Clinical characteristics of infective endocarditis in patients with antineutrophil cytoplasmic antibody or antiphospholipid antibody: a retrospective study in Shanghai.

abstract：INTRODUCTION:Governments in different countries have committed to better use of evidence from research in policy. Although many programmes are directed at assisting agencies to better use research, there have been few tests of the effectiveness of such programmes. This paper describes the protocol for SPIRIT (Supportin...

journal_title：BMJ open

authors： CIPHER Investigators.

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:Radiation fears following Japan's 2011 Fukushima nuclear disaster affected levels of physical activity in local children. We assessed the postdisaster versus predisaster weight status in school children and evaluated to what extent school restrictions on outdoor activities that were intended to reduce radiati...

journal_title：BMJ open

authors： Nomura S,Blangiardo M,Tsubokura M,Ochi S,Hodgson S

更新日期：2016-09-28 00:00:00

abstract：OBJECTIVES:To evaluate patient experiences of specific aspects of haemodialysis care across several countries. DESIGN:Cross-sectional survey using the Choices for Healthy Outcomes in Caring for End-Stage Renal Disease (CHOICE) questionnaire. SETTING:Haemodialysis clinics within a single provider in Europe and South A...

journal_title：BMJ open

authors： Palmer SC,de Berardis G,Craig JC,Tong A,Tonelli M,Pellegrini F,Ruospo M,Hegbrant J,Wollheim C,Celia E,Gelfman R,Ferrari JN,Törok M,Murgo M,Leal M,Bednarek-Skublewska A,Dulawa J,Strippoli GF

更新日期：2014-05-19 00:00:00

abstract：OBJECTIVES:The local care and treatment of liver disease (LOCATE) intervention embedded specialist liver nurses in general practitioner (GP) practices to improve the identification of progressive liver disease, enabling earlier intervention. This current process evaluation examines GP practice staffs' perceptions of th...

journal_title：BMJ open

authors： Reinson T,Bradbury K,Moore M,Sheron N

更新日期：2019-05-22 00:00:00

abstract：OBJECTIVE:To complete a systematic review of the literature describing associations between all environmental exposures and asthma symptoms and exacerbations in children up to mean age of 9 years. DESIGN:Systematic review. SETTING:Reference lists of identified studies and reviews were searched for all articles publis...

journal_title：BMJ open

authors： Dick S,Doust E,Cowie H,Ayres JG,Turner S

更新日期：2014-02-12 00:00:00

abstract：INTRODUCTION:Surgery is the standard curative treatment for lung cancer but is only possible in patients with local tumour and preserved exercise capacity. Improving fitness before surgery can reduce postoperative complications and mortality. However, preoperative rehabilitation remains difficult to implement for sever...

journal_title：BMJ open

authors： Laurent H,Galvaing G,Thivat E,Coudeyre E,Aubreton S,Richard R,Kwiatkowski F,Costes F,Filaire M

更新日期：2017-11-12 00:00:00

abstract：PURPOSE:Psoriasis is a chronic inflammatory skin disease that frequently debuts in childhood and adolescence. We wished to determine environmental and genetic risk factors for the development of psoriasis in children and adolescents, as well as to investigate debut type, trigger factors, course of disease, nature and i...

journal_title：BMJ open

authors： Blegvad C,Andersen AN,Groot J,Zachariae C,Skov L

更新日期：2019-09-24 00:00:00

abstract：INTRODUCTION:Anticoagulants are arguably the most important drug family of all, based on the frequency and duration of their use, and the clinical importance and frequency of benefits and harms. Several direct acting oral anticoagulants (DOACs) have recently joined warfarin for the treatment of atrial fibrillation, wit...

journal_title：BMJ open

authors： Holbrook A,Dormuth C,Morrow R,Lee A,Troyan S,Li G,Pullenyegum E

更新日期：2016-11-24 00:00:00

abstract：OBJECTIVES:The rate of total knee arthroplasty surgery (TKA) is rising in Australia despite varying impacts of TKA on physical function (PF) in population-based studies. There are potentially modifiable risk factors that could enhance PF after TKA, so we evaluated (1) the levels of PF in persons with TKA and the rest o...

journal_title：BMJ open

authors： Rogers KD,Blyth FM,March LM,Jorm L

更新日期：2013-07-08 00:00:00

abstract：OBJECTIVE:To quantify general practitioners' (GPs) sensitivity to anxiety disorders (ADs) when confronted with the range of symptoms common to children with ADs. Also, to explore GPs' conscious preferences and implicit tendencies for referral of children with ADs to mental healthcare. DESIGN AND SETTING:In a cross-sec...

journal_title：BMJ open

authors： Aydin S,Crone MR,Siebelink BM,Vermeiren RRJM,Numans ME,Westenberg PM

更新日期：2020-04-15 00:00:00

abstract：IMPORTANCE:The Use of a Multidrug Pill In Reducing cardiovascular Events (UMPIRE) trial has shown improved adherence with the use of a polypill strategy when compared with usual medications for cardiovascular disease (CVD) prevention. To advance from efficacy to impact, we need a better understanding of why and how suc...

journal_title：BMJ open

authors： Wood F,Salam A,Singh K,Day S,Jan S,Prabhakaran D,Rodgers A,Patel A,Thom S,Ward H

更新日期：2015-09-30 00:00:00

abstract：OBJECTIVE:The diagnosis of transient ischaemic attack (TIA) based on symptoms and signs can be challenging and would greatly benefit from a rapid serum biomarker of brain ischaemia. We aimed to quantify the added diagnostic value of serum biomarkers in patients suspected of TIA beyond symptoms and signs. METHODS:This ...

journal_title：BMJ open

authors： Dolmans LS,Rutten F,Bartelink MEL,van Dijk EJ,Nederkoorn PJ,Kappelle J,Hoes AW,MIND-TIA study group.

更新日期：2019-10-17 00:00:00

abstract：OBJECTIVES:To compare the efficacy of hypnotherapy versus gabapentin for the treatment of hot flashes in breast cancer survivors, and to evaluate the feasibility of conducting a clinical trial comparing a drug with a complementary or alternative method (CAM). DESIGN:Prospective randomised trial. SETTING:Breast health...

journal_title：BMJ open

authors： Maclaughlan David S,Salzillo S,Bowe P,Scuncio S,Malit B,Raker C,Gass JS,Granai CO,Dizon DS

更新日期：2013-09-10 00:00:00

abstract：OBJECTIVES:Previous qualitative research investigating the experiences of women diagnosed with gestational diabetes (GD) has provided important insights into the development of behaviour change interventions. However, these studies often lack a theoretical underpinning. This study explored the use of the capability, op...

journal_title：BMJ open

authors： Boyd J,McMillan B,Easton K,Delaney B,Mitchell C

更新日期：2020-08-04 00:00:00

abstract：OBJECTIVES:Multimorbidity, defined as the presence of 2 or more chronic medical conditions in an individual, is associated with poorer health outcomes. Several multimorbidity measures exist, and the challenge is to decide which to use preferentially in predicting health outcomes. The study objective was to compare the ...

journal_title：BMJ open

authors： Wallace E,McDowell R,Bennett K,Fahey T,Smith SM

更新日期：2016-09-20 00:00:00

abstract：INTRODUCTION:The management of intra-articular chondral defects in the knee remains a challenge. Inadequate healing in areas of weight bearing leads to impairment in load transmission and these defects predispose to later development of osteoarthritis. Surgical management of full thickness chondral defects include arth...

journal_title：BMJ open

authors： Freitag J,Ford J,Bates D,Boyd R,Hahne A,Wang Y,Cicuttini F,Huguenin L,Norsworthy C,Shah K

更新日期：2015-12-18 00:00:00

abstract：OBJECTIVES:Intrinsic capacity (IC) was proposed by the WHO as a new concept for capturing an individual's functional capacities across their lifetime. We aimed to investigate the prevalence and factors associated with IC decline and examine associations between IC and adverse outcomes among community-dwelling older adu...

journal_title：BMJ open

authors： Ma L,Chhetri JK,Zhang L,Sun F,Li Y,Tang Z

更新日期：2021-01-05 00:00:00

abstract：OBJECTIVES:To investigate an association between fatty liver disease (FLD) and erosive oesophagitis. DESIGN AND SETTING:This was a cross-sectional study of subjects selected from examinees who underwent health check-up, including oesophagogastroduodenoscopy in one hospital between 2004 and 2011. Erosive oesophagitis w...

journal_title：BMJ open

authors： Choi JS,Kim HM,Yang YJ,Lee S,Jeong SH,Han KJ

更新日期：2019-01-30 00:00:00

abstract：CONTEXT AND OBJECTIVES:Neighbourhood effect research on obesity took off in the early 2000s and was composed of mostly cross-sectional observational studies interested in various characteristics of the built environment and the socioeconomic environment. To limit biases related to self-selection and life course exposur...

journal_title：BMJ open

authors： Letarte L,Pomerleau S,Tchernof A,Biertho L,Waygood EOD,Lebel A

更新日期：2020-03-25 00:00:00

abstract：INTRODUCTION:Cardiovascular disease (CVD) remains a major cause of morbidity and premature mortality globally. Despite the availability of low-cost evidence based medicines, there is a significant treatment gap in those with established or at high risk of CVD in the primary care setting. Pharmacist-based interventions ...

journal_title：BMJ open

authors： Chaudhri K,Hayek A,Liu H,Joshi R

更新日期：2019-08-05 00:00:00

abstract：OBJECTIVES:To determine whether there was variation in nurse staffing across hospitals in Queensland prior to implementation of nurse-to-patient ratio legislation targeting medical-surgical wards, and if so, the extent to which nurse staffing variation was associated with poor outcomes for patients and nurses. DESIGN:...

journal_title：BMJ open

authors： McHugh MD,Aiken LH,Windsor C,Douglas C,Yates P

更新日期：2020-09-06 00:00:00

abstract：OBJECTIVE:To investigate whether the daily workload per nurse (Oulu Patient Classification (OPCq)/nurse) as measured by the RAFAELA system correlates with different types of patient safety incidents and with patient mortality, and to compare the results with regressions based on the standard patients/nurse measure. SE...

journal_title：BMJ open

authors： Fagerström L,Kinnunen M,Saarela J

更新日期：2018-04-24 00:00:00

abstract：INTRODUCTION:Stroke is a major health problem and transient ischaemic attack (TIA) is an important risk factor for stroke. Primary prevention of stroke and TIA will have the greatest impact on reducing the burden of these conditions. Evidence-based guidelines for stroke/TIA prevention identify individuals eligible for ...

journal_title：BMJ open

authors： Moran GM,Calvert M,Feltham MG,Marshall T

更新日期：2014-11-11 00:00:00

abstract：INTRODUCTION:So-Cheong-Ryong-Tang (SCRT) is a herbal medicine widely used in traditional medicine for treating allergic rhinitis (AR). In animal studies, SCRT has suppressed the progression of AR. The main purpose of this study is to assess the efficacy and safety of the SCRT for the treatment of perennial allergic rhi...

journal_title：BMJ open

authors： Kim MH,Ko Y,Ahn JH,Yun Y,Yun MN,Ko SG,Choi I

更新日期：2017-09-27 00:00:00

abstract：INTRODUCTION:Although the colorectal cancer (CRC) mortality rate has significantly improved over the past several decades, many patients will have a recurrence following curative treatment. Despite this high risk of recurrence, adherence to CRC surveillance testing guidelines is poor which increases cancer-related morb...

journal_title：BMJ open

authors： Hines RB,Jiban MJH,Choudhury K,Loerzel V,Specogna AV,Troy SP,Zhang S

更新日期：2018-04-28 00:00:00

abstract：INTRODUCTION:Self-management and remaining physically active are first-line recommendations for the care of patients with low back pain (LBP). With a lifetime prevalence of up to 85%, novel approaches to support behavioural self-management are needed. Internet interventions may provide accessible support for self-manag...

journal_title：BMJ open

authors： Geraghty AWA,Roberts L,Hill J,Foster NE,Yardley L,Hay E,Stuart B,Turner D,Griffiths G,Webley F,Durcan L,Morgan A,Hughes S,Bathers S,Butler-Walley S,Wathall S,Mansell G,Leigh L,Little P

更新日期：2020-08-20 00:00:00

abstract：INTRODUCTION:The incidence of head and neck cancer (HNC) in the UK is rising, with an average of 31 people diagnosed daily. Patients affected by HNC suffer significant short-term and long-term post-treatment morbidity as a result of dysphagia, which affects daily functioning and quality of life (QOL). Pretreatment swal...

journal_title：BMJ open

authors： Govender R,Smith CH,Gardner B,Barratt H,Taylor SA

更新日期：2017-03-27 00:00:00

abstract：OBJECTIVES:The reliability of ultrasonic strain elastography (SEL) used to detect abnormalities in the supraspinatus tendon is unclear. Thus, the aim of this study was to investigate the reliability of SEL in the supraspinatus tendon. DESIGN:An intra-rater and inter-rater reliability study. SETTING:A single-centre st...

journal_title：BMJ open

authors： Brage K,Hjarbaek J,Kjaer P,Ingwersen KG,Juul-Kristensen B

更新日期：2019-05-09 00:00:00

abstract：OBJECTIVE:This paper explores what aspects of a multicomponent intervention were deemed strengths and weaknesses by teenagers and the local council when promoting physical activity to young people. DESIGN:Qualitative findings at 12 months from a mixed method randomised control trial. METHODS:Active Children Through I...

journal_title：BMJ open

authors： James M,Christian D,Scott S,Todd C,Stratton G,Demmler J,McCoubrey S,Halcox J,Audrey S,Ellins EA,Irvine E,Brophy S

更新日期：2019-05-10 00:00:00

abstract：INTRODUCTION:Recent evidence has implicated the precuneus of the medial parietal lobe as one of the first brain areas to show pathological changes in Alzheimer's disease (AD). Damage to the precuneus through focal brain injury is associated with impaired visually guided reaching, particularly for objects in peripheral ...

journal_title：BMJ open

authors： Mitchell AG,McIntosh RD,Rossit S,Hornberger M,Pal S

更新日期：2020-06-04 00:00:00