Abstract：
:We have developed a treatment planning protocol for intensity-modulated radiation therapy of the prostate using commercially available inverse planning software. Treatment plans were developed for ten patients using the Corvus version 3.8 planning system, testing various prescription options, including tissue types, dose volume histogram values for the target and normal structures, beam arrangements, and number of intensity levels. All plans were scaled so that 95% of the clinical target volume received 75.6 Gy; mean doses to the prostate were typically 79 Gy. The reproducibility of the inverse planning algorithm was tested by repeating a set of the plans five times. Plans were deemed acceptable if they satisfied predefined dose constraints for the targets and critical organs. Figures of merit for target coverage, target dose uniformity, and organ sparing were used to rank acceptable plans. Certain systematic behaviors of the optimizer were noted: the high dose regions for both targets and critical organs were 5-10 Gy more than prescribed; reducing bladder and rectum tolerance increased the range of doses within the target; increasing the number of fields incrementally improved plan quality. A set of planning parameters was found that usually satisfied the minimum requirements. Repeating the optimization with different beam order produced similar but slightly different dose distributions, which was sometimes useful for finding acceptable solutions for difficult cases. The standard set of parameters serves as a useful starting point for individualized planning.
journal_name
J Appl Clin Med Physjournal_title
Journal of applied clinical medical physicsauthors
Ezzell GA,Schild SE,Wong WWdoi
10.1120/jacmp.v2i2.2614keywords:
subject
Has Abstractpub_date
2001-04-01 00:00:00pages
59-68issue
2issn
1526-9914journal_volume
2pub_type
临床试验,杂志文章abstract：:The aim of this work is to evaluate the performance of a commercial brachytherapy treatment planning system (TPS) with TG-43 Vendors Input Data (VID), analyze possible discrepancies with respect to a proper reference source and its implications for standard treatments, and judge the effectiveness of certain widespread...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v16i4.4730
更新日期：2015-07-08 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12991
更新日期：2020-09-01 00:00:00
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doi：10.1120/jacmp.v16i5.5057
更新日期：2015-09-08 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v1i4.2636
更新日期：2000-10-01 00:00:00
abstract：:In order to locate lung tumors on kV projection images without internal markers, digitally reconstructed radiographs (DRRs) are created and compared with projection images. However, lung tumors always move due to respiration and their locations change on projection images while they are static on DRRs. In addition, gl...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v16i3.5200
更新日期：2015-05-08 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v16i6.5793
更新日期：2015-11-08 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v13i6.3981
更新日期：2012-11-08 00:00:00
abstract：:The purpose of this study was to assess treatment margins in free-breathing irradiation of pancreatic cancer after bone alignment, and evaluate their impact on conformal radiotherapy. Fifteen patients with adenocarcinoma of the head of the pancreas underwent implantation of single fiducial marker. Intrafraction uncert...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v14i4.4152
更新日期：2013-07-08 00:00:00
abstract：:This work describes the use of 3D printing technology to create individualized boluses for patients treated with electron beam therapy for skin lesions of the eye canthi. It aimed to demonstrate the effectiveness of 3D-printed over manually fabricated paraffin boluses. The study involved 11 patients for whom the const...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12013
更新日期：2017-01-01 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.13041
更新日期：2020-10-12 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v15i1.4600
更新日期：2014-01-06 00:00:00
abstract：PURPOSE:We report the first cervical cancer cases treated with interstitial electronic brachytherapy (eBT) at our hospital and compare them with plans made with high-dose-rate interstitial brachytherapy based on Ir192 (HDR-BT). MATERIALS AND METHODS:Eight patients with cervical cancer were treated with the Axxent eBT ...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12657
更新日期：2019-07-01 00:00:00
abstract：:A patient specific quality assurance (QA) should detect errors that originate anywhere in the treatment planning process. However, the increasing complexity of treatment plans has increased the need for improvements in the accuracy of the patient specific pretreatment verification process. This has led to the utilizat...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12114
更新日期：2017-07-01 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12919
更新日期：2020-08-01 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.13057
更新日期：2020-11-03 00:00:00
abstract：:Stereotactic body radiation therapy (SBRT) has been increasingly used as an efficacious treatment modality for early-stage non-small cell lung cancer. The accuracy of dose calculations is compromised due to the presence of inhomogeneity. For the purpose of a consistent prescription, radiation doses were calculated wit...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v14i2.4011
更新日期：2013-03-04 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v12i4.3447
更新日期：2011-11-15 00:00:00
abstract：:Small field dosimetry is a challenging task. The difficulties of small field measurements, particularly stereotactic field size measurements, are highlighted by the large interinstitution variability that can be observed for circular cone collimator commissioning measurements. We believe the best way to improve the co...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v14i6.4493
更新日期：2013-11-04 00:00:00
abstract：:Performing a procedure on the wrong patient or site is one of the greatest errors that can occur in medicine. The addition of automation has been shown to reduce errors in many processes. In this work we explore the use of an automated patient identification process using optical surface imaging for radiotherapy treat...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v17i2.6066
更新日期：2016-03-08 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12227
更新日期：2018-01-01 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v12i2.3357
更新日期：2011-01-31 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
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更新日期：2010-10-04 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
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更新日期：2019-08-01 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v15i1.4517
更新日期：2014-01-06 00:00:00
abstract：:High dose rate (HDR) brachytherapy often involves optimization routines to calculate the dwell times and positions of a radioactive source along specified applicator paths. These routines optimize the dwells in such a way as to deliver the prescribed dose at one or more points while satisfying various constraints. The...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v4i2.2530
更新日期：2003-04-01 00:00:00
abstract：:Traditional quality assurance checks of a patient's radiation therapy plan involve printing out treatment parameters from the treatment planning system and the "record and verify" (R&V) system and visually checking the information for one-to-one correspondence. In a paperless environment, one can automate this process...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v10i1.2905
更新日期：2009-01-27 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v8i4.2439
更新日期：2007-09-24 00:00:00
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journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12567
更新日期：2019-04-01 00:00:00
abstract：:TomoEDGE is an advanced delivery form of tomotherapy which uses a dynamic secondary collimator. This plan comparison study describes the new features, their clinical applicability, and their effect on plan quality and treatment speed. For the first 45 patients worldwide that were scheduled for a treatment with TomoEdg...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
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更新日期：2015-03-08 00:00:00
abstract：:A new method of generating wedge-shaped dose distributions through dynamic multileaf collimator dose delivery rather than computer-controlled jaw motion is presented. The method starts with the calculation of a wedge-shaped beam profile for the desired wedge angle. The resultant wedge beam profile is then passed to th...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v6i3.2060
更新日期：2005-07-01 00:00:00
