Abstract:
:Pancreatic tumors are rich in immune cell infiltrates that include CD4+ T-cell subsets encompassing both regulatory T cells and TH17 cells. Rather than protecting the organism by exerting an anticancer effect, these T-cell subsets promote tumor formation. Thus, re-activation of antitumor immunity should be investigated for use in pancreatic cancer prevention and therapy.
journal_name
Oncoimmunologyjournal_title
Oncoimmunologyauthors
Zhang Y,McAllister F,Pasca di Magliano Mdoi
10.4161/onci.29125subject
Has Abstractpub_date
2014-06-05 00:00:00pages
e29125eissn
2162-4011issn
2162-402Xpii
2014ONCOIMM0124journal_volume
3pub_type
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