Abstract:
:We have developed a highly versatile platform for the systematic retrieval of T-cell receptors (TCRs) from single-antigen-reactive T cells and for characterization of their function and specificity. This approach enables rapid extraction of multiple TCRs from repertoires in individuals and not only broadens the diversity of TCRs suitable for clinical use, but also sets the stage for actively personalized immunotherapeutic strategies.
journal_name
Oncoimmunologyjournal_title
Oncoimmunologyauthors
Omokoko T,Simon P,Türeci Ö,Sahin Udoi
10.1080/2162402X.2015.1005523subject
Has Abstractpub_date
2015-03-19 00:00:00pages
e1005523issue
7eissn
2162-4011issn
2162-402Xpii
1005523journal_volume
4pub_type
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