Abstract:
BACKGROUND:Autoimmune hepatitis causes chronic hepatitis and often leads to cirrhosis and death without treatment. We wanted to see if having access to primary care or insurance prior to diagnosis is associated with better outcomes for patients in an urban, public hospital with mostly socioeconomically disadvantaged Hispanic patients. METHODS:We did a retrospective study at our institution. Kaplan Meier survival analysis was done looking at transplant-free overall survival for patients diagnosed at our institution. The log-rank test was done to compare survival between patients with and without prior access to primary care, and between patients with and without insurance at diagnosis. RESULTS:Overall 5- and 10-year transplant-free overall survival was 91% (95% CI, 83-100%) and 75% (95% CI, 50-99%), respectively. Patients with primary care prior to diagnosis had significantly better transplant-free overall survival than those without (log rank test p = 0.019). Patients with primary care also had better clinical markers at diagnosis. Having insurance at diagnosis was not associated with better outcomes. CONCLUSIONS:Outcomes of autoimmune hepatitis are poor in our setting but access to primary care prior to diagnosis was associated with better outcomes. This is likely due to the important role that primary care plays in detecting disease and initiating treatment earlier. With the expansion of access to healthcare that the Affordable Care Act provides, future patients are likely to do better with even rare diseases like autoimmune hepatitis.
journal_name
BMC Gastroenteroljournal_title
BMC gastroenterologyauthors
Kim D,Eshtiaghpour D,Alpern J,Datta A,Eysselein VE,Yee HFdoi
10.1186/s12876-015-0318-ysubject
Has Abstractpub_date
2015-07-28 00:00:00pages
91issn
1471-230Xpii
10.1186/s12876-015-0318-yjournal_volume
15pub_type
杂志文章abstract:BACKGROUND:Rumination syndrome (RS) is a functional gastrointestinal disorder (FGD) increasingly recognized in children and adolescents. The epidemiology of this condition in school aged children is poorly understood. The main objective of this study was to assess the prevalence of rumination and other related associat...
journal_title:BMC gastroenterology
pub_type: 杂志文章
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abstract:BACKGROUND:Gastroparesis (Gp) is a poorly understood chronic gastrointestinal medical condition for which patient reported outcomes (PRO) are lacking. Previously developed symptoms scoring has been used for several decades. Using symptoms scores as a basis for documentation, 12 years of support/focus group patient feed...
journal_title:BMC gastroenterology
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doi:10.1186/s12876-016-0523-3
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abstract:BACKGROUND:Erdheim-Chester disease (ECD) is a rare multisystem non-Langerhans cell histiocytosis that is characterized histologically by xanthogranulomatous infiltrates and radiologically by symmetrical sclerosis of long bones. The xanthomatous process is characterized by prominent foamy histiocytes staining positive f...
journal_title:BMC gastroenterology
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-5-11
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journal_title:BMC gastroenterology
pub_type: 杂志文章
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abstract:BACKGROUND:Infliximab is usually administered by two monthly intravenous (iv) infusions, therefore requiring visits to hospital. Adalimumab is administered by self subcutaneous (sc) injections every other week. Both of these anti-TNF drugs appear to be equally efficacious in the treatment of Crohn's Disease and therefo...
journal_title:BMC gastroenterology
pub_type: 杂志文章
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更新日期:2010-01-10 00:00:00
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journal_title:BMC gastroenterology
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doi:10.1186/1471-230X-12-119
更新日期:2012-08-30 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01440-7
更新日期:2020-09-11 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-018-0899-3
更新日期:2018-11-12 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-12-48
更新日期:2012-05-14 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01352-6
更新日期:2020-06-29 00:00:00
abstract:BACKGROUND:This case seeks to highlight to endoscopists a rare benign disorder that may be encountered during endoscopy. Clinicians may be tempted to biopsy, which could lead to a catastrophic gastrointestinal haemorrhage. CASE PRESENTATION:A 66-year-old asymptomatic Caucasian male was referred for colonoscopy with a ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-019-1118-6
更新日期:2019-11-27 00:00:00
abstract:BACKGROUND:The search for better non-invasive biomarkers for gastric cancer remains ongoing. We investigated the predictive power of serum trefoil factor (TFF) levels as biomarkers for gastric cancer in comparison with the pepsinogen (PG) test. METHODS:Patients with gastric cancer, chronic atrophic gastritis (CAG) or ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-14-74
更新日期:2014-04-11 00:00:00
abstract:BACKGROUND:Cystic echinococcosis (CE) is one of emerging zoonotic parasitic diseases throughout the world, having significant medical and economic importance in developing countries. The western and northwestern China is considered as CE endemic areas. In northeastern China's Heilongjiang Province, the increasing numbe...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-015-0256-8
更新日期:2015-03-10 00:00:00
abstract:BACKGROUND:Chronic active Epstein-Barr virus infection (CAEBV) is defined as Epstein-Barr virus (EBV)-positive T/NK cell-related neoplasia, and its major clinical symptom is systemic inflammation presenting as infectious mononucleocytosis, whereas enteritis and diarrhea are minor clinical symptoms. The complex mixture ...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01589-1
更新日期:2021-01-06 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-018-0843-6
更新日期:2018-07-06 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01286-z
更新日期:2020-05-06 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01515-5
更新日期:2020-11-03 00:00:00
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pub_type: 杂志文章
doi:10.1186/1471-230X-10-137
更新日期:2010-11-20 00:00:00
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journal_title:BMC gastroenterology
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更新日期:2013-10-25 00:00:00
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更新日期:2020-07-29 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-015-0317-z
更新日期:2015-07-24 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12876-016-0472-x
更新日期:2016-06-04 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-020-01327-7
更新日期:2020-06-09 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-014-0211-0
更新日期:2014-12-10 00:00:00
abstract:BACKGROUND:Translocation of gut-derived bacterial products such as endotoxin is a major problem in liver cirrhosis. METHODS:To assess the hepatic clearance of bacterial products in individuals with cirrhosis, we tested concentrations of Gram-negative bacterial lipopolysaccharide (LPS), LPS-binding protein (LBP), and t...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-11-107
更新日期:2011-10-06 00:00:00
abstract:BACKGROUND:Distal diminutive colorectal polyps are common and accurate endoscopic prediction of hyperplastic or adenomatous polyp histology could reduce procedural time, costs and potential risks associated with the resection. Within this study we assessed whether digital chromoendoscopy can accurately predict the hist...
journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/s12876-015-0374-3
更新日期:2015-10-22 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-9-98
更新日期:2009-12-24 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-12-55
更新日期:2012-05-28 00:00:00
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journal_title:BMC gastroenterology
pub_type: 杂志文章
doi:10.1186/1471-230X-14-97
更新日期:2014-05-22 00:00:00