Abstract:
:Fbxw7 has been identified as an oncosuppressor protein in many types of cancer. We have recently shown that loss of Fbxw7 in bone marrow-derived stromal cells (BMSCs) promotes cancer metastasis by increasing production of the chemokine CCL2, which attracts monocytic myeloid-derived suppressor cells (Mo-MDSCs) and macrophages to the metastatic niche.
journal_name
Oncoimmunologyjournal_title
Oncoimmunologyauthors
Yumimoto K,Nakayama KIdoi
10.1080/2162402X.2015.1022308subject
Has Abstractpub_date
2015-06-03 00:00:00pages
e1022308issue
8eissn
2162-4011issn
2162-402Xpii
1022308journal_volume
4pub_type
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