Abstract:
INTRODUCTION:Obesity is significant risk factor for venous thromboembolism (VTE); however, the related mechanisms remain unclear. Previous studies have suggested that this might be related to physical factors including anthropometric measures. We intend to conduct a systematic review and meta-analysis of prospective studies to summarise the extant literature on the associations between a set of seven measures of body size and the risk of VTE. METHODS AND ANALYSIS:The current systematic review will include prospective cohort studies assessing the association between seven measures of body size (height, weight, body mass index, waist and hip circumferences, waist-to-hip ratio, waist-to-height ratio) and the risk of VTE. We will conduct comprehensive searches of MEDLINE and Excerpta Medica Database (EMBASE) for articles published from inception through 31 August 2017, without any language restriction. Two investigators will independently screen, select studies and perform data extraction and risk of bias assessment, with discrepancies resolved by a third investigator. For each body size measure, study-specific relative risks will be pooled using random effects meta-analysis models. Statistical heterogeneity will be assessed using Cochran's Q statistic, H and the I2 statistics. Sources of heterogeneity will be investigated using subgroup and meta-regression analyses as deemed appropriate. Publication bias will be assessed with funnel plots supplemented by Egger's test. ETHICS AND DISSEMINATION:This systematic review will use data from published literature; therefore, ethical approval is not required. We expect our findings to supplement previous epidemiological studies by providing an updated and comprehensive synthesis of the available evidence on the association between body size measures and risk of VTE in the general population. Findings will be published in peer-reviewed journal and presented at scientific meetings. PROSPERO REGISTRATION NUMBER:CD CRD42017071996.
journal_name
BMJ Openjournal_title
BMJ openauthors
Kaze AD,Bigna JJ,Nansseu JR,Noubiap JJdoi
10.1136/bmjopen-2017-018958subject
Has Abstractpub_date
2018-03-31 00:00:00pages
e018958issue
3issn
2044-6055pii
bmjopen-2017-018958journal_volume
8pub_type
杂志文章相关文献
BMJ Open文献大全abstract:OBJECTIVES:To establish the rates of publication and reporting of results for interventional clinical trials across Polish academic medical centres (AMCs) completed between 2009 and 2013. We aim also to compare the publication and reporting success between adult and paediatric trials. DESIGN:Cross-sectional study. SE...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034666
更新日期:2020-01-22 00:00:00
abstract:OBJECTIVES:The study aimed to understand through qualitative research what patients considered material in their decision to consent to an acute surgical intervention. PARTICIPANTS, SETTING AND INTERVENTION:The patients selected aged between 18 and 90, having been admitted to a major trauma centre to undergo an acute ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-037657
更新日期:2020-10-08 00:00:00
abstract:OBJECTIVE:Treatment gradients by socioeconomic status have been observed within cancer care in several countries. The objective of this study was to explore whether patients' educational level and social network influence oncologists' clinical decision-making. DESIGN:Semi-structured interviews on factors considered wh...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2012-001248
更新日期:2012-08-24 00:00:00
abstract:INTRODUCTION:Parkinson's disease is the second most common chronic neurodegenerative condition with bladder dysfunction affecting up to 71%. Symptoms affect quality of life and include urgency, frequency, hesitancy, nocturia and incontinence. Addressing urinary dysfunction is one of the top 10 priority research areas i...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034887
更新日期:2020-02-17 00:00:00
abstract:INTRODUCTION:Atrial fibrillation (AF) affects 10% of patients undergoing cardiac surgery and is an independent risk factor for all-cause mortality, ischaemic stroke and heart failure. Surgical AF ablation has been shown to significantly improve maintenance of sinus rhythm, however, small to medium size trials conducted...
journal_title:BMJ open
pub_type: 杂志文章,meta分析
doi:10.1136/bmjopen-2016-013273
更新日期:2016-11-02 00:00:00
abstract:BACKGROUND:Dual antiplatelet therapy (DAPT) is frequently discontinued after drug-eluting stent (DES) implantation, which could increase the risk of major adverse cardiovascular events (MACEs). Few studies have attempted to improve DAPT adherence through web-based social media. OBJECTIVE:To explore the effect of socia...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033017
更新日期:2020-01-07 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess the knowledge and practice of health workers about multidrug-resistant tuberculosis (MDR-TB) prevention and control. STUDY DESIGN AND SETTINGS:A cross-sectional study was conducted at Gondar University Referral Hospital and Felege Hiwot Referral Hospital. PARTICIPANTS:Ran...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究
doi:10.1136/bmjopen-2018-022948
更新日期:2019-02-19 00:00:00
abstract:OBJECTIVES:The establishment of the Family Physician (FP) programme in the rural areas of Iran in 2005 has made health services accessible and affordable. This paper aims to assess the overall trends of maternal and child health (MCH) indicators in a 20-year period and possible effects of the FP programme (intervention...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-021761
更新日期:2019-01-15 00:00:00
abstract:INTRODUCTION:Severe and persistent mental illness (SPMI) can significantly impact a person's social, personal and professional life. Previous studies have demonstrated pharmacists' roles in mental healthcare; however, limited studies to date have focused on pharmacists' roles in providing healthcare services, specifica...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-038270
更新日期:2020-07-13 00:00:00
abstract:OBJECTIVES:We aimed to provide previously unestablished information on population-based differences in cause-specific sickness absence trends between occupational classes and further between four large industrial sectors within the different occupational classes while controlling for other socioeconomic factors and emp...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-019822
更新日期:2018-04-07 00:00:00
abstract:INTRODUCTION:Patients presenting with acute intracerebral haemorrhage are at a high risk of exhibiting haematoma expansion, a phenomenon that can significantly worsen long-term functioning. Numerous clinical and radiological factors are associated with expansion. In a bid to better select patients at increased risk of ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-024744
更新日期:2019-01-21 00:00:00
abstract:INTRODUCTION:Current international guidelines recommend non-vitamin K oral anticoagulants (NOACs) for stroke prevention among patients with non-valvular atrial fibrillation (AF) at significant ischaemic stroke risk given the superior safety and comparable efficacy of NOACs over warfarin. Nonetheless, the safety and eff...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-038194
更新日期:2020-09-25 00:00:00
abstract:OBJECTIVES:To analyse free-text responses from the first Scottish Cancer Patient Experience Survey (SCPES) to understand patients' experiences of care, identify valued aspects and areas for improvement. DESIGN:Inductive thematic analysis of seven free-text comment boxes covering all stages of the cancer experience, fr...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-015726
更新日期:2017-06-15 00:00:00
abstract:OBJECTIVES:This study aimed to determine the seroprevalence of Toxoplasma gondii (T. gondii) infection in pregnant women in Matehuala City, Mexico; and the associated risk factors. DESIGN:A cross-sectional study. SETTING:Matehuala City, Mexico. PARTICIPANTS:311 pregnant women. PRIMARY AND SECONDARY OUTCOME MEASURES...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-033995
更新日期:2020-08-06 00:00:00
abstract:OBJECTIVE:Exposure to electric shock has been associated with an increased risk of developing delayed cardiac arrhythmias and cardiac diseases. We examined whether electric shock patients have an increased risk of developing cardiac disease, cardiac arrhythmias or death compared with the general Danish population. DES...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-015967
更新日期:2017-08-28 00:00:00
abstract:OBJECTIVES:To assess which osmolarity equation best predicts directly measured serum/plasma osmolality and whether its use could add value to routine blood test results through screening for dehydration in older people. DESIGN:Diagnostic accuracy study. PARTICIPANTS:Older people (≥65 years) in 5 cohorts: Dietary Stra...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-008846
更新日期:2015-10-21 00:00:00
abstract:OBJECTIVE:There have been calls to remove 'carcinoma' from terminology for in situ cancers such as ductal carcinoma in situ (DCIS), to reduce overdiagnosis and overtreatment. We investigated the effect of describing DCIS as 'abnormal cells' versus 'pre-invasive breast cancer cells' on women's concern and treatment pref...
journal_title:BMJ open
pub_type: 杂志文章,随机对照试验
doi:10.1136/bmjopen-2015-008094
更新日期:2015-11-02 00:00:00
abstract:OBJECTIVES:Sierra Leone has one of the highest maternal mortality ratios in the world. Timely and well-coordinated referrals are necessary to reduce delays in providing adequate care for women with obstetric complications. This study describes factors affecting timely and adequate referral of women with obstetric compl...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-041746
更新日期:2020-12-10 00:00:00
abstract:OBJECTIVES:This study examined National Health Insurance claims data to investigate the epidemiology of shoulder disorders in Korea. Detailed information on medical services and related costs was assessed by major shoulder disorder category. DESIGN AND SETTING:The 2014 National Patient Sample dataset provided by the H...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2017-015848
更新日期:2017-07-12 00:00:00
abstract:TRIAL DESIGN:Cluster randomised controlled trial. OBJECTIVE:To compare current practice for encouraging homeless people to be screened for tuberculosis on a mobile digital X-ray unit in London, UK, with the additional use of volunteer peer educators who have direct experience of tuberculosis, homelessness or both. PA...
journal_title:BMJ open
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/bmjopen-2015-008050
更新日期:2015-09-21 00:00:00
abstract:OBJECTIVE:The COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the clinical course of hospitalised patients, particularly in the USA. We aimed to compare clinical characteristic of patients with COVID-19 who had in-hospital mortality ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-040736
更新日期:2020-11-27 00:00:00
abstract:OBJECTIVE:New electronic devices offer an opportunity within routine primary care settings for improving the detection of atrial fibrillation (AF), which is a common cardiac arrhythmia and a modifiable risk factor for stroke. We aimed to assess the performance of a modified blood pressure (BP) monitor and two single-le...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2013-004565
更新日期:2014-05-02 00:00:00
abstract:OBJECTIVES:To investigate the accuracy, reproducibility and costs of different laboratory assays for the monitoring of unfractionated heparin (UFH) in clinical practice and to study test utilisation in Switzerland. DESIGN:Prospective evaluation study and survey among Swiss hospitals and laboratories. SETTING:Secondar...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-022943
更新日期:2018-06-09 00:00:00
abstract:INTRODUCTION:Ageing-related processes such as cellular senescence are believed to underlie the accumulation of diseases in time, causing (co)morbidity, including cancer, thromboembolism and stroke. Interfering with these processes may delay, stop or reverse morbidity. The aim of this study is to investigate the link be...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2020-039560
更新日期:2020-12-17 00:00:00
abstract:INTRODUCTION:Diabetic macular oedema (DMO) and proliferative diabetic retinopathy (PDR) are the major causes of sight loss in people with diabetes. Due to the increased prevalence of diabetes, the workload related to these complications is increasing making it difficult for Hospital Eye Services (HSE) to meet demands. ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-027795
更新日期:2019-06-28 00:00:00
abstract:OBJECTIVES:The purpose of this study was to determine the frequency of select adverse childhood experiences (ACEs) among a sample of American Indian (AI) adults living with type 2 diabetes (T2D) and the associations between ACEs and self-rated physical and mental health. We also examined associations between sociocultu...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2018-022265
更新日期:2018-09-19 00:00:00
abstract:OBJECTIVE:Recent studies have suggested that stress in a pregnant mother may affect the future health of the unborn child negatively. An excellent proxy for health problems is the use of healthcare resources. Using nationwide data, we examined whether persons born to mothers who lost a close relative during pregnancy h...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2014-005657
更新日期:2015-01-08 00:00:00
abstract:INTRODUCTION:Despite the significant disease burden of bronchiectasis in Korea, no large-scale, representative prospective cohort studies have been conducted to evaluate the clinical characteristics of Korean patients with bronchiectasis, indicating an urgent need for cohort studies on bronchiectasis. METHODS AND ANAL...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2019-034090
更新日期:2020-01-19 00:00:00
abstract:OBJECTIVES:Studies on ethnic disparities in glycaemic control have been contradictory, and compromised by excessively broad categories of ethnicity and inadequate adjustment for socioeconomic differences. We aimed to study the effect of ethnicity on glycaemic control in a large cohort of patients with type 2 diabetes. ...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2015-007599
更新日期:2015-06-05 00:00:00
abstract:OBJECTIVE:Radiation fears following Japan's 2011 Fukushima nuclear disaster affected levels of physical activity in local children. We assessed the postdisaster versus predisaster weight status in school children and evaluated to what extent school restrictions on outdoor activities that were intended to reduce radiati...
journal_title:BMJ open
pub_type: 杂志文章
doi:10.1136/bmjopen-2016-013145
更新日期:2016-09-28 00:00:00