The overmethylated genes in Helicobacter pylori-infected gastric mucosa are demethylated in gastric cancers.

abstract：BACKGROUND:Adult lactase non-persistence (LNP) is due to low lactase expression, resulting in lactose malabsorption (LM). LNP is a genetic trait, but is typically determined by LM markers including breath H2, blood glucose, and urinary galactose after a lactose tolerance test. Known validity of these markers using milk...

journal_title：BMC gastroenterology

authors： Shrestha A,Barnett MPG,Perry JK,Cameron-Smith D,Milan AM

更新日期：2020-06-29 00:00:00

abstract：BACKGROUND:Intussusception (IS) is a form of acute intestinal obstruction that occurs mainly in infants and is usually of unknown cause. An association between IS and the first licensed rotavirus vaccine, a reassortant-tetravalent, rhesus-based rotavirus vaccine (RRV-TV), led to the withdrawal of the vaccine. New rotav...

journal_title：BMC gastroenterology

authors： Sáez-Llorens X,Velázquez FR,Lopez P,Espinoza F,Linhares AC,Abate H,Nuñez E,Venegas G,Vergara R,Jimenez AL,Rivera M,Aranza C,Richardson V,Macias-Parra M,Palacios GR,Rivera L,Ortega-Barria E,Cervantes Y,Rüttimann R,Ru

更新日期：2013-05-27 00:00:00

abstract：BACKGROUND:Partial External Biliary Diversion (PEBD) is a surgical intervention to treat children with Progressive Familial Intrahepatic Cholestasis (PFIC) and Alagille syndrome (AGS). PEBD can reduce disease progression, and examining the alterations in biliary lipid composition may be a prognostic factor for outcome....

journal_title：BMC gastroenterology

authors： Emerick KM,Elias MS,Melin-Aldana H,Strautnieks S,Thompson RJ,Bull LN,Knisely As,Whitington PF,Green RM

更新日期：2008-10-20 00:00:00

abstract：BACKGROUND:A validated histopathological tool to precisely evaluate bowel fibrosis in patients with Crohn's disease is lacking. We attempted to establish a new index to quantify the severity of bowel fibrosis in patients with Crohn's disease-associated fibrostenosis. METHODS:We analyzed the histopathological data of 3...

journal_title：BMC gastroenterology

authors： Li XH,Fang ZN,Guan TM,Lin JJ,Sun CH,Huang SY,Mao R,Lu BL,Cao QH,Feng ST,Li ZP

更新日期：2019-11-11 00:00:00

abstract：BACKGROUND:The elderly population presents higher morbidity of H. pylori associated diseases in proximal stomach. The specific pathogenesis and mechanism have not been clearly addressed. The gastric environment for H. pylori colonization is dynamic with increasing age. The aim of present study is to investigate the cor...

journal_title：BMC gastroenterology

authors： Shi H,Xiong H,Qian W,Lin R

更新日期：2018-10-29 00:00:00

abstract：BACKGROUND:This study investigated a possible role of Escherichia coli in propagation and perpetuation of the chronic inflammation in ulcerative colitis (UC). The lesions of UC are located superficially on the rectal and/or colonic mucosa. It is suggested that the commensal bacteria of the digestive tract may play a ro...

journal_title：BMC gastroenterology

authors： Pilarczyk-Zurek M,Chmielarczyk A,Gosiewski T,Tomusiak A,Adamski P,Zwolinska-Wcislo M,Mach T,Heczko PB,Strus M

更新日期：2013-04-08 00:00:00

abstract：BACKGROUND:From the morphological appearance, it was impossible to distinguish terminal portal venules from small lymphatic vessels in the portal tract even using histochemical microscopic techniques. Recently, D2-40 was found to be expressed at a high level in lymphatic endothelial cells (LECs). This study was underta...

journal_title：BMC gastroenterology

authors： Yokomori H,Oda M,Kaneko F,Kawachi S,Tanabe M,Yoshimura K,Kitagawa Y,Hibi T

更新日期：2010-11-08 00:00:00

abstract：BACKGROUND:To exam the biochemical, obstetric management and pregnancy outcome in women with intrahepatic cholestasis of pregnancy (ICP) and treatment with ursodeoxycholic acid (UDCA). METHODS:Pregnancy outcome in patients with ICP (N = 307) was studied and patients treated with UDCA (N = 208) vs. no UDCA were compare...

journal_title：BMC gastroenterology

authors： Joutsiniemi T,Timonen S,Linden M,Suvitie P,Ekblad U

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:Feeding related peptides have been shown to be additionally involved in the central autonomic control of gastrointestinal functions. Recent studies have shown that ghrelin, a stomach-derived orexigenic peptide, is involved in the autonomic regulation of GI function besides feeding behavior. Pharmacological e...

journal_title：BMC gastroenterology

authors： Tebbe JJ,Tebbe CG,Mronga S,Ritter M,Schäfer MK

更新日期：2005-02-18 00:00:00

abstract：BACKGROUND:The occurrence of non-alcoholic fatty liver disease (NAFLD) is found to be higher in patients with obstructive sleep apnea (OSA), which is characterized by intermittent hypoxia. Activation of hypoxia-inducible factors has been shown in the development and progression of NAFLD, implying a cause and effects re...

journal_title：BMC gastroenterology

authors： Zhang X,Huang C,Li X,Shangguan Z,Wei W,Liu S,Yang S,Liu Y

更新日期：2020-11-03 00:00:00

abstract：BACKGROUND:Irritable Bowel Syndrome (IBS) is a common chronic gastrointestinal disorder and the evidence for efficacy of most drug therapies in the treatment of IBS is weak. A popular alternative is probiotics, which have been used in several conditions. including IBS. Probiotics are live microbial food supplements.The...

journal_title：BMC gastroenterology

authors： Hoveyda N,Heneghan C,Mahtani KR,Perera R,Roberts N,Glasziou P

更新日期：2009-02-16 00:00:00

abstract：BACKGROUND:Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm that originates from follicular dendritic cells in lymphoid tissue while paraneoplastic pemphigus (PNP) is an autoimmune blistering disease associated with neoplasms. Pancreatic FDCS associated with PNP and myasthenia gravis (MG) is even rarer and h...

journal_title：BMC gastroenterology

authors： Lu T,Song B,Pu H,Li X,Chen Q,Yang C

更新日期：2019-06-14 00:00:00

abstract：BACKGROUNDS:Nonalcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease in Asians. However, data on prevalence and factors associated with NAFLD in Asians are lacking. The aim of this study is to investigate the prevalence of NAFLD in Shanghai employees to assess the relationship between N...

journal_title：BMC gastroenterology

authors： Hu X,Huang Y,Bao Z,Wang Y,Shi D,Liu F,Gao Z,Yu X

更新日期：2012-09-14 00:00:00

abstract：BACKGROUND:Acetaminophen (APAP) overdose induces massive hepatocyte necrosis. Necrotic tissue releases high mobility group B1 (HMGB1), and HMGB1 contributes to liver injury. Even though blockade of HMGB1 does not protect against APAP-induced acute liver injury (ALI) at 9 h time point, the later time points are not stud...

journal_title：BMC gastroenterology

authors： Yang R,Zhang S,Cotoia A,Oksala N,Zhu S,Tenhunen J

更新日期：2012-05-08 00:00:00

abstract：BACKGROUND:Percutaneous Endoscopic Gastrostomy (PEG) feeding tubes are frequently placed in patients to provide enteral nutrition. We report a case of a complete rupture of a PEG tube intra-abdominally with associated peritonitis after more than a month of PEG placement and utilization. To our knowledge, this is a very...

journal_title：BMC gastroenterology

authors： Al Halabi M,Wakim W,Moukaddam H,Husari A

更新日期：2020-03-30 00:00:00

abstract：BACKGROUND:The gastric microbiota has recently been implicated in the causation of organic/structural gastroduodenal diseases (gastric and duodenal ulcers, gastric cancer) in patients with Helicobacter pylori (H. pylori) infection. We aimed to ascertain, in patients harbouring H. pylori, the role of the gastric microbi...

journal_title：BMC gastroenterology

authors： Pereira V,Abraham P,Nallapeta S,Shetty A

更新日期：2018-01-26 00:00:00

abstract：BACKGROUND:Studies have demonstrated usefulness of cognitive-behavioural therapy (CBT) in managing distress in inflammatory bowel disease (IBD); however, few have focused on IBD course. The present trial aimed to investigate whether adding CBT to standard treatment prolongs remission in IBD in comparison to standard th...

journal_title：BMC gastroenterology

authors： Mikocka-Walus A,Bampton P,Hetzel D,Hughes P,Esterman A,Andrews JM

更新日期：2015-05-02 00:00:00

abstract：BACKGROUND:A large-scale Japanese study showed that low skeletal muscle index (SMI) and intramuscular fat (IMF) deposition are associated with hepatocellular carcinoma (HCC) survival. Here, we evaluated the effects of SMI and IMF on the survival of Indonesian HCC patients, whose characteristics differ from those of Jap...

journal_title：BMC gastroenterology

authors： Mardian Y,Yano Y,Ratnasari N,Choridah L,Wasityastuti W,Setyawan NH,Hayashi Y

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:Enteric glia cells (EGC) play an important role in the maintenance of intestinal mucosa integrity. During the course of acute Crohn's disease (CD), mucosal EGC progressively undergo apoptosis, though the mechanisms are largely unknown. We investigated the role of Glial-derived neurotrophic factor (GDNF) in t...

journal_title：BMC gastroenterology

authors： Steinkamp M,Gundel H,Schulte N,Spaniol U,Pflueger C,Zizer E,von Boyen GB

更新日期：2012-01-17 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) is mutually and bidirectionally linked with metabolic syndrome (MetS) of which it is both the cause and the consequences. Worldwide, 6.3 to 33% of the general populations are estimated to suffer from the disease with even higher prevalence in the group sharing metabo...

journal_title：BMC gastroenterology

authors： Pardhe BD,Shakya S,Bhetwal A,Mathias J,Khanal PR,Pandit R,Shakya J,Joshi HO,Marahatta SB

更新日期：2018-07-06 00:00:00

abstract：BACKGROUND:Pancreas divisum, the most common congenital anomaly of the pancreas, is caused by failure of the fusion of the ventral and dorsal pancreatic duct systems during embryological development. Although various pancreatic tumors can occur in patients with pancreas divisum, intraductal papillary mucinous neoplasm ...

journal_title：BMC gastroenterology

authors： Nishi T,Kawabata Y,Ishikawa N,Araki A,Yano S,Maruyama R,Tajima Y

更新日期：2015-07-08 00:00:00

abstract：BACKGROUND:Transient elastography (TE) is an innovative, noninvasive technique to assess liver fibrosis by measuring liver stiffness in patients with chronic liver diseases. The purpose of this study has been to explore the accuracy of TE and clinical parameters in predicting the presence of esophageal/gastric varices ...

journal_title：BMC gastroenterology

authors： Chongsrisawat V,Vejapipat P,Siripon N,Poovorawan Y

更新日期：2011-04-18 00:00:00

abstract：BACKGROUND:Chronic active Epstein-Barr virus infection (CAEBV) is defined as Epstein-Barr virus (EBV)-positive T/NK cell-related neoplasia, and its major clinical symptom is systemic inflammation presenting as infectious mononucleocytosis, whereas enteritis and diarrhea are minor clinical symptoms. The complex mixture ...

journal_title：BMC gastroenterology

authors： Aihara Y,Moriya K,Shimozato N,Nagamatsu S,Kobayashi S,Uejima M,Matsuo H,Ishida E,Yagi H,Nakatani T,Yoshiji H,Kikuchi E

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:Cystic echinococcosis (CE) is one of emerging zoonotic parasitic diseases throughout the world, having significant medical and economic importance in developing countries. The western and northwestern China is considered as CE endemic areas. In northeastern China's Heilongjiang Province, the increasing numbe...

journal_title：BMC gastroenterology

authors： Zhang T,Zhao W,Yang D,Piao D,Huang S,Mi Y,Zhao X,Cao J,Shen Y,Zhang W,Liu A

更新日期：2015-03-10 00:00:00

abstract：BACKGROUND:Microcirculatory disturbance is an important factor in the pathogenesis of Inflammatory Bowel Disease (IBD) but there have been few studies in this field. Confocal Laser Endomicroscopy (CLE) has been used over the last 10 years and has made it possible to explore the changes in microcirculation of the coloni...

journal_title：BMC gastroenterology

authors： Tian Y,Zheng Y,Teng G,Li J,Wang H

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:The emergence of multidrug-resistant (MDR) Escherichia coli (E. coli), particularly E. coli sequence type ST131, is becoming a global concern. Commensal bacteria, an important reservoir of antibiotic resistance genes, facilitate the spread of such genes to pathogenic bacterial strains. The objective of the s...

journal_title：BMC gastroenterology

authors： Huang IF,Lee WY,Wang JL,Hung CH,Hu HH,Hung WY,Hung YJ,Chen WC,Shen YT,Cheng MF

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:Alpha-fetoprotein (AFP)-producing pancreatic neuroendocrine tumors (pNETs) are rare, and the few reported cases usually coexisted with other malignant components such as adenocarcinoma or hepatoid carcinoma. We present here the first case of pure AFP-producing pNET. CASE PRESENTATION:A 56-year-old male pati...

journal_title：BMC gastroenterology

authors： Zhu X,Yong H,Zhang L,Huang Y,Zheng J,Liu C,Xiu D,Zhang P

更新日期：2015-02-12 00:00:00

abstract：BACKGROUND:Benign biliary strictures may be a consequence of surgical procedures, chronic pancreatitis or iatrogenic injuries to the ampulla. Stents are increasingly being used for this indication, however it is not completely clear which stent type should be preferred. METHODS:A systematic review on stent placement f...

journal_title：BMC gastroenterology

authors： van Boeckel PG,Vleggaar FP,Siersema PD

更新日期：2009-12-17 00:00:00

abstract：BACKGROUND:Saturated fatty acids are thought to be of relevance for the development of non-alcoholic fatty liver disease and obesity. However, the underlying mechanisms are poorly understood. In previous studies we found that food-derived carbohydrates such as fructose alter the intestinal serotonergic system while ind...

journal_title：BMC gastroenterology

authors： Ritze Y,Böhle M,Haub S,Hubert A,Enck P,Zipfel S,Bischoff SC

更新日期：2013-12-09 00:00:00

abstract：BACKGROUND:Gastric cancer can progress from a chronic inflammation of the gastric mucosa resulting from Helicobacter pylori infection that activates the inflammatory response of the host. Therefore, polymorphisms in genes involved in the inflammatory response, such as inducible nitric oxide synthase (NOS2), have been i...

journal_title：BMC gastroenterology

authors： Jorge YC,Duarte MC,Silva AE

更新日期：2010-06-17 00:00:00