Abstract:
PURPOSE:We report the first cervical cancer cases treated with interstitial electronic brachytherapy (eBT) at our hospital and compare them with plans made with high-dose-rate interstitial brachytherapy based on Ir192 (HDR-BT). MATERIALS AND METHODS:Eight patients with cervical cancer were treated with the Axxent eBT device (Xoft, Inc.). Planning was with magnetic resonance imaging and computed tomography following the recommendations of the EMBRACE protocol. The dosimetry parameters of organs at risk (OAR) were evaluated for the bladder, rectum, and sigmoid colon (D2cc, D1cc, and D0.1cc). In addition, the V150 and V200 of irradiated tissue were compared for both eBT and HDR-BT. All patients received intensity-modulated external beam radiation therapy with a regimen of 23 sessions of 2 Gy followed by four sessions of 7 Gy of eBT performed over 2 weeks (two sessions followed by another two sessions a week later) following the EMBRACE recommendations. Each of the eight patients was followed to assess acute toxicity associated with treatment. RESULTS:The doses reaching OAR for eBT plans were lower than for HDR-BT plans. As for acute toxicity associated with eBT, very few cases of mucositis were detected. No cases of rectal toxicity and one case with grade 1 urinary toxicity were detected. The results at 1 month are equally good, and no relapses have occurred to date. CONCLUSIONS:The first results of treatment with the Axxent eBT device are promising, as no recurrences have been observed and toxicity is very low. eBT is a good alternative for treating cervical cancer in centers without access to conventional HDR.
journal_name
J Appl Clin Med Physjournal_title
Journal of applied clinical medical physicsauthors
Lozares-Cordero S,Font-Gómez JA,Gandía-Martínez A,Miranda-Burgos A,Méndez-Villamón A,Villa-Gazulla D,Alba-Escorihuela V,Jiménez-Puertas S,González-Pérez Vdoi
10.1002/acm2.12657subject
Has Abstractpub_date
2019-07-01 00:00:00pages
78-86issue
7issn
1526-9914journal_volume
20pub_type
杂志文章abstract::This work illustrates a procedure to assess the overall accuracy associated with Gamma Knife treatment planning using plugging. The main role of source plugging or blocking is to create dose falloff in the junction between a target and a critical structure. We report the use of MAGAT gel dosimeter for verification of ...
journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v13i6.3877
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
doi:10.1120/jacmp.v17i1.5792
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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更新日期:2003-04-01 00:00:00
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journal_title:Journal of applied clinical medical physics
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更新日期:2020-12-05 00:00:00
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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更新日期:2000-10-01 00:00:00
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journal_title:Journal of applied clinical medical physics
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更新日期:2020-10-01 00:00:00
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
pub_type: 杂志文章
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journal_title:Journal of applied clinical medical physics
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更新日期:2018-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Along with the increasing demand for high-quality radiotherapy and the growing number of high-precision radiotherapy devices, precise radiotherapy workflow management and accurate time evaluation of the entire radiotherapy process are crucial to providing appropriate, timely treatment for cancer ...
journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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journal_title:Journal of applied clinical medical physics
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更新日期:2017-01-01 00:00:00