Abstract：
:TomoEDGE is an advanced delivery form of tomotherapy which uses a dynamic secondary collimator. This plan comparison study describes the new features, their clinical applicability, and their effect on plan quality and treatment speed. For the first 45 patients worldwide that were scheduled for a treatment with TomoEdge, at least two plans were created: one with the previous "standard"mode with static jaws and 2.5 cm field width (Reg 2.5) and one with TomoEdge technique and 5 cm field width (Edge 5). If, after analysis in terms of beam on time, integral dose, dose conformity, and organ at risk sparing the treating physician decided that the Edge 5 plan was not suitable for clinical treatment, a plan with TomoEdge and 2.5 cm field width was created (Edge 2.5) and used for the treatment. Among the 45 cases, 30 were suitable for Edge 5 treatment, including treatments of the head and neck, rectal cancer, anal cancer, malignancies of the chest, breast cancer, and palliative treatments. In these cases, the use of a 5 cm field width reduced beam on time by more than 30% without compromising plan quality. The 5 cm beam could not be clinically applied to treatments of the pelvic lymph nodes for prostate cancer and to head and neck irradiations with extensive involvement of the skull, as dose to critical organs at risk such as bladder (average dose 28 Gy vs. 29 Gy, Reg 2.5 vs. Edge 5), small bowel (29% vs. 31%, Reg 2.5 vs. Edge 5) and brain (average dose partial brain 19 Gy vs. 21 Gy, Reg 2.5 vs. Edge 5) increased to a clinically relevant, yet not statistically significant, amount. TomoEdge is an advantageous extension of the tomotherapy technique that can speed up treatments and thus increase patient comfort and safety in the majority of clinical settings.
journal_name
J Appl Clin Med Physjournal_title
Journal of applied clinical medical physicsauthors
Katayama S,Haefner MF,Mohr A,Schubert K,Oetzel D,Debus J,Sterzing Fdoi
10.1120/jacmp.v16i2.4964subject
Has Abstractpub_date
2015-03-08 00:00:00pages
4964issue
2issn
1526-9914journal_volume
16pub_type
杂志文章abstract：:Stereotactic body radiotherapy (SBRT) of lung tumors via the ring-mounted Halcyon Linac, a fast kilovoltage cone beam CT-guided treatment with coplanar geometry, a single energy 6MV flattening filter free (FFF) beam and volumetric modulated arc therapy (VMAT) is a fast, safe, and feasible treatment modality for select...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.13146
更新日期：2020-12-20 00:00:00
abstract：PURPOSE:To investigate the effect of the marker placement on the correlation relationship between the motions of external markers and the internal target under different breathing patterns for several lung cancer patients. METHOD AND MATERIAL:To monitor and record simultaneous motions of internal target and associated...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v9i2.2758
更新日期：2008-04-16 00:00:00
abstract：PURPOSE:Multiple metrics are proposed to characterize and compare the complexity of helical tomotherapy (HT) plans created for different treatment sites. METHODS:A cohort composed of 208 HT plans from head and neck (105), prostate (51) and brain (52) tumor sites was considered. For each plan, 14 complexity metrics wer...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12895
更新日期：2020-07-01 00:00:00
abstract：:This study aims to evaluate the potential jaw-tracking advantage using control point sequences of volume volumetric modulated arc therapy (VMAT) planning. VMAT plans for patients with prostate and head and neck (H&N) cancers were converted into new static arc (SA) plans. The SA plan consisted of a series of static fie...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v15i2.4625
更新日期：2014-03-06 00:00:00
abstract：:This study extends the 'zero scan' method for CT imaging of polymer gel dosimeters to include multislice acquisitions. Multislice CT images consisting of 24 slices of 1.2 mm thickness were acquired of an irradiated polymer gel dosimeter and processed with the zero scan technique. The results demonstrate that zero scan...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v15i4.4360
更新日期：2014-07-08 00:00:00
abstract：:The aim of this study was to report a single-institution experience and commissioning data for Elekta VersaHD linear accelerators (LINACs) for photon beams in the Eclipse treatment planning system (TPS). Two VersaHD LINACs equipped with 160-leaf collimators were commissioned. For each energy, the percent-depth-dose (P...
journal_title：Journal of applied clinical medical physics
pub_type： 临床试验,杂志文章
doi：10.1002/acm2.12709
更新日期：2019-10-01 00:00:00
abstract：:The nonphysical wedge is a modality that uses computer-controlled jaw motion to generate wedge-shaped dose distributions. There are Varian enhanced dynamic wedges (EDWs) and Siemens virtual wedges (VWs). We recently commissioned dynamic wedges on both Varian and Siemens LINACs. The beam data, acquired with a Wellhofer...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v5i4.1964
更新日期：2004-10-01 00:00:00
abstract：:This article compares two algorithms for determining beam weights and wedge filters for conformal treatment planning. One algorithm, which is based on dose-gradient analysis, provides analytic formulas for determining beam weights, wedge angles, and collimator angles (i.e., wedge orientations) so that the dose distrib...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v3i3.2562
更新日期：2002-07-01 00:00:00
abstract：:Shewhart control charts have previously been suggested as a process control tool for use in routine linear accelerator (linac) output verifications. However, a comprehensive approach to process control has not been investigated for linac output verifications. The purpose of this work is to investigate a comprehensive ...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v14i1.4032
更新日期：2013-01-07 00:00:00
abstract：:The study purpose was to develop and validate a quality assurance test for CT automatic exposure control (AEC) systems based on a set of nested polymethylmethacrylate CTDI phantoms. The test phantom was created by offsetting the 16 cm head phantom within the 32 cm body annulus, thus creating a three part phantom. This...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v17i4.6165
更新日期：2016-07-08 00:00:00
abstract：:Intra-fraction organ motion during the dynamic delivery of IMRT treatment of lung tumors may cause unexpected hot/cold spots even within the target volume, due to the interplay effect between tumor motion and multi-leaf collimator (MLC) leaf motion. In the past, this has been investigated through theoretical analysis,...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v7i4.2222
更新日期：2006-11-28 00:00:00
abstract：:The purpose of this study was to evaluate the dose differences introduced by the TMR 10 and the convolution dose calculation algorithms in GammaPlan version 10, as compared to the TMR classic algorithm in the previous versions of GammaPlan. Computed axial tomographic images of a polystyrene phantom and a human head we...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v15i5.4844
更新日期：2014-09-08 00:00:00
abstract：:This paper investigates the accuracy of the two available calculation algorithms of the Oncentra MasterPlan three-dimensional treatment planning system (TPS)-- the pencil beam method and collapsed-cone convolution--in modeling the Varian enhanced dynamic wedge (EDW). Measurements were carried out for a dual high energ...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v10i2.2867
更新日期：2009-04-22 00:00:00
abstract：:Varian (Palo Alto, California, United States) recently released an online adaptation treatment platform, Ethos, which has introduced a new Dose Preview and Automated Plan Generation module despite sharing identical beam data with the existing Halcyon linac. The module incorporates a preconfigured beam model and the Ac...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.13056
更新日期：2020-12-01 00:00:00
abstract：:Highly attenuating radiation treatment couches are no longer useful in the present era of radiotherapy utilizing IMRT and IGRT. Carbon fibers couch tops with its high tensile strength and low density present a useful alternative. The objective of the current study was to quantify the attenuation of megavoltage photons...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v10i3.2979
更新日期：2009-06-02 00:00:00
abstract：:The goal of this study was to investigate small field output factors (OFs) for flat-tening filter-free (FFF) beams on a dedicated stereotactic linear accelerator-based system. From this data, the collimator exchange effect was quantified, and detector-specific correction factors were generated. Output factors for 16 j...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v17i6.6433
更新日期：2016-11-08 00:00:00
abstract：:The management of a pregnant patient in radiation oncology is an infrequent event requiring careful consideration by both the physician and physicist. The aim of this manuscript was to highlight treatment planning techniques and detail measurements of fetal dose for a pregnant patient recently requiring treatment for ...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12262
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVES:To compare the effectiveness of two different patient size metrics based on water equivalent diameter (Dw ), the mid-scan water equivalent diameter Dw_c , and the mean (average) water equivalent diameter in the imaged region, Dw_ave , for automatic detection of accidental changes in computed tomography (CT) ...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12240
更新日期：2018-01-01 00:00:00
abstract：PURPOSE:Volumetric modulated arc therapy (VMAT) is gaining popularity for stereotactic treatment of lung lesions for medically inoperable patients. Due to multiple beamlets in delivery of highly modulated VMAT plans, there are dose delivery uncertainties associated with small-field dosimetry error and interplay effects...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12878
更新日期：2020-07-01 00:00:00
abstract：:We assessed interfraction positional variation in pancreatic tumors using daily breath-hold cone-beam computed tomography at end-exhalation (EE) with visual feedback (BH-CBCT). Eleven consecutive patients with pancreatic cancer who underwent BH intensity-modulated radiation therapy with visual feedback were enrolled. ...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v16i2.5123
更新日期：2015-03-08 00:00:00
abstract：:The aim of this study was to compare image noise properties of GE Discovery HD 750 and Toshiba Aquilion ONE. The uniformity section of a Catphan 600 image quality assurance phantom was scanned with both scanners, at different dose levels and with extension rings simulating patients of different sizes. 36 datasets were...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v17i3.5900
更新日期：2016-05-08 00:00:00
abstract：:The purpose of this study was to quantify the intrafraction motion of pediatric patients with brain tumors during radiation therapy and investigate any correlation between motion, use of general anesthesia, and daily treatment duration. 100 pediatric patients with a mean age of 8.5 years (range: 1.0 to 17.8) were incl...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v12i4.3609
更新日期：2011-11-15 00:00:00
abstract：:This study evaluated the extent of improvement in dose predication accuracy achieved by the Fast Monte Carlo algorithm (MC) compared to the Ray Tracing algorithm (RAT) in stereotactic body radiotherapy (SBRT) of non-small cell lung cancer (NSCLC), and how their differences were influenced by the tumor site and size. T...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v14i5.4280
更新日期：2013-09-06 00:00:00
abstract：:Recently, specific computed tomography (CT) scanners have been equipped with organ-based tube current modulation (TCM) technology. It is possible that organ-based TCM will replace the conventional dose-reduction technique of reducing the effective milliampere-second. The aim of this study was to determine if organ-bas...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v13i2.3731
更新日期：2012-03-08 00:00:00
abstract：:This study evaluated the basic dosimetric characteristics of a Dynamic Multi Leaf Collimator (DMLC) using a diode detector and film measurements for Intensity Modulated Radiation Therapy Quality Assurance (IMRT QA). The EGSnrc Monte Carlo (MC) simulation system was used for the determination of MLC characteristics. Ra...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12055
更新日期：2017-03-01 00:00:00
abstract：:The image-guided radiotherapy technique (IGRT) makes use of imaging devices to verify the positions of the target volume and organs at risk during the treatment sessions. In this work we evaluate the image quality provided by an imaging system based on a kilovoltage cone-beam CT, and explore its ability to perform IGR...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1120/jacmp.v14i1.3888
更新日期：2013-01-07 00:00:00
abstract：OBJECTIVE:To evaluate the accuracy of a deep learning-based auto-segmentation mode to that of manual contouring by one medical resident, where both entities tried to mimic the delineation "habits" of the same clinical senior physician. METHODS:This study included 125 cervical cancer patients whose clinical target volu...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.13097
更新日期：2020-12-01 00:00:00
abstract：:A Histogram Analysis in Radiation Therapy (HART) program was primarily developed to increase the efficiency and accuracy of dose-volume histogram (DVH) analysis of large quantities of patient data in radiation therapy research. The program was written in MATLAB to analyze patient plans exported from the treatment plan...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：
更新日期：2010-01-28 00:00:00
abstract：:Longitudinal partial volume effects (z-axial PVE), which occur when an object partly occupies a slice, degrade image resolution and contrast in computed tomography (CT). Z-axial PVE is unavoidable for subslice objects and reduces their contrast according to their fraction contained within the slice. This effect can be...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.12005
更新日期：2017-01-01 00:00:00
abstract：INTRODUCTION:Increased modulation and dynamical delivery of external beam radiotherapy (EBRT), such as volumetric modulated arc therapy (VMAT) with dynamic gantry rotation, continuously variable dose rate (CVDR) and field shapes that change during the beam, place greater demands on the performance of linear accelerator...
journal_title：Journal of applied clinical medical physics
pub_type： 杂志文章
doi：10.1002/acm2.13047
更新日期：2020-10-23 00:00:00
