Cell-free DNA and outcome in sepsis.

abstract：:Those involved in the airway management of COVID-19 patients are particularly at risk. Here, we describe a practical, stepwise protocol for safe in-hospital airway management in patients with suspected or confirmed COVID-19 infection. ...

journal_title：Critical care (London, England)

authors： Sullivan EH,Gibson LE,Berra L,Chang MG,Bittner EA

更新日期：2020-06-05 00:00:00

abstract：INTRODUCTION:Evidence suggests that dying patients' physical and emotional suffering is inadequately treated in intensive care units. Although there are recommendations regarding decisions to forgo life-sustaining therapy, deciding on withdrawal of life support is difficult, and it is also difficult to decide who shoul...

journal_title：Critical care (London, England)

authors： Fumis RR,Deheinzelin D

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Lung protective ventilation requires low tidal volume and suitable positive end-expiratory pressure (PEEP). To date, few methods have been accepted for clinical use to set the appropriate PEEP. The aim of this study was to test the feasibility of PEEP titration guided by ventilation homogeneity using the g...

journal_title：Critical care (London, England)

authors： Zhao Z,Steinmann D,Frerichs I,Guttmann J,Möller K

更新日期：2010-01-01 00:00:00

abstract：:Primary or secondary infection of necrotized areas by enteral bacteria is considered a primary cause of mortality in patients with severe acute pancreatitis (SAP). Indeed, 20-30% of patients die during the course of the disease from multiple organ dysfunction after infection. This is why strategies such as antibiotic ...

journal_title：Critical care (London, England)

authors： Gerlach H

更新日期：2004-12-01 00:00:00

abstract：:The diagnosis of patients presenting to the emergency department with acute heart failure (AHF) is challenging due to the similarity of AHF symptoms to other conditions such as chronic obstructive pulmonary disease and pneumonia. Additionally, because AHF is most common in an older population, the presentation of coex...

journal_title：Critical care (London, England)

authors： Peacock WF,Cannon CM,Singer AJ,Hiestand BC

更新日期：2015-11-10 00:00:00

abstract：:The aim of perioperative haemodilution is to reduce loss of red blood cells during elective surgery. The oncotic and molecular characteristics of the various plasma substitutes employed determine how effectively normovolaemia is maintained, and their non-oncotic effects include alterations in microvascular perfusion. ...

journal_title：Critical care (London, England)

authors： Creagh-Brown BC,Evans TW

更新日期：2008-01-01 00:00:00

abstract：INTRODUCTION:The early aggressive management of the acute coagulopathy of trauma may improve survival in the trauma population. However, the timely identification of lethal exsanguination remains challenging. This study validated six scoring systems and algorithms to stratify patients for the risk of massive transfusio...

journal_title：Critical care (London, England)

authors： Brockamp T,Nienaber U,Mutschler M,Wafaisade A,Peiniger S,Lefering R,Bouillon B,Maegele M,TraumaRegister DGU.

更新日期：2012-07-20 00:00:00

abstract：BACKGROUND:Endothelial hyperpermeability following cardiopulmonary bypass (CPB) contributes to microcirculatory perfusion disturbances and postoperative complications after cardiac surgery. We investigated the postoperative course of renal and pulmonary endothelial barrier function and the association with microcircula...

journal_title：Critical care (London, England)

authors： Dekker NAM,van Leeuwen ALI,van Strien WWJ,Majolée J,Szulcek R,Vonk ABA,Hordijk PL,Boer C,van den Brom CE

更新日期：2019-04-11 00:00:00

abstract：INTRODUCTION:Early multimodal treatment of severe sepsis, including the use of drotrecogin alfa (activated) (DrotAA) when indicated, is considered essential for optimum outcome. However, predicting which infected patients will progress to severe sepsis and the need for aggressive intervention continues to be problemati...

journal_title：Critical care (London, England)

authors： Hodder RV,Hall R,Russell JA,Fisher HN,Lee B

更新日期：2009-01-01 00:00:00

abstract：:There are many controversial issues surrounding ethics in study design and conduct of human subjects research. In this review we briefly touch on the origin of ethics in clinical research and how the current regulations and standards came into practice. We then discuss current controversies regarding informed consent,...

journal_title：Critical care (London, England)

authors： Huang DT,Hadian M

更新日期：2006-01-01 00:00:00

abstract：:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2020. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2020. Further information about the Annual Update in Intensive Care and Emergency Medicine is available ...

journal_title：Critical care (London, England)

authors： Bassetti M,Bandera A,Gori A

更新日期：2020-03-24 00:00:00

abstract：INTRODUCTION:Staphylococcus (S.) aureus has emerged as an important cause of necrotizing pneumonia. Lung injury during S. aureus pneumonia may be enhanced by local release of damage associated molecular patterns such as high-mobility group box 1 (HMGB1). In the current study we sought to determine the functional role o...

journal_title：Critical care (London, England)

authors： Achouiti A,van der Meer AJ,Florquin S,Yang H,Tracey KJ,van 't Veer C,de Vos AF,van der Poll T

更新日期：2013-12-16 00:00:00

abstract：INTRODUCTION:Anemia is a frequently encountered problem during inflammation. Hepcidin is an interleukin-6 (IL-6)-induced key modulator of inflammation-associated anemia. Human sepsis is a prototypical inflammatory syndrome, often complicated by the development of anemia. However, the association between inflammation, h...

journal_title：Critical care (London, England)

authors： van Eijk LT,Kroot JJ,Tromp M,van der Hoeven JG,Swinkels DW,Pickkers P

更新日期：2011-01-01 00:00:00

abstract：:Since the inception of blood banking, refinements in laboratory processes have allowed for progressively longer storage times of red blood cells. Whilst advantageous for the logistics of stock management, the clinical impact of the duration of red blood cell storage prior to transfusion remains uncertain, and a topic ...

journal_title：Critical care (London, England)

authors： Laurie J,Wyncoll D,Harrison C

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:Appropriate care for patients with tracheostomies in hospital settings is an important issue. Each year more than 7000 patients receive tracheostomies in Australia and New Zealand alone. Many of these tracheostomy patients commence their care in the intensive care unit (ICU) and once stabilised are then tr...

journal_title：Critical care (London, England)

authors： Garrubba M,Turner T,Grieveson C

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:Passive leg raising (PLR) is a simple reversible maneuver that mimics rapid fluid loading and increases cardiac preload. The effects of this endogenous volume expansion on stroke volume enable the testing of fluid responsiveness with accuracy in spontaneously breathing patients. However, this maneuver requ...

journal_title：Critical care (London, England)

authors： Biais M,Vidil L,Sarrabay P,Cottenceau V,Revel P,Sztark F

更新日期：2009-01-01 00:00:00

abstract：INTRODUCTION:It is recognized that administration of insulin with glucose decreases catabolic response in sepsis. The aim of the present study was to compare the effects of two levels of insulinaemia on glucose metabolism and energy expenditure in septic patients and volunteers. METHODS:Glucose uptake, oxidation and s...

journal_title：Critical care (London, England)

authors： Rusavy Z,Sramek V,Lacigova S,Novak I,Tesinsky P,Macdonald IA

更新日期：2004-08-01 00:00:00

abstract：INTRODUCTION:This small observational study was motivated by our belief that scaling the tidal volume in mechanically ventilated patients to the size of the injured lung is safer and more 'physiologic' than scaling it to predicted body weight, i.e. its size before it was injured. We defined Total Lung Capacity (TLC) as...

journal_title：Critical care (London, England)

authors： Mattingley JS,Holets SR,Oeckler RA,Stroetz RW,Buck CF,Hubmayr RD

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Takotsubo cardiomyopathy (TCM) is a life-threatening systemic consequence early after subarachnoid hemorrhage (SAH), but precise hemodynamics and related outcome have not been studied. The purpose of this study was to investigate the TCM-induced cardiac function by transpulmonary thermodilution and its imp...

journal_title：Critical care (London, England)

authors： Mutoh T,Kazumata K,Terasaka S,Taki Y,Suzuki A,Ishikawa T

更新日期：2014-08-12 00:00:00

abstract：:Tight glycemic control has engendered large numbers of investigations, with conflicting results. The world has largely embraced intensive insulin as a practice, but applies this therapy with great variability in the manner of glucose control and measurement. The present commentary reviews what we actually know with ce...

journal_title：Critical care (London, England)

authors： Nasraway SA Jr,Rattan R

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:New technology using partial carbon dioxide rebreathing has been developed to measure cardiac output. Because rebreathing increases respiratory effort, we investigated whether a newly developed system with 35 s rebreathing causes a lesser increase in respiratory effort under partial ventilatory support tha...

journal_title：Critical care (London, England)

authors： Tachibana K,Imanaka H,Takeuchi M,Nishida T,Takauchi Y,Nishimura M

更新日期：2005-10-05 00:00:00

abstract：INTRODUCTION:Resuscitation with saline is a standard initial response to hypotension or shock of almost any cause. Saline resuscitation is thought to generate an increase in cardiac output through a preload-dependent (increased end-diastolic volume) augmentation of stroke volume. We sought to confirm this to be the mec...

journal_title：Critical care (London, England)

authors： Kumar A,Anel R,Bunnell E,Zanotti S,Habet K,Haery C,Marshall S,Cheang M,Neumann A,Ali A,Kavinsky C,Parrillo JE

更新日期：2004-06-01 00:00:00

abstract：INTRODUCTION:Fever is associated with a poor outcome in severely brain-injured patients, and its control is one of the therapies used in this condition. But, fever suppression may promote infection, and severely brain-injured patients are frequently exposed to infectious diseases, particularly ventilator-associated pne...

journal_title：Critical care (London, England)

authors： Launey Y,Nesseler N,Le Cousin A,Feuillet F,Garlantezec R,Mallédant Y,Seguin P

更新日期：2014-12-15 00:00:00

abstract：INTRODUCTION:Partial pressure of end-tidal carbon dioxide (PetCO2) during cardiopulmonary resuscitation (CPR) correlates with cardiac output and consequently has a prognostic value in CPR. In our previous study we confirmed that initial PetCO2 value was significantly higher in asphyxial arrest than in ventricular fibri...

journal_title：Critical care (London, England)

authors： Lah K,Križmarić M,Grmec S

更新日期：2011-01-01 00:00:00

abstract：INTRODUCTION:Delirium occurs in most ventilated patients and is independently associated with more deaths, longer stay, and higher cost. Guidelines recommend monitoring of delirium in all intensive care unit (ICU) patients, though few data exist in non-ventilated patients. The study objective was to determine the relat...

journal_title：Critical care (London, England)

authors： Thomason JW,Shintani A,Peterson JF,Pun BT,Jackson JC,Ely EW

更新日期：2005-08-01 00:00:00

abstract：:The pulmonary artery catheter (PAC) was introduced in 1971 for the assessment of heart function at the bedside. Since then it has generated much enthusiasm and controversy regarding the benefits and potential harms caused by this invasive form of hemodynamic monitoring. This review discusses all clinical studies condu...

journal_title：Critical care (London, England)

authors： Hadian M,Pinsky MR

更新日期：2006-01-01 00:00:00

abstract：:Prediction of ventilation weaning outcome in children is important, as unsuccessful extubation increases both morbidity and mortality. Adult weaning criteria are poor predictors of weaning outcome in children for several possible reasons: the length of mechanical ventilation is generally much shorter, and the weaning ...

journal_title：Critical care (London, England)

authors： Schindler MB

更新日期：2005-01-01 00:00:00

abstract：:This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2019. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2019 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available...

journal_title：Critical care (London, England)

authors： Milford EM,Reade MC

更新日期：2019-03-09 00:00:00

abstract：INTRODUCTION:The diagnostic and prognostic value of arterial blood gas analysis (ABGA) parameters in unselected patients presenting with acute dyspnea to the Emergency Department (ED) is largely unknown. METHODS:We performed a post-hoc analysis of two different prospective studies to investigate the diagnostic and pro...

journal_title：Critical care (London, England)

authors： Burri E,Potocki M,Drexler B,Schuetz P,Mebazaa A,Ahlfeld U,Balmelli C,Heinisch C,Noveanu M,Breidthardt T,Schaub N,Reichlin T,Mueller C

更新日期：2011-01-01 00:00:00

abstract：:The epidemiology of severe acute renal failure has dramatically changed in the past decade. Its leading cause is sepsis and the syndrome develops mostly in the intensive care unit as part of multiple organ dysfunction syndrome. After the significant improvements obtained from the mid 1970s to the mid 1990s, the past d...

journal_title：Critical care (London, England)

authors： Ronco C

更新日期：2006-02-01 00:00:00