Abstract:
:Recent findings from our laboratory provide the first indication that overexpression of Bcl-2 in Eµ-myc transgenic cells enhances tumor immunosurveillance by inducing NKG2D ligands. Initial evidence suggests that this model is relevant to human patients. Thus, antitumor therapies that target Bcl-2 harbor the risk of reducing tumor immunogenicity.
journal_name
Oncoimmunologyjournal_title
Oncoimmunologyauthors
Putz EM,Schuster C,Sexl Vdoi
10.4161/onci.19536subject
Has Abstractpub_date
2012-08-01 00:00:00pages
749-750issue
5eissn
2162-4011issn
2162-402Xpii
2012ONCOIMM0037journal_volume
1pub_type
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