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Prevalence of multimorbidity and its association with outcomes in older emergency general surgical patients: an observational study.

Abstract：

OBJECTIVES:Multimorbidity is the presence of 2 or more medical conditions. This increasingly used assessment has not been assessed in a surgical population. The objectives of this study were to assess the prevalence of multimorbidity and its association with common outcome measures. DESIGN:A cross-sectional observational study. SETTING:A UK-based multicentre study, included participants between July and October 2014. PARTICIPANTS:Consecutive emergency (non-elective) general surgical patients admitted to hospital, aged over 65 years. OUTCOME MEASURES:The outcome measures were (1) the prevalence of multimorbidity and (2) the association between multimorbidity and frailty; the rate and severity of surgery; length of hospital stay; readmission to hospital within 30 days of discharge; and death at 30 and 90 days. RESULTS:Data were collected on 413 participants aged 65-98 years (median 77 years, (IQR (70-84)). 51.6% (212/413) participants were women. Multimorbidity was present in 74% (95% CI 69.7% to 78.2%) of the population and increased with age (p<0.0001). Multimorbidity was associated with increasing frailty (p for trend <0.0001). People with multimorbidity underwent surgery as often as those without multimorbidity, including major surgery (p=0.03). When comparing multimorbid people with those without multimorbidity, we found no association between length of hospital stay (median 5 days, IQR (1-54), vs 6 days (1-47), (p=0.66)), readmission to hospital (64 (21.1%) vs 18 (16.8%) (p=0.35)), death at 30 days (14 (4.6%) vs 6 (5.6%) (p=0.68)) or 90-day mortality (28 (9.2%) vs 8 (7.6%) (p=0.60)). CONCLUSIONS AND IMPLICATIONS:Multimorbidity is common. Nearly three-quarters of this older emergency general surgical population had 2 or more chronic medical conditions. It was strongly associated with age and frailty, and was not a barrier to surgical intervention. Multimorbidity showed no associations across a range of outcome measures, as it is currently defined. Multimorbidity should not be relied on as a useful clinical tool in guidelines or policies for older emergency surgical patients.

journal_name

BMJ Open

journal_title

BMJ open

authors

Hewitt J,McCormack C,Tay HS,Greig M,Law J,Tay A,Asnan NH,Carter B,Myint PK,Pearce L,Moug SJ,McCarthy K,Stechman MJ

doi

10.1136/bmjopen-2015-010126

subject

Has Abstract

pub_date

2016-03-31 00:00:00

pages

e010126

issue

3

issn

2044-6055

pii

bmjopen-2015-010126

journal_volume

6

pub_type

杂志文章,多中心研究

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