Glycaemic durability with dipeptidyl peptidase-4 inhibitors in type 2 diabetes: a systematic review and meta-analysis of long-term randomised controlled trials.

abstract：OBJECTIVES:To complete a 30-year interrupted time-series analysis of the impact of austerity-related and prosperity-related events on the occurrence of suicide across Greece. SETTING:Greece from 1 January 1983 to 31 December 2012. PARTICIPANTS:A total of 11 505 suicides, 9079 by men and 2426 by women, occurring in Gr...

journal_title：BMJ open

authors： Branas CC,Kastanaki AE,Michalodimitrakis M,Tzougas J,Kranioti EF,Theodorakis PN,Carr BG,Wiebe DJ

更新日期：2015-02-02 00:00:00

abstract：INTRODUCTION:High-flow nasal oxygen (HFNO) use in adults hospitalised with acute respiratory failure (ARF) is increasing. However, evidence to support widespread use of HFNO compared with non-invasive ventilation (NIV) and conventional oxygen therapy (COT) is unclear. This protocol describes the methods for a systemati...

journal_title：BMJ open

authors： Baldomero AK,Melzer A,Greer N,Majeski BN,Macdonald R,Wilt TJ

更新日期：2020-02-12 00:00:00

abstract：OBJECTIVE:To explore the perspectives of primary healthcare (PHC) professionals providing care to refugees through mainstream general practice. DESIGN:Qualitative exploratory design with semistructured interviews subjected to inductive thematic analysis. SETTING AND PARTICIPANTS:Nine general practices enrolled in the...

journal_title：BMJ open

authors： Richard L,Richardson G,Jaye C,Stokes T

更新日期：2019-12-31 00:00:00

abstract：INTRODUCTION:Many types of audits are commonly used in hospital care to promote quality improvements. However, the evidence on the effectiveness of audits is mixed. The objectives of this proposed realist review are (1) to understand how and why audits might, or might not, work in terms of delivering the intended outco...

journal_title：BMJ open

authors： Hut-Mossel L,Welker G,Ahaus K,Gans R

更新日期：2017-06-14 00:00:00

abstract：INTRODUCTION:Patients with an intracerebral haemorrhage are at increased risk of venous thromboembolism. Pharmacotherapy and pneumatic compression devices are capable of preventing venous thromboembolism, however both interventions have limitations. There are no head-to-head comparisons between these two interventions....

journal_title：BMJ open

authors： Yogendrakumar V,Lun R,Hutton B,Fergusson DA,Dowlatshahi D

更新日期：2018-11-05 00:00:00

abstract：INTRODUCTION:Excessive prescribing after surgery has contributed to a public health crisis of opioid addiction and overdose in North America. However, the value of prescribing opioids to manage postoperative pain after surgical discharge remains unclear. We propose a systematic review and meta-analysis to assess the ex...

journal_title：BMJ open

authors： El-Kefraoui C,Olleik G,Chay MA,Kouyoumdjian A,Nguyen-Powanda P,Rajabiyazdi F,Do U,Derksen A,Landry T,Amar-Zifkin A,Ramanakumar AV,Martel MO,Baldini G,Feldman L,Fiore JF Jr

更新日期：2020-02-02 00:00:00

abstract：INTRODUCTION:Age-related loss of muscle mass and strength, sarcopaenia, burdens many older adults. The process is accelerated with bed rest, protein intakes below requirements and the catabolic effect of certain illnesses. Thus, acutely ill, hospitalised older adults are particularly vulnerable. Protein supplementation...

journal_title：BMJ open

authors： Gade J,Beck AM,Bitz C,Christensen B,Klausen TW,Vinther A,Astrup A

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVES:One of Africa's most important challenges is to improve maternal and neonatal health. The identification of groups at highest risk for adverse pregnancy outcomes is important for developing and implementing targeted prevention programmes. This study assessed whether young adolescent girls constitute a group ...

journal_title：BMJ open

authors： Mombo-Ngoma G,Mackanga JR,González R,Ouedraogo S,Kakolwa MA,Manego RZ,Basra A,Rupérez M,Cot M,Kabanywany AM,Matsiegui PB,Agnandji ST,Vala A,Massougbodji A,Abdulla S,Adegnika AA,Sevene E,Macete E,Yazdanbakhsh M,Krems

更新日期：2016-06-29 00:00:00

abstract：OBJECTIVES:To systematically analyse the effect of pharmacological treatment of hypertension (HTN) on cognitive decline in older adults. METHODS:Randomised, placebo-controlled trials with a prespecified quantitative outcome of cognition and a pharmacological intervention for at least 12 months to treat HTN in older ad...

journal_title：BMJ open

authors： Gupta A,Perdomo S,Billinger S,Beddhu S,Burns J,Gronseth G

更新日期：2020-11-17 00:00:00

abstract：INTRODUCTION:Smoking remains the leading cause of preventable death in the USA but can be reduced through policy interventions. Computational models of smoking can provide estimates of the projected impact of tobacco control policies and can be used to inform public health decision making. We outline a protocol for sim...

journal_title：BMJ open

authors： Tam J,Levy DT,Jeon J,Clarke J,Gilkeson S,Hall T,Feuer EJ,Holford TR,Meza R

更新日期：2018-03-23 00:00:00

abstract：OBJECTIVES:Placenta or placental chorangioma could be the origin site of infantile haemangioma since they share various histochemical and genetic characteristics with placental vascular tissue. The aim of the current study was to investigate the association between chorangiomas and infantile haemangiomas in singleton a...

journal_title：BMJ open

authors： Sirotkina M,Douroudis K,Wahlgren CF,Westgren M,Papadogiannakis N

更新日期：2017-09-03 00:00:00

abstract：OBJECTIVES:Creation of linked mental health, social and education records for research to support evidence-based practice for regional mental health services. SETTING:The Clinical Record Interactive Search (CRIS) system was used to extract personal identifiers who accessed psychiatric services between September 2007 a...

journal_title：BMJ open

authors： Downs JM,Ford T,Stewart R,Epstein S,Shetty H,Little R,Jewell A,Broadbent M,Deighton J,Mostafa T,Gilbert R,Hotopf M,Hayes R

更新日期：2019-01-29 00:00:00

abstract：OBJECTIVES:Most studies reporting evidence of adverse effects of lead and cadmium on the ability to balance have been conducted in high-exposure groups or have included adults. The effects of prenatal exposure have not been well studied, nor have the effects in children been directly studied. The aim of the study was t...

journal_title：BMJ open

authors： Taylor CM,Humphriss R,Hall A,Golding J,Emond AM

更新日期：2015-12-30 00:00:00

abstract：INTRODUCTION:Sub-Saharan Africa remains the epicentre of the HIV pandemic, yet enormous knowledge gaps still exist to elicit a comprehensive portrait of multimorbidity and HIV linkage. This study aims to conduct a systematic meta-analysis of peer-reviewed literature to investigate the current status of multimorbidity e...

journal_title：BMJ open

authors： Oladimeji KE,Dzomba A,Adetokunboh O,Zungu L,Yaya S,Goon DT

更新日期：2020-12-12 00:00:00

abstract：OBJECTIVE:To determine levels of public registration for a cohort of clinical trials reviewed and given a favourable opinion by research ethics committees in the United Kingdom. STUDY DESIGN:Audit of records. SETTING:Clinical trials receiving a favourable ethics opinion between 1 January 2016 and 30 June 2016. MAIN ...

journal_title：BMJ open

authors： Denneny C,Bourne S,Kolstoe SE

更新日期：2019-02-21 00:00:00

abstract：OBJECTIVES:(1) To explain general practitioners' (GPs') approaches to prostate-specific antigen (PSA) testing and overdiagnosis; (2) to explain how GPs reason about their PSA testing routines and (3) to explain how these routines influence GPs' personal experience as clinicians. SETTING:Primary care practices in Austr...

journal_title：BMJ open

authors： Pickles K,Carter SM,Rychetnik L

更新日期：2015-03-17 00:00:00

abstract：OBJECTIVES:Multimorbidity is the presence of 2 or more medical conditions. This increasingly used assessment has not been assessed in a surgical population. The objectives of this study were to assess the prevalence of multimorbidity and its association with common outcome measures. DESIGN:A cross-sectional observatio...

journal_title：BMJ open

authors： Hewitt J,McCormack C,Tay HS,Greig M,Law J,Tay A,Asnan NH,Carter B,Myint PK,Pearce L,Moug SJ,McCarthy K,Stechman MJ

更新日期：2016-03-31 00:00:00

abstract：INTRODUCTION:Despite the strong relationship between smoking and health-related consequences, very few smokers quit. Heavy drinking is a significant risk factor for health consequences, and is implicated in persistent smoking and less success at quitting smoking. Self-efficacy (SE) to abstain from smoking is an importa...

journal_title：BMJ open

authors： Cohn A,Brandon T,Armeli S,Ehlke S,Bowers M

更新日期：2015-01-06 00:00:00

abstract：OBJECTIVE:Our cross-sectional study aimed at evaluating the diagnostic performance of Focused Assessment with Sonography for HIV-associated tuberculosis (FASH) to detect extrapulmonary tuberculosis in extremely resource-limited settings, with visceral leishmaniasis as a differential diagnosis with overlapping sonograph...

journal_title：BMJ open

authors： Bobbio F,Di Gennaro F,Marotta C,Kok J,Akec G,Norbis L,Monno L,Saracino A,Mazzucco W,Lunardi M

更新日期：2019-04-02 00:00:00

abstract：OBJECTIVES:Epidemiological studies evaluating the association between adiponectin levels and endometrial carcinoma risk have produced inconsistent results. Thus, a meta-analysis was conducted to assess the association between them. METHODS:Pertinent studies were identified by a search of PubMed and Web of Knowledge th...

journal_title：BMJ open

authors： Lin T,Zhao X,Kong WM

更新日期：2015-09-03 00:00:00

abstract：OBJECTIVES:Respiratory symptoms are associated with spirometry results but more strongly with smoking history, suggesting that alterations in the lung other than those revealed by spirometry contribute to cause symptoms. Smoking may cause obstruction of peripheral airways that is poorly detected by spirometry. The slop...

journal_title：BMJ open

authors： Olofson JY,Houltz B,Nilsson Tengelin M,Bake B

更新日期：2012-11-27 00:00:00

abstract：OBJECTIVES:People who are marginalised (medically underserved) experience significant health disparities and their voices are often 'seldom heard'. Interventions to improve professional awareness and engagement with these groups are urgently needed. This study uses a co-production approach to develop an online digital ...

journal_title：BMJ open

authors： Latif A,Waring J,Chen LC,Pollock K,Solomon J,Gulzar N,Gulzar S,Anderson E,Choudhary S,Abbasi N,Wharrad HJ,Anderson C

更新日期：2019-09-17 00:00:00

abstract：INTRODUCTION:Obesity is significant risk factor for venous thromboembolism (VTE); however, the related mechanisms remain unclear. Previous studies have suggested that this might be related to physical factors including anthropometric measures. We intend to conduct a systematic review and meta-analysis of prospective st...

journal_title：BMJ open

authors： Kaze AD,Bigna JJ,Nansseu JR,Noubiap JJ

更新日期：2018-03-31 00:00:00

abstract：OBJECTIVES:In response to public health concern about effects of arson at solid waste management plants in July 2012, we analysed vital statistics data to evaluate any potential effect on pregnancies at different gestational ages of pollutants emitted from the landfill on fire. SETTING:A community living near the larg...

journal_title：BMJ open

authors： Mazzucco W,Tavormina E,Macaluso M,Marotta C,Cusimano R,Alba D,Costantino C,Grammauta R,Cernigliaro A,Scondotto S,Vitale F

更新日期：2019-07-04 00:00:00

abstract：INTRODUCTION:Chemotherapy-induced peripheral neuropathy (CIPN) is a prevalent and clinically meaningful side effect of cancer treatment. CIPN is induced by neurotoxic agents, causing severe sensory and/or motor deficits, resulting in disability and poor recovery, reducing patients' quality of life and limiting medical ...

journal_title：BMJ open

authors： Streckmann F,Hess V,Bloch W,Décard BF,Ritzmann R,Lehmann HC,Balke M,Koliamitra C,Oschwald V,Elter T,Zahner L,Donath L,Roth R,Faude O

更新日期：2019-04-24 00:00:00

abstract：OBJECTIVES:The difference between income quintiles in health is relatively well accepted by the general public as a measure of health inequality. However, the slope index of inequality (SII) in health reflects the patterns of all social groups, including the middle 60%, and it could therefore be considered more academi...

journal_title：BMJ open

authors： Khang YH,Lim D,Bahk J,Kim I,Kang HY,Chang Y,Jung-Choi K

更新日期：2019-06-27 00:00:00

abstract：BACKGROUND:The health hazards associated with the use of smokeless tobacco (SLT) are similar to those of smoking. However, unlike smoking, limited initiatives have been taken to control the use of SLT, despite its widespread use in South and Southeast Asian countries including Bangladesh. It is therefore important to e...

journal_title：BMJ open

authors： Mia MN,Hanifi SM,Rahman MS,Sultana A,Hoque S,Bhuiya A

更新日期：2017-01-25 00:00:00

abstract：OBJECTIVE:Model the impact of targets for obesity, diabetes, raised blood pressure, tobacco use, salt intake, physical inactivity and harmful alcohol use, as outlined in the Global Non-Communicable Disease Action Plan 2013-2020, on mortality and morbidity in the UK population. DESIGN:Dynamic population modelling study...

journal_title：BMJ open

authors： Cobiac LJ,Scarborough P

更新日期：2017-04-04 00:00:00

abstract：OBJECTIVE:In October 2013, the South Korean government introduced an incentive programme to increase the availability of Saturday treatment at clinics, hoping to increase the role of primary care providers as gatekeepers to medical care. To the best of our knowledge, no one has yet investigated this programme's effect ...

journal_title：BMJ open

authors： Ha HJ,Han KT,Kim SJ,Sohn TY,Jeon B,Park EC

更新日期：2016-06-09 00:00:00

abstract：INTRODUCTION:It has been reported that post-hospitalisation behaviour change (PHBC) occurs in over 50% of children undergoing a general anaesthetic and manifests as behaviours such as sleep and eating disorders, defiance of authority, nightmares, enuresis and temper tantrums. The effect is usually short-lived (2-4 week...

journal_title：BMJ open

authors： Lee-Archer P,McBride C,Paterson R,Reade M,Regli-von Ungern-Sternberg B,Long D

更新日期：2018-04-17 00:00:00