Teng J,Liu H,Cheng X,Sun Y,Su Y,Chi H,Wang F,Yang C,Jin W

更新日期：2020-02-12 00:00:00

abstract：OBJECTIVE:The association between obesity and disability may differ between high-income and low-income/middle-income countries but there are no studies comparing this association between these settings. The aim of the study was to assess this association in nine countries using nationally-representative data from the C...

journal_title：BMJ open

authors： Koyanagi A,Moneta MV,Garin N,Olaya B,Ayuso-Mateos JL,Chatterji S,Leonardi M,Sainio P,Galas A,Haro JM

更新日期：2015-04-02 00:00:00

abstract：OBJECTIVE:We report on: (1) the proportion of patients with known atrial fibrillation (AF); and (2) demographic, clinical or radiological differences between patients with known AF (and not treated) and patients with newly diagnosed AF, in a cohort of patients who presented with ischaemic stroke or transient ischaemic ...

journal_title：BMJ open

authors： Wilson D,Ambler G,Shakeshaft C,Banerjee G,Charidimou A,Seiffge D,White M,Cohen H,Yousry T,Salman R,Lip GYH,Muir K,Brown MM,Jäger HR,Werring DJ,CROMIS-2 collaborators.

更新日期：2019-07-24 00:00:00

abstract：BACKGROUND:X linked intellectual disability (XLID) syndromes account for a substantial number of males with ID. Much progress has been made in identifying the genetic cause in many of the syndromes described 20-40 years ago. Next generation sequencing (NGS) has contributed to the rapid discovery of XLID genes and ident...

journal_title：BMJ open

authors： Friez MJ,Brooks SS,Stevenson RE,Field M,Basehore MJ,Adès LC,Sebold C,McGee S,Saxon S,Skinner C,Craig ME,Murray L,Simensen RJ,Yap YY,Shaw MA,Gardner A,Corbett M,Kumar R,Bosshard M,van Loon B,Tarpey PS,Abidi F,G

更新日期：2016-04-29 00:00:00

abstract：INTRODUCTION:The proportion of elderly people is steadily rising worldwide, especially in low-income and middle-income countries, including China. Chronic kidney disease (CKD) is a common disorder in older people. However, little is known about the epidemiology of CKD and its consequences among the elderly. Improvement...

journal_title：BMJ open

authors： Liang S,Wang WL,Zhu FL,Duan SW,Sun XF,Chen XM,Cai GY,Chinese observational prospective study of ageing population with chronic kidney disease (C-OPTION).

更新日期：2018-02-24 00:00:00

abstract：OBJECTIVE:To evaluate sex-specific and age-specific associations of active living environments (ALEs) with premature cardiometabolic mortality. DESIGN:Population-based retrospective cohort study. SETTING:Residential neighbourhoods (1000-metre circular buffers from the centroids of dissemination areas) across Canada f...

journal_title：BMJ open

authors： Mah SM,Sanmartin C,Riva M,Dasgupta K,Ross NA

更新日期：2020-11-20 00:00:00

abstract：OBJECTIVES:Develop predictive models for a paediatric population that provide information for paediatricians and health authorities to identify children at risk of hospitalisation for conditions that may be impacted through improved patient care. DESIGN:Retrospective healthcare utilisation analysis with multivariable ...

journal_title：BMJ open

authors： Louis DZ,Callahan CA,Robeson M,Liu M,McRae J,Gonnella JS,Lombardi M,Maio V

更新日期：2018-05-05 00:00:00

abstract：OBJECTIVES:There is an emergent body of evidence supporting exercise therapy and physical activity in the management of musculoskeletal pain. The purpose of this study was to explore potential barriers and facilitators with patients and physiotherapists with patellofemoral pain involved in a feasibility randomised cont...

journal_title：BMJ open

authors： Smith BE,Moffatt F,Hendrick P,Bateman M,Selfe J,Rathleff MS,Smith TO,Logan P

更新日期：2019-06-03 00:00:00

abstract：INTRODUCTION:Governments in different countries have committed to better use of evidence from research in policy. Although many programmes are directed at assisting agencies to better use research, there have been few tests of the effectiveness of such programmes. This paper describes the protocol for SPIRIT (Supportin...

journal_title：BMJ open

authors： CIPHER Investigators.

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVES:Injury is an important issue in public health. Spinal curvature disorders are deformities characterised by excessive curves of the spine. The prevalence of spinal curvature disorders is not low, but its relationship with injury has not been studied. The aim of this study is to investigate whether spinal curv...

journal_title：BMJ open

authors： Kuo YL,Chung CH,Huang TW,Tsao CH,Chang SY,Peng CK,Cheng WE,Chien WC,Shen CH

更新日期：2019-01-17 00:00:00